-
1
-
-
17644396349
-
Immunology of multiple sclerosis
-
Sospedra M., and Martin R. Immunology of multiple sclerosis. Annu Rev Immunol 23 (2005) 683-747
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
2
-
-
0017109389
-
B-lymphocyte alloantigens associated with multiple sclerosis
-
Compston D.A., Batchelor J.R., and McDonald W.I. B-lymphocyte alloantigens associated with multiple sclerosis. Lancet 2 (1976) 1261-1265
-
(1976)
Lancet
, vol.2
, pp. 1261-1265
-
-
Compston, D.A.1
Batchelor, J.R.2
McDonald, W.I.3
-
3
-
-
9144269888
-
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans
-
Oksenberg J.R., Barcellos L.F., Cree B.A., Baranzini S.E., Bugawan T.L., Khan O., et al. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet 74 (2004) 160-167
-
(2004)
Am J Hum Genet
, vol.74
, pp. 160-167
-
-
Oksenberg, J.R.1
Barcellos, L.F.2
Cree, B.A.3
Baranzini, S.E.4
Bugawan, T.L.5
Khan, O.6
-
4
-
-
79959524146
-
The International HapMap Consortium. A haplotype map of the human genome
-
The International HapMap Consortium. A haplotype map of the human genome. Nature 437 (2005) 1299-1320
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
5
-
-
20144388362
-
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms
-
Miretti M.M., Walsh E.C., Ke X., Delgado M., Griffiths M., Hunt S., et al. A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet 76 (2005) 634-646
-
(2005)
Am J Hum Genet
, vol.76
, pp. 634-646
-
-
Miretti, M.M.1
Walsh, E.C.2
Ke, X.3
Delgado, M.4
Griffiths, M.5
Hunt, S.6
-
6
-
-
33749515298
-
Functional epistasis on a common MHC haplotype associated with multiple sclerosis
-
Gregersen J.W., Kranc K.R., Ke X., Svendsen P., Madsen L.S., Thomsen A.R., et al. Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Nature 443 (2006) 574-577
-
(2006)
Nature
, vol.443
, pp. 574-577
-
-
Gregersen, J.W.1
Kranc, K.R.2
Ke, X.3
Svendsen, P.4
Madsen, L.S.5
Thomsen, A.R.6
-
7
-
-
0037371325
-
HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course
-
Barcellos L.F., Oksenberg J.R., Begovich A.B., Martin E.R., Schmidt S., Vittinghoff E., et al. HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. Am J Hum Genet 72 (2003) 710-716
-
(2003)
Am J Hum Genet
, vol.72
, pp. 710-716
-
-
Barcellos, L.F.1
Oksenberg, J.R.2
Begovich, A.B.3
Martin, E.R.4
Schmidt, S.5
Vittinghoff, E.6
-
8
-
-
33748740746
-
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis
-
Barcellos L.F., Sawcer S., Ramsay P.P., Baranzini S.E., Thomson G., Briggs F., et al. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet 15 (2006) 2813-2824
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2813-2824
-
-
Barcellos, L.F.1
Sawcer, S.2
Ramsay, P.P.3
Baranzini, S.E.4
Thomson, G.5
Briggs, F.6
-
9
-
-
38049170558
-
An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus
-
Deluca G.C., Ramagopalan S.V., Herrera B.M., Dyment D.A., Lincoln M.R., Montpetit A., et al. An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus. Proc Natl Acad Sci U S A 104 (2007) 20896-20901
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20896-20901
-
-
Deluca, G.C.1
Ramagopalan, S.V.2
Herrera, B.M.3
Dyment, D.A.4
Lincoln, M.R.5
Montpetit, A.6
-
10
-
-
0034678450
-
Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex
-
Krogsgaard M., Wucherpfennig K.W., Cannella B., Hansen B.E., Svejgaard A., Pyrdol J., et al. Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex. J Exp Med 191 (2000) 1395-1412
-
(2000)
J Exp Med
, vol.191
, pp. 1395-1412
-
-
Krogsgaard, M.1
Wucherpfennig, K.W.2
Cannella, B.3
Hansen, B.E.4
Svejgaard, A.5
Pyrdol, J.6
-
11
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
Hafler D.A., Compston A., Sawcer S., Lander E.S., Daly M.J., De Jager P.L., et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357 (2007) 851-862
-
(2007)
N Engl J Med
, vol.357
