-
1
-
-
0024368359
-
Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
-
D.G. Ando J. Clayton D. Kono J.L. Urban E.E. Sercarz 1989 Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype Cell Immunol 124 132 143
-
(1989)
Cell Immunol
, vol.124
, pp. 132-143
-
-
Ando, D.G.1
Clayton, J.2
Kono, D.3
Urban, J.L.4
Sercarz, E.E.5
-
3
-
-
2542418993
-
High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay
-
M.P. Crawford S.X. Yan S.B. Ortega R.S. Mehta R.E. Hewitt D.A. Price 2004 High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay Blood 103 4222 4231
-
(2004)
Blood
, vol.103
, pp. 4222-4231
-
-
Crawford, M.P.1
Yan, S.X.2
Ortega, S.B.3
Mehta, R.S.4
Hewitt, R.E.5
Price, D.A.6
-
4
-
-
0031933496
-
The cytokine storm in multiple sclerosis
-
H. Link 1998 The cytokine storm in multiple sclerosis Mult Scler 4 12 15
-
(1998)
Mult Scler
, vol.4
, pp. 12-15
-
-
Link, H.1
-
5
-
-
0345358584
-
The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
-
G. Trinchieri S. Pflanz R.A. Kastelein 2003 The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses Immunity 19 641 644
-
(2003)
Immunity
, vol.19
, pp. 641-644
-
-
Trinchieri, G.1
Pflanz, S.2
Kastelein, R.A.3
-
6
-
-
35649000947
-
IL-12/IFN-γ/NO axis plays critical role in development of Th1-mediated experimental autoimmune encephalomyelitis
-
B.G. Xiao C.G. Ma L.Y. Xu H. Link C.Z. Lu 2008 IL-12/IFN-γ/NO axis plays critical role in development of Th1-mediated experimental autoimmune encephalomyelitis Mol Immunol 45 1191 1196
-
(2008)
Mol Immunol
, vol.45
, pp. 1191-1196
-
-
Xiao, B.G.1
Ma, C.G.2
Xu, L.Y.3
Link, H.4
Lu, C.Z.5
-
7
-
-
51249090471
-
T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis
-
C.J. Hedegaard M. Krakauer K. Bendtzen H. Lund F. Sellebjerg C.H. Nielsen 2008 T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis Immunology 125 161 169
-
(2008)
Immunology
, vol.125
, pp. 161-169
-
-
Hedegaard, C.J.1
Krakauer, M.2
Bendtzen, K.3
Lund, H.4
Sellebjerg, F.5
Nielsen, C.H.6
-
8
-
-
25144520110
-
Characterizing the mechanisms of progression in multiple sclerosis: Evidence and new hypotheses for future directions
-
E.M. Frohman M. Filippi O. Stuve S.G. Waxman J. Corboy J.T. Phillips 2005 Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions Arch Neurol 62 1345 1356
-
(2005)
Arch Neurol
, vol.62
, pp. 1345-1356
-
-
Frohman, E.M.1
Filippi, M.2
Stuve, O.3
Waxman, S.G.4
Corboy, J.5
Phillips, J.T.6
-
9
-
-
0032525044
-
A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice
-
M. Falcone A.J. Rajan B.R. Bloom C.F. Brosnan 1998 A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice J Immunol 160 4822 4830
-
(1998)
J Immunol
, vol.160
, pp. 4822-4830
-
-
Falcone, M.1
Rajan, A.J.2
Bloom, B.R.3
Brosnan, C.F.4
-
10
-
-
0032193696
-
IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10 and IL-4 deficient and transgenic mice
-
E. Bettelli M.P. Das E.D. Howard H.L. Weiner R.A. Sobel V.K. Kuchroo 1998 IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10 and IL-4 deficient and transgenic mice J Immunol 161 3299 3306
-
(1998)
J Immunol
, vol.161
, pp. 3299-3306
-
-
Bettelli, E.1
Das, M.P.2
Howard, E.D.3
Weiner, H.L.4
Sobel, R.A.5
Kuchroo, V.K.6
-
11
-
-
0037406714
-
Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells
-
P.L. Vieira H.C. Heystek J. Wormmeester E.A. Wierenga M.L. Kapsenberg 2003 Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells J Immunol 170 4483 4488
-
(2003)
J Immunol
, vol.170
, pp. 4483-4488
-
-
Vieira, P.L.1
Heystek, H.C.2
Wormmeester, J.3
Wierenga, E.A.4
Kapsenberg, M.L.5
-
12
-
-
0242468114
-
IL-5 deficient mice are susceptible to experimental autoimmune encephlomyelitis
-
C. Weir C.C. Bernard B.T. Backstrom 2003 IL-5 deficient mice are susceptible to experimental autoimmune encephlomyelitis Int Immunol 15 1283 1289
