메뉴 건너뛰기




Volumn 45, Issue 4, 2008, Pages 1191-1196

IL-12/IFN-γ/NO axis plays critical role in development of Th1-mediated experimental autoimmune encephalomyelitis

Author keywords

Experimental autoimmune encephalomyelitis; IFN R ; IL 12 ; Nitric oxide; NOS2

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; MOG 35 55 PROTEIN; NITRIC OXIDE; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 35649000947     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.07.003     Document Type: Article
Times cited : (39)

References (25)
  • 1
    • 0032828455 scopus 로고    scopus 로고
    • Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis
    • Allione A., Bernabei P., Bosticardo M., Ariotti S., Forni G., and Novelli F. Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis. J. Immunol. 163 (1999) 4182-4191
    • (1999) J. Immunol. , vol.163 , pp. 4182-4191
    • Allione, A.1    Bernabei, P.2    Bosticardo, M.3    Ariotti, S.4    Forni, G.5    Novelli, F.6
  • 2
    • 0031569219 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis
    • Brenner T., Brocke S., Szafer F., Sobel R.A., Parkinson J.F., Perez D.H., and Steinman L. Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis. J. Immunol. 158 (1997) 2940-2946
    • (1997) J. Immunol. , vol.158 , pp. 2940-2946
    • Brenner, T.1    Brocke, S.2    Szafer, F.3    Sobel, R.A.4    Parkinson, J.F.5    Perez, D.H.6    Steinman, L.7
  • 3
    • 0030560858 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis
    • Cross A.H., Keeling R.M., Goorha S., San M., Rodi C., Wyatt P.S., Manning P.T., and Misko T.P. Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis. J. Neuroimmunol. 71 (1996) 145-153
    • (1996) J. Neuroimmunol. , vol.71 , pp. 145-153
    • Cross, A.H.1    Keeling, R.M.2    Goorha, S.3    San, M.4    Rodi, C.5    Wyatt, P.S.6    Manning, P.T.7    Misko, T.P.8
  • 4
    • 0028360840 scopus 로고
    • Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice
    • Cross A.H., Misko T.P., Lin R.F., Hickey W.F., Trotter J.L., and Tilton R.G. Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice. J. Clin. Invest. 93 (1994) 2684-2690
    • (1994) J. Clin. Invest. , vol.93 , pp. 2684-2690
    • Cross, A.H.1    Misko, T.P.2    Lin, R.F.3    Hickey, W.F.4    Trotter, J.L.5    Tilton, R.G.6
  • 5
    • 33644963786 scopus 로고    scopus 로고
    • NOS2 regulates cytokine production and VLA-4 expression in experimental autoimmune encephalomyelitis
    • Cross A.H., Ramsbottom M.J., and Lyons J.A. NOS2 regulates cytokine production and VLA-4 expression in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 173 (2006) 79-86
    • (2006) J. Neuroimmunol. , vol.173 , pp. 79-86
    • Cross, A.H.1    Ramsbottom, M.J.2    Lyons, J.A.3
  • 12
    • 0028868821 scopus 로고
    • Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis
    • Okuda Y., Nakatsuji Y., Fujimura H., Esumi H., Ogura T., Yanagihara T., and Sakoda S. Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis. J. Neuroimmunol. 62 (1995) 103-112
    • (1995) J. Neuroimmunol. , vol.62 , pp. 103-112
    • Okuda, Y.1    Nakatsuji, Y.2    Fujimura, H.3    Esumi, H.4    Ogura, T.5    Yanagihara, T.6    Sakoda, S.7
  • 13
    • 0036024613 scopus 로고    scopus 로고
    • Genetic background determines sensitivity to the inhibitory function of NO on T cell proliferation and the amounts of NO production mediated through IFN-gamma
    • Ozaki A., Fukushima A., Fukata K., Sakamoto S., Taniguchi T., Hashiguch M., and Ueno H. Genetic background determines sensitivity to the inhibitory function of NO on T cell proliferation and the amounts of NO production mediated through IFN-gamma. Microbiol. Immunol. 46 (2002) 555-563
    • (2002) Microbiol. Immunol. , vol.46 , pp. 555-563
    • Ozaki, A.1    Fukushima, A.2    Fukata, K.3    Sakamoto, S.4    Taniguchi, T.5    Hashiguch, M.6    Ueno, H.7
  • 14
    • 0031960227 scopus 로고    scopus 로고
    • Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis
    • Sahrbacher U.C., Lechner F., Eugster H.P., Frei K., Lassmann H., and Fontana A. Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis. Eur. J. Immunol. 28 (1998) 1332-1338
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1332-1338
