메뉴 건너뛰기




Volumn 31, Issue 1, 2009, Pages 1-11

Formulations for delivery of therapeutic proteins

Author keywords

Drug delivery; Intracellular delivery; Non invasive; Protein delivery; Sustained release

Indexed keywords

DRUG DELIVERY; TRANSLATION (LANGUAGES);

EID: 56649103707     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-008-9834-y     Document Type: Review
Times cited : (48)

References (77)
  • 3
    • 33344467489 scopus 로고    scopus 로고
    • Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system
    • M Amidi W Jiskoot 2006 Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system J Control Release 111 107 116
    • (2006) J Control Release , vol.111 , pp. 107-116
    • Amidi, M.1    Jiskoot, W.2
  • 6
    • 26644452975 scopus 로고    scopus 로고
    • Thiomers: A new generation of mucoadhesive polymers
    • A Bernkop-Schnurch 2005 Thiomers: a new generation of mucoadhesive polymers Adv Drug Deliv Rev 57 569 1582
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 569-1582
    • Bernkop-Schnurch, A.1
  • 8
    • 44449128659 scopus 로고    scopus 로고
    • GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier
    • RJ Boado Y Zhang Y Wang WM Pardridge 2008 GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier Biotechnol Bioeng 100 387 396
    • (2008) Biotechnol Bioeng , vol.100 , pp. 387-396
    • Boado, R.J.1    Zhang, Y.2    Wang, Y.3    Pardridge, W.M.4
  • 9
    • 27744516079 scopus 로고    scopus 로고
    • Insulin particles formation in supersaturated aqueous solution of poly(ethylene glycol)
    • L Bromerg J Rashba-Step T Scott 2005 Insulin particles formation in supersaturated aqueous solution of poly(ethylene glycol) Biophys J 89 3424 3433
    • (2005) Biophys J , vol.89 , pp. 3424-3433
    • Bromerg, L.1    Rashba-Step, J.2    Scott, T.3
  • 10
    • 13844256698 scopus 로고    scopus 로고
    • Tat peptide-mediated cellular delivery: Back to basics
    • H Brooks B Lebleu E Vives 2005 Tat peptide-mediated cellular delivery: back to basics Adv Drug Deliv Rev 57 559 577
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 559-577
    • Brooks, H.1    Lebleu, B.2    Vives, E.3
  • 11
    • 12344281758 scopus 로고    scopus 로고
    • Commercial challenges of protein drug delivery
    • LR Brown 2005 Commercial challenges of protein drug delivery Expert Opin Drug Deliv 2 29 42
    • (2005) Expert Opin Drug Deliv , vol.2 , pp. 29-42
    • Brown, L.R.1
  • 12
    • 0344420226 scopus 로고    scopus 로고
    • Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates
    • P Caliceti FM Veronese 2003 Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates Adv Drug Deliv Rev 55 1261 1277
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 1261-1277
    • Caliceti, P.1    Veronese, F.M.2
  • 13
    • 44749094651 scopus 로고    scopus 로고
    • Evaluation of direct transport pathways of glycine receptor antagonists and an angiotensin antagonist from the nasal cavity to the central nervous system in the rat model
    • S Charlton J Whetstone S Fayinka K Read L Illum SS Davis 2008 Evaluation of direct transport pathways of glycine receptor antagonists and an angiotensin antagonist from the nasal cavity to the central nervous system in the rat model Pharm Res 25 1531 1543
    • (2008) Pharm Res , vol.25 , pp. 1531-1543
    • Charlton, S.1    Whetstone, J.2    Fayinka, S.3    Read, K.4    Illum, L.5    Davis, S.S.6
  • 15
    • 34547219515 scopus 로고    scopus 로고
    • Periodontal regeneration using novel glycidyl methacrylated dextran (Dex-GMA)/gelatin scaffolds containing microspheres loaded with bone morphogenetic proteins
