Surface modification of microspheres with steric stabilizing and cationic polymers for gene delivery

Langmuir

Volumn 24, Issue 14, 2008, Pages 7138-7146

  Davies, Owen R ^b   Head, Laura ^b   Armitage, David ^b   Pearson, Elizabeth A ^b   Davies, Martin C ^b   Marlow, Maria ^b   Stolnik, Snjezana ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMERICAN CHEMICAL SOCIETY (ACS); CATIONIC POLYMERS; COLLOIDAL STABILITY; CONCENTRATION (COMPOSITION); DNA SURFACES; DNA VACCINES; DNA-BINDING; ENZYMATIC DEGRADATION; ETHYL METHACRYLATE (PEMA); GENE DELIVERY; IN-VIVO; NEGATIVE POTENTIALS; OIL IN WATER (O/W); OPTIMIZED CONDITIONS; POLY CATIONS; POLY L LYSINE (PLL); POLY(D ,L-LACTIDE-CO-GLYCOLIDE); POLYCATIONS (PC); POLYVINYL ALCOHOL (PVOL); PRODUCTION VARIABLES; SOLVENT EVAPORATION METHODS; SURFACE MODIFICATIONS; SYSTEMATIC EVALUATION; TARGET CELLS; TRIMETHYL CHITOSAN; WATER PHASE;

AMINES; AMINO ACIDS; CELL CULTURE; CONCENTRATION (PROCESS); CURVE FITTING; CYTOTOXICITY; DNA; GENE TRANSFER; GENES; INTERNET; LEAD; MICROSPHERES; NUCLEIC ACIDS; OPTICAL DESIGN; ORGANIC ACIDS; ORGANIC POLYMERS; POLYMER BLENDS; SULFATE MINERALS; SURFACE TREATMENT; SYSTEM STABILITY; VACCINES;

AGGLOMERATION;

BUFFER; CATION; DNA; MICROSPHERE; POLYMER;

ADSORPTION; ARTICLE; CELL LINE; CHEMISTRY; COLLOID; GENE TRANSFER; HUMAN; MOLECULAR WEIGHT; PARTICLE SIZE; PLASMID; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

ADSORPTION; BUFFERS; CATIONS; CELL LINE; COLLOIDS; DNA; GENE TRANSFER TECHNIQUES; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR WEIGHT; PARTICLE SIZE; PLASMIDS; POLYMERS; SURFACE PROPERTIES;

EID: 47949132524     PISSN: 07437463     EISSN: None     Source Type: Journal    
DOI: 10.1021/la703735n     Document Type: Article

References (33)

