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Volumn 202, Issue 1-2, 2004, Pages 21-32

Interaction networks: Coordinating responses to xenobiotic exposure

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A; CYTOCHROME P450 2B; CYTOCHROME P450 2C; CYTOCHROME P450 3A; CYTOCHROME P450 ISOENZYME; CYTOKINE; DRUG METABOLIZING ENZYME; EPIDERMAL GROWTH FACTOR RECEPTOR; GONADOTROPIN; LUTEINIZING HORMONE; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PREGNANE X RECEPTOR; TESTOSTERONE; XENOBIOTIC AGENT;

EID: 4344617972     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.06.028     Document Type: Article
Times cited : (18)

References (64)
  • 1
    • 0025848853 scopus 로고
    • Localization and differential induction of cytochrome P450IVA and Acyl-CoA oxidase in reply to: Rat liver
    • D.R. Bell, R.G. Bars, G.G. Gibson, and C. Elcombe Localization and differential induction of cytochrome P450IVA and Acyl-CoA oxidase in reply to: rat liver Biochem. J. 275 1991 247 252
    • (1991) Biochem. J. , vol.275 , pp. 247-252
    • Bell, D.R.1    Bars, R.G.2    Gibson3    Elcombe, C.G.G.4
  • 3
    • 0031417341 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643
    • Bojes, H.K., Germolec, D.R., Simeonova, P., Bruccoleri, A., Schoonhoven, R., Luster, M.I., Thurman, R.G., 1997. Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643. Carcinogenesis 18, 669-674.
    • (1997) Carcinogenesis , vol.18 , pp. 669-674
    • Bojes, H.K.1    Germolec, D.R.2    Simeonova, P.3    Bruccoleri, A.4    Schoonhoven, R.5    Luster, M.I.6    Thurman, R.G.7
  • 4
    • 0030070481 scopus 로고    scopus 로고
    • Peroxisome proliferators activate kupffer cells in vivo
    • H.K. Bojes, and R.G. Thurman Peroxisome proliferators activate kupffer cells in vivo Cancer Res. 56 1996 1 4
    • (1996) Cancer Res. , vol.56 , pp. 1-4
    • Bojes1    Thurman, R.G.H.K.2
  • 5
    • 0036884167 scopus 로고    scopus 로고
    • The Use and analysis of microarray data
    • Butte, A., 2002. The Use and analysis of microarray data. Nature Reviews-Drug Discovery 1, 951-960.
    • (2002) Nature Reviews-Drug Discovery , vol.1 , pp. 951-960
    • Butte, A.1
  • 7
    • 1642569547 scopus 로고    scopus 로고
    • Protein-protein interaction networks: From interactions to networks
    • Cho, S., Park, S.G., Lee do, H., Park, B.C., 2004. Protein-protein interaction networks: from interactions to networks. J. Biochem. Mol. Biol. 37, 45-52.
    • (2004) J. Biochem. Mol. Biol. , vol.37 , pp. 45-52
    • Cho, S.1    Park, S.G.2    Lee Do, H.3    Park, B.C.4
  • 9
    • 0018828995 scopus 로고
    • Increase in Leydig cell number in testes of adult rats treated chronically with an excess of human chorionic gonadotropin
    • Christensen, A.K., Peacock, K.C., 1980. Increase in Leydig cell number in testes of adult rats treated chronically with an excess of human chorionic gonadotropin. Biol. Reprod. 22, 383-391.
    • (1980) Biol. Reprod. , vol.22 , pp. 383-391
    • Christensen, A.K.1    Peacock, K.C.2
  • 10
    • 0141794309 scopus 로고    scopus 로고
    • Lansoprazole increases testosterone metabolism and clearance in male Sprague-Dawley rats: Implications for leydig cell carcinogenesis
    • Coulson, M.D., Gibson, G.G., Plant, N., Hammond, T., Graham, M., 2003. Lansoprazole increases testosterone metabolism and clearance in male Sprague-Dawley rats: implications for leydig cell carcinogenesis. Tox. Appl. Pharm. 192, 154-163.