    • F-M Chen Y-M Zhao R Zhang T Jin H-H Sun Z-F Wu Y Jin 2007 Periodontal regeneration using novel glycidyl methacrylated dextran (Dex-GMA)/gelatin scaffolds containing microspheres loaded with bone morphogenetic proteins J Control Release 121 81 90
    • (2007) J Control Release , vol.121 , pp. 81-90
    • Chen, F.-M.1    Zhao, Y.-M.2    Zhang, R.3    Jin, T.4    Sun, H.-H.5    Wu, Z.-F.6    Jin, Y.7
  • 17
    • 33845945920 scopus 로고    scopus 로고
    • Biodegradable injectable in situ depot-forming drug delivery systems
    • D Chitkara A Shikanov N Kumar AJ Domb 2006 Biodegradable injectable in situ depot-forming drug delivery systems Macromol Biosci 6 977 990
    • (2006) Macromol Biosci , vol.6 , pp. 977-990
    • Chitkara, D.1    Shikanov, A.2    Kumar, N.3    Domb, A.J.4
  • 18
    • 3042852733 scopus 로고    scopus 로고
    • Intracytoplasmic delivery of anionic proteins
    • D Dalkara G Zuber JP Behr 2004 Intracytoplasmic delivery of anionic proteins Mol Ther 9 964 969
    • (2004) Mol Ther , vol.9 , pp. 964-969
    • Dalkara, D.1    Zuber, G.2    Behr, J.P.3
  • 19
    • 47949132524 scopus 로고    scopus 로고
    • Surface modification of microspheres with steric stabilising and cationic polymers for gene delivery
    • OR Davies L Head D Armitage EA Pearson MC Davies M Marlow S Stolnik 2008 Surface modification of microspheres with steric stabilising and cationic polymers for gene delivery Langmuir 24 7138 7146
    • (2008) Langmuir , vol.24 , pp. 7138-7146
    • Davies, O.R.1    Head, L.2    Armitage, D.3    Pearson, E.A.4    Davies, M.C.5    Marlow, M.6    Stolnik, S.7
  • 20
    • 47949108551 scopus 로고    scopus 로고
    • Macroporous surface modified microparticles
    • 10.1039/b805421e
    • OR Davies M Marlow S Stolnik 2008 Macroporous surface modified microparticles Soft Matter 10.1039/b805421e
    • (2008) Soft Matter
    • Davies, O.R.1    Marlow, M.2    Stolnik, S.3
  • 21
    • 34347387938 scopus 로고    scopus 로고
    • Strategies to improve drug delivery across the blood-brain barrier
    • AG de Boer PJ Gaillard 2007 Strategies to improve drug delivery across the blood-brain barrier Clin Pharmacokinet 46 553 576
    • (2007) Clin Pharmacokinet , vol.46 , pp. 553-576
    • De Boer, A.G.1    Gaillard, P.J.2
  • 22
    • 12244309511 scopus 로고    scopus 로고
    • Smart polymeric carriers for enhanced intracellular delivery of therapeutic macromolecules
    • MEH El-Sayed AS Hoffman PS Stayton 2005 Smart polymeric carriers for enhanced intracellular delivery of therapeutic macromolecules Expert Opin Biol Ther 5 23 32
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 23-32
    • El-Sayed, M.E.H.1    Hoffman, A.S.2    Stayton, P.S.3
  • 23
    • 34547655840 scopus 로고    scopus 로고
    • Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration
    • X Gao B Wu Q Zhang J Chen J Zhu W Zhang Z Rong H Chen X Jiang 2007 Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration J Control Release 121 156 167
    • (2007) J Control Release , vol.121 , pp. 156-167
    • Gao, X.1    Wu, B.2    Zhang, Q.3    Chen, J.4    Zhu, J.5    Zhang, W.6    Rong, Z.7    Chen, H.8    Jiang, X.9
  • 26
    • 0031398518 scopus 로고    scopus 로고
    • Lectins and bacterial invasion factors for controlling endo- and trancytosis of bioadhesive drug delivery systems
    • E Haltner JH Easson CM Lehr 1997 Lectins and bacterial invasion factors for controlling endo- and trancytosis of bioadhesive drug delivery systems Eur J Pharm Biopharm 44 3 13
    • (1997) Eur J Pharm Biopharm , vol.44 , pp. 3-13
    • Haltner, E.1    Easson, J.H.2    Lehr, C.M.3
  • 27
    • 1042269557 scopus 로고    scopus 로고
    • Is nose-to-brain transport of drugs in man a reality?