1. Capan, Y.; Woo, B. H.; Gebrekidan, S.; Ahmed, S.; DeLuca, P. P. Pharm. Res. 1999, 16(4), 509-513.
2. Chen, S. C.; Jones, D. H.; Fynan, E. F.; Farrar, G. H.; Clegg, J. C. S.; Greenberg, H. B.; Herrmann, J. E. J. Virol. 1998, 72(7), 5757-5761.
3. Jones, D. H.; Corns, S.; McDonald, S.; Clegg, J. C. S.; Farrar, G. H. Vaccine 1997, 15(8), 814-817.
4. McKeever, U.; Barman, S.; Hao, T.; Chambers, P.; Song, S.; Lunsford, L.; Hsu, Y. Y.; Roy, K.; Hedley, M. L. Vaccine 2002, 20(11-12), 1524-1531.
5. Singh, M.; Briones, M.; Ott, G.; O'Hagan, D. Proc. Natl Acad. Sci. U.S.A. 2000, 97(2), 811-816.
6. Singh, M.; Vajdy, M.; Gardner, J.; Briones, M.; O'Hagan, D. Vaccine 2001, 20(3-4), 594-602.
7. Wang, D. Q.; Robinson, D. R.; Kwon, G. S.; Samuel, J. J. Controlled Release 1999, 57(1), 9-18.
8. Fu, K.; Pack, D. W.; Klibanov, A. M.; Langer, R. Pharm. Res. 2000, 17(1), 100-106.
9. Cui, Z. R.; Mumper, R. J. J. Pharm. Pharmacol. 2002, 54(9), 1195-1203.
10. Manuel, W. S.; Zheng, J.; Hornsby, P. J. J. Drug Targeting 2001, 9(1), 15+
11. Maruyama, A.; Ishihara, T.; Kim, J. S.; Kim, S.W.; Akaike, T. Bioconjugate Chem. 1997, 8(5), 735-742.
12. Walter, E.; Merkle, H. P. J. Drug Targeting 2002, 10(1), 11-21.
13. Bivas-Benita, M.; Romeijn, S.; Junginger, H. E.; Borchard, G. Eur. J. Pharm. Biopharm. 2004, 58(1), 1-6.
14. Weigele, M.; Debernar, S; Leimgrub, W Biochem. Biophys. Res. Commun. 1973, 50(2), 352-356.
15. Godbey, W. T.; Wu, K. K.; Mikos, A. G. Proc. Natl Acad. Sci. U.S.A. 1999, 96(9), 5177-5181.
16. Ogris, M.; Wagner, E.; Steinlein. P. Biochim. Biophys. Acta 2000, 1474(2), 237-243.
17. Scholes, P. D.; Coombes, A. G. A.; Ilium, L.; Davis, S. S.; Watts, J. F.; Ustariz, C.; Vert, M.; Davies, M. C. J. Controlled Release 1999, 59(3), 261-278.
18. De Rosa, G.; Quaglia, F.; La Rotonda, M. I.; Appel, M.; Alphandary, H.; Fattal, E. J. Pharm. Sci. 2002, 91(3), 790-799.
19. Meszaros, R.; Thompson, L.; Bos, M.; de Groot, P. Langmuir 2002, 18(16), 6164-6169.
20. Schneider, M.; Brinkmann, M.; Mohwald, H. Macromolecules 2003, 36(25), 9510-9518.
21. Kumar, M.; Bakowsky, U.; Lehr, C. M. Biomaterials 2004, 25(10), 1771-1777.
22. Petersen, H.; Kunath, K.; Martin, A. L.; Stolnik, S.; Roberts, C. J.; Davies, M. C.; Kissel, T. Biomacromolecules 2002, 3(5), 926-936.
23. Hesselink, F. T. J. Colloid Interface Sci. 1977, 60(3), 448-466.
24. Chodanowski. P.; Stoll, S. J. Chem. Phys. 2001, 115(10), 4951-4960.
25. Stolnik. S; Garnett, M. C.; Davies, M. C.; Ilium, L.; Bousta, M.; Vert, M.; Davis, S. S. Colloids Surf., A: Physicochem. Eng. Aspects 1995, 97, 235-245.
26. Lyklema, J.; Fleer, G. J. Colloids Surf. 1987, 25(2-4), 357-368.
27. Fleer,. G. J.; Cohen Stuart, A.; Scheutjens, J. M. H. M.; Cosgrove, T.; Vincent, B. Polymers at Interfaces; Chapman and Hall: London, UK, 1993.
28. Gotting, N.; Fritz, H.; Maier, M.; von Stamm, J.; Schoofs, T.; Bayer, E. Colloid Polym. Sci. 1999, 277(2-3), 145-152.
29. Chim, Y. T. A.; Lam, J. K. W.; Ma, Y.; Armes, S. P.; Lewis, A. L.; Roberts, C. J.; Stolnik, S.; Tendler, S. J. B.; Davies, M. C. Langmuir 2005, 21, 3591-3598.
30. Klan, N; Steinhilber, D. Biotechniques 2003, 34, 142-7.
31. Walter, E: Merkle, H. P. J. Drug Targeting 2002, 10, 11-21.
32. Denis-Mize, K. S.; Dupuis, M.; MacKichan, M. L.; Singh, M.; Doe, B.; O'Hagan, D.; Ulmer, J. B.; Donnelly, J. J.; McDonald, D. M.; Ott, G. Gene Ther. 2000, 7, 2105-2112.
33. Foged, C.; Brodin, B.; Frokjaer, S.; Sundblad, A. Int. J. Pharm. 2005, 298, 315-322.