-
1
-
-
33749027200
-
Long-term subcutaneous interferon beta-1a therapy in patients with relapsing-remitting MS
-
Kappos L, Traboulsee A, Constantinescu C, Eralinna JP, Forrestal F, Jongen P, Pollard J, Sandberg-Wollheim M, Sindic C, Stubinski B, Uitdehaag B, Li D. Long-term subcutaneous interferon beta-1a therapy in patients with relapsing-remitting MS. Neurology 2006;67:944-953.
-
(2006)
Neurology
, vol.67
, pp. 944-953
-
-
Kappos, L.1
Traboulsee, A.2
Constantinescu, C.3
Eralinna, J.P.4
Forrestal, F.5
Jongen, P.6
Pollard, J.7
Sandberg-Wollheim, M.8
Sindic, C.9
Stubinski, B.10
Uitdehaag, B.11
Li, D.12
-
2
-
-
17644396349
-
Immunology of multiple sclerosis [Review]
-
Sospedra M, Martin R. Immunology of multiple sclerosis [Review]. Annu. Rev. Immunol. 2005;23:683-747.
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
4
-
-
0032522488
-
CTLA-4 regulates tolerance induction and T cell differentiation in vivo
-
Walunas TL, Bluestone JA. CTLA-4 regulates tolerance induction and T cell differentiation in vivo. J. Immunol. 1998;160:3855-3860.
-
(1998)
J. Immunol
, vol.160
, pp. 3855-3860
-
-
Walunas, T.L.1
Bluestone, J.A.2
-
5
-
-
0028870051
-
CTLA4 mediates antigen-specific apoptosis of human T cells
-
Gribben JG, Freeman GJ, Boussiotis VA, Rennert P, Jellis CL, Greenfield E, Barber M, Restivo VA Jr, Ke X, Gray GS, Nadler LM. CTLA4 mediates antigen-specific apoptosis of human T cells. Proc. Natl. Acad. Sci. USA 1995;92:811-815.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 811-815
-
-
Gribben, J.G.1
Freeman, G.J.2
Boussiotis, V.A.3
Rennert, P.4
Jellis, C.L.5
Greenfield, E.6
Barber, M.7
Restivo Jr, V.A.8
Ke, X.9
Gray, G.S.10
Nadler, L.M.11
-
6
-
-
33845385221
-
The role of Foxp3+ regulatory T cells in liver transplant tolerance
-
Li W, Carper K, Zheng XX, Kuhr CS, Reyes JD, Liang Y, Perkins DL, Thomson AW, Perkins JD. The role of Foxp3+ regulatory T cells in liver transplant tolerance. Transplant. Proc. 2006;38:3205-3206.
-
(2006)
Transplant. Proc
, vol.38
, pp. 3205-3206
-
-
Li, W.1
Carper, K.2
Zheng, X.X.3
Kuhr, C.S.4
Reyes, J.D.5
Liang, Y.6
Perkins, D.L.7
Thomson, A.W.8
Perkins, J.D.9
-
7
-
-
0026706261
-
Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen
-
Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, et al. Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J. Biol. Chem. 1992;267:10709-10715.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 10709-10715
-
-
Oehm, A.1
Behrmann, I.2
Falk, W.3
Pawlita, M.4
Maier, G.5
Klas, C.6
Li-Weber, M.7
Richards, S.8
Dhein, J.9
Trauth, B.C.10
-
8
-
-
0027145632
-
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
-
Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993;75:1169-1178.
-
(1993)
Cell
, vol.75
, pp. 1169-1178
-
-
Suda, T.1
Takahashi, T.2
Golstein, P.3
Nagata, S.4
-
9
-
-
0027314703
-
Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
-
Russell JH, Rush B, Weaver C, Wang R. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 1993;90:4409-4413.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4409-4413
-
-
Russell, J.H.1
Rush, B.2
Weaver, C.3
Wang, R.4
-
10
-
-
0027284016
-
Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells
-
Russell JH, Wang R. Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells. Eur. J. Immunol. 1993;23:2379-2382.
