Genomic cluster and network analysis for predictive screening for hepatotoxicity

Journal of Toxicological Sciences

Volumn 31, Issue 5, 2006, Pages 419-432

  Fukushima, Tamio ^a   Kikkawa, Rie ^a   Hamada, Yoshimasa ^a   Horii, Ikuo ^a  

^a Pfizer Japan Inc   (Japan)

Author keywords

Gene expression; GeneChip microarray; Hepatotoxicity; Hierarchical cluster analysis and network analysis

Indexed keywords

AMIODARONE; CARBON TETRACHLORIDE; FATTY ACID SYNTHASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; NUCLEAR FACTOR; PARACETAMOL; POLYSORBATE 80; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TETRACYCLINE; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLUSTER ANALYSIS; COMPUTER PROGRAM; CONTROLLED STUDY; DOWN REGULATION; DRUG OVERDOSE; GENE CONTROL; GENE EXPRESSION; GENOME ANALYSIS; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; LIPID METABOLISM; LIVER; LIVER TOXICITY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; ONCOGENE MYC; OXIDATIVE STRESS; PREDICTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SCREENING; TOXICITY;

EID: 33845978765     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.31.419     Document Type: Article

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