-
3
-
-
29944432134
-
Transcriptional regulation of PXR: identification of a PPRE within the proximal promoter responsible for fibrate-mediated transcriptional activation of PXR
-
Aouabdi S., Gibson G.G., and Plant N. Transcriptional regulation of PXR: identification of a PPRE within the proximal promoter responsible for fibrate-mediated transcriptional activation of PXR. Drug Metabolism and Disposition 34 (2006) 138-144
-
(2006)
Drug Metabolism and Disposition
, vol.34
, pp. 138-144
-
-
Aouabdi, S.1
Gibson, G.G.2
Plant, N.3
-
4
-
-
0000973407
-
Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP
-
Ashby J., and Tennant R.W. Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutation Research 257 (1991) 229-306
-
(1991)
Mutation Research
, vol.257
, pp. 229-306
-
-
Ashby, J.1
Tennant, R.W.2
-
5
-
-
2942606042
-
Carcinogenicity categorization of chemicals-new aspects to be considered in a European perspective
-
Bolt H.M., Foth H., Hengstler J.G., and Degen G.H. Carcinogenicity categorization of chemicals-new aspects to be considered in a European perspective. Toxicology Letters 151 (2004) 29-41
-
(2004)
Toxicology Letters
, vol.151
, pp. 29-41
-
-
Bolt, H.M.1
Foth, H.2
Hengstler, J.G.3
Degen, G.H.4
-
7
-
-
0035184941
-
Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis
-
Cherkaoui-Malki M., Meyer K., Cao W.Q., Latruffe N., Yeldandi A.V., Rao M.S., Bradfield C.A., and Reddy J.K. Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis. Gene Expression 9 (2001) 291-304
-
(2001)
Gene Expression
, vol.9
, pp. 291-304
-
-
Cherkaoui-Malki, M.1
Meyer, K.2
Cao, W.Q.3
Latruffe, N.4
Yeldandi, A.V.5
Rao, M.S.6
Bradfield, C.A.7
Reddy, J.K.8
-
9
-
-
0034680776
-
Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents
-
Christmann M., and Kaina B. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents. Journal of Biological Chemistry 275 (2000) 36256-36262
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 36256-36262
-
-
Christmann, M.1
Kaina, B.2
-
10
-
-
0036021212
-
Profiling of acyl-CoA oxidase-deficient and peroxisome proliferator Wy14,643-treated mouse liver protein by surface-enhanced laser desorption/ionization ProteinChip biology system
-
Chu R., Zhang W., Lim H., Yeldandi A.V., Herring C., Brumfield L., Reddy J.K., and Davison M. Profiling of acyl-CoA oxidase-deficient and peroxisome proliferator Wy14,643-treated mouse liver protein by surface-enhanced laser desorption/ionization ProteinChip biology system. Gene Expression 10 (2002) 165-177
-
(2002)
Gene Expression
, vol.10
, pp. 165-177
-
-
Chu, R.1
Zhang, W.2
Lim, H.3
Yeldandi, A.V.4
Herring, C.5
Brumfield, L.6
Reddy, J.K.7
Davison, M.8
-
11
-
-
85047684773
-
Use of proteomics for the discovery of early markers of drug toxicity
-
Collins B.C., Clarke A., Kitteringham N.R., Gallagher W.M., and Pennington S.R. Use of proteomics for the discovery of early markers of drug toxicity. Expert Opinion in Drug Metabolism and Toxicology 3 (2007) 689-704
-
(2007)
Expert Opinion in Drug Metabolism and Toxicology
, vol.3
, pp. 689-704
-
-
Collins, B.C.1
Clarke, A.2
Kitteringham, N.R.3
Gallagher, W.M.4
Pennington, S.R.5
-
12
-
-
0345549394
-
Gene expression changes in rat liver following exposure to liver growth agents: role of Kupffer cells in xenobiotic-mediated liver growth
-