-
(1993)
Eur. J. Immunol
, vol.23
, pp. 2379-2382
-
-
Russell, J.H.1
Wang, R.2
-
11
-
-
0029960673
-
Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain
-
Dowling P, Shang G, Raval S, Menonna J, Cook S, Husar W. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J. Exp. Med. 1996;184:1513-1518.
-
(1996)
J. Exp. Med
, vol.184
, pp. 1513-1518
-
-
Dowling, P.1
Shang, G.2
Raval, S.3
Menonna, J.4
Cook, S.5
Husar, W.6
-
12
-
-
0031715518
-
T-cell apoptosis in inflammatory brain lesions: Destruction of T cells does not depend on antigen recognition
-
Bauer J, Bradl M, Hickley WF, Forss-Petter S, Breitschopf H, Linington C, Wekerle H, Lassmann H. T-cell apoptosis in inflammatory brain lesions: destruction of T cells does not depend on antigen recognition. Am. J. Pathol. 1998;153:715-724.
-
(1998)
Am. J. Pathol
, vol.153
, pp. 715-724
-
-
Bauer, J.1
Bradl, M.2
Hickley, W.F.3
Forss-Petter, S.4
Breitschopf, H.5
Linington, C.6
Wekerle, H.7
Lassmann, H.8
-
13
-
-
33846847853
-
Antigen therapy of experimental autoimmune encephalomyelitis selectively induces apoptosis of pathogenic T cells
-
Tischner D, Weishaupt A, van den Brandt J, Ip CW, Kerkau T, Gold R, Reichardt HM. Antigen therapy of experimental autoimmune encephalomyelitis selectively induces apoptosis of pathogenic T cells. J. Neuroimmunol. 2007;183:146-150.
-
(2007)
J. Neuroimmunol
, vol.183
, pp. 146-150
-
-
Tischner, D.1
Weishaupt, A.2
van den Brandt, J.3
Ip, C.W.4
Kerkau, T.5
Gold, R.6
Reichardt, H.M.7
-
14
-
-
33846295564
-
Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years
-
Lopatinskaya L, Zwemmer J, Uitdehaag B, Lucas K, Polman C, Nagelkerken L. Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years. Mult. Scler. 2006;12:704-709.
-
(2006)
Mult. Scler
, vol.12
, pp. 704-709
-
-
Lopatinskaya, L.1
Zwemmer, J.2
Uitdehaag, B.3
Lucas, K.4
Polman, C.5
Nagelkerken, L.6
-
15
-
-
0036147325
-
Disease activity in multiple sclerosis correlates with T lymphocyte expression of the inhibitor of apoptosis proteins
-
Semra YK, Seidi OA, Sharief MK. Disease activity in multiple sclerosis correlates with T lymphocyte expression of the inhibitor of apoptosis proteins. J. Neuroimmunol. 2002;122:159-166.
-
(2002)
J. Neuroimmunol
, vol.122
, pp. 159-166
-
-
Semra, Y.K.1
Seidi, O.A.2
Sharief, M.K.3
-
17
-
-
0020686503
-
New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
-
Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberberg DH, Tourtellotte WW. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 1983;13:227-231.
-
(1983)
Ann. Neurol
, vol.13
, pp. 227-231
-
-
Poser, C.M.1
Paty, D.W.2
Scheinberg, L.3
McDonald, W.I.4
Davis, F.A.5
Ebers, G.C.6
Johnson, K.P.7
Sibley, W.A.8
Silberberg, D.H.9
Tourtellotte, W.W.10
-
18
-
-
0015264390
-
Large-scale preparation of myelin basic protein from central nervous tissue of several mammalian species
-
Deibler GE, Martenson RE, Kies MW. Large-scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep. Biochem. 1972;2:139-165.
-
(1972)
Prep. Biochem
, vol.2
, pp. 139-165
-
-
Deibler, G.E.1
Martenson, R.E.2
Kies, M.W.3
-
19
-
-
0019760184
-
Biochemistry of myelin
-
Norton WT. Biochemistry of myelin. Adv. Neurol. 1981;31:93-121.