-
(2003)
Int Immunol
, vol.15
, pp. 1283-1289
-
-
Weir, C.1
Bernard, C.C.2
Backstrom, B.T.3
-
13
-
-
0028960035
-
Cytokines and murine autoimmune encephalomyelitis: Inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system
-
D.O. Willenborg S.A. Fordham W.B. Cowden I.A. Ramshaw 1995 Cytokines and murine autoimmune encephalomyelitis: Inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system Scand J Immunol 41 31 41
-
(1995)
Scand J Immunol
, vol.41
, pp. 31-41
-
-
Willenborg, D.O.1
Fordham, S.A.2
Cowden, W.B.3
Ramshaw, I.A.4
-
15
-
-
48249148236
-
IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis
-
S. Serada M. Fujimoto M. Mihara N. Koike Y. Ohsugi S. Nomura 2008 IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis Proc Natl Acad Sci 105 9041 9046
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 9041-9046
-
-
Serada, S.1
Fujimoto, M.2
Mihara, M.3
Koike, N.4
Ohsugi, Y.5
Nomura, S.6
-
16
-
-
57349088882
-
Monocyte chemokine protein-1 mRNA expression in experimental allergic encephalomyelitis rats treated with or without triptolide
-
C.G. Ma Y. Liu T.H. Ma H. Liu L.Y. Liang L.H. Zhang 2005 Monocyte chemokine protein-1 mRNA expression in experimental allergic encephalomyelitis rats treated with or without triptolide J Neurol Sci 238 234
-
(2005)
J Neurol Sci
, vol.238
, pp. 234
-
-
Ma, C.G.1
Liu, Y.2
Ma, T.H.3
Liu, H.4
Liang, L.Y.5
Zhang, L.H.6
-
17
-
-
5144222298
-
Specific antigen vaccination to treat autoimmune disease
-
H. McDevitt 2004 Specific antigen vaccination to treat autoimmune disease Proc Natl Acad Sci 101 14627 14630
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 14627-14630
-
-
McDevitt, H.1
-
18
-
-
0036498604
-
The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis
-
G.X. Zhang H. Xu M. Kishi D. Calida A. Rostami 2002 The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis J Immunol 168 2501 2507
-
(2002)
J Immunol
, vol.168
, pp. 2501-2507
-
-
Zhang, G.X.1
Xu, H.2
Kishi, M.3
Calida, D.4
Rostami, A.5
-
19
-
-
0035554898
-
Multiple sclerosis: A two-stage disease
-
L. Steinman 2001 Multiple sclerosis: a two-stage disease Nat Immunol 2 762 764
-
(2001)
Nat Immunol
, vol.2
, pp. 762-764
-
-
Steinman, L.1
-
20
-
-
0038297356
-
Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes
-
J. Cabarrocas J. Bauer E. Piaggio R. Liblau H. Lassmann 2003 Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes Eur J Immunol 33 1174 1182
-
(2003)
Eur J Immunol
, vol.33
, pp. 1174-1182
-
-
Cabarrocas, J.1
Bauer, J.2
Piaggio, E.3
Liblau, R.4
Lassmann, H.5
-
21
-
-
12344280009
-
Specificity, magnitude, and kinetics of MOG-specific CD8(+)T cell responses during experimental autoimmune encephalomyelitis
-
M.L. Ford B.D. Evavold 2005 Specificity, magnitude, and kinetics of MOG-specific CD8(+)T cell responses during experimental autoimmune encephalomyelitis Eur J Immunol 35 76 85
-
(2005)
Eur J Immunol
, vol.35
, pp. 76-85
-
-
Ford, M.L.1
Evavold, B.D.2
-
22
-
-
0031891009
-
Cytokine production and surface marker expression in acute and stable multiple sclerosis: Altered IL-12 production and augmented signaling lymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiple sclerosis
-
P. Ferrante M.L. Fusi M. Saresella D. Caputo M. Biasin D. Trabattoni 1998 Cytokine production and surface marker expression in acute and stable multiple sclerosis: altered IL-12 production and augmented signaling lymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiple sclerosis J Immunol 160 1514 1521
-
(1998)
J Immunol
, vol.160
, pp. 1514-1521
-
-
Ferrante, P.1
Fusi, M.L.2
Saresella, M.3
Caputo, D.4
Biasin, M.5
Trabattoni, D.6
-
23
-
-
0034633769
-
Apoptosis mediators FasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS
