-
1
-
-
0033540030
-
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
-
Beck T, Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402, 689-692.
-
(1999)
Nature
, vol.402
, pp. 689-692
-
-
Beck, T.1
Hall, M.N.2
-
2
-
-
4644255309
-
The novel yeast PAS kinase Rim 15 orchestrates G0-associated antioxidant defense mechanisms
-
Cameroni E, Hulo N, Roosen J, Winderickx J, De Virgilio C (2004) The novel yeast PAS kinase Rim 15 orchestrates G0-associated antioxidant defense mechanisms. Cell Cycle 3, 462-468.
-
(2004)
Cell Cycle
, vol.3
, pp. 462-468
-
-
Cameroni, E.1
Hulo, N.2
Roosen, J.3
Winderickx, J.4
De Virgilio, C.5
-
3
-
-
27544516094
-
Ubiquitin - Conserved protein or selfish gene?
-
Catic A, Ploegh HL (2005) Ubiquitin - conserved protein or selfish gene? Trends Biochem. Sci. 30, 600-604.
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 600-604
-
-
Catic, A.1
Ploegh, H.L.2
-
4
-
-
34447646492
-
Longevity determined by developmental arrest genes in Caenorhabditis elegans
-
Chen D, Pan KZ, Palter JE, Kapahi P (2007) Longevity determined by developmental arrest genes in Caenorhabditis elegans. Aging Cell 6, 525-533.
-
(2007)
Aging Cell
, vol.6
, pp. 525-533
-
-
Chen, D.1
Pan, K.Z.2
Palter, J.E.3
Kapahi, P.4
-
5
-
-
3843061402
-
Sirolimus-eluting coronary stents: Novel devices for the management of coronary artery disease
-
Cheng-Lai A, Frishman WH (2004) Sirolimus-eluting coronary stents: Novel devices for the management of coronary artery disease. Am. J. Ther. 11, 218-228.
-
(2004)
Am. J. Ther.
, vol.11
, pp. 218-228
-
-
Cheng-Lai, A.1
Frishman, W.H.2
-
6
-
-
33847680031
-
Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span
-
Chiocchetti A, Zhou J, Zhu H, Karl T, Haubenreisser O, Rinnerthaler M, Heeren G, Oender K, Bauer J, Hintner H, Breitenbach M, Breitenbach-Koller L (2007) Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span. Exp. Gerontol. 42, 275-286.
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 275-286
-
-
Chiocchetti, A.1
Zhou, J.2
Zhu, H.3
Karl, T.4
Haubenreisser, O.5
Rinnerthaler, M.6
Heeren, G.7
Oender, K.8
Bauer, J.9
Hintner, H.10
Breitenbach, M.11
Breitenbach-Koller, L.12
-
7
-
-
33748792821
-
Opposing activities protect against age-onset proteotoxicity
-
Cohen E, Bieschke J, Perciavalle RM, Kelly JW, Dillin A (2006) Opposing activities protect against age-onset proteotoxicity. Science 313, 1604-1610.
-
(2006)
Science
, vol.313
, pp. 1604-1610
-
-
Cohen, E.1
Bieschke, J.2
Perciavalle, R.M.3
Kelly, J.W.4
Dillin, A.5
-
8
-
-
34247569105
-
Lifespan regulation by evolutionarily conserved genes essential for viability
-
Curran SP, Ruvkun G (2007) Lifespan regulation by evolutionarily conserved genes essential for viability. PLoS Genet. 3, e56.
-
(2007)
PLoS Genet.
, vol.3
-
-
Curran, S.P.1
Ruvkun, G.2
-
9
-
-
0037280096
-
SOD2 functions downstream of Sch9 to extend longevity in yeast
-
Fabrizio P, Liou LL, Moy VN, Diaspro A, SelverstoneValentine J, Gralla EB, Longo VD (2003) SOD2 functions downstream of Sch9 to extend longevity in yeast. Genetics 163, 35-46.
