메뉴 건너뛰기




Volumn 72, Issue 3, 2003, Pages 710-716

HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; HLA DR2 ANTIGEN;

EID: 0037371325     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/367781     Document Type: Article
Times cited : (243)

References (45)
  • 1
    • 0025138302 scopus 로고
    • T cells responsive to myelin basic protein in patients with multiple sclerosis
    • Allegretta M, Nicklas JA, Sriram S, Albertini RJ (1990) T cells responsive to myelin basic protein in patients with multiple sclerosis. Science 247:718-721
    • (1990) Science , vol.247 , pp. 718-721
    • Allegretta, M.1    Nicklas, J.A.2    Sriram, S.3    Albertini, R.J.4
  • 4
    • 0023794099 scopus 로고
    • Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbations?
    • Beck J, Rondot P, Catinot L, Falcoff E, Kirchner H, Wietzerbin J (1988) Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbations? Acta Neurol Scand 78:318-323
    • (1988) Acta Neurol Scand , vol.78 , pp. 318-323
    • Beck, J.1    Rondot, P.2    Catinot, L.3    Falcoff, E.4    Kirchner, H.5    Wietzerbin, J.6
  • 5
    • 0015252399 scopus 로고
    • HL-A antigen frequencies in multiple sclerosis: Significant increase of HL-A3, HL-A10 and WS, and decrease of HL-A12
    • Bertrams J, Kuwert E (1972) HL-A antigen frequencies in multiple sclerosis: significant increase of HL-A3, HL-A10 and WS, and decrease of HL-A12. Eur Neurol 7:74-78
    • (1972) Eur Neurol , vol.7 , pp. 74-78
    • Bertrams, J.1    Kuwert, E.2
  • 9
    • 0030587583 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion
    • Garcia-Merino A, Alper CA, Usuku K, Marcus-Bagley D, Lincoln R, Awdeh Z, Yunis EJ, Eisenbarth GS, Brink SJ, Hauser SL (1996) Tumor necrosis factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion. Hum Immunol 50:11-21
    • (1996) Hum Immunol , vol.50 , pp. 11-21
    • Garcia-Merino, A.1    Alper, C.A.2    Usuku, K.3    Marcus-Bagley, D.4    Lincoln, R.5    Awdeh, Z.6    Yunis, E.J.7    Eisenbarth, G.S.8    Brink, S.J.9    Hauser, S.L.10
  • 11
    • 0023500817 scopus 로고
    • The shared epitope hypothesis: An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • Gregersen PK, Silver J, Winchester RJ (1987) The shared epitope hypothesis: an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 30:1205-1213
    • (1987) Arthritis Rheum , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 14
  • 16
    • 0021035886 scopus 로고
    • Rating neurologic impairment in MS: An expanded disability status scale
    • Kurtzke JF (1983) Rating neurologic impairment in MS: an expanded disability status scale. Neurology 33:1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 17
    • 77649173768 scopus 로고
    • Longitudinal data analysis using generalized linear models
    • Liang KY, Zeger SL (1986) Longitudinal data analysis using generalized linear models. Biometrika 73:13-22
    • (1986) Biometrika , vol.73 , pp. 13-22
    • Liang, K.Y.1    Zeger, S.L.2
  • 18
    • 0034835051 scopus 로고    scopus 로고
    • Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis
    • Ligers A, Dyment DA, Willer CJ, Sadovnick AD, Ebers G, Risch N, Hillert J and the Canadian Collaborative Study Groups (2001) Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis. Am J Hum Genet 69:900-903
    • (2001) Am J Hum Genet , vol.69 , pp. 900-903
    • Ligers, A.1    Dyment, D.A.2    Willer, C.J.3    Sadovnick, A.D.4    Ebers, G.5    Risch, N.6    Hillert, J.7
  • 19
    • 0037181635 scopus 로고    scopus 로고
    • Patients with multiple sclerosis and risk of type 1 diabetes mellitus in Sardinia, Italy: A cohort study
    • Marrosu MG, Cocco E, Lai M, Spinicci G, Pischedda MP, Contu P (2002) Patients with multiple sclerosis and risk of type 1 diabetes mellitus in Sardinia, Italy: a cohort study. Lancet 359:1461-1465
    • (2002) Lancet , vol.359 , pp. 1461-1465