    • L Illum 2004 Is nose-to-brain transport of drugs in man a reality? J Pharm Pharmacol 56 3 17
    • (2004) J Pharm Pharmacol , vol.56 , pp. 3-17
    • Illum, L.1
  • 28
    • 33846441633 scopus 로고    scopus 로고
    • Anti-inflammatory function of an in situ cross-linkable conjugate hydrogel of hyaluronic acid and dexamethasone
    • T Ito IP Fraserb Y Yeoa CB Highleya E Bellasa DS Kohane 2007 Anti-inflammatory function of an in situ cross-linkable conjugate hydrogel of hyaluronic acid and dexamethasone Biomaterials 28 1778 1786
    • (2007) Biomaterials , vol.28 , pp. 1778-1786
    • Ito, T.1    Fraserb, I.P.2    Yeoa, Y.3    Highleya, C.B.4    Bellasa, E.5    Kohane, D.S.6
  • 29
    • 35548961942 scopus 로고    scopus 로고
    • Novel scaffolds fabricated from protein-loaded microspheres for tissue engineering
    • A Jaklenec E Wan ME Murray E Mathiowitz 2008 Novel scaffolds fabricated from protein-loaded microspheres for tissue engineering Biomaterials 29 185 192
    • (2008) Biomaterials , vol.29 , pp. 185-192
    • Jaklenec, A.1    Wan, E.2    Murray, M.E.3    Mathiowitz, E.4
  • 30
    • 0034750040 scopus 로고    scopus 로고
    • Diamonds in the rough: Protein crystals from a formulation perspective
    • A Jen HP Merkle 2001 Diamonds in the rough: protein crystals from a formulation perspective Pharm Res 18 1483 1488
    • (2001) Pharm Res , vol.18 , pp. 1483-1488
    • Jen, A.1    Merkle, H.P.2
  • 31
    • 1142309545 scopus 로고    scopus 로고
    • M cell targeting by lectins: A strategy for mucosal vaccination and drug delivery
    • MA Jepson MA Clark BH Hirst 2004 M cell targeting by lectins: a strategy for mucosal vaccination and drug delivery Adv Drug Deliv Rev 56 511 525
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 511-525
    • Jepson, M.A.1    Clark, M.A.2    Hirst, B.H.3
  • 32
    • 11044223222 scopus 로고    scopus 로고
    • Liposome-based depot injection technologies how versatile are they?
    • NV Katre 2004 Liposome-based depot injection technologies how versatile are they? Am J Drug Deliv 4 213 227
    • (2004) Am J Drug Deliv , vol.4 , pp. 213-227
    • Katre, N.V.1
  • 33
    • 0037161330 scopus 로고    scopus 로고
    • Temperature-responsive and degradable hyaluronic acid/Pluronic composite hydrogels for controlled release of human growth hormone
    • MR Kim TG Park 2002 Temperature-responsive and degradable hyaluronic acid/Pluronic composite hydrogels for controlled release of human growth hormone J Control Release 80 69 77
    • (2002) J Control Release , vol.80 , pp. 69-77
    • Kim, M.R.1    Park, T.G.2
  • 34
    • 35449006733 scopus 로고    scopus 로고
    • Tight junction modulators: Promising candidates for drug delivery
    • M Kondoh K Yagi 2007 Tight junction modulators: promising candidates for drug delivery Med Chem 14 2482 2488
    • (2007) Med Chem , vol.14 , pp. 2482-2488
    • Kondoh, M.1    Yagi, K.2
  • 35
    • 33748363100 scopus 로고    scopus 로고
    • A novel strategy for a drug delivery system using a claudin modulator
    • M Kondoh A Takahashi M Fujii K Yagi Y Watanabe 2006 A novel strategy for a drug delivery system using a claudin modulator Biol Pharm Bull 29 1783 1789
    • (2006) Biol Pharm Bull , vol.29 , pp. 1783-1789
    • Kondoh, M.1    Takahashi, A.2    Fujii, M.3    Yagi, K.4    Watanabe, Y.5
  • 36
    • 33846859117 scopus 로고    scopus 로고
    • A novel in situ forming drug delivery system for controlled parenteral drug delivery
    • H Kranz R Bodmeier 2007 A novel in situ forming drug delivery system for controlled parenteral drug delivery Int J Pharm 332 107 114
    • (2007) Int J Pharm , vol.332 , pp. 107-114