-
(2003)
Genetics
, vol.163
, pp. 35-46
-
-
Fabrizio, P.1
Liou, L.L.2
Moy, V.N.3
Diaspro, A.4
SelverstoneValentine, J.5
Gralla, E.B.6
Longo, V.D.7
-
10
-
-
0035853552
-
Regulation of longevity and stress resistance by Sch9 in yeast
-
Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD (2001) Regulation of longevity and stress resistance by Sch9 in yeast. Science 292, 288-290.
-
(2001)
Science
, vol.292
, pp. 288-290
-
-
Fabrizio, P.1
Pozza, F.2
Pletcher, S.D.3
Gendron, C.M.4
Longo, V.D.5
-
12
-
-
33746699629
-
Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis
-
Gao XM, Wong G, Wang B, Kiriazis H, Moore XL, Su YD, Dart A, Du XJ (2006) Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis. J. Hypertens. 24, 1663-1670.
-
(2006)
J. Hypertens.
, vol.24
, pp. 1663-1670
-
-
Gao, X.M.1
Wong, G.2
Wang, B.3
Kiriazis, H.4
Moore, X.L.5
Su, Y.D.6
Dart, A.7
Du, X.J.8
-
13
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
-
Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C (2008) A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet 4, e24.
-
(2008)
PLoS Genet
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
14
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C (2007) Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6, 95-110.
-
(2007)
Aging Cell
, vol.6
, pp. 95-110
-
-
Hansen, M.1
Taubert, S.2
Crawford, D.3
Libina, N.4
Lee, S.J.5
Kenyon, C.6
-
15
-
-
27144510561
-
Translational regulation of GCN4 and the general amino acid control of yeast
-
Hinnebusch AG (2005) Translational regulation of GCN4 and the general amino acid control of yeast. Annu. Rev. Microbiol. 59, 407-450.
-
(2005)
Annu. Rev. Microbiol.
, vol.59
, pp. 407-450
-
-
Hinnebusch, A.G.1
-
16
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu AL, Murphy CT, Kenyon C (2003) Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300, 1142-1145.
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
17
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
Jia K, Chen D, Riddle DL (2004) The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131, 3897-3906.
-
(2004)
Development
, vol.131
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.L.3
-
18
-
-
0034625801
-
Global expression profiling of yeast treated with an inhibitor of amino acid biosynthesis, sulfometuron methyl
-
Jia MH, Larossa RA, Lee JM, Rafalski A, Derose E, Gonye G, Xue Z (2000) Global expression profiling of yeast treated with an inhibitor of amino acid biosynthesis, sulfometuron methyl. Physiol. Genomics 3, 83-92.
-
(2000)
Physiol. Genomics
, vol.3
, pp. 83-92
-
-
Jia, M.H.1
Larossa, R.A.2
Lee, J.M.3
Rafalski, A.4
Derose, E.5
Gonye, G.6
Xue, Z.7
-
19
-
-
36849021043
-
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
-
Juhasz G, Erdi B, Sass M, Neufeld TP (2007) Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Genes Dev. 21, 3061-3066.
-
(2007)
Genes Dev.
, vol.21
, pp. 3061-3066
-
-
Juhasz, G.1
Erdi, B.2
Sass, M.3
Neufeld, T.P.4
-
20
-
-
34247584147
-
Longevity genomics across species
-
Kaeberlein M (2007) Longevity genomics across species. Curr. Genomics 8, 73-78.
-
(2007)
Curr. Genomics
, vol.8
, pp. 73-78
-
-
Kaeberlein, M.1
-
22
-
-
27744511769
-
Regulation of yeast replicative life-span by TOR and Sch9 in response to nutrients
-
Kaeberlein M, Powers RW III, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, Kennedy BK (2005) Regulation of yeast replicative life-span by TOR and Sch9 in response to nutrients. Science 310, 1193-1196.