Crunkhorn S.E., Plant K.E., Gibson G.G., Kramer K., Lyon J., Lord P.G., and Plant N.J. Gene expression changes in rat liver following exposure to liver growth agents: role of Kupffer cells in xenobiotic-mediated liver growth. Biochemical Pharmacology 67 (2004) 107-118
-
(2004)
Biochemical Pharmacology
, vol.67
, pp. 107-118
-
-
Crunkhorn, S.E.1
Plant, K.E.2
Gibson, G.G.3
Kramer, K.4
Lyon, J.5
Lord, P.G.6
Plant, N.J.7
-
13
-
-
33746038130
-
Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer
-
Dahl E., Kristiansen G., Gottlob K., Klaman I., Ebner E., Hinzmann B., Hermann K., Pilarsky C., Durst M., Klinkhammer-Schalke M., Blaszyk H., Knuechel R., Hartmann A., Rosenthal A., and Wild P.J. Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer. Clinical Cancer Research 12 (2006) 3950-3960
-
(2006)
Clinical Cancer Research
, vol.12
, pp. 3950-3960
-
-
Dahl, E.1
Kristiansen, G.2
Gottlob, K.3
Klaman, I.4
Ebner, E.5
Hinzmann, B.6
Hermann, K.7
Pilarsky, C.8
Durst, M.9
Klinkhammer-Schalke, M.10
Blaszyk, H.11
Knuechel, R.12
Hartmann, A.13
Rosenthal, A.14
Wild, P.J.15
-
14
-
-
20944447768
-
Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation
-
Delaney J., Hodson M.P., Thakkar H., Connor S.C., Sweatman B.C., Kenny S.P., McGill P.J., Holder J.C., Hutton K.A., Haselden J.N., and Waterfield C.J. Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation. Archives of Toxicology 79 (2005) 208-223
-
(2005)
Archives of Toxicology
, vol.79
, pp. 208-223
-
-
Delaney, J.1
Hodson, M.P.2
Thakkar, H.3
Connor, S.C.4
Sweatman, B.C.5
Kenny, S.P.6
McGill, P.J.7
Holder, J.C.8
Hutton, K.A.9
Haselden, J.N.10
Waterfield, C.J.11
-
17
-
-
34548436087
-
Genotoxicity of non-covalent interactions: DNA intercalators
-
Ferguson L.R., and Denny W.A. Genotoxicity of non-covalent interactions: DNA intercalators. Mutation Research 623 (2007) 14-23
-
(2007)
Mutation Research
, vol.623
, pp. 14-23
-
-
Ferguson, L.R.1
Denny, W.A.2
-
18
-
-
34547881497
-
A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals
-
Fielden M.R., Brennan R., and Gollub J. A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals. The Journal of Toxicological Sciences 99 (2007) 90-100
-
(2007)
The Journal of Toxicological Sciences
, vol.99
, pp. 90-100
-
-
Fielden, M.R.1
Brennan, R.2
Gollub, J.3
-
19
-
-
42149107985
-
Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat
-
Fielden M.R., Nie A., McMillian M., Elangbam C.S., Trela B.A., Yang Y., Dunn II R.T., Dragan Y., Fransson-Stehen R., Bogdanffy M., Adams S.P., Foster W.R., Chen S.J., Rossi P., Kasper P., Jacobson-Kram D., Tatsuoka K.S., Wier P.J., Gollub J., Halbert D.N., Roter A., Young J.K., Sina J.F., Marlowe J., Martus H.J., Aubrecht J., Olaharski A.J., Roome N., Nioi P., Pardo I., Snyder R., Perry R., Lord P., Mattes W., and Car B.D. Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat. The Journal of Toxicological Sciences 103 (2008) 28-34
-
(2008)
The Journal of Toxicological Sciences
, vol.103
, pp. 28-34
-
-
Fielden, M.R.1
Nie, A.2
McMillian, M.3
Elangbam, C.S.4
Trela, B.A.5
Yang, Y.6
Dunn II, R.T.7
Dragan, Y.8
Fransson-Stehen, R.9
Bogdanffy, M.10
Adams, S.P.11
Foster, W.R.12
Chen, S.J.13
Rossi, P.14
Kasper, P.15
Jacobson-Kram, D.16
Tatsuoka, K.S.17
Wier, P.J.18
Gollub, J.19
Halbert, D.N.20
Roter, A.21
Young, J.K.22
Sina, J.F.23
Marlowe, J.24
Martus, H.J.25
Aubrecht, J.26
Olaharski, A.J.27
Roome, N.28
Nioi, P.29
Pardo, I.30
Snyder, R.31
Perry, R.32
Lord, P.33
Mattes, W.34
Car, B.D.35
more..
