메뉴 건너뛰기




Volumn 27, Issue 10, 2007, Pages 865-873

Diminished myelin-specific T cell activation associated with increase in CTLA4 and Fas molecules in multiple sclerosis patients treated with IFN-β

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FAS ANTIGEN; INTERFERON BETA SERINE; MYELIN; MYELIN BASIC PROTEIN;

EID: 35648938148     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.2007.0018     Document Type: Article
Times cited : (24)

References (44)
  • 2
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis [Review]
    • Sospedra M, Martin R. Immunology of multiple sclerosis [Review]. Annu. Rev. Immunol. 2005;23:683-747.
    • (2005) Annu. Rev. Immunol , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 4
    • 0032522488 scopus 로고    scopus 로고
    • CTLA-4 regulates tolerance induction and T cell differentiation in vivo
    • Walunas TL, Bluestone JA. CTLA-4 regulates tolerance induction and T cell differentiation in vivo. J. Immunol. 1998;160:3855-3860.
    • (1998) J. Immunol , vol.160 , pp. 3855-3860
    • Walunas, T.L.1    Bluestone, J.A.2
  • 7
    • 0026706261 scopus 로고
    • Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen
    • Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, et al. Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J. Biol. Chem. 1992;267:10709-10715.
    • (1992) J. Biol. Chem , vol.267 , pp. 10709-10715
    • Oehm, A.1    Behrmann, I.2    Falk, W.3    Pawlita, M.4    Maier, G.5    Klas, C.6    Li-Weber, M.7    Richards, S.8    Dhein, J.9    Trauth, B.C.10
  • 8
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993;75:1169-1178.
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 9
    • 0027314703 scopus 로고
    • Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
    • Russell JH, Rush B, Weaver C, Wang R. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 1993;90:4409-4413.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4409-4413
    • Russell, J.H.1    Rush, B.2    Weaver, C.3    Wang, R.4
  • 10
    • 0027284016 scopus 로고
    • Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells
    • Russell JH, Wang R. Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells. Eur. J. Immunol. 1993;23:2379-2382.
    • (1993) Eur. J. Immunol , vol.23 , pp. 2379-2382
    • Russell, J.H.1    Wang, R.2
  • 11
    • 0029960673 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain
    • Dowling P, Shang G, Raval S, Menonna J, Cook S, Husar W. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J. Exp. Med. 1996;184:1513-1518.
    • (1996) J. Exp. Med , vol.184 , pp. 1513-1518
    • Dowling, P.1    Shang, G.2    Raval, S.3    Menonna, J.4    Cook, S.5    Husar, W.6
  • 13
  • 14
    • 33846295564 scopus 로고    scopus 로고
    • Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years
    • Lopatinskaya L, Zwemmer J, Uitdehaag B, Lucas K, Polman C, Nagelkerken L. Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years. Mult. Scler. 2006;12:704-709.
    • (2006) Mult. Scler , vol.12 , pp. 704-709
    • Lopatinskaya, L.1    Zwemmer, J.2    Uitdehaag, B.3    Lucas, K.4    Polman, C.5    Nagelkerken, L.6
  • 15
    • 0036147325 scopus 로고    scopus 로고
    • Disease activity in multiple sclerosis correlates with T lymphocyte expression of the inhibitor of apoptosis proteins
    • Semra YK, Seidi OA, Sharief MK. Disease activity in multiple sclerosis correlates with T lymphocyte expression of the inhibitor of apoptosis proteins. J. Neuroimmunol. 2002;122:159-166.
    • (2002) J. Neuroimmunol , vol.122 , pp. 159-166
    • Semra, Y.K.1    Seidi, O.A.2    Sharief, M.K.3
  • 18
    • 0015264390 scopus 로고
    • Large-scale preparation of myelin basic protein from central nervous tissue of several mammalian species
    • Deibler GE, Martenson RE, Kies MW. Large-scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep. Biochem. 1972;2:139-165.