    • Kranz, H.1    Bodmeier, R.2
  • 37
    • 29244473159 scopus 로고    scopus 로고
    • Thiolated chitosan microparticles: A vehicle for nasal peptide drug delivery
    • AH Krauland AB Schnurch 2006 Thiolated chitosan microparticles: a vehicle for nasal peptide drug delivery Int J Pharm 307 270 277
    • (2006) Int J Pharm , vol.307 , pp. 270-277
    • Krauland, A.H.1    Schnurch, A.B.2
  • 38
    • 2442672006 scopus 로고    scopus 로고
    • Insulin microcrystal suspension as a long-acting formulation for pulmonary delivery
    • J-H Kwon B-H Lee J-J Lee C-W Kim 2004 Insulin microcrystal suspension as a long-acting formulation for pulmonary delivery Eur J Pharm Sci 22 107 116
    • (2004) Eur J Pharm Sci , vol.22 , pp. 107-116
    • Kwon, J.-H.1    Lee, B.-H.2    Lee, J.-J.3    Kim, C.-W.4
  • 39
    • 0033813758 scopus 로고    scopus 로고
    • Bioadhesive-based dosage forms: The next generation
    • JW Lee JH Park JR Robinson 2000 Bioadhesive-based dosage forms: the next generation J Pharm Sci 89 850 866
    • (2000) J Pharm Sci , vol.89 , pp. 850-866
    • Lee, J.W.1    Park, J.H.2    Robinson, J.R.3
  • 40
    • 38349076002 scopus 로고    scopus 로고
    • Efficient intracellular delivery of functional proteins using cationic polymer core/shell nanoparticles
    • AL Lee Y Wang W-H Ye HS Yoon SY Chan Y-Y Yang 2008 Efficient intracellular delivery of functional proteins using cationic polymer core/shell nanoparticles Biomaterials 29 1224 1232
    • (2008) Biomaterials , vol.29 , pp. 1224-1232
    • Lee, A.L.1    Wang, Y.2    Ye, W.-H.3    Yoon, H.S.4    Chan, S.Y.5    Yang, Y.-Y.6
  • 41
    • 7444254865 scopus 로고    scopus 로고
    • Nasal delivery of human growth hormone: In vitro and in vivo evaluation of thiomer/glutathione microparticulate delivery system
    • VM Leitner AB Schnurch 2004 Nasal delivery of human growth hormone: in vitro and in vivo evaluation of thiomer/glutathione microparticulate delivery system J Control Release 100 87 95
    • (2004) J Control Release , vol.100 , pp. 87-95
    • Leitner, V.M.1    Schnurch, A.B.2
  • 42
    • 0036238011 scopus 로고    scopus 로고
    • Transferrin/transferrin receptor-mediated drug delivery
    • H Li ZM Qian 2002 Transferrin/transferrin receptor-mediated drug delivery Med Res Rev 22 225 250
    • (2002) Med Res Rev , vol.22 , pp. 225-250
    • Li, H.1    Qian, Z.M.2
  • 43
    • 33751195735 scopus 로고    scopus 로고
    • Hydrogels in controlled release formulations: Network design and mathematical modeling
    • CC Lin A Metters 2006 Hydrogels in controlled release formulations: network design and mathematical modeling Adv Drug Deliv Rev 58 1379 1408
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1379-1408
    • Lin, C.C.1    Metters, A.2
  • 45
    • 0042236986 scopus 로고    scopus 로고
    • HIV TAT protein transduction domain mediated cell binding and intracellular delivery of nanoparticles
    • JA MacKay FC Szoka Jr 2003 HIV TAT protein transduction domain mediated cell binding and intracellular delivery of nanoparticles J Dispers Sci Technol 24 465 473
    • (2003) J Dispers Sci Technol , vol.24 , pp. 465-473
    • MacKay, J.A.1    Szoka Jr., F.C.2
  • 46
    • 29244468833 scopus 로고    scopus 로고
    • Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells
    • S Mao O Germershaus D Fischer T Linn R Schnepf T Kissel 2005 Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells Pharm Res 22 2058 2068
    • (2005) Pharm Res , vol.22 , pp. 2058-2068
    • Mao, S.1    Germershaus, O.2    Fischer, D.3    Linn, T.4    Schnepf, R.5    Kissel, T.6
  • 47
    • 41849105252 scopus 로고    scopus 로고