    • (2003) Tox. Appl. Pharm. , vol.192 , pp. 154-163
    • Coulson, M.D.1    Gibson, G.G.2    Plant, N.3    Hammond, T.4    Graham, M.5
  • 11
    • 0345549394 scopus 로고    scopus 로고
    • Gene expression changes in rat liver following exposure to liver growth agents: Role of Kupffer cells in xenobiotic-mediated liver growth
    • Crunkhorn, S.E., Plant, K.E., Gibson, G.G., Kramer, K., Lyon, J., Lord, P.G., Plant, N.J., 2004. Gene expression changes in rat liver following exposure to liver growth agents: role of Kupffer cells in xenobiotic-mediated liver growth. Biochem. Pharm. 67, 107-118.
    • (2004) Biochem. Pharm. , vol.67 , pp. 107-118
    • Crunkhorn, S.E.1    Plant, K.E.2    Gibson, G.G.3    Kramer, K.4    Lyon, J.5    Lord, P.G.6    Plant, N.J.7
  • 12
    • 0025051058 scopus 로고
    • Biologically active products of stimulated macrophages (Kupffer cells)
    • Decker, K., 1990. Biologically active products of stimulated macrophages (Kupffer cells). Eur. J. Biochem. 192, 245-261.
    • (1990) Eur. J. Biochem. , vol.192 , pp. 245-261
    • Decker, K.1
  • 13
    • 0025816839 scopus 로고
    • Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: Comparison of WY-14,643 to clofibric acid, nafenopin and LY171883
    • P. Eacho, T. Lanier, and C. Brodheckner Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: comparison of WY-14,643 to clofibric acid, nafenopin and LY171883 Carcinogenesis 12 1991 1557 1561
    • (1991) Carcinogenesis , vol.12 , pp. 1557-1561
    • Eacho, P.1    Lanier2    Brodheckner, C.T.3
  • 14
    • 0000120264 scopus 로고
    • Cell size nuclear content and the development of polyploidy in the mammalian liver
    • C.J. Epstein Cell size nuclear content and the development of polyploidy in the mammalian liver Proc. Natl. Acad. Sci. U.S.A. 57 1967 327
    • (1967) Proc. Natl. Acad. Sci. U.S.A. , vol.57 , pp. 327
    • Epstein, C.J.1
  • 15
    • 1442314719 scopus 로고    scopus 로고
    • Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice
    • Erol, E., Kumar, L.S., Cline, G.W., Shulman, G.I., Kelly, D.P., Binas, B., 2004. Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice. Faseb Journal, 18, 347-349.
    • (2004) Faseb Journal , vol.18 , pp. 347-349
    • Erol, E.1    Kumar, L.S.2    Cline, G.W.3    Shulman, G.I.4    Kelly, D.P.5    Binas, B.6
  • 16
    • 0036204734 scopus 로고    scopus 로고
    • In silico approaches to mechanistic and predictive toxicology: An introduction to bioinformatics for toxicologists
    • Fielden, M.R., Matthews, J.B., Fertuck, K.C., Halgren, R.G., Zacharewski, T.R., 2002. In silico approaches to mechanistic and predictive toxicology: an introduction to bioinformatics for toxicologists. Crit. Rev. Toxicol. 32, 67-112.