    • (1972) Prep. Biochem , vol.2 , pp. 139-165
    • Deibler, G.E.1    Martenson, R.E.2    Kies, M.W.3
  • 19
    • 0019760184 scopus 로고
    • Biochemistry of myelin
    • Norton WT. Biochemistry of myelin. Adv. Neurol. 1981;31:93-121.
    • (1981) Adv. Neurol , vol.31 , pp. 93-121
    • Norton, W.T.1
  • 20
    • 0015857284 scopus 로고
    • Myelination in rat brain: Method of myelin isolation
    • Norton WT, Poduslo SE. Myelination in rat brain: method of myelin isolation. J. Neurochem. 1973;21:749-757.
    • (1973) J. Neurochem , vol.21 , pp. 749-757
    • Norton, W.T.1    Poduslo, S.E.2
  • 21
    • 0025370870 scopus 로고
    • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
    • Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990;346:183-187.
    • (1990) Nature , vol.346 , pp. 183-187
    • Ota, K.1    Matsui, M.2    Milford, E.L.3    Mackin, G.A.4    Weiner, H.L.5    Hafler, D.A.6
  • 22
    • 0024596885 scopus 로고
    • MS: A CNS and systemic autoimmune disease
    • Hafler DA, Weiner HL. MS: a CNS and systemic autoimmune disease. Immunol. Today 1989;10:104-107.
    • (1989) Immunol. Today , vol.10 , pp. 104-107
    • Hafler, D.A.1    Weiner, H.L.2
  • 25
    • 33748479268 scopus 로고    scopus 로고
    • IFN-beta inhibits T cell activation capacity of central nervous system APCs
    • Teige I, Liu Y, Issazadeh-Navikas S. IFN-beta inhibits T cell activation capacity of central nervous system APCs. J. Immunol. 2006;177:3542-3553.
    • (2006) J. Immunol , vol.177 , pp. 3542-3553
    • Teige, I.1    Liu, Y.2    Issazadeh-Navikas, S.3
  • 26
    • 33646816017 scopus 로고    scopus 로고
    • Altered maturation of circulating dendritic cells in primary progressive MS patients
    • Lopez C, Comabella M, Al-zayat H, Tintore M, Montalban X. Altered maturation of circulating dendritic cells in primary progressive MS patients. J. Neuroimmunol. 2006;175:183-191.
    • (2006) J. Neuroimmunol , vol.175 , pp. 183-191
    • Lopez, C.1    Comabella, M.2    Al-zayat, H.3    Tintore, M.4    Montalban, X.5
  • 27
    • 0037377237 scopus 로고    scopus 로고
    • Gniadek P, Aktas O, Wandinger KP, Bellmann-Strobl J, Wengert O, Weber A, von WussowP, Obert HJ, Zipp F. Systemic IFN-beta treatment induces apoptosis of peripheral immune cells in MS patients. J. Neuroimmunol. 2003;137:187-196.
    • Gniadek P, Aktas O, Wandinger KP, Bellmann-Strobl J, Wengert O, Weber A, von WussowP, Obert HJ, Zipp F. Systemic IFN-beta treatment induces apoptosis of peripheral immune cells in MS patients. J. Neuroimmunol. 2003;137:187-196.
  • 28
    • 0037022617 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice
    • Hurwitz AA, Sullivan TJ, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice. Proc. Natl. Acad. Sci. USA 2002;99:3013-3017.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3013-3017
    • Hurwitz, A.A.1    Sullivan, T.J.2    Sobel, R.A.3    Allison, J.P.4
  • 29
    • 0034703310 scopus 로고    scopus 로고
    • CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis
    • Karandikar NJ, Eagar TN, Vanderlugt CL, Bluestone JA, Miller SD. CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2000;109:173-180.
    • (2000) J. Neuroimmunol , vol.109 , pp. 173-180
    • Karandikar, N.J.1    Eagar, T.N.2    Vanderlugt, C.L.3    Bluestone, J.A.4    Miller, S.D.5
  • 30
    • 0030176371 scopus 로고    scopus 로고
    • Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
    • Linsley PS, Bradshaw J, Greene J, Peach R, Bennett KL, Mittler RS. Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement. Immunity 1996;4:535-543.
    • (1996) Immunity , vol.4 , pp. 535-543
    • Linsley, P.S.1    Bradshaw, J.2    Greene, J.3    Peach, R.4    Bennett, K.L.5    Mittler, R.S.6
  • 32
    • 0035292756 scopus 로고    scopus 로고
    • The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T function
    • Coyle AJ, Gutierrez-Ramos JC. The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T function. Nat. Immunol. 2001;2:203-209.
