Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity

PLoS Genetics

Volumn 4, Issue 11, 2008, Pages

  Nandakumar, Madhumitha ^a   Tan, Man Wah ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA LINOLENIC ACID; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE P38; OMEGA 6 FATTY ACID; OSTEOPONTIN; POLYPEPTIDE ANTIBIOTIC AGENT; POLYUNSATURATED FATTY ACID; STEARIDONIC ACID; CADHERIN; CAENORHABDITIS ELEGANS PROTEIN; EPIDERMAL GROWTH FACTOR; FAT3 PROTEIN, C ELEGANS; MITOGEN ACTIVATED PROTEIN KINASE; OMEGA 3 FATTY ACID; PMK 1 PROTEIN, C ELEGANS; PMK-1 PROTEIN, C ELEGANS; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; CAENORHABDITIS ELEGANS; ENZYME ACTIVITY; GENE EXPRESSION; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; INFECTION SENSITIVITY; INNATE IMMUNITY; INTESTINE; METAZOON; NONHUMAN; OXIDATIVE STRESS; PSEUDOMONAS AERUGINOSA; TRANSCRIPTION INITIATION; ANIMAL; DRUG EFFECT; ENZYMOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALIA; BACTERIA (MICROORGANISMS); CAENORHABDITIS ELEGANS; METAZOA; PSEUDOMONAS AERUGINOSA;

ANIMALS; CADHERINS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EPIDERMAL GROWTH FACTOR; FATTY ACIDS, OMEGA-3; GAMMA-LINOLENIC ACID; IMMUNITY, INNATE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 57149085057     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000273     Document Type: Article

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