    • (2002) Crit. Rev. Toxicol. , vol.32 , pp. 67-112
    • Fielden, M.R.1    Matthews, J.B.2    Fertuck, K.C.3    Halgren, R.G.4    Zacharewski, T.R.5
  • 17
    • 0026766117 scopus 로고
    • Metabolic zonation of the liver: Regulation and implications for liver function
    • R. Gebhardt Metabolic zonation of the liver: regulation and implications for liver function Pharmaceut. Therapeut. 53 1992 275 354
    • (1992) Pharmaceut. Therapeut. , vol.53 , pp. 275-354
    • Gebhardt, R.1
  • 18
    • 0035805536 scopus 로고    scopus 로고
    • Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
    • A. Geick, M. Eichelbaum, and O. Burk Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin J. Biol. Chem. 276 2001 14581 14587
    • (2001) J. Biol. Chem. , vol.276 , pp. 14581-14587
    • Geick, A.1    Eichelbaum2    Burk, O.M.3
  • 19
  • 21
    • 0036515846 scopus 로고    scopus 로고
    • Receptor-dependent transcriptional activation of cytochrome P450 3A genes: Induction mechanisms, species differences and inter-individual variation in man
    • Gibson, G., Plant, N., Swales, K., Ayrton, A., El-Sankary, W., 2002. Receptor-dependent transcriptional activation of cytochrome P450 3A genes: induction mechanisms, species differences and inter-individual variation in man. Xenobiotica 32, 165-206.
    • (2002) Xenobiotica , vol.32 , pp. 165-206
    • Gibson, G.1    Plant, N.2    Swales, K.3    Ayrton, A.4    El-Sankary, W.5
  • 23
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • I. Issemann, and S. Green Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators Nature 347 1990 645 649
    • (1990) Nature , vol.347 , pp. 645-649
    • Issemann1    Green, S.I.2
  • 24
    • 0038482452 scopus 로고    scopus 로고
    • Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development
    • Kamiya, A., Inoue, Y., Gonzalez, F.J., 2003. Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development. Hepatology 37, 1375-1384.
    • (2003) Hepatology , vol.37 , pp. 1375-1384
    • Kamiya, A.1    Inoue, Y.2    Gonzalez, F.J.3
  • 25
    • 0027983083 scopus 로고
    • Liver fatty acid-binding protein specific mediator of the miogenesis induced by two classes of carcinogenic peroxisome proliferator
    • S.H. Khan, and S. Sorof Liver fatty acid-binding protein specific mediator of the miogenesis induced by two classes of carcinogenic peroxisome proliferator Proc. Natl. Acad. Sci. U.S.A. 91 1994 848 852
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 848-852
    • Khan1    Sorof, S.S.H.2
  • 28
    • 0028997684 scopus 로고
    • Targeted disruption of the a isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the plietropic effects of peroxisome proliferators
    • S.S.T. Lee, T. Pineau, J. Drago, E.J. Lee, J.W. Owens, D.L. Kroetz, P.M. Fernandez-Salguero, H. Westphal, and F.J. Gonzalez Targeted disruption of the a isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the plietropic effects of peroxisome proliferators Mol. Cell Biol. 15 1995 3012 3022
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.T.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal8    Gonzalez, F.J.H.9
  • 29
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann, J.M., McKee, D.D., Watson, M.A., Willson, T.M., Moore, J.T., Kliewer, S.A., 1998. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J. Clin. Invest. 102, 1016-1023.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 31
    • 0036765785 scopus 로고    scopus 로고
    • Nuclear pregnane × receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
    • Maglich, J.M., Stoltz, C.M., Goodwin, B., Hawkins-Brown, D., Moore, J.T., Kliewer, S.A., 2002. Nuclear pregnane × receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol. Pharm. 62, 638-646.
    • (2002) Mol. Pharm. , vol.62 , pp. 638-646
    • Maglich, J.M.1    Stoltz, C.M.2    Goodwin, B.3    Hawkins-Brown, D.4    Moore, J.T.5    Kliewer, S.A.6
  • 33
    • 0026620561 scopus 로고
    • Thyroid gland neoplasia: Non-genotoxic mechanisms
    • McClain, R.M., 1992. Thyroid gland neoplasia: non-genotoxic mechanisms. Toxicol. Lett. 64-65, 397-408.