    • Marrosu, M.G.1    Cocco, E.2    Lai, M.3    Spinicci, G.4    Pischedda, M.P.5    Contu, P.6
  • 20
    • 0035076031 scopus 로고    scopus 로고
    • Correcting for a potential bias in the pedigree disequilibrium test
    • Martin ER, Bass MP, Kaplan NL (2001) Correcting for a potential bias in the pedigree disequilibrium test. Am J Hum Genet 68:1065-1067
    • (2001) Am J Hum Genet , vol.68 , pp. 1065-1067
    • Martin, E.R.1    Bass, M.P.2    Kaplan, N.L.3
  • 21
    • 0033910787 scopus 로고    scopus 로고
    • A test for linkage and association in general pedigrees: The pedigree disequilibrium test
    • Martin ER, Monks SA, Warren LL, Kaplan NL (2000) A test for linkage and association in general pedigrees: the pedigree disequilibrium test. Am J Hum Genet 67:146-154
    • (2000) Am J Hum Genet , vol.67 , pp. 146-154
    • Martin, E.R.1    Monks, S.A.2    Warren, L.L.3    Kaplan, N.L.4
  • 22
    • 0024997357 scopus 로고
    • Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals
    • Martin R, Jaraquemada D, Flerlage M, Richert J, Whitaker J, Long EO, McFarlin DE, McFarland HF (1990) Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals. J Immunol 145:540-548
    • (1990) J Immunol , vol.145 , pp. 540-548
    • Martin, R.1    Jaraquemada, D.2    Flerlage, M.3    Richert, J.4    Whitaker, J.5    Long, E.O.6    McFarlin, D.E.7    McFarland, H.F.8
  • 23
    • 25744455620 scopus 로고    scopus 로고
    • Meta analysis of relative penetrance rank order statistics with application to HLA DR-DQ genes and type 1 diabetes
    • McWeeney S, Thomson G (2000) Meta analysis of relative penetrance rank order statistics with application to HLA DR-DQ genes and type 1 diabetes. A J Hum Genet 67:A214
    • (2000) A J Hum Genet , vol.67 A214
    • McWeeney, S.1    Thomson, G.2
  • 24
    • 0031748194 scopus 로고    scopus 로고
    • Clinical demographics of multiplex families with multiple sclerosis
    • MSG Group (1998) Clinical demographics of multiplex families with multiple sclerosis. Annals of Neurology 43:530-534
    • (1998) Annals of Neurology , vol.43 , pp. 530-534
  • 26
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilities in linkage analysis
    • O'Connell JR, Weeks DE (1998) PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63:259-266
    • (1998) Am J Hum Genet , vol.63 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 28
    • 0025370870 scopus 로고
    • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
    • Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA (1990) T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 346:183-187
    • (1990) Nature , vol.346 , pp. 183-187
    • Ota, K.1    Matsui, M.2    Milford, E.L.3    Mackin, G.A.4    Weiner, H.L.5    Hafler, D.A.6
  • 29
    • 0025313253 scopus 로고
    • Lymphotoxin and tumor necrosis factor-α production by myelin basic protein-specific T cell clones correlates with encephalitogenicity
    • Powell MB, Mitchell D, Lederman J, Buckmeier J, Zamvil SS, Graham M, Ruddle NH, Steinman L (1990) Lymphotoxin and tumor necrosis factor-α production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. Int Immunol 2:539-544
    • (1990) Int Immunol , vol.2 , pp. 539-544
    • Powell, M.B.1    Mitchell, D.2    Lederman, J.3    Buckmeier, J.4    Zamvil, S.S.5    Graham, M.6    Ruddle, N.H.7    Steinman, L.8
  • 30
    • 0034991913 scopus 로고    scopus 로고
    • Additive effect of the HLA-DR15 haplotype on susceptibility to multiple sclerosis
    • Rasmussen HB, Kelly MA, Clausen J (2001) Additive effect of the HLA-DR15 haplotype on susceptibility to multiple sclerosis. Mult Scler 7:91-93
    • (2001) Mult Scler , vol.7 , pp. 91-93
    • Rasmussen, H.B.1    Kelly, M.A.2    Clausen, J.3
  • 32
    • 0031892792 scopus 로고    scopus 로고
    • Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation