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
-
12
-
-
4544353193
-
Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice
-
Rich C., Link J.M., Zamora A., Jacobsen H., Meza-Romero R., Offner H., et al. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol 34 (2004) 1251-1261
-
(2004)
Eur J Immunol
, vol.34
, pp. 1251-1261
-
-
Rich, C.1
Link, J.M.2
Zamora, A.3
Jacobsen, H.4
Meza-Romero, R.5
Offner, H.6
-
13
-
-
0033786776
-
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand
-
Bielekova B., Goodwin B., Richert N., Cortese I., Kondo T., Afshar G., et al. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat Med 6 (2000) 1167-1175
-
(2000)
Nat Med
, vol.6
, pp. 1167-1175
-
-
Bielekova, B.1
Goodwin, B.2
Richert, N.3
Cortese, I.4
Kondo, T.5
Afshar, G.6
-
14
-
-
0032719206
-
A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor
-
Madsen L.S., Andersson E.C., Jansson L., krogsgaard M., Andersen C.B., Engberg J., et al. A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nat Genet 23 (1999) 343-347
-
(1999)
Nat Genet
, vol.23
, pp. 343-347
-
-
Madsen, L.S.1
Andersson, E.C.2
Jansson, L.3
krogsgaard, M.4
Andersen, C.B.5
Engberg, J.6
-
15
-
-
0028238201
-
Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide
-
Wucherpfennig K.W., Zhang J., Witek C., Matsui M., Modabber Y., Ota K., et al. Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide. J Immunol 152 (1994) 5581-5592
-
(1994)
J Immunol
, vol.152
, pp. 5581-5592
-
-
Wucherpfennig, K.W.1
Zhang, J.2
Witek, C.3
Matsui, M.4
Modabber, Y.5
Ota, K.6
-
16
-
-
0036793245
-
A functional and structural basis for TCR cross-reactivity in multiple sclerosis
-
Lang H.L.E., Jacobsen H., Ikemizu S., Andersson C., Harlos K., Madsen L., et al. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol 3 (2002) 940-943
-
(2002)
Nat Immunol
, vol.3
, pp. 940-943
-
-
Lang, H.L.E.1
Jacobsen, H.2
Ikemizu, S.3
Andersson, C.4
Harlos, K.5
Madsen, L.6
-
17
-
-
13544263584
-
High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model
-
Ellmerich S., Mycko M., Takacs K., Waldner H., Wahid F.N., Boyton R.J., et al. High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model. J Immunol 174 (2005) 1938-1946
-
(2005)
J Immunol
, vol.174
, pp. 1938-1946
-
-
Ellmerich, S.1
Mycko, M.2
Takacs, K.3
Waldner, H.4
Wahid, F.N.5
Boyton, R.J.6
-
18
-
-
4143122302
-
Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells
-
Illes Z., Stern J.N., Reddy J., Waldner H., Mycko M.P., Brosnan C.F., et al. Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells. Proc Natl Acad Sci U S A 101 (2004) 11749-11754
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 11749-11754
-
-
Illes, Z.1
Stern, J.N.2
Reddy, J.3
Waldner, H.4
Mycko, M.P.5
Brosnan, C.F.6
-
19
-
-
29744437714
-
Copolymer effects on microglia and T cells in the central nervous system of humanized mice
-
Illes Z., Stern J.N., Keskin D.B., Reddy J., Brosnan C.F., Waldner H., et al. Copolymer effects on microglia and T cells in the central nervous system of humanized mice. Eur J Immunol 35 (2005) 3683-3693
-
(2005)
Eur J Immunol
, vol.35
, pp. 3683-3693
-
-
Illes, Z.1
Stern, J.N.2
Keskin, D.B.3
Reddy, J.4
Brosnan, C.F.5
Waldner, H.6
-
20
-
-
0002440574
-
Antigen-induced death of T-lymphocytes
-
Kabelitz D., and Janssen O. Antigen-induced death of T-lymphocytes. Front Biosci 2 (1997) d61-d77
-
(1997)
Front Biosci
, vol.2
-
-
Kabelitz, D.1
Janssen, O.2
-
21
-
-
0029025441
-
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
-
Fisher G.H., Rosenberg F.J., Straus S.E., Dale J.K., Middleton L.A., Lin A.Y., et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81 (1995) 935-946
-
(1995)
Cell
, vol.81
, pp. 935-946
-
-
Fisher, G.H.1
Rosenberg, F.J.2
Straus, S.E.3
Dale, J.K.4
Middleton, L.A.5
Lin, A.Y.6
-
22
-
-
0029006893
-