    • (1992) Toxicol. Lett. , vol.64-65 , pp. 397-408
    • McClain, R.M.1
  • 34
    • 2642544592 scopus 로고    scopus 로고
    • Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
    • R. Metivier, G. Penot, M.R. Hubner, G. Reid, H. Brand, M. Kos, and F. Gannon Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter Cell 115 2003 751 763
    • (2003) Cell , vol.115 , pp. 751-763
    • Metivier, R.1    Penot, G.2    Hubner, M.R.3    Reid, G.4    Brand, H.5    Kos6    Gannon, F.M.7
  • 35
    • 0037184804 scopus 로고    scopus 로고
    • Genomics and the prediction of xenobiotic toxicity
    • Meyer, U.A., Gut, J., 2002. Genomics and the prediction of xenobiotic toxicity. Toxicol. 181-182, 463-466.
    • (2002) Toxicol. , vol.181-182 , pp. 463-466
    • Meyer, U.A.1    Gut, J.2
  • 38
    • 0031952238 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-alpha expression in human liver
    • Palmer, C.N.A., Hsu, M.H., Griffin, K.J., Raucy, J.L., Johnson, E.F., 1998. Peroxisome proliferator activated receptor-alpha expression in human liver. Mol. Pharm. 53, 14-22.
    • (1998) Mol. Pharm. , vol.53 , pp. 14-22
    • Palmer, C.N.A.1    Hsu, M.H.2    Griffin, K.J.3    Raucy, J.L.4    Johnson, E.F.5
  • 39
    • 0033931266 scopus 로고    scopus 로고
    • Dexamethasone induces pregnane × receptor and retinoid × receptor-a expression in human hepatocytes: Synergistic increase of CYP3A4 induction by pregnane × receptor
    • Pascussi, J.-M., Drocourt, L., Fabre, J.-M., Maurel, P., Vilarem, M.-J., 2000a. Dexamethasone induces pregnane × receptor and retinoid × receptor-a expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane × receptor. Mol. Pharm. 58, 361-372.
    • (2000) Mol. Pharm. , vol.58 , pp. 361-372
    • Pascussi, J.-M.1    Drocourt, L.2    Fabre, J.-M.3    Maurel, P.4    Vilarem, M.-J.5
  • 40
    • 0033664347 scopus 로고    scopus 로고
    • Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: Consequences on cytochrome P450 gene regulation
    • Pascussi, J.-M., Gerbal-Chaloin, S., Fabre, J.-M., Maurel, P., Vilarem, M.-J., 2000b. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: Consequences on cytochrome P450 gene regulation. Mol. Pharm. 58, 1441-1450.
    • (2000) Mol. Pharm. , vol.58 , pp. 1441-1450
    • Pascussi, J.-M.1    Gerbal-Chaloin, S.2    Fabre, J.-M.3    Maurel, P.4    Vilarem, M.-J.5
  • 41
    • 2942620237 scopus 로고    scopus 로고
    • Building predictive ADMET models for early decisions in drug discovery
    • Penzotti, J.E., Landrum, G.A., Putta, S., 2004. Building predictive ADMET models for early decisions in drug discovery. Curr. Op. Drug. Disc. Dev. 7, 49-61.
    • (2004) Curr. Op. Drug. Disc. Dev. , vol.7 , pp. 49-61
    • Penzotti, J.E.1    Landrum, G.A.2    Putta, S.3
  • 42
    • 0034052579 scopus 로고    scopus 로고
    • Peroxisome prolliferator activated receptor alpha is restricted to hepatic parencymal cells, not Kupffer cells: Implications for the mechanism of action of peroxisome proliferators in carcinogenesis
    • Peters, J.M., Rusyn, I., Rose, M.L., Gonzalez, F.J., Thurman, R.D., 2000. Peroxisome prolliferator activated receptor alpha is restricted to hepatic parencymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in carcinogenesis. Carcinogenesis 21, 823-826.
