-
1
-
-
0021951646
-
Effect of concentration of D, 1-2-difluoromethylornithine on murine mammary carcinogenesis
-
HG Thompson LD Meeker EJ Herbst AM Ronan R Minocha 1985 Effect of concentration of D, 1-2-difluoromethylornithine on murine mammary carcinogenesis Cancer Res 45 1170 73
-
(1985)
Cancer Res
, vol.45
, pp. 1170-73
-
-
Thompson, H.G.1
Meeker, L.D.2
Herbst, E.J.3
Ronan, A.M.4
Minocha, R.5
-
2
-
-
0022967255
-
Effect of Tamoxifen and D, 1-2-difluromethylornithine on the growth, ornithine decarboxylase activity, and polyamine content of mammary carcinomas induced by 1-methyl-1-nitrosurea
-
HJ Thompson AM Roman KA Rotacco LD Meeker 1986 Effect of Tamoxifen and D, 1-2-difluromethylornithine on the growth, ornithine decarboxylase activity, and polyamine content of mammary carcinomas induced by 1-methyl-1-nitrosurea Carcinogenesis 7 837 40
-
(1986)
Carcinogenesis
, vol.7
, pp. 837-40
-
-
Thompson, H.J.1
Roman, A.M.2
Rotacco, K.A.3
Meeker, L.D.4
-
4
-
-
0029050065
-
Involvement of the polyamine pathway in breast cancer progression
-
A Manni R Grove S Kunselman L Demers 1995 Involvement of the polyamine pathway in breast cancer progression Cancer Lett 92 49 57
-
(1995)
Cancer Lett
, vol.92
, pp. 49-57
-
-
Manni, A.1
Grove, R.2
Kunselman, S.3
Demers, L.4
-
5
-
-
0029832374
-
Prognostic influence on survival of increased ornithine decarboxylase activity in human breast cancer
-
A Manni D Mauger P Gimotty B Badger 1996 Prognostic influence on survival of increased ornithine decarboxylase activity in human breast cancer Clin Cancer Res 2 1901 5
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1901-5
-
-
Manni, A.1
Mauger, D.2
Gimotty, P.3
Badger, B.4
-
7
-
-
0036211154
-
Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells
-
A Manni S Washington JW Griffith MF Verderame D Mauger LM Demers RS Samant DR Welch 2002 Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells Clin Exptl Mets 19 95 105
-
(2002)
Clin Exptl Mets
, vol.19
, pp. 95-105
-
-
Manni, A.1
Washington, S.2
Griffith, J.W.3
Verderame, M.F.4
Mauger, D.5
Demers, L.M.6
Samant, R.S.7
Welch, D.R.8
-
8
-
-
0038199842
-
Effects of α-difluoromethylornitine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice
-
A Manni S Washington L Craig M Cloud JW Griffith MF Verderame LJ Texter D Mauger LM Demers JF Harms DR Welch 2003 Effects of α- difluoromethylornitine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice Clin Exptl Mets 20 321 5
-
(2003)
Clin Exptl Mets
, vol.20
, pp. 321-5
-
-
Manni, A.1
Washington, S.2
Craig, L.3
Cloud, M.4
Griffith, J.W.5
Verderame, M.F.6
Texter, L.J.7
Mauger, D.8
Demers, L.M.9
Harms, J.F.10
Welch, D.R.11
-
9
-
-
0028361273
-
CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity
-
U Regenass H Mett J Stanek M Muller D Kramer CW Porter 1994 CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity Cancer Res 54 3210 3217
-
(1994)
Cancer Res
, vol.54
, pp. 3210-3217
-
-
Regenass, U.1
Mett, H.2
Stanek, J.3
Muller, M.4
Kramer, D.5
Porter, C.W.6
-
10
-
-
0029142821
-
Biochemical and growth-modulatory effects of the new S-adenosylmethionine decarboxylase inhibitor GCP 48664 in malignant and immortalized normal human breast epithelial cells in culture
-
A Manni B Badger R Wechter S Kunselman A Rossini L Demers 1995 Biochemical and growth-modulatory effects of the new S-adenosylmethionine decarboxylase inhibitor GCP 48664 in malignant and immortalized normal human breast epithelial cells in culture Int J Cancer 62 485 91
-
(1995)
Int J Cancer
, vol.62
, pp. 485-91
-
-
Manni, A.1
Badger, B.2
Wechter, R.3
Kunselman, S.4
Rossini, A.5
Demers, L.6
-
11
-
-
0035992316
-