-
W.X. Huang M.P. Huang M.A. Gomes J. Hillert 2000 Apoptosis mediators FasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS Neurology 55 928 934
-
(2000)
Neurology
, vol.55
, pp. 928-934
-
-
Huang, W.X.1
Huang, M.P.2
Gomes, M.A.3
Hillert, J.4
-
24
-
-
0031253737
-
Fas-and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
-
H. Waldner R.A. Sobel E. Howard V.K. Kuchroo 1997 Fas-and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis J Immunol 159 3100 3103
-
(1997)
J Immunol
, vol.159
, pp. 3100-3103
-
-
Waldner, H.1
Sobel, R.A.2
Howard, E.3
Kuchroo, V.K.4
-
25
-
-
33846295564
-
Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years
-
L. Lopatinskaya J. Zwemmer B. Uitdehaag K. Lucas C. Polman L. Nagelkerken 2006 Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years Mult Scler 12 704 709
-
(2006)
Mult Scler
, vol.12
, pp. 704-709
-
-
Lopatinskaya, L.1
Zwemmer, J.2
Uitdehaag, B.3
Lucas, K.4
Polman, C.5
Nagelkerken, L.6
-
26
-
-
27144460509
-
Apoptosis of oligodendrocytes via Fas and TNF-R1 is a key event in the induction of experimental autoimmune encephalomyelitis
-
N. Hövelmeyer Z. Hao K. Kranidioti G. Kassiotis T. Buch F. Frommer 2005 Apoptosis of oligodendrocytes via Fas and TNF-R1 is a key event in the induction of experimental autoimmune encephalomyelitis J Immunol 175 5875 5884
-
(2005)
J Immunol
, vol.175
, pp. 5875-5884
-
-
Hövelmeyer, N.1
Hao, Z.2
Kranidioti, K.3
Kassiotis, G.4
Buch, T.5
Frommer, F.6
-
28
-
-
35648938148
-
Diminished myelin-specific T cell activation associated with increase in CTLA4 and Fas molecules in multiple sclerosis patients treated with IFN-beta
-
D.E. Hallal-Longo S.R. Mirandola E.C. Oliveira A.S. Farias F.G. Pereira I.L. Metze 2007 Diminished myelin-specific T cell activation associated with increase in CTLA4 and Fas molecules in multiple sclerosis patients treated with IFN-beta J Interferon Cytokine Res 27 865 873
-
(2007)
J Interferon Cytokine Res
, vol.27
, pp. 865-873
-
-
Hallal-Longo, D.E.1
Mirandola, S.R.2
Oliveira, E.C.3
Farias, A.S.4
Pereira, F.G.5
Metze, I.L.6
-
29
-
-
0035378755
-
The molecular and cellular pathology of inflammatory muscle diseases
-
M.C. Dalakas 2001 The molecular and cellular pathology of inflammatory muscle diseases Curr Opin Pharmacol 1 300 306
-
(2001)
Curr Opin Pharmacol
, vol.1
, pp. 300-306
-
-
Dalakas, M.C.1
-
31
-
-
49649111913
-
B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: Implications for the lesion pathogenesis of multiple sclerosis
-
S. Ortler C. Leder M. Mittelbronn A.L. Zozulya P.A. Knolle L. Chen 2008 B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: Implications for the lesion pathogenesis of multiple sclerosis Eur J Immunol 38 1734 1744
-
(2008)
Eur J Immunol
, vol.38
, pp. 1734-1744
-
-
Ortler, S.1
Leder, C.2
Mittelbronn, M.3
Zozulya, A.L.4
Knolle, P.A.5
Chen, L.6
-
32
-
-
33645243957
-
Structural insight into the role of myelin basic protein in multiple sclerosis
-
C. Husted 2006 Structural insight into the role of myelin basic protein in multiple sclerosis Proc Natl Acad Sci 103 4339 4340
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 4339-4340
-
-
Husted, C.1
-
33
-
-
0344244785
-
Components in multiple sclerosis cerebrospinal fluid that are detected by radioimmunoassay for myelin basic protein
-
J.H. Carson E. Barbarese P.E. Braun T.A. McPherson 1978 Components in multiple sclerosis cerebrospinal fluid that are detected by radioimmunoassay for myelin basic protein Proc Natl Acad Sci 75 1976 1978
-
(1978)
Proc Natl Acad Sci
, vol.75
, pp. 1976-1978
-
-
Carson, J.H.1
Barbarese, E.2
Braun, P.E.3
McPherson, T.A.4
-
34
-
-
0021966856
-
T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination
-