    • (2000) Carcinogenesis , vol.21 , pp. 823-826
    • Peters, J.M.1    Rusyn, I.2    Rose, M.L.3    Gonzalez, F.J.4    Thurman, R.D.5
  • 43
    • 0031815538 scopus 로고    scopus 로고
    • The peroxisome proliferators are hepatocyte mitogens in chemically-defined media: Glucocorticoid-induced PPAR alpha is linked to peroxisome proliferator mitogenesis
    • Plant, N., Horley, N., Savory, R., Elcombe, C., Gray, T., Bell, D., 1998. The peroxisome proliferators are hepatocyte mitogens in chemically-defined media: glucocorticoid-induced PPAR alpha is linked to peroxisome proliferator mitogenesis. Carcinogenesis 19, 925-931.
    • (1998) Carcinogenesis , vol.19 , pp. 925-931
    • Plant, N.1    Horley, N.2    Savory, R.3    Elcombe, C.4    Gray, T.5    Bell, D.6
  • 44
    • 0018888058 scopus 로고
    • Hypolipidemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
    • Reddy, J.K., Azarnoff, D.L., Hignite, C.E., 1980. Hypolipidemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature 283, 397-398.
    • (1980) Nature , vol.283 , pp. 397-398
    • Reddy, J.K.1    Azarnoff, D.L.2    Hignite, C.E.3
  • 45
    • 0017571584 scopus 로고
    • Malignant tumours in rats fed nafenopin, a hepatic peroxisome proliferator
    • J.K. Reddy, and M.S. Rao Malignant tumours in rats fed nafenopin, a hepatic peroxisome proliferator J. Natl. Cancer Inst. 59 1977 1645 1650
    • (1977) J. Natl. Cancer Inst. , vol.59 , pp. 1645-1650
    • Reddy1    Rao, M.S.J.K.2
  • 46
    • 0042268037 scopus 로고    scopus 로고
    • Dynamic visualization of expressed gene networks
    • Remy, I., Michnick, S.W., 2003. Dynamic visualization of expressed gene networks. J. Cell Physiol. 196, 419-429.
    • (2003) J. Cell Physiol. , vol.196 , pp. 419-429
    • Remy, I.1    Michnick, S.W.2
  • 47
    • 0029081713 scopus 로고
    • Non-genotoxic hepatocarcinogens stimulate DNA synthesis and their withdrawal induces apoptosis, but in different hepatocyte populations
    • R. Roberts, A. Soames, J. Gill, N. James, and E. Wheeldon Non-genotoxic hepatocarcinogens stimulate DNA synthesis and their withdrawal induces apoptosis, but in different hepatocyte populations Carcinogenesis 16 1995 1693
    • (1995) Carcinogenesis , vol.16 , pp. 1693
    • Roberts, R.1    Soames, A.2    Gill, J.3    James4    Wheeldon, E.N.5
  • 49
    • 1642579696 scopus 로고    scopus 로고
    • The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes
    • Song, X., Xie, M., Zhang, H., Li, Y., Sachdeva, K., Yan, B., 2004. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes. Drug Met. Disp. 32, 35-42.
    • (2004) Drug Met. Disp. , vol.32 , pp. 35-42
    • Song, X.1    Xie, M.2    Zhang, H.3    Li, Y.4    Sachdeva, K.5    Yan, B.6
  • 50
    • 0023769551 scopus 로고
    • A species comparison of acute hyperplasia induced by the peroxisome proliferator methylclofenopate: Involvement of the binucleated hepatocyte
    • Styles, J.A., Kelly, M., Pritchard, N.R., Elcombe, C.R., 1988. A species comparison of acute hyperplasia induced by the peroxisome proliferator methylclofenopate: involvement of the binucleated hepatocyte. Carcinogenesis 9, 1647-1655.