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
-
Rieux-Laucat F., Le Deist F., Hivroz C., Roberts I.A., Debatin K.M., Fischer A., et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268 (1995) 1347-1349
-
(1995)
Science
, vol.268
, pp. 1347-1349
-
-
Rieux-Laucat, F.1
Le Deist, F.2
Hivroz, C.3
Roberts, I.A.4
Debatin, K.M.5
Fischer, A.6
-
23
-
-
0031827525
-
The language of gene interaction
-
Phillips P.C. The language of gene interaction. Genetics 149 (1998) 1167-1171
-
(1998)
Genetics
, vol.149
, pp. 1167-1171
-
-
Phillips, P.C.1
-
24
-
-
33745099649
-
Recognition of conserved amino acid motifs of common viruses and its role in autoimmunity
-
Sospedra M., Zhao Y., zur Hausen H., Muraro P.A., Hamashin C., de Villiers E.M., et al. Recognition of conserved amino acid motifs of common viruses and its role in autoimmunity. PLoS Pathog 1 (2005) e41
-
(2005)
PLoS Pathog
, vol.1
-
-
Sospedra, M.1
Zhao, Y.2
zur Hausen, H.3
Muraro, P.A.4
Hamashin, C.5
de Villiers, E.M.6
-
26
-
-
0026603899
-
DQ (rather than DR) gene marks susceptibility to narcolepsy
-
Matsuki K., Grumet F.C., Lin X., Gelb M., Guilleminault C., Dement W., et al. DQ (rather than DR) gene marks susceptibility to narcolepsy. Lancet 339 (1992) 1052
-
(1992)
Lancet
, vol.339
, pp. 1052
-
-
Matsuki, K.1
Grumet, F.C.2
Lin, X.3
Gelb, M.4
Guilleminault, C.5
Dement, W.6
-
27
-
-
0035091595
-
Complex HLA-DR and DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups
-
Mignot E., Lin L., Rogers W., Honda Y., Qiu X., Lin X., et al. Complex HLA-DR and DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet 68 (2001) 686-699
-
(2001)
Am J Hum Genet
, vol.68
, pp. 686-699
-
-
Mignot, E.1
Lin, L.2
Rogers, W.3
Honda, Y.4
Qiu, X.5
Lin, X.6
-
28
-
-
0027217789
-
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
-
Brown J.H., Jardetzky T.S., Gorga J.C., Stern L.J., Urban R.G., Strominger J.L., et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364 (1993) 33-39
-
(1993)
Nature
, vol.364
, pp. 33-39
-
-
Brown, J.H.1
Jardetzky, T.S.2
Gorga, J.C.3
Stern, L.J.4
Urban, R.G.5
Strominger, J.L.6
-
29
-
-
0028348369
-
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
-
Stern L.J., Brown J.H., Jardetzky T.S., Gorga J.C., Urban R.G., Strominger J.L., et al. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368 (1994) 215-221
-
(1994)
Nature
, vol.368
, pp. 215-221
-
-
Stern, L.J.1
Brown, J.H.2
Jardetzky, T.S.3
Gorga, J.C.4
Urban, R.G.5
Strominger, J.L.6
-
30
-
-
10744220502
-
Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy
-
Siebold C., Hansen B.E., Wyer J.R., Harlos K., Esnouf R.E., Svejgaard A., et al. Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. Proc Natl Acad Sci U S A 101 (2004) 1999-2004
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1999-2004
-
-
Siebold, C.1
Hansen, B.E.2
Wyer, J.R.3
Harlos, K.4
Esnouf, R.E.5
Svejgaard, A.6
-
31
-
-
0036631471
-
Selection and fine-tuning of the autoimmune T-cell repertoire
-
Anderton S.M., and Wraith D.C. Selection and fine-tuning of the autoimmune T-cell repertoire. Nat Rev Immunol 2 (2002) 487-498
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 487-498
-
-
Anderton, S.M.1
Wraith, D.C.2
-
32
-
-
0035176638
-
Negative selection during the peripheral immune response to antigen
-
Anderton S.M., Radu C.G., Lowrey P.A., Ward E.S., and Wraith D.C. Negative selection during the peripheral immune response to antigen. J Exp Med 193 (2000) 1-12
-
(2000)
J Exp Med
, vol.193
, pp. 1-12
-
-
Anderton, S.M.1
Radu, C.G.2
Lowrey, P.A.3
Ward, E.S.4
Wraith, D.C.5
-
33
-
-
0030067815
-
The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders
-
Carrasco-Marin E., Shimizu J., Kanagawa O., and Unanue E.R. The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders. J Immunol 156 (1996) 450-458
-
(1996)
J Immunol
, vol.156
