Metastasis research Society-American Association for Cancer Research joint conference on metastasis

Cancer Research

Volumn 68, Issue 23, 2008, Pages 9578-9582

  Welch, Danny R ^a,b,c,g   Cooper, Carlton R ^c,d   Hurst, Douglas R ^a,c   Lynch, Conor C ^e   Martin, Michelle D ^e   Vaidya, Kedar S ^a,c   Vansaun, Michael N ^e   Mastro, Andrea M ^c,f  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c Department of Pathology   (United States)

^d UNIVERSITY OF DELAWARE   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f PENNSYLVANIA STATE UNIVERSITY   (United States)

^g NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; INITIATION FACTOR 4E; MATRIX METALLOPROTEINASE; MICRORNA; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

CANCER SURVIVAL; CELL TRANSFORMATION; CONFERENCE PAPER; DOWN REGULATION; EDG2 GENE; EPITHELIAL TO MESENCHYMAL TRANSITION; GEMIN5 GENE; GENE; GENE EXPRESSION REGULATION; HUMAN; METASTASIS; METASTASIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; RNA PROCESSING; RNA TRANSLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; HUMANS; NEOPLASM METASTASIS; NEOPLASMS;

EID: 57149096449     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-3360     Document Type: Conference Paper

References (58)

1. Gupta GP, Massagué J. Cancer metastasis: building a framework. Cell 2006;127:679-95.
2. Eccles SA, Welch DR. Metastasis: recent discoveries and novel treatment strategies. Lancet 2007;369:1742-57.
3. Stafford LJ, Vaidya KS, Welch DR. Metastasis suppressors genes in cancer. Int J Biochem Cell Biol 2008;40:874-91.
4. Fingleton B. Molecular targets in metastasis: lessons from genomic approaches. Cancer Genomics Proteomics 2007;4:211-21.
5. Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002;2:442-54.
6. Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 2008;9:102-14.
7. Bushati N, Cohen SM. MicroRNA functions. Annu Rev Cell Dev Biol 2007;23:175-205.
8. Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Genet 2006;6:259-69.
9. Huang QH, Gumireddy K, Schrier M, et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 2008;10:202-10.
10. Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007;449:682-8.
11. Tavazoie SF, Alarcón C, Oskarsson T, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008;451:147-52.
12. Seraj MJ, Samant RS, Verderame MF, Welch DR. Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13. Cancer Res 2000;60:2764-9.
13. Mathonnet G, Fabian MR, Svitkin YV, et al. MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex elF4F. Science 2007;317:1764-7.
14. Mamane Y, Petroulakis E, Rong LW, Yoshida K, Ler LW, Sonenberg N. eIF4E - from translation to transformation. Oncogene 2004;23:3172-9.
15. Graff JR, Konicek BW, Carter JH, Marcusson EG. Targeting the eukaryotic translation initiation factor 4E for cancer therapy. Cancer Res 2008;68:631-4.
16. Graff JR, Konicek BW, Vincent TM, et al. Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity. J Clin Invest 2007;117:2638-48.
17. Lee JH, Horak CE, Khanna C, et al. Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility. Cancer Res 2008;68:639-44.
18. Horak CE, Lee JH, Elkahloun AG, et al. Nm23-1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2. Cancer Res 2007;67:7238-46.
19. Battle DJ, Kasim M, Yong J, et al. The SMN complex: an assembly machine for RNPs. Cold Spring Harb Symp Quant Biol 2006;71:313-20.
20. Witz IP. Yin-yang activities and vicious cycles in the tumor microenvironment. Cancer Res 2008;68:9-13.
21. Manni A, Washington S, Hu X, et al. Effects of polyamine synthesis inhibitors on primary tumor features and metastatic capacity of human breast cancer cells. Clin Exp Metastasis 2005;22:255-63.
22. Richert MM, Phadke PA, Matters GL, et al. Metastasis of hormone-independent breast cancer to lung and bone is decreased by a-difluoromethylornithine treatment. Breast Cancer Res 2005;7:R819-27.
23. Manni A, Washington S, Craig L, et al. Effects of α- difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice. Clin Exp Metastasis 2003;20:321-5.
24. Fu Z, Smith PC, Zhang L, et al. Effects of Raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J Natl Cancer Inst 2003;95:878-89.
25. Sahai E. Illuminating the metastatic process. Nat Rev Genet 2007;7:737-49.
26. Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol 2006;7:131-42.
27. McIntyre JO, Fingleton B, Wells KS, et al. Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity. Biochem J 2004;377:617-28.