    • Sahrbacher, U.C.1    Lechner, F.2    Eugster, H.P.3    Frei, K.4    Lassmann, H.5    Fontana, A.6
  • 15
    • 12044249483 scopus 로고
    • IL-12: initiation cytokine for cell-mediated immunity
    • Scott P. IL-12: initiation cytokine for cell-mediated immunity. Science 260 (1993) 496-497
    • (1993) Science , vol.260 , pp. 496-497
    • Scott, P.1
  • 16
    • 0027156812 scopus 로고
    • Selective differentiation of CD4+ T helper cell subsets
    • Scott P. Selective differentiation of CD4+ T helper cell subsets. Curr. Opin. Immunol. 5 (1993) 391-397
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 391-397
    • Scott, P.1
  • 17
    • 0038243261 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis: cytokines, effector T cells, and antigen-presenting cells in a prototypical Th1-mediated autoimmune disease
    • Segal B.M. Experimental autoimmune encephalomyelitis: cytokines, effector T cells, and antigen-presenting cells in a prototypical Th1-mediated autoimmune disease. Curr. Allergy Asthma Rep. 3 (2003) 86-93
    • (2003) Curr. Allergy Asthma Rep. , vol.3 , pp. 86-93
    • Segal, B.M.1
  • 18
    • 0032536447 scopus 로고    scopus 로고
    • An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
    • Segal B.M., Dwyer B.K., and Shevach E.M. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J. Exp. Med. 187 (1998) 537-546
    • (1998) J. Exp. Med. , vol.187 , pp. 537-546
    • Segal, B.M.1    Dwyer, B.K.2    Shevach, E.M.3
  • 19
    • 0029788704 scopus 로고    scopus 로고
    • IL-12 unmasks latent autoimmune disease in resistant mice
    • Segal B.M., and Shevach E.M. IL-12 unmasks latent autoimmune disease in resistant mice. J. Exp. Med. 184 (1996) 771-775
    • (1996) J. Exp. Med. , vol.184 , pp. 771-775
    • Segal, B.M.1    Shevach, E.M.2
  • 20
    • 24744470740 scopus 로고    scopus 로고
    • Experimental models of relapsing-remitting multiple sclerosis: current concepts and perspective
    • Skundric D.S. Experimental models of relapsing-remitting multiple sclerosis: current concepts and perspective. Curr. Neurovasc. Res. 2 (2005) 349-362
    • (2005) Curr. Neurovasc. Res. , vol.2 , pp. 349-362
    • Skundric, D.S.1
  • 21
    • 0038265435 scopus 로고    scopus 로고
    • Nitric oxide induces polarization of actin in encephalitogenic T cells and inhibits their in vitro trans-endothelial migration in a p70S6 kinase-independent manner
    • Staykova M.A., Berven L.A., Cowden W.B., Willenborg D.O., and Crouch M.F. Nitric oxide induces polarization of actin in encephalitogenic T cells and inhibits their in vitro trans-endothelial migration in a p70S6 kinase-independent manner. FASEB J. 17 (2003) 1337-1339
    • (2003) FASEB J. , vol.17 , pp. 1337-1339
    • Staykova, M.A.1    Berven, L.A.2    Cowden, W.B.3    Willenborg, D.O.4    Crouch, M.F.5
  • 22
    • 33644545052 scopus 로고    scopus 로고
    • Nitric oxide inhibits T cell adhesion and migration by down-regulation of beta1-integrin expression in immunologically liver-injured mice
    • Sun Y., Liu J., Qian F., and Xu Q. Nitric oxide inhibits T cell adhesion and migration by down-regulation of beta1-integrin expression in immunologically liver-injured mice. Int. Immunopharmacol. 6 (2006) 616-626
    • (2006) Int. Immunopharmacol. , vol.6 , pp. 616-626
    • Sun, Y.1    Liu, J.2    Qian, F.3    Xu, Q.4
  • 23
    • 0030942911 scopus 로고    scopus 로고
    • Inhibition of IL-2 production by nitric oxide: a novel self-regulatory mechanism for Th1 cell proliferation
    • Taylor-Robinson A.W. Inhibition of IL-2 production by nitric oxide: a novel self-regulatory mechanism for Th1 cell proliferation. Immunol. Cell Biol. 75 (1997) 167-175
    • (1997) Immunol. Cell Biol. , vol.75 , pp. 167-175
    • Taylor-Robinson, A.W.1
  • 25
    • 0033120962 scopus 로고    scopus 로고
    • Mice with IFN-gamma receptor deficiency are less susceptible to experimental autoimmune myasthenia gravis
    • Zhang G.X., Xiao B.G., Bai X.F., van M.P., Orn A., and Link H. Mice with IFN-gamma receptor deficiency are less susceptible to experimental autoimmune myasthenia gravis. J. Immunol. 162 (1999) 3775-3781
    • (1999) J. Immunol. , vol.162 , pp. 3775-3781
    • Zhang, G.X.1    Xiao, B.G.2    Bai, X.F.3    van, M.P.4    Orn, A.5    Link, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.