-
20
-
-
2342447986
-
Importin 7 and Importin α/Importin β are nuclear import receptors for the glucocorticoid receptor
-
(Epub)
-
Freedman N.D., and Yamamoto K.R. Importin 7 and Importin α/Importin β are nuclear import receptors for the glucocorticoid receptor. Molecular and Cellular Biology (2004) (Epub)
-
(2004)
Molecular and Cellular Biology
-
-
Freedman, N.D.1
Yamamoto, K.R.2
-
21
-
-
37349053408
-
Literature-based compound profiling: application to toxicogenomics
-
Frijters R., Verhoeven S., Alkema W., Van Schaik R.H., and Polman J. Literature-based compound profiling: application to toxicogenomics. Pharmacogenomics 8 (2007) 1521-1534
-
(2007)
Pharmacogenomics
, vol.8
, pp. 1521-1534
-
-
Frijters, R.1
Verhoeven, S.2
Alkema, W.3
Van Schaik, R.H.4
Polman, J.5
-
23
-
-
13244286533
-
Are tumor incidence rates from chronic bioassays telling us what we need to know about carcinogens?
-
Gaylor D.W. Are tumor incidence rates from chronic bioassays telling us what we need to know about carcinogens?. Regulatory Toxicology and Pharmacology 41 (2005) 128-133
-
(2005)
Regulatory Toxicology and Pharmacology
, vol.41
, pp. 128-133
-
-
Gaylor, D.W.1
-
24
-
-
33646702398
-
Transcriptional regulation of the human pregnane-X receptor
-
Gibson G.G., Phillips A., Aouabdi S., Plant K., and Plant N. Transcriptional regulation of the human pregnane-X receptor. Drug Metabolism Reviews 38 (2006) 31-49
-
(2006)
Drug Metabolism Reviews
, vol.38
, pp. 31-49
-
-
Gibson, G.G.1
Phillips, A.2
Aouabdi, S.3
Plant, K.4
Plant, N.5
-
25
-
-
0019977410
-
Study of liver enzymes: peroxisome proliferation and tumour rates in rats at the end of carcinogenicity studies with bezafibrate and clofibrate
-
Hartig F., Stegmeier K., and Hebold G. Study of liver enzymes: peroxisome proliferation and tumour rates in rats at the end of carcinogenicity studies with bezafibrate and clofibrate. Annals of the New York Academy of Science 386 (1982) 464-467
-
(1982)
Annals of the New York Academy of Science
, vol.386
, pp. 464-467
-
-
Hartig, F.1
Stegmeier, K.2
Hebold, G.3
-
26
-
-
13844323012
-
The genetic toxicology pf putative nongenotoxic carcinogens
-
Jackson M., Stack H., and Waters M. The genetic toxicology pf putative nongenotoxic carcinogens. Mutation Research 296 (1993) 241-277
-
(1993)
Mutation Research
, vol.296
, pp. 241-277
-
-
Jackson, M.1
Stack, H.2
Waters, M.3
-
27
-
-
33751356224
-
Systems biology, metabolic modelling and metabolomics in drug discovery and development
-
Kell D.B. Systems biology, metabolic modelling and metabolomics in drug discovery and development. Drug Discovery Today 11 (2006) 1085-1092
-
(2006)
Drug Discovery Today
, vol.11
, pp. 1085-1092
-
-
Kell, D.B.1
-
28
-
-
0034725636
-
Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53
-
Kim I.S., Kim D.H., Han S.M., Chin M.U., Nam H.J., Cho H.P., Choi S.Y., Song B.J., Kim E.R., Bae Y.S., and Moon Y.H. Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53. Journal of Biological Chemistry 275 (2000) 23139-23145
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 23139-23145
-
-
Kim, I.S.1
Kim, D.H.2
Han, S.M.3
Chin, M.U.4
Nam, H.J.5
Cho, H.P.6
Choi, S.Y.7
Song, B.J.8
Kim, E.R.9
Bae, Y.S.10
Moon, Y.H.11
-
29
-
-
21544473568
-
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predictivity
-
Kirkland D., Aardema M., Henderson L., and Muller L. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predictivity. Mutation Research 584 (2005) 1-256
-
(2005)
Mutation Research
, vol.584
, pp. 1-256
-
-
Kirkland, D.1
Aardema, M.2
Henderson, L.3
Muller, L.4
-
30
-
-
0029556851
-