    • Lipid-based colloidal carriers for peptide and protein delivery-liposomes versus lipid nanoparticles
    • S Martins B Sarmento D Ferreira 2007 Lipid-based colloidal carriers for peptide and protein delivery-liposomes versus lipid nanoparticles Int J Nanomed 2 595 607
    • (2007) Int J Nanomed , vol.2 , pp. 595-607
    • Martins, S.1    Sarmento, B.2    Ferreira, D.3
  • 48
    • 0035845757 scopus 로고    scopus 로고
    • Effect of poly-arginine on the nasal absorption of FITC-dextran of different molecular weights and recombinant human granulocyte colony-stimulating factor (rhG-CSF) in rats
    • M Miyamoto H Natsume I Satoh K Ohtake M Yamaguchi D Kobayashi K Sugibayashi Y Morimoto 2001 Effect of poly-arginine on the nasal absorption of FITC-dextran of different molecular weights and recombinant human granulocyte colony-stimulating factor (rhG-CSF) in rats Int J Pharm 226 127 138
    • (2001) Int J Pharm , vol.226 , pp. 127-138
    • Miyamoto, M.1    Natsume, H.2    Satoh, I.3    Ohtake, K.4    Yamaguchi, M.5    Kobayashi, D.6    Sugibayashi, K.7    Morimoto, Y.8
  • 49
    • 2442672527 scopus 로고    scopus 로고
    • Calcium phosphate-PEG-insulin-casein (CAPIC) particles as oral delivery systems for insulin
    • T Morçöl P Nagappan L Nerenbaum A Mitchell SJD Bell 2004 Calcium phosphate-PEG-insulin-casein (CAPIC) particles as oral delivery systems for insulin Int J Pharm 277 91 97
    • (2004) Int J Pharm , vol.277 , pp. 91-97
    • Morçöl, T.1    Nagappan, P.2    Nerenbaum, L.3    Mitchell, A.4    Bell, S.J.D.5
  • 50
    • 33748752402 scopus 로고    scopus 로고
    • Is the oral route possible for peptide and protein drug delivery?
    • M Morishita NA Peppas 2006 Is the oral route possible for peptide and protein drug delivery? Drug Discov Today 11 905 910
    • (2006) Drug Discov Today , vol.11 , pp. 905-910
    • Morishita, M.1    Peppas, N.A.2
  • 51
    • 0036955764 scopus 로고    scopus 로고
    • Intracellular drug delivery using poly(d, l-lactide-co-glycolide) nanoparticles derivatized with a peptide from a transcriptional activator protein of HIV-1
    • YS Nam JY Park S-H Han I-S Chang 2002 Intracellular drug delivery using poly(d, l-lactide-co-glycolide) nanoparticles derivatized with a peptide from a transcriptional activator protein of HIV-1 Biotechnol Lett 24 2093 2098
    • (2002) Biotechnol Lett , vol.24 , pp. 2093-2098
    • Nam, Y.S.1    Park, J.Y.2    Han, S.-H.3    Chang, I.-S.4
  • 53
    • 56649102842 scopus 로고    scopus 로고
    • Certolizumab pegol adalimumab accumulation in the inflammed paws of mice with collagen-induced arthritis compared to noninflammed tissue in vivo biofluorescence imaging of Alexa 680-labeled antibodies
    • R Palframan A Vugler A Moore M Baker D Lightwood A Nesbitt R Foulkes N Gozzard 2007 Certolizumab pegol adalimumab accumulation in the inflammed paws of mice with collagen-induced arthritis compared to noninflammed tissue in vivo biofluorescence imaging of Alexa 680-labeled antibodies Clin Immunol 123 S170
    • (2007) Clin Immunol , vol.123 , pp. 170
    • Palframan, R.1    Vugler, A.2    Moore, A.3    Baker, M.4    Lightwood, D.5    Nesbitt, A.6    Foulkes, R.7    Gozzard, N.8
  • 54
    • 34548650086 scopus 로고    scopus 로고
    • Blood-brain barrier delivery of protein and non-viral gene therapeutics with molecular Trojan horses
    • WM Pardridge 2007 Blood-brain barrier delivery of protein and non-viral gene therapeutics with molecular Trojan horses J Control Release 122 345 348
    • (2007) J Control Release , vol.122 , pp. 345-348
    • Pardridge, W.M.1
  • 55
    • 33644749440 scopus 로고    scopus 로고
    • Stimuli-sensitive protein delivery systems
