-
1
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007; 39:207-211.
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
2
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39:596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
3
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
The Wellcome Trust Case Control Consortium
-
The Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
4
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40:955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
5
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg1611 in mouse and human intestinal Paneth cells
-
doi:10.1038/nature07416
-
Cadwell K, Liu JY, Brown SL, et al. A key role for autophagy and the autophagy gene Atg1611 in mouse and human intestinal Paneth cells. Nature 2008; doi:10.1038/nature07416.
-
(2008)
Nature
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
-
6
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
doi:10.1038/nature07383
-
Saitoh T, Fujita N, Jang MH. et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008; doi:10.1038/nature07383.
-
(2008)
Nature
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
-
7
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005; 307:731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
-
8
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1-beta processing
-
Maeda S, Hsu LC, Liu H, et al. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1-beta processing. Science 2005; 307:734-738.
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
-
9
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
KaserA, Lee AH, Franke A, et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 2008; 134:743-756.
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
-
10
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS ONE 2008; 3:e3391.
-
(2008)
PLoS ONE
, vol.3
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
Daly, M.J.4
Xavier, R.J.5
-
11
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe T, Kitani A, Murray PJ, Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 2004; 5:800-808.
-
(2004)
Nat Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Strober, W.4
-
12
-
-
37649013801
-
Chronic stimulation of Nod2 mediates tolerance to bacterial products
-
Hedl M, Li J, Cho JH, Abraham C. Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proc Natl Acad Sci USA 2007; 104:19440-19445.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19440-19445
-
-
Hedl, M.1
Li, J.2
Cho, J.H.3
Abraham, C.4
-
13
-
-
0030863618
-
Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice
-
Garabedian EM, Roberts LJ, McNevin MS, Gordon JI. Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice. J Biol Chem 1997; 272: 23729-23740.
-
(1997)
J Biol Chem
, vol.272
, pp. 23729-23740
-
-
Garabedian, E.M.1
Roberts, L.J.2
McNevin, M.S.3
Gordon, J.I.4
-
14
-
-
0033214433
-
Regulation of intestinal alphadefensin activation by the metalloproteinase matrilysin in innate host defense
-
Wilson CL, Ouellette AJ, Satchell DP, et al. Regulation of intestinal alphadefensin activation by the metalloproteinase matrilysin in innate host defense. Science 1999; 286:113-7.
-
(1999)
Science
, vol.286
, pp. 113-117
-
-
Wilson, C.L.1
Ouellette, A.J.2
Satchell, D.P.3
-
15
-
-
50249116184
-
The endoplasmic reticulum stress response in immunity and autoimmunity
-
Todd DJ, Lee AH, Glimcher LH. The endoplasmic reticulum stress response in immunity and autoimmunity. Nat Rev Immunol 2008; 8:663-674.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 663-674
-
-
Todd, D.J.1
Lee, A.H.2
Glimcher, L.H.3
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