-
(2005)
Science
, vol.310
, pp. 1193-1196
-
-
Kaeberlein, M.1
Powers, R.W.2
Steffen, K.K.3
Westman, E.A.4
Hu, D.5
Dang, N.6
Kerr, E.O.7
Kirkland, K.T.8
Fields, S.9
Kennedy, B.K.10
-
23
-
-
33751250243
-
Lifespan extension in Caenorhabditis elegans by complete removal of food
-
Kaeberlein TL, Smith ED, Tsuchiya M, Welton KL, Thomas JH, Fields S, Kennedy BK, Kaeberlein M (2006) Lifespan extension in Caenorhabditis elegans by complete removal of food. Aging Cell 5, 487-494.
-
(2006)
Aging Cell
, vol.5
, pp. 487-494
-
-
Kaeberlein, T.L.1
Smith, E.D.2
Tsuchiya, M.3
Welton, K.L.4
Thomas, J.H.5
Fields, S.6
Kennedy, B.K.7
Kaeberlein, M.8
-
24
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
-
Kapahi P, Zid BM, Harper T, Koslover D, Sapin V, Benzer S (2004) Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 14, 885-890.
-
(2004)
Curr. Biol.
, vol.14
, pp. 885-890
-
-
Kapahi, P.1
Zid, B.M.2
Harper, T.3
Koslover, D.4
Sapin, V.5
Benzer, S.6
-
25
-
-
38349109305
-
The genetics of ageing: Insight from genome-wide approaches in invertebrate model organisms
-
Kennedy BK (2008) The genetics of ageing: Insight from genome-wide approaches in invertebrate model organisms. J. Intern. Med. 263, 142-152.
-
(2008)
J. Intern. Med.
, vol.263
, pp. 142-152
-
-
Kennedy, B.K.1
-
26
-
-
35548973466
-
Functional specificity among ribosomal proteins regulates gene expression
-
Komili S, Farny NG, Roth FP, Silver PA (2007) Functional specificity among ribosomal proteins regulates gene expression. Cell 131, 557-571.
-
(2007)
Cell
, vol.131
, pp. 557-571
-
-
Komili, S.1
Farny, N.G.2
Roth, F.P.3
Silver, P.A.4
-
27
-
-
33751203889
-
Dietary deprivation extends lifespan in Caenorhabditis elegans
-
Lee GD, Wilson MA, Zhu M, Wolkow CA, de Cabo R, Ingram DK, Zou S (2006) Dietary deprivation extends lifespan in Caenorhabditis elegans. Aging Cell 5, 515-524.
-
(2006)
Aging Cell
, vol.5
, pp. 515-524
-
-
Lee, G.D.1
Wilson, M.A.2
Zhu, M.3
Wolkow, C.A.4
de Cabo, R.5
Ingram, D.K.6
Zou, S.7
-
28
-
-
34548634634
-
Transcriptional response to aging and caloric restriction in heart and adipose tissue
-
Linford NJ, Beyer RP, Gollahon K, Krajcik RA, Malloy VL, Demas V, Burmer GC, Rabinovitch PS (2007) Transcriptional response to aging and caloric restriction in heart and adipose tissue. Aging Cell 6, 673-688.
-
(2007)
Aging Cell
, vol.6
, pp. 673-688
-
-
Linford, N.J.1
Beyer, R.P.2
Gollahon, K.3
Krajcik, R.A.4
Malloy, V.L.5
Demas, V.6
Burmer, G.C.7
Rabinovitch, P.S.8
-
29
-
-
33644987746
-
Conversion of green fluorescent protein into a toxic, aggregation-prone protein by C-terminal addition of a short peptide
-
Link CD, Fonte V, Hiester B, Yerg J, Ferguson J, Csontos S, Silverman MA, Stein GH (2006) Conversion of green fluorescent protein into a toxic, aggregation-prone protein by C-terminal addition of a short peptide. J. Biol. Chem. 281, 1808-1816.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1808-1816
-
-
Link, C.D.1
Fonte, V.2
Hiester, B.3
Yerg, J.4
Ferguson, J.5
Csontos, S.6
Silverman, M.A.7
Stein, G.H.8
-
30
-
-
35648995939
-
MSN2 and MSN4 link calorie restriction and TOR to Sirtuin-mediated lifespan extension in Saccharomyces cerevisiae
-
Medvedik O, Lamming DW, Kim KD, Sinclair DA (2007) MSN2 and MSN4 link calorie restriction and TOR to Sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLOS Biol. 5, 230-241.