-
(1981)
Adv. Neurol
, vol.31
, pp. 93-121
-
-
Norton, W.T.1
-
20
-
-
0015857284
-
Myelination in rat brain: Method of myelin isolation
-
Norton WT, Poduslo SE. Myelination in rat brain: method of myelin isolation. J. Neurochem. 1973;21:749-757.
-
(1973)
J. Neurochem
, vol.21
, pp. 749-757
-
-
Norton, W.T.1
Poduslo, S.E.2
-
21
-
-
0025370870
-
T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
-
Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990;346:183-187.
-
(1990)
Nature
, vol.346
, pp. 183-187
-
-
Ota, K.1
Matsui, M.2
Milford, E.L.3
Mackin, G.A.4
Weiner, H.L.5
Hafler, D.A.6
-
22
-
-
0024596885
-
MS: A CNS and systemic autoimmune disease
-
Hafler DA, Weiner HL. MS: a CNS and systemic autoimmune disease. Immunol. Today 1989;10:104-107.
-
(1989)
Immunol. Today
, vol.10
, pp. 104-107
-
-
Hafler, D.A.1
Weiner, H.L.2
-
23
-
-
0038544597
-
Costimulatory molecule expression on leukocytes from mice with experimental autoimmune encephalomyelitis treated with IFN-β
-
Hallal DE, Farias AS, Oliveira EC, Diaz-Bardales BM, Brandao CO, Protti GG, Pereira FG, Metze IL, Santos LM. Costimulatory molecule expression on leukocytes from mice with experimental autoimmune encephalomyelitis treated with IFN-β. Interferon Cytokine Res. 2003;23:293-298.
-
(2003)
Interferon Cytokine Res
, vol.23
, pp. 293-298
-
-
Hallal, D.E.1
Farias, A.S.2
Oliveira, E.C.3
Diaz-Bardales, B.M.4
Brandao, C.O.5
Protti, G.G.6
Pereira, F.G.7
Metze, I.L.8
Santos, L.M.9
-
24
-
-
0036890956
-
Baseline T cell reactivity in multiple sclerosis is correlated to efficacy of interferon-beta
-
Killestein J, Hintzen RQ, Uitdehaag BM, Baars PA, Roos MT, van Lier RA, Polman CH. Baseline T cell reactivity in multiple sclerosis is correlated to efficacy of interferon-beta. J. Neuroimmunol. 2002;133:217-224.
-
(2002)
J. Neuroimmunol
, vol.133
, pp. 217-224
-
-
Killestein, J.1
Hintzen, R.Q.2
Uitdehaag, B.M.3
Baars, P.A.4
Roos, M.T.5
van Lier, R.A.6
Polman, C.H.7
-
25
-
-
33748479268
-
IFN-beta inhibits T cell activation capacity of central nervous system APCs
-
Teige I, Liu Y, Issazadeh-Navikas S. IFN-beta inhibits T cell activation capacity of central nervous system APCs. J. Immunol. 2006;177:3542-3553.
-
(2006)
J. Immunol
, vol.177
, pp. 3542-3553
-
-
Teige, I.1
Liu, Y.2
Issazadeh-Navikas, S.3
-
26
-
-
33646816017
-
Altered maturation of circulating dendritic cells in primary progressive MS patients
-
Lopez C, Comabella M, Al-zayat H, Tintore M, Montalban X. Altered maturation of circulating dendritic cells in primary progressive MS patients. J. Neuroimmunol. 2006;175:183-191.
-
(2006)
J. Neuroimmunol
, vol.175
, pp. 183-191
-
-
Lopez, C.1
Comabella, M.2
Al-zayat, H.3
Tintore, M.4
Montalban, X.5
-
27
-
-
0037377237
-
-
Gniadek P, Aktas O, Wandinger KP, Bellmann-Strobl J, Wengert O, Weber A, von WussowP, Obert HJ, Zipp F. Systemic IFN-beta treatment induces apoptosis of peripheral immune cells in MS patients. J. Neuroimmunol. 2003;137:187-196.