Oxidative stress in nongenotoxic carcinogenesis
-
Klaunig J., Xu Y., Bachowski S., Ketcham C., Isenberg J., Kolaja K., Baker T., Walborg E., and Stevenson D. Oxidative stress in nongenotoxic carcinogenesis. The Journal of Toxicological Letters 82/83 (1995) 683-691
-
(1995)
The Journal of Toxicological Letters
, vol.82-83
, pp. 683-691
-
-
Klaunig, J.1
Xu, Y.2
Bachowski, S.3
Ketcham, C.4
Isenberg, J.5
Kolaja, K.6
Baker, T.7
Walborg, E.8
Stevenson, D.9
-
31
-
-
0036432856
-
Differential expression of classical nuclear transport factors during cellular proliferation and differentiation
-
Kohler M., Fiebeler A., Hartwig M., Thiel S., Prehn S., Kettritz R., Luft F.C., and Hartmann E. Differential expression of classical nuclear transport factors during cellular proliferation and differentiation. Cellular Physiology and Biochemistry 12 (2002) 335-344
-
(2002)
Cellular Physiology and Biochemistry
, vol.12
, pp. 335-344
-
-
Kohler, M.1
Fiebeler, A.2
Hartwig, M.3
Thiel, S.4
Prehn, S.5
Kettritz, R.6
Luft, F.C.7
Hartmann, E.8
-
32
-
-
0036605185
-
Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome
-
Mann M., Ong S.E., Gronborg M., Steen H., Jensen O.N., and Pandey A. Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. Trends in Biotechnology 20 (2002) 261-268
-
(2002)
Trends in Biotechnology
, vol.20
, pp. 261-268
-
-
Mann, M.1
Ong, S.E.2
Gronborg, M.3
Steen, H.4
Jensen, O.N.5
Pandey, A.6
-
33
-
-
0041344551
-
Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein
-
Melen K., Fagerlund R., Franke J., Kohler M., Kinnunen L., and Julkunen I. Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein. Journal of Biological Chemistry 278 (2003) 28193-28200
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 28193-28200
-
-
Melen, K.1
Fagerlund, R.2
Franke, J.3
Kohler, M.4
Kinnunen, L.5
Julkunen, I.6
-
34
-
-
0028178048
-
A preliminary evaluation of the performance of the Muta Mouse (lacZ) and Big Blue (lacI) transgenic mouse mutation assays
-
Morrison V., and Ashby J. A preliminary evaluation of the performance of the Muta Mouse (lacZ) and Big Blue (lacI) transgenic mouse mutation assays. Mutagenesis 9 (1994) 367-375
-
(1994)
Mutagenesis
, vol.9
, pp. 367-375
-
-
Morrison, V.1
Ashby, J.2
-
35
-
-
33845462135
-
Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity
-
Nie A.Y., McMillian M., Parker J.B., Leone A., Bryant S., Yieh L., Bittner A., Nelson J., Carmen A., Wan J., and Lord P.G. Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity. Molecular Carcinogenesis 45 (2006) 914-933
-
(2006)
Molecular Carcinogenesis
, vol.45
, pp. 914-933
-
-
Nie, A.Y.1
McMillian, M.2
Parker, J.B.3
Leone, A.4
Bryant, S.5
Yieh, L.6
Bittner, A.7
Nelson, J.8
Carmen, A.9
Wan, J.10
Lord, P.G.11
-
36
-
-
0345708258
-
Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms
-
O'Brien T.J., Ceryak S., and Patierno S.R. Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms. Mutation Research 533 (2003) 3-36
-
(2003)
Mutation Research
, vol.533
, pp. 3-36
-
-
O'Brien, T.J.1
Ceryak, S.2
Patierno, S.R.3
-
37
-
-
0142088806
-
Quantitative structure-activity relationships for predicting mutagenicity and carcinogenicity
-
Patlewicz G., Rodford R., and Walker J.D. Quantitative structure-activity relationships for predicting mutagenicity and carcinogenicity. Environmental and Toxicological Chemistry 22 (2003) 1885-1893
-
(2003)
Environmental and Toxicological Chemistry
, vol.22
, pp. 1885-1893
-
-
Patlewicz, G.1
Rodford, R.2
Walker, J.D.3
-
38
-
-
26044475136
-
Peroxisome proliferator-activated receptor-alpha and liver cancer: where do we stand?