-
(2007)
PLOS Biol.
, vol.5
, pp. 230-241
-
-
Medvedik, O.1
Lamming, D.W.2
Kim, K.D.3
Sinclair, D.A.4
-
31
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
Melendez A, Talloczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B (2003) Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301, 1387-1391.
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Melendez, A.1
Talloczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
32
-
-
34547801661
-
S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover
-
Mieulet V, Roceri M, Espeillac C, Sotiropoulos A, Ohanna M, Oorschot V, Klumperman J, Sandri M, Pende M (2007) S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover. Am. J. Physiol. Cell Physiol. 293, C712-C722.
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.293
-
-
Mieulet, V.1
Roceri, M.2
Espeillac, C.3
Sotiropoulos, A.4
Ohanna, M.5
Oorschot, V.6
Klumperman, J.7
Sandri, M.8
Pende, M.9
-
33
-
-
34447635239
-
An Aging Interventions Testing Program: Study design and interim report
-
Miller RA, Harrison DE, Astle CM, Floyd RA, Flurkey K, Hensley KL, Javors MA, Leeuwenburgh C, Nelson JF, Ongini E, Nadon NL, Warner HR, Strong R (2007) An Aging Interventions Testing Program: Study design and interim report. Aging Cell 6, 565-575.
-
(2007)
Aging Cell
, vol.6
, pp. 565-575
-
-
Miller, R.A.1
Harrison, D.E.2
Astle, C.M.3
Floyd, R.A.4
Flurkey, K.5
Hensley, K.L.6
Javors, M.A.7
Leeuwenburgh, C.8
Nelson, J.F.9
Ongini, E.10
Nadon, N.L.11
Warner, H.R.12
Strong, R.13
-
34
-
-
33748339570
-
C. elegans feeding defective mutants have shorter body lengths and increased autophagy
-
Morck C, Pilon M (2006) C. elegans feeding defective mutants have shorter body lengths and increased autophagy. BMC Dev. Biol. 6, 39.
-
(2006)
BMC Dev. Biol.
, vol.6
, pp. 39
-
-
Morck, C.1
Pilon, M.2
-
35
-
-
0034973590
-
Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast
-
Natarajan K, Meyer MR, Jackson BM, Slade D, Roberts C, Hinnebusch AG, Marton MJ (2001) Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol. Cell Biol. 21, 4347-4368.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 4347-4368
-
-
Natarajan, K.1
Meyer, M.R.2
Jackson, B.M.3
Slade, D.4
Roberts, C.5
Hinnebusch, A.G.6
Marton, M.J.7
-
36
-
-
20044392290
-
Atrophy of S6K1 (-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control
-
Ohanna M, Sobering AK, Lapointe T, Lorenzo L, Praud C, Petroulakis E, Sonenberg N, Kelly PA, Sotiropoulos A, Pende M (2005) Atrophy of S6K1 (-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. Nat. Cell Biol. 7, 286-294.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 286-294
-
-
Ohanna, M.1
Sobering, A.K.2
Lapointe, T.3
Lorenzo, L.4
Praud, C.5
Petroulakis, E.6
Sonenberg, N.7
Kelly, P.A.8
Sotiropoulos, A.9
Pende, M.10
-
37
-
-
33846418352
-
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
-
Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, Lithgow GJ, Kapahi P (2007) Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6, 111-119.
-
(2007)
Aging Cell
, vol.6
, pp. 111-119
-
-
Pan, K.Z.1
Palter, J.E.2
Rogers, A.N.3
Olsen, A.4
Chen, D.5
Lithgow, G.J.6
Kapahi, P.7
-
38
-
-
13944282128
-
Sex and death: What is the connection?