-
Gniadek P, Aktas O, Wandinger KP, Bellmann-Strobl J, Wengert O, Weber A, von WussowP, Obert HJ, Zipp F. Systemic IFN-beta treatment induces apoptosis of peripheral immune cells in MS patients. J. Neuroimmunol. 2003;137:187-196.
-
-
-
-
28
-
-
0037022617
-
Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice
-
Hurwitz AA, Sullivan TJ, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice. Proc. Natl. Acad. Sci. USA 2002;99:3013-3017.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3013-3017
-
-
Hurwitz, A.A.1
Sullivan, T.J.2
Sobel, R.A.3
Allison, J.P.4
-
29
-
-
0034703310
-
CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis
-
Karandikar NJ, Eagar TN, Vanderlugt CL, Bluestone JA, Miller SD. CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2000;109:173-180.
-
(2000)
J. Neuroimmunol
, vol.109
, pp. 173-180
-
-
Karandikar, N.J.1
Eagar, T.N.2
Vanderlugt, C.L.3
Bluestone, J.A.4
Miller, S.D.5
-
30
-
-
0030176371
-
Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
-
Linsley PS, Bradshaw J, Greene J, Peach R, Bennett KL, Mittler RS. Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement. Immunity 1996;4:535-543.
-
(1996)
Immunity
, vol.4
, pp. 535-543
-
-
Linsley, P.S.1
Bradshaw, J.2
Greene, J.3
Peach, R.4
Bennett, K.L.5
Mittler, R.S.6
-
31
-
-
0030966217
-
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement
-
Perez VL, Van Parijs L, Biuckians A, Zheng XX, Strom TB, Abbas AK. Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity 1997;6:411-417.
-
(1997)
Immunity
, vol.6
, pp. 411-417
-
-
Perez, V.L.1
Van Parijs, L.2
Biuckians, A.3
Zheng, X.X.4
Strom, T.B.5
Abbas, A.K.6
-
32
-
-
0035292756
-
The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T function
-
Coyle AJ, Gutierrez-Ramos JC. The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T function. Nat. Immunol. 2001;2:203-209.
-
(2001)
Nat. Immunol
, vol.2
, pp. 203-209
-
-
Coyle, A.J.1
Gutierrez-Ramos, J.C.2
-
33
-
-
2442461055
-
The roles of the new negative T cell costimulatory pathways in regulating autoimmunity [Review]
-
Khoury SJ, Sayegh MH. The roles of the new negative T cell costimulatory pathways in regulating autoimmunity [Review]. Immunity 2004;20:529-38.
-
(2004)
Immunity
, vol.20
, pp. 529-538
-
-
Khoury, S.J.1
Sayegh, M.H.2
-
34
-
-
0032538819
-
Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells
-
Chen W, Jin W, Wahl SM. Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells. J. Exp. Med. 1998;188:1849-1857.
-
(1998)
J. Exp. Med
, vol.188
, pp. 1849-1857
-
-
Chen, W.1
Jin, W.2
Wahl, S.M.3
-
35
-
-
33746933828
-
TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling
-
Oida T, Xu L, Weiner HL, Kitani A, Strober W. TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling. J. Immunol. 2006;177:2331-2319.
-
(2006)
J. Immunol
, vol.177
, pp. 2331-2319
-
-
Oida, T.1
Xu, L.2
Weiner, H.L.3
Kitani, A.4
Strober, W.5
-
36
-
-
33644835247
-
TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells
-
Zheng SG, Wang JH, Stohl W, Kim KS, Gray JD, Horwitz DA.TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells. J. Immunol. 2006;176:3321-3329.