S. Zamvil P. Nelson J. Trotter D. Mitchell R. Knobler R. Fritz 1985 T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination Nature 317 355 358
-
(1985)
Nature
, vol.317
, pp. 355-358
-
-
Zamvil, S.1
Nelson, P.2
Trotter, J.3
Mitchell, D.4
Knobler, R.5
Fritz, R.6
-
36
-
-
0031110114
-
Chemokine and matrix metalloproteinase secretion by myelin proteolipid protein specific CD8+ T cells: Potential roles in inflammation
-
W.E. Biddison D.D. Taub W.W. Cruikshank D.M. Center E.W. Connor K. Honma 1997 Chemokine and matrix metalloproteinase secretion by myelin proteolipid protein specific CD8+ T cells: potential roles in inflammation J Immunol 158 3046 3053
-
(1997)
J Immunol
, vol.158
, pp. 3046-3053
-
-
Biddison, W.E.1
Taub, D.D.2
Cruikshank, W.W.3
Center, D.M.4
Connor, E.W.5
Honma, K.6
-
37
-
-
25444464602
-
Myelin basic proteinprimed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: Implications for gender bias in multiple sclerosis
-
S. Dasgupta M. Jana X.J. Liu K. Pahan 2005 Myelin basic proteinprimed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis J Biol Chem 280 32609 32617
-
(2005)
J Biol Chem
, vol.280
, pp. 32609-32617
-
-
Dasgupta, S.1
Jana, M.2
Liu, X.J.3
Pahan, K.4
-
39
-
-
23744454283
-
Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange
-
M. Keegan F. König R. McClelland W. Brück Y. Morales A. Bitsch 2005 Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange Lancet 366 579 582
-
(2005)
Lancet
, vol.366
, pp. 579-582
-
-
Keegan, M.1
König, F.2
McClelland, R.3
Brück, W.4
Morales, Y.5
Bitsch, A.6
-
40
-
-
0027733797
-
The demyelinating potential of antibodies to myelin oligoden-drocyte glycoprotein is related to their ability to fix complement
-
S.J. Piddlesden H. Lassmann F. Zimprich B.P. Morgan C. Linington 1993 The demyelinating potential of antibodies to myelin oligoden-drocyte glycoprotein is related to their ability to fix complement Am J Pathol 143 555 564
-
(1993)
Am J Pathol
, vol.143
, pp. 555-564
-
-
Piddlesden, S.J.1
Lassmann, H.2
Zimprich, F.3
Morgan, B.P.4
Linington, C.5
-
41
-
-
33144474262
-
Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis
-
P.H. Lalive T. Menge C. Delarasse B. Della Gaspera D. Pham-Dinh P. Villoslada 2006 Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis Proc Natl Acad Sci 103 2280 2285
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 2280-2285
-
-
Lalive, P.H.1
Menge, T.2
Delarasse, C.3
Della Gaspera, B.4
Pham-Dinh, D.5
Villoslada, P.6
-
42
-
-
0035283493
-
The fine specificity of the myelin oligodendrocyte glycoprotein autoantibody response in patients with multiple sclerosis and normal healthy controls
-
C.G. Haase J. Guggenmos U. Brehm M. Andersson T. Olsson M. Reindl 2001 The fine specificity of the myelin oligodendrocyte glycoprotein autoantibody response in patients with multiple sclerosis and normal healthy controls J Neuroimmunol 114 220 225
-
(2001)
J Neuroimmunol
, vol.114
, pp. 220-225
-
-
Haase, C.G.1
Guggenmos, J.2
Brehm, U.3
Andersson, M.4
Olsson, T.5
Reindl, M.6
-
44
-
-
23944519424
-
Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
-
E. Zappia S. Casazza E. Pedemonte F. Benvenuto I. Bonanni E. Gerdoni 2005 Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy Blood 106 1755 1761
-
(2005)
Blood
, vol.106
, pp. 1755-1761
-
-
Zappia, E.1
Casazza, S.2
Pedemonte, E.3
Benvenuto, F.4
Bonanni, I.5
Gerdoni, E.6
-
45
-
-
20144368500
-
Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: Impact on disease activity and quality of life
-
R. Saccardi G.L. Mancardi A. Solari A. Bosi P. Bruzzi P. DiBartolomeo 2005 Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life Blood 105 2601 2607
-
(2005)
Blood
, vol.105
, pp. 2601-2607
-
-
Saccardi, R.1
Mancardi, G.L.2
Solari, A.3
Bosi, A.4
Bruzzi, P.5
Dibartolomeo, P.6
|