-
Partridge L, Gems D, Withers DJ (2005) Sex and death: What is the connection? Cell 120, 461-472.
-
(2005)
Cell
, vol.120
, pp. 461-472
-
-
Partridge, L.1
Gems, D.2
Withers, D.J.3
-
39
-
-
19444370807
-
Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response
-
Patil CK, Li H, Walter P (2004) Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response. Plos Biol. 2, E246.
-
(2004)
Plos Biol.
, vol.2
-
-
Patil, C.K.1
Li, H.2
Walter, P.3
-
40
-
-
0342657757
-
Saccharomyces cerevisiae Ras/cAMP pathway controls post-diauxic shift element-dependent transcription through the zinc finger protein Gis1
-
Pedruzzi I, Burckert N, Egger P, De Virgilio C (2000) Saccharomyces cerevisiae Ras/cAMP pathway controls post-diauxic shift element-dependent transcription through the zinc finger protein Gis1. EMBO J. 19, 2569-2579.
-
(2000)
EMBO J.
, vol.19
, pp. 2569-2579
-
-
Pedruzzi, I.1
Burckert, N.2
Egger, P.3
De Virgilio, C.4
-
41
-
-
38349103636
-
Separating cause from effect: How does insulin/IGF signalling control lifespan in worms, flies and mice?
-
Piper MD, Selman C, McElwee JJ, Partridge L (2008) Separating cause from effect: How does insulin/IGF signalling control lifespan in worms, flies and mice? J. Intern. Med. 263, 179-191.
-
(2008)
J. Intern. Med.
, vol.263
, pp. 179-191
-
-
Piper, M.D.1
Selman, C.2
McElwee, J.J.3
Partridge, L.4
-
42
-
-
30944458446
-
Extension of chronological life span in yeast by decreased TOR pathway signaling
-
Powers RW, 3rd Kaeberlein M, Caldwell SD, Kennedy BK, Fields S (2006) Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev 20, 174-184.
-
(2006)
Genes Dev
, vol.20
, pp. 174-184
-
-
Powers, R.W.1
Kaeberlein III, M.2
Caldwell, S.D.3
Kennedy, B.K.4
Fields, S.5
-
43
-
-
41649094265
-
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species
-
Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DEL, Thomas JH, Kaeberlein M, Kennedy BK (2008) Quantitative evidence for conserved longevity pathways between divergent eukaryotic species. Genome Res. 18, 564-570.
-
(2008)
Genome Res.
, vol.18
, pp. 564-570
-
-
Smith, E.D.1
Tsuchiya, M.2
Fox, L.A.3
Dang, N.4
Hu, D.5
Kerr, E.O.6
Johnston, E.D.7
Tchao, B.N.8
Pak, D.N.9
Welton, K.L.10
Promislow, D.E.L.11
Thomas, J.H.12
Kaeberlein, M.13
Kennedy, B.K.14
-
44
-
-
0032127462
-
Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation
-
Smith A, Ward MP, Garrett S (1998) Yeast PKA represses Msn2p/ Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation. EMBO J. 17, 3556-3564.
-
(1998)
EMBO J.
, vol.17
, pp. 3556-3564
-
-
Smith, A.1
Ward, M.P.2
Garrett, S.3
-
45
-
-
41949089130
-
Yeast lifespan extension by depletion of 60S ribosomal subunits is mediated by Gcn4
-
Steffen KK, MacKay VL, Kerr EO, Tsuchiya M, Hu D, Fox LA, Dang N, Johnston ED, Oakes JA, Tchao BN, Pak DN, Fields S, Kennedy BK, Kaeberlein M (2008) Yeast lifespan extension by depletion of 60S ribosomal subunits is mediated by Gcn4. Cell 133, 292-302.