-
(2006)
J. Immunol
, vol.176
, pp. 3321-3329
-
-
Zheng, S.G.1
Wang, J.H.2
Stohl, W.3
Kim, K.S.4
Gray, J.D.5
Horwitz, D.A.6
-
37
-
-
0032543987
-
Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 crosslinking
-
Scheipers P, Reiser H. Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 crosslinking. Proc. Natl. Acad. Sci. USA 1998;95:10083-10088.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10083-10088
-
-
Scheipers, P.1
Reiser, H.2
-
38
-
-
0034633768
-
Defective T cell Fas function in patients with multiple sclerosis
-
Comi C, Leone M, Bonissoni S, DeFranco S, Bottarel F, Mezzatesta C, Chiocchetti A, Perla F, Monaco F, Dianzani U. Defective T cell Fas function in patients with multiple sclerosis. Neurology 2000;55:921-997.
-
(2000)
Neurology
, vol.55
, pp. 921-997
-
-
Comi, C.1
Leone, M.2
Bonissoni, S.3
DeFranco, S.4
Bottarel, F.5
Mezzatesta, C.6
Chiocchetti, A.7
Perla, F.8
Monaco, F.9
Dianzani, U.10
-
39
-
-
29244464322
-
Apoptosis of T cells in peripheral blood and cerebrospinal fluid is associated with disease activity of multiple sclerosis
-
Okuda Y, Apatoff BR, Posnett DN. Apoptosis of T cells in peripheral blood and cerebrospinal fluid is associated with disease activity of multiple sclerosis. J. Neuroimmunol. 2006;171:163-170.
-
(2006)
J. Neuroimmunol
, vol.171
, pp. 163-170
-
-
Okuda, Y.1
Apatoff, B.R.2
Posnett, D.N.3
-
40
-
-
33846295564
-
Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years
-
Lopatinskaya L, Zwemmer J, Uitdehaag B, Lucas K, Polman C, Nagelkerken L. Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years. Mult. Scler. 2006;12:704-709.
-
(2006)
Mult. Scler
, vol.12
, pp. 704-709
-
-
Lopatinskaya, L.1
Zwemmer, J.2
Uitdehaag, B.3
Lucas, K.4
Polman, C.5
Nagelkerken, L.6
-
41
-
-
0036344715
-
Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy
-
Sharief MK, Noori MA, Zoukos Y. Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy. J. Neuroimmunol. 2002;129:224-231.
-
(2002)
J. Neuroimmunol
, vol.129
, pp. 224-231
-
-
Sharief, M.K.1
Noori, M.A.2
Zoukos, Y.3
-
42
-
-
0031915404
-
Increased serum levels of soluble CD95 (APO-1/Fas) in relapsing-remitting multiple sclerosis
-
Zipp F, Weller M, Calabresi PA, Frank JA, Bash CN, Dichgans J, McFarland HF, Martin R. Increased serum levels of soluble CD95 (APO-1/Fas) in relapsing-remitting multiple sclerosis. Ann. Neurol. 1998;43:116-120.
-
(1998)
Ann. Neurol
, vol.43
, pp. 116-120
-
-
Zipp, F.1
Weller, M.2
Calabresi, P.A.3
Frank, J.A.4
Bash, C.N.5
Dichgans, J.6
McFarland, H.F.7
Martin, R.8
-
43
-
-
0028274042
-
Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule
-
Cheng J, Zhou T, Liu C, Shapiro JP, Brauer MJ, Kiefer MC, Barr PJ, Mountz JD. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 1994;263:1759-1762.
-
(1994)
Science
, vol.263
, pp. 1759-1762
-
-
Cheng, J.1
Zhou, T.2
Liu, C.3
Shapiro, J.P.4
Brauer, M.J.5
Kiefer, M.C.6
Barr, P.J.7
Mountz, J.D.8
-
44
-
-
0032525797
-
Serum CD95 of relapsing remitting multiple sclerosis patients protects from CD95-mediated apoptosis
-
Zipp F, Otzelberger K, Dichgans J, Martin R, Weller M. Serum CD95 of relapsing remitting multiple sclerosis patients protects from CD95-mediated apoptosis. J. Neuroimmunol. 1998;86:151-154.
-
(1998)
J. Neuroimmunol
, vol.86
, pp. 151-154
-
-
Zipp, F.1
Otzelberger, K.2
Dichgans, J.3
Martin, R.4
Weller, M.5
|