A phase I and pharmacokinetic study of SAM486A, a novel polyamine biosynthesis inhibitor, administered on a daily-times-five every-three-week schedule in patients with advanced solid malignancies
-
LI Siu ER Rowinsky LA Hammond GR Weiss M Hidalgo GM Clark J Moczygemba L Choi R Linnartz NC Barbet IT Sklenar R Capdeville G Gan CW Porter DD Von Hoff SG Eckhardt 2002 A phase I and pharmacokinetic study of SAM486A, a novel polyamine biosynthesis inhibitor, administered on a daily-times-five every-three-week schedule in patients with advanced solid malignancies Clin Cancer Res 8 2156 66
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2156-66
-
-
Siu, L.I.1
Rowinsky, E.R.2
Hammond, L.A.3
Weiss, G.R.4
Hidalgo, M.5
Clark, G.M.6
Moczygemba, J.7
Choi, L.8
Linnartz, R.9
Barbet, N.C.10
Sklenar, I.T.11
Capdeville, R.12
Gan, G.13
Porter, C.W.14
Von Hoff, D.D.15
Eckhardt, S.G.16
-
12
-
-
16644386863
-
Biological activity of the S-adenosylmethionine decarboxylase (SAMDC) inhibitor SAM486A in human breast cancer cells in vitro and in vivo
-
X Hu S Washington MF Verderame LM Demers D Mauger A Manni 2004 Biological activity of the S-adenosylmethionine decarboxylase (SAMDC) inhibitor SAM486A in human breast cancer cells in vitro and in vivo Int J Oncol 25 1831 8
-
(2004)
Int J Oncol
, vol.25
, pp. 1831-8
-
-
Hu, X.1
Washington, S.2
Verderame, M.F.3
Demers, L.M.4
Mauger, D.5
Manni, A.6
-
13
-
-
0035434563
-
S-adenosylmethionine decarboxylase (SAMDC) overexpression reduces invasiveness and tumorigenicity in nude mice of MCF-7 breast cancer cells
-
A Manni S Fischer M Franks S Washington R DeArment J Griffith L Demers M Verderame B Leiby D Mauger 2002 S-adenosylmethionine decarboxylase (SAMDC) overexpression reduces invasiveness and tumorigenicity in nude mice of MCF-7 breast cancer cells Int J Oncol 19 317 23
-
(2002)
Int J Oncol
, vol.19
, pp. 317-23
-
-
Manni, A.1
Fischer, S.2
Franks, M.3
Washington, S.4
Dearment, R.5
Griffith, J.6
Demers, L.7
Verderame, M.8
Leiby, B.9
Mauger, D.10
-
15
-
-
12444340846
-
Cellular mechanisms mediating the anti-invasive properties of the ornithine decarboxylase inhibitor α-difluoromethylornithine (DFMO) in human breast cancer cells
-
A Manni S Washington D Mauger DA Hackett MF Verderame 2004 Cellular mechanisms mediating the anti-invasive properties of the ornithine decarboxylase inhibitor α-difluoromethylornithine (DFMO) in human breast cancer cells Clin Experim Metastasis 21 461 7
-
(2004)
Clin Experim Metastasis
, vol.21
, pp. 461-7
-
-
Manni, A.1
Washington, S.2
Mauger, D.3
Hackett, D.A.4
Verderame, M.F.5
-
16
-
-
0035403794
-
Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer
-
K Maeda Y Nishiguchi SM Kang M Yashiro N Onoda T Sawada T Ishikawa K Hirakawa 2001 Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer Oncol Rep 8 763 6
-
(2001)
Oncol Rep
, vol.8
, pp. 763-6
-
-
Maeda, K.1
Nishiguchi, Y.2
Kang, S.M.3
Yashiro, M.4
Onoda, N.5
Sawada, T.6
Ishikawa, T.7
Hirakawa, K.8
-
17
-
-
0028089956
-
Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines
-
V Zabrenetzky CC Harris PS Steeg DD Roberts 1994 Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines Int J Cancer 59 191 5
-
(1994)
Int J Cancer
, vol.59
, pp. 191-5
-
-
Zabrenetzky, V.1
Harris, C.C.2
Steeg, P.S.3
Roberts, D.D.4
-
18
-
-
0028609624
-
Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis
-
DL Weinstat-Saslow VS Zabrenetzky K VanHoutte WA Frazier DD Roberts PS Steeg 1994 Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis Cancer Res 54 6504 11
-
(1994)
Cancer Res
, vol.54
, pp. 6504-11
-
-
Weinstat-Saslow, D.L.1
Zabrenetzky, V.S.2
Vanhoutte, K.3
Frazier, W.A.4
Roberts, D.D.5
Steeg, P.S.6
-
19
-
-
0034782501
-