, pp. 450-458
-
-
Carrasco-Marin, E.1
Shimizu, J.2
Kanagawa, O.3
Unanue, E.R.4
-
34
-
-
0036237054
-
Prospective study on the relationship between infections and multiple sclerosis exacerbations
-
Buljevac D., Flach H.Z., Hop W.C., Hijdra D., Laman J.D., Savelkoul H.F., et al. Prospective study on the relationship between infections and multiple sclerosis exacerbations. Brain 125 (2002) 952-960
-
(2002)
Brain
, vol.125
, pp. 952-960
-
-
Buljevac, D.1
Flach, H.Z.2
Hop, W.C.3
Hijdra, D.4
Laman, J.D.5
Savelkoul, H.F.6
-
35
-
-
0023651203
-
Molecular mimicry and autoimmune disease
-
Oldstone M.B.A. Molecular mimicry and autoimmune disease. Cell 50 (1987) 819-820
-
(1987)
Cell
, vol.50
, pp. 819-820
-
-
Oldstone, M.B.A.1
-
36
-
-
0034711376
-
Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins
-
Li Y., Li H., Martin R., and Mariuzza R.A. Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins. J Mol Biol 304 (2000) 177-188
-
(2000)
J Mol Biol
, vol.304
, pp. 177-188
-
-
Li, Y.1
Li, H.2
Martin, R.3
Mariuzza, R.A.4
-
37
-
-
0028823585
-
The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3
-
Ghosh P., Amaya M., Mellins E., and Wiley D.C. The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. Nature 378 (1995) 457-462
-
(1995)
Nature
, vol.378
, pp. 457-462
-
-
Ghosh, P.1
Amaya, M.2
Mellins, E.3
Wiley, D.C.4
-
38
-
-
0028068083
-
Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides
-
Vogt A.B., Kropshofer H., Kalbacher H., Kalbus M., Rammensee H.G., Coligan J.E., et al. Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides. J Immunol 153 (1994) 1665-1673
-
(1994)
J Immunol
, vol.153
, pp. 1665-1673
-
-
Vogt, A.B.1
Kropshofer, H.2
Kalbacher, H.3
Kalbus, M.4
Rammensee, H.G.5
Coligan, J.E.6
-
39
-
-
0028120895
-
Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones
-
Wucherpfennig K.W., Sette A., Southwood S., Oseroff C., Matsui M., Strominger J.L., et al. Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones. J Exp Med 179 (1994) 279-290
-
(1994)
J Exp Med
, vol.179
, pp. 279-290
-
-
Wucherpfennig, K.W.1
Sette, A.2
Southwood, S.3
Oseroff, C.4
Matsui, M.5
Strominger, J.L.6
-
40
-
-
18244392426
-
Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor
-
Hahn M., Nicholson M.J., Pyrdol J., and Wucherpfennig K.W. Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor. Nat Immunol 6 (2005) 490-496
-
(2005)
Nat Immunol
, vol.6
, pp. 490-496
-
-
Hahn, M.1
Nicholson, M.J.2
Pyrdol, J.3
Wucherpfennig, K.W.4
-
41
-
-
26644468528
-
Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule
-
Li Y., Huang Y., Lue J., Quandt J.A., Martin R., and Mariuzza R.A. Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule. EMBO J 24 (2005) 2968-2979
-
(2005)
EMBO J
, vol.24
, pp. 2968-2979
-
-
Li, Y.1
Huang, Y.2
Lue, J.3
Quandt, J.A.4
Martin, R.5
Mariuzza, R.A.6
-
42
-
-
0034329441
-
Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1
-
Hennecke J., Carfi A., and Wiley D.C. Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1. EMBO J 19 (2000) 5611-5624
-
(2000)
EMBO J
, vol.19
, pp. 5611-5624
-
-
Hennecke, J.1
Carfi, A.2
Wiley, D.C.3
-
43
-
-
33646181088
-
How TCRs bind MHCs, peptides, and coreceptors
-
Rudolph M.G., Stanfield R.L., and Wilson I.A. How TCRs bind MHCs, peptides, and coreceptors. Annu Rev Immunol 24 (2006) 419-466
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 419-466
-
-
Rudolph, M.G.1
Stanfield, R.L.2
Wilson, I.A.3
-
44
-
-
12444298109
-
Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity
-
Maynard J., Petersson K., Wilson D.H., Adams E.J., Blondelle S.E., Boulanger M.J., et al. Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity. Immunity 22 (2005) 81-92
-
(2005)
Immunity
, vol.22
, pp. 81-92
-
-
Maynard, J.1
Petersson, K.2
Wilson, D.H.3
Adams, E.J.4
Blondelle, S.E.5
Boulanger, M.J.6
|