-
Peters J.M., Cheung C., and Gonzalez F.J. Peroxisome proliferator-activated receptor-alpha and liver cancer: where do we stand?. Journal of Molecular Medicine 83 (2005) 774-785
-
(2005)
Journal of Molecular Medicine
, vol.83
, pp. 774-785
-
-
Peters, J.M.1
Cheung, C.2
Gonzalez, F.J.3
-
39
-
-
0142154020
-
Sodium valproate induces apoptosis in the rat hepatoma cell line, FaO
-
Phillips A., Bullock T., and Plant N. Sodium valproate induces apoptosis in the rat hepatoma cell line, FaO. Toxicology 192 (2003) 219-227
-
(2003)
Toxicology
, vol.192
, pp. 219-227
-
-
Phillips, A.1
Bullock, T.2
Plant, N.3
-
40
-
-
33747107779
-
Transcriptomic and phylogenetic analysis of Kpna genes: a family of nuclear import factors modulated in xenobiotic-mediated liver growth
-
Plant K.E., Everett D.M., Gordon Gibson G., Lyon J., and Plant N.J. Transcriptomic and phylogenetic analysis of Kpna genes: a family of nuclear import factors modulated in xenobiotic-mediated liver growth. Pharmacogenetics and Genomics 16 (2006) 647-658
-
(2006)
Pharmacogenetics and Genomics
, vol.16
, pp. 647-658
-
-
Plant, K.E.1
Everett, D.M.2
Gordon Gibson, G.3
Lyon, J.4
Plant, N.J.5
-
41
-
-
4344617972
-
Interaction networks: coordinating responses to xenobiotic exposure
-
Plant N. Interaction networks: coordinating responses to xenobiotic exposure. Toxicology 202 (2004) 21-32
-
(2004)
Toxicology
, vol.202
, pp. 21-32
-
-
Plant, N.1
-
42
-
-
1642377970
-
Strategies for using in vitro screens in drug metabolism
-
Plant N. Strategies for using in vitro screens in drug metabolism. Drug Discovery Today 9 (2004) 328-336
-
(2004)
Drug Discovery Today
, vol.9
, pp. 328-336
-
-
Plant, N.1
-
43
-
-
0031658358
-
The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate
-
Plant N.J., Horley N.J., Dickins M., Hasmall S.C., Elcombe C.R., and Bell D.R. The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate. Carcinogenesis 19 (1998) 1521-1527
-
(1998)
Carcinogenesis
, vol.19
, pp. 1521-1527
-
-
Plant, N.J.1
Horley, N.J.2
Dickins, M.3
Hasmall, S.C.4
Elcombe, C.R.5
Bell, D.R.6
-
44
-
-
27844466862
-
Defining mitogen-activated protein kinase pathways with mass spectrometry-based approaches
-
Powell D.W., Pierce W.M., and McLeish K.R. Defining mitogen-activated protein kinase pathways with mass spectrometry-based approaches. Mass Spectrometry Reviews 24 (2005) 847-864
-
(2005)
Mass Spectrometry Reviews
, vol.24
, pp. 847-864
-
-
Powell, D.W.1
Pierce, W.M.2
McLeish, K.R.3
-
46
-
-
37249077516
-
Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size
-
Pushparajah D.S., Umachandran M., Nazir T., Plant K.E., Plant N., Lewis D.F., and Ioannides C. Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size. Toxicology In Vitro 22 (2008) 128-145
-
(2008)
Toxicology In Vitro
, vol.22
, pp. 128-145
-
-
Pushparajah, D.S.1
Umachandran, M.2
Nazir, T.3
Plant, K.E.4
Plant, N.5
Lewis, D.F.6
Ioannides, C.7
-
47
-
-
40649116713
-
Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: studies using precision-cut tissue slices
-
Pushparajah D.S., Umachandran M., Plant K.E., Plant N., and Ioannides C. Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: studies using precision-cut tissue slices. Mutation Research 640 (2008) 153-161
-
(2008)
Mutation Research
, vol.640
, pp. 153-161
-
-
Pushparajah, D.S.1
Umachandran, M.2
Plant, K.E.3
Plant, N.4
Ioannides, C.5
-
48
-
-
33644689203
-
Gene expression dose-response of liver with a genotoxic and nongenotoxic carcinogen
-
Seidel S.D., Stott W.T., Kan H.L., Sparrow B.R., and Gollapudi B.B. Gene expression dose-response of liver with a genotoxic and nongenotoxic carcinogen. International Journal of Toxicology 25 (2006) 57-64