28. Kass L, Erler JT, Dembo M, Weaver VM. Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis. Int J Biochem Cell Biol 2007;39:1987-94.
29. Paszek MJ, Weaver VM. The tension mounts: mechanics meets morphogenesis and malignancy. J Mammary Gland Biol Neoplasia 2004;9:325-42.
30. Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438:820-7.
31. Hoshida T, Isaka N, Hagendoorn J, et al. Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. Cancer Res 2006;66:8065-75.
32. Kitamura T, Kometani K, Hashida H, et al. SMAD4-deficient intestinal tumors recruit CCR1(+) myeloid cells that promote invasion. Nat Genet 2007;39:467-75.
33. Gril B, Palmieri D, Bronder JL, et al. Effect of lapatinibon the outgrowth of metastatic breast cancer cells to the brain. J Natl Cancer Inst 2008;100:1092-103.
34. Steeg PS, Theodorescu D. Metastasis: A therapeutic target for cancer. Nat Clin Pract Oncol 2007;5:206-19.
35. Caunt M, Mak J, Liang WC, et al. Blocking neuropilin-2 function inhibits tumor cell metastasis. Cancer Cell 2008;13:331-42.
36. Gildea JJ, Seraj MJ, Oxford G, et al. RhoGD12 is an invasion and metastasis suppressor gene in human cancer. Cancer Res 2002;62:6418-23.
37. Wu JM, Fackler MJ, Halushka MK, et al. Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases. Clin Cancer Res 2008;14:1938-46.
38. Marangoni E, Vincent-Salomon A, Auger N, et al. A new model of patient tumor-derived breast cancer xenografts for preclinical assays. Clin Cancer Res 2007;13:3989-98.
39. Dhurjati R, Krishnan V, Shuman LA, Mastro AM, Vogler EA. Metastatic breast cancer cells colonize and degrade three-dimensional osteoblastic tissue in vitro. Clin Exp Metastasis 2008;25:753-63.
40. Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA. Autologous chernotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell 2007;11:526-38.
41. Griffith LG, Swartz MA. Capturing complex 3D tissue physiology in vitro. Nat Rev Mol Cell Biol 2006;7:211-24.
42. Awakura Y, Nakamura E, Takahashi T, et al. Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma. J Cancer Res Clin Oncol 2008;10.1007/s00432-008-0412-4.
43. Conn EM, Madsen MA, Cravatt BF, Ruf W, Deryugina EI, Quigley JP. Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation. J Biol Chem 2008;283:26518-27.
44. Hickson J, Diane YS, Berger J, et al. Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis. Clin Exp Metastasis 2008;10.1007/s10585-008-9177-z.
45. Neiditch MB, Federle MJ, Pompeani AJ, et al. Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. Cell 2006;126:1095-108.
46. Irie Y, Parsek MR. Quorum sensing and microbial biofilms. Curr Top Microbiol Immunol 2008;322:67-84.
47. Parsek MR, Greenberg EP. Sociomicrobiology: the connections between quorum sensing and biofilms. Trends Microbiol 2005;13:27-33.
48. Bierie B, Stover DG, Abel TW, et al. Transforming growth factor-β regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. Cancer Res 2008;68:1809-19.
49. Bierie B, Moses HL. TGFβ: the molecular Jekyll and Hyde of cancer. Nat Rev Genet 2006;6:506-20.
50. Singh LS, Berk M, Oates R, et al. Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. J Natl Cancer Inst 2007;99:1313-27.
51. Shaikh FM, Seales EC, Clem WC, Hennessy KM, Zhuo Y, Bellis SL. Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms. Exp Cell Res. In press, 2008.
52. Zhuo Y, Chammas R, Bellis SL. Sialylation of β1 integrins blocks cell adhesion to Galectin-3 and protects cells against Galectin-3-induced apoptosis. J Biol Chem 2008;283:22177-85.
53. McDonald PC, Oloumi A, Mills J, et al. Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival. Cancer Res 2008;68:1618-24.
54. Nash KT, Phadke PA, Navenot J-M, et al. KISS1 metastasis suppressor secretion, multiple organ metastasis suppression, and maintenance of tumor dormancy. J Natl Cancer Inst 2007;99:309-21.
55. Akakura S, Huang C, Nelson PJ, Foster B, Gelman IH. Loss of the SSeCKS/Gravin/AKAP12 gene results in prostatic hyperplasia. Cancer Res 2008;68:5096-103.
56. Montel V, Mose ES, Tarin D. Tumor-stromal interactions reciprocally modulate gene expression patterns during carcinogenesis and metastasis. Int J Cancer 2006;119:251-63.
57. Pantel K, Brakenhoff RH, Brandt B. Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat Rev Genet 2008;8:329-40.
58. Barkan D, Kleinman H, Simmons JL, et al. Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. Cancer Res 2008;68:6241-50.