    • (2001) Nat. Immunol , vol.2 , pp. 203-209
    • Coyle, A.J.1    Gutierrez-Ramos, J.C.2
  • 33
    • 2442461055 scopus 로고    scopus 로고
    • The roles of the new negative T cell costimulatory pathways in regulating autoimmunity [Review]
    • Khoury SJ, Sayegh MH. The roles of the new negative T cell costimulatory pathways in regulating autoimmunity [Review]. Immunity 2004;20:529-38.
    • (2004) Immunity , vol.20 , pp. 529-538
    • Khoury, S.J.1    Sayegh, M.H.2
  • 34
    • 0032538819 scopus 로고    scopus 로고
    • Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells
    • Chen W, Jin W, Wahl SM. Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells. J. Exp. Med. 1998;188:1849-1857.
    • (1998) J. Exp. Med , vol.188 , pp. 1849-1857
    • Chen, W.1    Jin, W.2    Wahl, S.M.3
  • 35
    • 33746933828 scopus 로고    scopus 로고
    • TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling
    • Oida T, Xu L, Weiner HL, Kitani A, Strober W. TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling. J. Immunol. 2006;177:2331-2319.
    • (2006) J. Immunol , vol.177 , pp. 2331-2319
    • Oida, T.1    Xu, L.2    Weiner, H.L.3    Kitani, A.4    Strober, W.5
  • 36
    • 33644835247 scopus 로고    scopus 로고
    • TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells
    • Zheng SG, Wang JH, Stohl W, Kim KS, Gray JD, Horwitz DA.TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells. J. Immunol. 2006;176:3321-3329.
    • (2006) J. Immunol , vol.176 , pp. 3321-3329
    • Zheng, S.G.1    Wang, J.H.2    Stohl, W.3    Kim, K.S.4    Gray, J.D.5    Horwitz, D.A.6
  • 37
    • 0032543987 scopus 로고    scopus 로고
    • Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 crosslinking
    • Scheipers P, Reiser H. Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 crosslinking. Proc. Natl. Acad. Sci. USA 1998;95:10083-10088.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10083-10088
    • Scheipers, P.1    Reiser, H.2
  • 39
    • 29244464322 scopus 로고    scopus 로고
    • Apoptosis of T cells in peripheral blood and cerebrospinal fluid is associated with disease activity of multiple sclerosis
    • Okuda Y, Apatoff BR, Posnett DN. Apoptosis of T cells in peripheral blood and cerebrospinal fluid is associated with disease activity of multiple sclerosis. J. Neuroimmunol. 2006;171:163-170.
    • (2006) J. Neuroimmunol , vol.171 , pp. 163-170
    • Okuda, Y.1    Apatoff, B.R.2    Posnett, D.N.3
  • 40
    • 33846295564 scopus 로고    scopus 로고
    • Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years
    • Lopatinskaya L, Zwemmer J, Uitdehaag B, Lucas K, Polman C, Nagelkerken L. Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years. Mult. Scler. 2006;12:704-709.
    • (2006) Mult. Scler , vol.12 , pp. 704-709
    • Lopatinskaya, L.1    Zwemmer, J.2    Uitdehaag, B.3    Lucas, K.4    Polman, C.5    Nagelkerken, L.6
  • 41
    • 0036344715 scopus 로고    scopus 로고
    • Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy
    • Sharief MK, Noori MA, Zoukos Y. Reduced expression of the inhibitor of apoptosis proteins in T cells from patients with multiple sclerosis following interferon-beta therapy. J. Neuroimmunol. 2002;129:224-231.
    • (2002) J. Neuroimmunol , vol.129 , pp. 224-231
    • Sharief, M.K.1    Noori, M.A.2    Zoukos, Y.3
  • 44
    • 0032525797 scopus 로고    scopus 로고
    • Serum CD95 of relapsing remitting multiple sclerosis patients protects from CD95-mediated apoptosis
    • Zipp F, Otzelberger K, Dichgans J, Martin R, Weller M. Serum CD95 of relapsing remitting multiple sclerosis patients protects from CD95-mediated apoptosis. J. Neuroimmunol. 1998;86:151-154.
    • (1998) J. Neuroimmunol , vol.86 , pp. 151-154
    • Zipp, F.1    Otzelberger, K.2    Dichgans, J.3    Martin, R.4    Weller, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.