-
(2006)
International Journal of Toxicology
, vol.25
, pp. 57-64
-
-
Seidel, S.D.1
Stott, W.T.2
Kan, H.L.3
Sparrow, B.R.4
Gollapudi, B.B.5
-
49
-
-
0035012857
-
A review of the genotoxicity of marketed pharmaceuticals
-
Snyder R.D., and Green J.W. A review of the genotoxicity of marketed pharmaceuticals. Mutation Research 488 (2001) 151-169
-
(2001)
Mutation Research
, vol.488
, pp. 151-169
-
-
Snyder, R.D.1
Green, J.W.2
-
50
-
-
0034653417
-
Expression profiling in toxicology-potentials and limitations
-
Steiner S., and Anderson N.L. Expression profiling in toxicology-potentials and limitations. Toxicology Letters 112-113 (2000) 467-471
-
(2000)
Toxicology Letters
, vol.112-113
, pp. 467-471
-
-
Steiner, S.1
Anderson, N.L.2
-
51
-
-
33847329758
-
A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays
-
Thomas R.S., O'Connell T.M., Pluta L., Wolfinger R.D., Yang L., and Page T.J. A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. The Journal of Toxicological Sciences 96 (2007) 40-46
-
(2007)
The Journal of Toxicological Sciences
, vol.96
, pp. 40-46
-
-
Thomas, R.S.1
O'Connell, T.M.2
Pluta, L.3
Wolfinger, R.D.4
Yang, L.5
Page, T.J.6
-
52
-
-
0025818560
-
Micronucleus morphology as a means to distinguish aneugens and clastogens in the mouse bone-marrow micronucleus assay
-
Tinwell H., and Ashby J. Micronucleus morphology as a means to distinguish aneugens and clastogens in the mouse bone-marrow micronucleus assay. Mutagenesis 6 (1991) 193-198
-
(1991)
Mutagenesis
, vol.6
, pp. 193-198
-
-
Tinwell, H.1
Ashby, J.2
-
53
-
-
33947186795
-
Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis
-
Tryndyak V.P., Kovalchuk O., Muskhelishvili L., Montgomery B., Rodriguez-Juarez R., Melnyk S., Ross S.A., Beland F.A., and Pogribny I.P. Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis. Molecular Carcinogenesis 46 (2007) 187-197
-
(2007)
Molecular Carcinogenesis
, vol.46
, pp. 187-197
-
-
Tryndyak, V.P.1
Kovalchuk, O.2
Muskhelishvili, L.3
Montgomery, B.4
Rodriguez-Juarez, R.5
Melnyk, S.6
Ross, S.A.7
Beland, F.A.8
Pogribny, I.P.9
-
54
-
-
33747888143
-
Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis
-
Tryndyak V.P., Muskhelishvili L., Kovalchuk O., Rodriguez-Juarez R., Montgomery B., Churchwell M.I., Ross S.A., Beland F.A., and Pogribny I.P. Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis. Carcinogenesis 27 (2006) 1713-1720
-
(2006)
Carcinogenesis
, vol.27
, pp. 1713-1720
-
-
Tryndyak, V.P.1
Muskhelishvili, L.2
Kovalchuk, O.3
Rodriguez-Juarez, R.4
Montgomery, B.5
Churchwell, M.I.6
Ross, S.A.7
Beland, F.A.8
Pogribny, I.P.9
-
55
-
-
0032782320
-
Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses
-
Turteltaub K.W., Dingley K.H., Curtis K.D., Malfatti M.A., Turesky R.J., Garner R.C., Felton J.S., and Lang N.P. Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses. Cancer Letters 143 (1999) 149-155
-
(1999)
Cancer Letters
, vol.143
, pp. 149-155
-
-
Turteltaub, K.W.1
Dingley, K.H.2
Curtis, K.D.3
Malfatti, M.A.4
Turesky, R.J.5
Garner, R.C.6
Felton, J.S.7
Lang, N.P.8
-
56
-
-
1542361727
-
Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression
-
Ulrich R.G., Rockett J.C., Gibson G.G., and Pettit S.D. Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression. Environmental Health Perspectives 112 (2004) 423-427
-
(2004)
Environmental Health Perspectives
, vol.112
, pp. 423-427
-
-
Ulrich, R.G.1
Rockett, J.C.2
Gibson, G.G.3
Pettit, S.D.4
-
57
-
-
3242791873
-
Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling
-
