A newly established in vitro culture using transgenic Drosophila reveals functional coupling between the phospholipase A2-generated fatty acid cascade and lipopolysaccharide-dependent activation of the immune deficiency (imd) pathway in insect immunity

Biochemical Journal

Volumn 371, Issue 1, 2003, Pages 205-210

  Yajima, Masashi ^a   Takada, Masatoshi ^a   Takahashi, Nahoko ^a   Kikuchi, Haruhisa ^a   Natori, Shunji ^b   Oshima, Yoshiteru ^a   Kurata, Shoichiro ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

Host defence; Innate immunity; Nuclear factor B (NF B); Tumour necrosis factor (TNF)

Indexed keywords

ANTIGENS; FATTY ACIDS; IMMUNIZATION; MICROORGANISMS;

BACTERIAL INFECTIONS;

BIOCHEMISTRY;

4 BROMOPHENACYL BROMIDE; ARACHIDONIC ACID; DEXAMETHASONE; FATTY ACID; GAMMA LINOLENIC ACID; ICOSAPENTAENOIC ACID; LIPOPOLYSACCHARIDE; PHOSPHOLIPASE A2; 4-BROMOPHENACYL BROMIDE; ACETOPHENONE DERIVATIVE; DPT PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; ENZYME INHIBITOR; GREEN FLUORESCENT PROTEIN; INSECT PROTEIN; PHOSPHOLIPASE A; PHOTOPROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL INFECTION; CELL CULTURE; DROSOPHILA; DRUG SCREENING; ENZYME INHIBITION; IMMUNE DEFICIENCY; IMMUNITY; IN VITRO STUDY; INSECT; MAMMAL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL; ANIMAL; BIOASSAY; DRUG ANTAGONISM; DRUG EFFECT; FLY; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; LARVA; METABOLISM; METHODOLOGY; PHYSIOLOGY; REPORTER GENE;

ANIMALIA; ARACHNIDA; BACTERIA (MICROORGANISMS); HEXAPODA; INSECTA; MAMMALIA;

ACETOPHENONES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ARACHIDONIC ACID; BIOLOGICAL ASSAY; DEXAMETHASONE; DIPTERA; DROSOPHILA; DROSOPHILA PROTEINS; ENZYME INHIBITORS; FATTY ACIDS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; IMMUNITY, NATURAL; INSECT PROTEINS; LARVA; LIPOPOLYSACCHARIDES; LUMINESCENT PROTEINS; PHOSPHOLIPASES A; SIGNAL TRANSDUCTION;

EID: 0037393120     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021603     Document Type: Article

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