-
(2008)
Cell
, vol.133
, pp. 292-302
-
-
Steffen, K.K.1
MacKay, V.L.2
Kerr, E.O.3
Tsuchiya, M.4
Hu, D.5
Fox, L.A.6
Dang, N.7
Johnston, E.D.8
Oakes, J.A.9
Tchao, B.N.10
Pak, D.N.11
Fields, S.12
Kennedy, B.K.13
Kaeberlein, M.14
-
46
-
-
43449138491
-
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans
-
Steinkraus KA, Smith ED, Davis C, Carr D, Pendergrass WR, Sutphin GL, Kennedy BK, Kaeberlein M (2008) Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans. Aging Cell 7, 394-404.
-
(2008)
Aging Cell
, vol.7
, pp. 394-404
-
-
Steinkraus, K.A.1
Smith, E.D.2
Davis, C.3
Carr, D.4
Pendergrass, W.R.5
Sutphin, G.L.6
Kennedy, B.K.7
Kaeberlein, M.8
-
47
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
Takeshige K, Baba M, Tsuboi S, Noda T, Ohsumi Y (1992) Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119, 301-311.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
48
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
Um SH, D'Alessio D, Thomas G (2006) Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab 3, 393-402.
-
(2006)
Cell Metab
, vol.3
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
49
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini PR, Kozma SC, Auwerx J, Thomas G (2004) Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 431, 200-205.
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
Fumagalli, S.7
Allegrini, P.R.8
Kozma, S.C.9
Auwerx, J.10
Thomas, G.11
-
50
-
-
34249813098
-
Sch9 is a major target of TORC1 in Saccharomyces cerevisiae
-
Urban J, Soulard A, Huber A, Lippman S, Mukhopadhyay D, Deloche O, Wanke V, Anrather D, Ammerer G, Riezman H, Broach JR, De Virgilio C, Hall MN, Loewith R (2007) Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Mol Cell 26, 663-674.
-
(2007)
Mol Cell
, vol.26
, pp. 663-674
-
-
Urban, J.1
Soulard, A.2
Huber, A.3
Lippman, S.4
Mukhopadhyay, D.5
Deloche, O.6
Wanke, V.7
Anrather, D.8
Ammerer, G.9
Riezman, H.10
Broach, J.R.11
De Virgilio, C.12
Hall, M.N.13
Loewith, R.14
-
51
-
-
0642367846
-
Genetics: Influence of TOR kinase on lifespan in C. elegans
-
Vellai T, Takacs-Vellai K, Zhang Y, Kovacs AL, Orosz L, Muller F (2003) Genetics: Influence of TOR kinase on lifespan in C. elegans. Nature 426, 620.
-
(2003)
Nature
, vol.426
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.L.4
Orosz, L.5
Muller, F.6
-
53
-
-
38949137849
-
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
-
Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, Longo VD (2008) Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9. PLoS Genet. 4, e13.
-
(2008)
PLoS Genet.
, vol.4
-
-
Wei, M.1
Fabrizio, P.2
Hu, J.3
Ge, H.4
Cheng, C.5
Li, L.6
Longo, V.D.7
-
54
-
-
38849122572
-
Incorporating molecular tools into early-stage clinical trials
-
Weil RJ (2008) Incorporating molecular tools into early-stage clinical trials. PLoS Med. 5, e21.
-
(2008)
PLoS Med.
, vol.5
-
-
Weil, R.J.1
-
55
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN (2006) TOR signaling in growth and metabolism. Cell 124, 471-484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
56
-
-
41149154473
-
Pathways change in expression during replicative aging in Saccharomyces cerevisiae
-
Yiu G, McCord A, Wise A, Jindal R, Hardee J, Kuo A, Shimogawa MY, Cahoon L, Wu M, Kloke J, Hardin J, Mays Hoopes LL (2008) Pathways change in expression during replicative aging in Saccharomyces cerevisiae. J. Gerontol. A Biol. Sci. Med. Sci. 63, 21-34.
-
(2008)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.63
, pp. 21-34
-
-
Yiu, G.1
McCord, A.2
Wise, A.3
Jindal, R.4
Hardee, J.5
Kuo, A.6
Shimogawa, M.Y.7
Cahoon, L.8
Wu, M.9
Kloke, J.10
Hardin, J.11
Mays Hoopes, L.L.12
|