    • NA Peppas B Kim 2006 Stimuli-sensitive protein delivery systems J Drug Deliv Sci Technol 16 11 18
    • (2006) J Drug Deliv Sci Technol , vol.16 , pp. 11-18
    • Peppas, N.A.1    Kim, B.2
  • 56
    • 84875806479 scopus 로고    scopus 로고
    • Cited July 29, 2008
    • Pharma Circle, Online database: http://www.pharmacircle.com. Cited July 29, 2008
    • Online Database
  • 57
    • 0030026226 scopus 로고    scopus 로고
    • Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue
    • W Rubas ME Cromwell Z Shahrokh 1996 Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue J Pharm Sci 85 165 169
    • (1996) J Pharm Sci , vol.85 , pp. 165-169
    • Rubas, W.1    Cromwell, M.E.2    Shahrokh, Z.3
  • 58
    • 34250665873 scopus 로고    scopus 로고
    • Targeted delivery of proteins across the blood-brain barrier
    • BJ Spencer IM Verma 2007 Targeted delivery of proteins across the blood-brain barrier Proc Natl Acad Sci USA 18 7594 7599
    • (2007) Proc Natl Acad Sci USA , vol.18 , pp. 7594-7599
    • Spencer, B.J.1    Verma, I.M.2
  • 59
    • 0029360711 scopus 로고
    • Long circulating microparticulate drug carriers
    • S Stolnik L Illum SS Davis 1995 Long circulating microparticulate drug carriers Adv Drug Deliv Rev 16 195 214
    • (1995) Adv Drug Deliv Rev , vol.16 , pp. 195-214
    • Stolnik, S.1    Illum, L.2    Davis, S.S.3
  • 61
    • 28244466864 scopus 로고    scopus 로고
    • Complement activation-related pseudoallergy: A new class of drug-induced acute immune toxicity
    • J Szebeni 2005 Complement activation-related pseudoallergy: a new class of drug-induced acute immune toxicity Toxicology 216 106 121
    • (2005) Toxicology , vol.216 , pp. 106-121
    • Szebeni, J.1
  • 62
    • 0035937594 scopus 로고    scopus 로고
    • Mucoadhesive nanoparticulate systems for peptide drug delivery
    • H Takeuchi H Yamamoto Y Kawashima 2001 Mucoadhesive nanoparticulate systems for peptide drug delivery Adv Drug Deliv Rev 47 39 54
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 39-54
    • Takeuchi, H.1    Yamamoto, H.2    Kawashima, Y.3
  • 63
    • 34249951300 scopus 로고    scopus 로고
    • Matrices and scaffolds for protein delivery in tissue engineering
    • JK Tessmar AM Goepferich 2007 Matrices and scaffolds for protein delivery in tissue engineering Adv Drug Deliv Rev 59 274 291
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 274-291
    • Tessmar, J.K.1    Goepferich, A.M.2
  • 64
    • 36248956678 scopus 로고    scopus 로고
    • Designing lipid nanostructures for local delivery of biologically active macromolecules
    • M Trif A Roseanu JH Brock JM Brewer 2007 Designing lipid nanostructures for local delivery of biologically active macromolecules J Liposome Res 17 237 248
    • (2007) J Liposome Res , vol.17 , pp. 237-248
    • Trif, M.1    Roseanu, A.2    Brock, J.H.3    Brewer, J.M.4
  • 65
    • 52449102429 scopus 로고    scopus 로고
    • Complexation hydrogels for oral insulin delivery: Effects of polymer dosing on in vivo efficacy
    • A Tuesca K Nakamura M Morishita J Joseph N Peppas A Lowman 2007 Complexation hydrogels for oral insulin delivery: effects of polymer dosing on in vivo efficacy J Pharm Sci 97 2607 2618
    • (2007) J Pharm Sci , vol.97 , pp. 2607-2618
    • Tuesca, A.1    Nakamura, K.2    Morishita, M.3    Joseph, J.4    Peppas, N.5    Lowman, A.6
  • 66
    • 0037817352 scopus 로고    scopus 로고
    • Transcytosis: Crossing cellular barriers
    • PL Tuma AL Hubbard 2003 Transcytosis: crossing cellular barriers Physiol Rev 83 871 932
    • (2003) Physiol Rev , vol.83 , pp. 871-932
    • Tuma, P.L.1    Hubbard, A.L.2
  • 67
    • 33745265629 scopus 로고    scopus 로고