van Delft J.H., van Agen E., van Breda S.G., Herwijnen M.H., Staal Y.C., and Kleinjans J.C. Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling. Carcinogenesis 25 (2004) 1265-1276
-
(2004)
Carcinogenesis
, vol.25
, pp. 1265-1276
-
-
van Delft, J.H.1
van Agen, E.2
van Breda, S.G.3
Herwijnen, M.H.4
Staal, Y.C.5
Kleinjans, J.C.6
-
58
-
-
19644365314
-
Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling
-
van Delft J.H., van Agen E., van Breda S.G., Herwijnen M.H., Staal Y.C., and Kleinjans J.C. Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling. Mutation Research 575 (2005) 17-33
-
(2005)
Mutation Research
, vol.575
, pp. 17-33
-
-
van Delft, J.H.1
van Agen, E.2
van Breda, S.G.3
Herwijnen, M.H.4
Staal, Y.C.5
Kleinjans, J.C.6
-
59
-
-
0038715737
-
Use of microarray technologies in toxicology research
-
Vrana K.E., Freeman W.M., and Aschner M. Use of microarray technologies in toxicology research. Neurotoxicology 24 (2003) 321-332
-
(2003)
Neurotoxicology
, vol.24
, pp. 321-332
-
-
Vrana, K.E.1
Freeman, W.M.2
Aschner, M.3
-
60
-
-
0035977845
-
Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity
-
Waring J.F., Ciurlionis R., Jolly R.A., Heindel M., and Ulrich R.G. Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. Toxicology Letters 120 (2001) 359-368
-
(2001)
Toxicology Letters
, vol.120
, pp. 359-368
-
-
Waring, J.F.1
Ciurlionis, R.2
Jolly, R.A.3
Heindel, M.4
Ulrich, R.G.5
-
61
-
-
28844438237
-
Nuclear import of the retinoid X receptor, the vitamin D receptor, and their mutual heterodimer
-
Yasmin R., Williams R.M., Xu M., and Noy N. Nuclear import of the retinoid X receptor, the vitamin D receptor, and their mutual heterodimer. Journal of Biological Chemistry 280 (2005) 40152-40160
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 40152-40160
-
-
Yasmin, R.1
Williams, R.M.2
Xu, M.3
Noy, N.4
-
62
-
-
0035834654
-
Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver
-
Yu S., Cao W.Q., Kashireddy P., Meyer K., Jia Y., Hughes D.E., Tan Y., Feng J., Yeldandi A.V., Rao M.S., Costa R.H., Gonzalez F.J., and Reddy J.K. Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver. Journal of Biological Chemistry 276 (2001) 42485-42491
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 42485-42491
-
-
Yu, S.1
Cao, W.Q.2
Kashireddy, P.3
Meyer, K.4
Jia, Y.5
Hughes, D.E.6
Tan, Y.7
Feng, J.8
Yeldandi, A.V.9
Rao, M.S.10
Costa, R.H.11
Gonzalez, F.J.12
Reddy, J.K.13
-
63
-
-
33748364355
-
Proteomic profiles of induced hepatotoxicity at the subcellular level
-
Zgoda V., Tikhonova O., Viglinskaya A., Serebriakova M., Lisitsa A., and Archakov A. Proteomic profiles of induced hepatotoxicity at the subcellular level. Proteomics 6 (2006) 4662-4670
-
(2006)
Proteomics
, vol.6
, pp. 4662-4670
-
-
Zgoda, V.1
Tikhonova, O.2
Viglinskaya, A.3
Serebriakova, M.4
Lisitsa, A.5
Archakov, A.6
-
64
-
-
0033178677
-
Rat pregnane X receptor: molecular cloning, tissue distribution and xenobiotic regulation
-
Zhang H., LeCulyse E., Liu L., Hu M., Matoney L., Zhu W., and Yan B. Rat pregnane X receptor: molecular cloning, tissue distribution and xenobiotic regulation. Archives of Biochemistry and Biophysics 368 (1999) 14-22
-
(1999)
Archives of Biochemistry and Biophysics
, vol.368
, pp. 14-22
-
-
Zhang, H.1
LeCulyse, E.2
Liu, L.3
Hu, M.4
Matoney, L.5
Zhu, W.6
Yan, B.7
-
65
-
-
0034769275
-
Low doses and thresholds in genotoxicity: from theories to experiments
-
Zito R. Low doses and thresholds in genotoxicity: from theories to experiments. Journal of Experimental and Clinical Cancer Research 20 (2001) 315-325
-
(2001)
Journal of Experimental and Clinical Cancer Research
, vol.20
, pp. 315-325
-
-
Zito, R.1
|