    • Scholz C, Patton KT, Anderson DE, Freeman GJ, Hafler DA (1998) Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation. J Immunol 160:1532-1538
    • (1998) J Immunol , vol.160 , pp. 1532-1538
    • Scholz, C.1    Patton, K.T.2    Anderson, D.E.3    Freeman, G.J.4    Hafler, D.A.5
  • 33
    • 0032547858 scopus 로고    scopus 로고
    • Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein
    • Smith KJ, Pyrdol J, Gauthier L, Wiley DC, Wucherpfennig KW (1998) Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein. J Exp Med 188:1511-1520
    • (1998) J Exp Med , vol.188 , pp. 1511-1520
    • Smith, K.J.1    Pyrdol, J.2    Gauthier, L.3    Wiley, D.C.4    Wucherpfennig, K.W.5
  • 35
    • 0035086802 scopus 로고    scopus 로고
    • Reactivity pattern and cytokine profile of T cells primed by myelin peptides in multiple sclerosis and healthy individuals
    • Tejada-Simon MV, Hong J, Rivera VM, Zhang JZ (2001) Reactivity pattern and cytokine profile of T cells primed by myelin peptides in multiple sclerosis and healthy individuals. Eur J Immunol 31:907-917
    • (2001) Eur J Immunol , vol.31 , pp. 907-917
    • Tejada-Simon, M.V.1    Hong, J.2    Rivera, V.M.3    Zhang, J.Z.4
  • 36
    • 0029064537 scopus 로고
    • Mapping disease genes: Family-based association studies
    • Thomson G (1995) Mapping disease genes: family-based association studies. Am J Hum Genet 57:487-498
    • (1995) Am J Hum Genet , vol.57 , pp. 487-498
    • Thomson, G.1
  • 37
    • 0023252262 scopus 로고
    • HLA-DQ β gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
    • Todd JA, Bell JI, McDevitt HO (1987) HLA-DQ β gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329:599-604
    • (1987) Nature , vol.329 , pp. 599-604
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 38
    • 0027389119 scopus 로고
    • Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients
    • Valli A, Sette A, Kappos L, Oseroff C, Sidney J, Miescher G, Hochberger M, Albert ED, Adorini L (1993) Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients. J Clin Invest 91:616-628
    • (1993) J Clin Invest , vol.91 , pp. 616-628
    • Valli, A.1    Sette, A.2    Kappos, L.3    Oseroff, C.4    Sidney, J.5    Miescher, G.6    Hochberger, M.7    Albert, E.D.8    Adorini, L.9
  • 41
    • 0026654604 scopus 로고
    • Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritis
    • Weyand CM, Xie C, Goronzy JJ (1992) Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritis. J Clin Invest 89:2033-2039
    • (1992) J Clin Invest , vol.89 , pp. 2033-2039
    • Weyand, C.M.1    Xie, C.2    Goronzy, J.J.3
  • 42
    • 0029589932 scopus 로고
    • Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: Charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris
    • Wucherpfennig KW, Yu B, Bhol K, Monos DS, Argyris E, Karr RW, Ahmed AR, Strominger JL (1995) Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris. Proc Natl Acad Sci USA 92:11935-11939
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11935-11939
    • Wucherpfennig, K.W.1    Yu, B.2    Bhol, K.3    Monos, D.S.4    Argyris, E.5    Karr, R.W.6    Ahmed, A.R.7    Strominger, J.L.8
  • 43
    • 0033782915 scopus 로고    scopus 로고
    • HLA association with autoimmune disease: A failure to protect?
    • Zanelli E, Breedveld FC, de Vries RR (2000) HLA association with autoimmune disease: a failure to protect? Rheumatology 39:1060-1066
    • (2000) Rheumatology , vol.39 , pp. 1060-1066
    • Zanelli, E.1    Breedveld, F.C.2    De Vries, R.R.3
  • 44
    • 0027053029 scopus 로고
    • An overview of methods for the analysis of longitudinal data
    • Zeger SL, Liang KY (1992) An overview of methods for the analysis of longitudinal data. Stat Med 11:1825-1839
    • (1992) Stat Med , vol.11 , pp. 1825-1839
    • Zeger, S.L.1    Liang, K.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.