Adjuvant systemic therapy for early breast cancer: Progress and controversies
-
GN Hortobagyi 2001 Adjuvant systemic therapy for early breast cancer: progress and controversies Clinical Cancer Res 7 1839 42
-
(2001)
Clinical Cancer Res
, vol.7
, pp. 1839-42
-
-
Hortobagyi, G.N.1
-
20
-
-
12544256390
-
Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s)
-
S Kamada U Kikkawa Y Tsujimoto T Hunter 2005 Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s) J Biol Chem 280 857 60
-
(2005)
J Biol Chem
, vol.280
, pp. 857-60
-
-
Kamada, S.1
Kikkawa, U.2
Tsujimoto, Y.3
Hunter, T.4
-
21
-
-
0032895918
-
Polyamine depletion arrests cell cycle and induces inhibitors p21(Waf1/Cip1), p27(Kip1), and p53 in IEC-6 cells
-
RM Ray BJ Zimmerman SA McCormack TB Patel LR Johnson 1999 Polyamine depletion arrests cell cycle and induces inhibitors p21(Waf1/Cip1), p27(Kip1), and p53 in IEC-6 cells Am J Physiol 276 C684 91
-
(1999)
Am J Physiol
, vol.276
, pp. 684-91
-
-
Ray, R.M.1
Zimmerman, B.J.2
McCormack, S.A.3
Patel, T.B.4
Johnson, L.R.5
-
22
-
-
0038418341
-
The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells
-
Y Chen K Alm S Vujcic DL Kramer K Kee P Diegelman CW Porter 2003 The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells Cancer Res 63 3619 25
-
(2003)
Cancer Res
, vol.63
, pp. 3619-25
-
-
Chen, Y.1
Alm, K.2
Vujcic, S.3
Kramer, D.L.4
Kee, K.5
Diegelman, P.6
Porter, C.W.7
-
23
-
-
0031981867
-
Cooperativity between the polyamine pathway and HER-2neu in transformation of human mammary epithelial cells in culture: Role of the MAPK pathway
-
A Manni R Wechter MF Verderame D Mauger 1998 Cooperativity between the polyamine pathway and HER-2neu in transformation of human mammary epithelial cells in culture: role of the MAPK pathway Int J Cancer 76 563 70
-
(1998)
Int J Cancer
, vol.76
, pp. 563-70
-
-
Manni, A.1
Wechter, R.2
Verderame, M.F.3
Mauger, D.4
-
24
-
-
0030935710
-
Ornithine decarboxylase overexpression in mouse 10T1/2 fibroblasts: Cellular transformation and invasion
-
S Kubota H Kiyosawa Y Nomura T Yamada Y Seyama 1997 Ornithine decarboxylase overexpression in mouse 10T1/2 fibroblasts: cellular transformation and invasion J Nat Cancer Inst 89 567 71
-
(1997)
J Nat Cancer Inst
, vol.89
, pp. 567-71
-
-
Kubota, S.1
Kiyosawa, H.2
Nomura, Y.3
Yamada, T.4
Seyama, Y.5
-
25
-
-
0030823407
-
The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. Dependence on the availability of downstream targets
-
KE Bornfeldt JS Campbell H Koyama GM Argast CL Leslie EW Raines 1997 The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. Dependence on the availability of downstream targets J Clin Invest 100 875 885
-
(1997)
J Clin Invest
, vol.100
, pp. 875-885
-
-
Bornfeldt, K.E.1
Campbell, J.S.2
Koyama, H.3
Argast, G.M.4
Leslie, C.L.5
Raines, E.W.6
-
26
-
-
0031028381
-
Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway
-
KM Pumiglia SJ Decker 1997 Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway Proc Natl Acad Sci USA 94 448 452
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 448-452
-
-
Pumiglia, K.M.1
Decker, S.J.2
-
27
-
-
0030972462
-
Constitutively active mutant of mitogen-activated protein kinase kinase MEK1 induces epithelial differentiation and growth inhibition in Madin-Darby canine kidney-C7 cells
-
H Schramek E Feifel E Healy V Pollack 1997 Constitutively active mutant of mitogen-activated protein kinase kinase MEK1 induces epithelial differentiation and growth inhibition in Madin-Darby canine kidney-C7 cells J Biol Chem 272 11426 33
-
(1997)
J Biol Chem
, vol.272
, pp. 11426-33
-
-
Schramek, H.1
Feifel, E.2
Healy, E.3
Pollack, V.4
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