    • Microsphere-integrated collagen scaffolds for tissue engineering: Effect of microsphere formulation and scaffold properties on protein release kinetics
    • F Ungaro M Biondi I d'Angelo L Indolfi F Quaglia PA Netti MI La Rotonda 2006 Microsphere-integrated collagen scaffolds for tissue engineering: effect of microsphere formulation and scaffold properties on protein release kinetics J Control Release 113 128 136
    • (2006) J Control Release , vol.113 , pp. 128-136
    • Ungaro, F.1    Biondi, M.2    D'Angelo, I.3    Indolfi, L.4    Quaglia, F.5    Netti, P.A.6    La Rotonda, M.I.7
  • 68
    • 34047142727 scopus 로고    scopus 로고
    • Biodegradable dextran hydrogels for protein delivery applications
    • SR Van Tomme WE Hennink 2007 Biodegradable dextran hydrogels for protein delivery applications Expert Rev Med Devices 4 147 164
    • (2007) Expert Rev Med Devices , vol.4 , pp. 147-164
    • Van Tomme, S.R.1    Hennink, W.E.2
  • 69
    • 3242717735 scopus 로고    scopus 로고
    • Transport of PLA-PEG particles across the nasal mucosa: Effect of particle size and PEG coating density
    • A Vila H Gill O McCallion MJ Alonso 2004 Transport of PLA-PEG particles across the nasal mucosa: effect of particle size and PEG coating density J Control Release 98 231 244
    • (2004) J Control Release , vol.98 , pp. 231-244
    • Vila, A.1    Gill, H.2    McCallion, O.3    Alonso, M.J.4
  • 70
    • 13844256697 scopus 로고    scopus 로고
    • Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer
    • JS Wadia SF Dowdy 2005 Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer Adv Drug Deliv Rev 57 579 596
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 579-596
    • Wadia, J.S.1    Dowdy, S.F.2
  • 71
    • 33646525645 scopus 로고    scopus 로고
    • Protein transduction: Cell penetrating peptides and their therapeutic applications
    • KM Wagstaff DA Jans 2006 Protein transduction: cell penetrating peptides and their therapeutic applications Curr Med Chem 13 1371 1387
    • (2006) Curr Med Chem , vol.13 , pp. 1371-1387
    • Wagstaff, K.M.1    Jans, D.A.2
  • 72
    • 33846657400 scopus 로고    scopus 로고
    • The enhancement of osteogenesis by nano-fibrous scaffolds incorporating rhBMP-7 nanospheres
    • G Wei Q Jin WV Giannobile PX Ma 2007 The enhancement of osteogenesis by nano-fibrous scaffolds incorporating rhBMP-7 nanospheres Biomaterials 28 2087 2096
    • (2007) Biomaterials , vol.28 , pp. 2087-2096
    • Wei, G.1    Jin, Q.2    Giannobile, W.V.3    Ma, P.X.4
  • 75
    • 0035068551 scopus 로고    scopus 로고
    • Bioadhesion: New possibilities for drug administration?
    • J Woodley 2001 Bioadhesion: new possibilities for drug administration? Clin Pharmacokinet 40 77 84
    • (2001) Clin Pharmacokinet , vol.40 , pp. 77-84
    • Woodley, J.1
  • 76
    • 56649119636 scopus 로고    scopus 로고
    • Spherical protein particles and methods for making and using them
    • US Patent 2004/0219224A1
    • Yakovlevski K (2004) Spherical protein particles and methods for making and using them, US Patent 2004/0219224A1
    • (2004)
    • Yakovlevski, K.1
  • 77
    • 38949111716 scopus 로고    scopus 로고
    • PLGA nanoparticle-peptide conjugate effectively targets intercellular cell-adhesion molecule-1
    • N Zhang C Chittasupho C Duangrat T Siahaan C Berkland 2008 PLGA nanoparticle-peptide conjugate effectively targets intercellular cell-adhesion molecule-1 Bioconjug Chem 19 145 152
    • (2008) Bioconjug Chem , vol.19 , pp. 145-152
    • Zhang, N.1    Chittasupho, C.2    Duangrat, C.3    Siahaan, T.4    Berkland, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.