    • (1988) Carcinogenesis , vol.9 , pp. 1647-1655
    • Styles, J.A.1    Kelly, M.2    Pritchard, N.R.3    Elcombe, C.R.4
  • 51
    • 0037015030 scopus 로고    scopus 로고
    • Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha-interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator
    • Surapureddi, S., Yu, S., Bu, H., Hashimoto, T., Yeldandi, A.V., Kashireddy, P., Cherkaoui-Malki, M., Qi, C., Zhu, Y.J., Rao, M.S., Reddy, J.K., 2002. Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha-interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator. P.N.A.S. 99, 11836-11841.
    • (2002) P.N.A.S. , vol.99 , pp. 11836-11841
    • Surapureddi, S.1    Yu, S.2    Bu, H.3    Hashimoto, T.4    Yeldandi, A.V.5    Kashireddy, P.6    Cherkaoui-Malki, M.7    Qi, C.8    Zhu, Y.J.9    Rao, M.S.10    Reddy, J.K.11
  • 52
    • 0041529817 scopus 로고    scopus 로고
    • Relative receptor expression is a determinant in xenobiotic-mediated CYP3A induction in rat and human cells
    • Swales, K.E., Plant, N., Ayrton, A., Hood, S., Gibson, G., 2003. Relative receptor expression is a determinant in xenobiotic-mediated CYP3A induction in rat and human cells. Xenobiotica 33, 703-716.
    • (2003) Xenobiotica , vol.33 , pp. 703-716
    • Swales, K.E.1    Plant, N.2    Ayrton, A.3    Hood, S.4    Gibson, G.5
  • 53
    • 0035038919 scopus 로고    scopus 로고
    • The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
    • Synold, T.W., Dussault, I., Forman, B.M., 2001. The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nature Medicine 7, 584-590.
    • (2001) Nature Medicine , vol.7 , pp. 584-590
    • Synold, T.W.1    Dussault, I.2    Forman, B.M.3
  • 54
    • 0037031809 scopus 로고    scopus 로고
    • Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics
    • Takeshita, A., Taguchi, M., Koibuchi, N., Ozawa, Y., 2002. Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics. J. Biol. Chem. 277, 32453-32458.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32453-32458
    • Takeshita, A.1    Taguchi, M.2    Koibuchi, N.3    Ozawa, Y.4
  • 55
    • 0035977845 scopus 로고    scopus 로고
    • Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity
    • Waring, J.F., Ciurlionis, R., Jolly, R.A., Heindel, M., Ulrich, R.G., 2001a. Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. Toxicol. Lett. 120, 359-368.
    • (2001) Toxicol. Lett. , vol.120 , pp. 359-368
    • Waring, J.F.1    Ciurlionis, R.2    Jolly, R.A.3    Heindel, M.4    Ulrich, R.G.5
  • 58
    • 0023837746 scopus 로고
    • Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression
    • Waxman, D.J., 1988. Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression. Biochem. Pharm. 37, 71-84.
    • (1988) Biochem. Pharm. , vol.37 , pp. 71-84
    • Waxman, D.J.1
  • 59
    • 0036877355 scopus 로고    scopus 로고
    • Involvement of multidrug resistance proteins (MDR) in the modulation of glucocorticoid response
    • Webster, J.I., Carlstedt-Duke, J., 2002. Involvement of multidrug resistance proteins (MDR) in the modulation of glucocorticoid response. J. Steroid Biochem. Mol. Biol. 82, 277-288.
    • (2002) J. Steroid Biochem. Mol. Biol. , vol.82 , pp. 277-288
    • Webster, J.I.1    Carlstedt-Duke, J.2
  • 60
    • 1642545612 scopus 로고    scopus 로고
    • Cell cross-talk mediates PPARalpha null hepatocyte proliferation after peroxisome proliferator exposure
    • (Epub 2003 September 26).
    • Weglarz, T.C., Sandgren, E.P., 2004. Cell cross-talk mediates PPARalpha null hepatocyte proliferation after peroxisome proliferator exposure. Carcinogenesis 25, 107-12 (Epub 2003 September 26).
    • (2004) Carcinogenesis , vol.25 , pp. 107-112
    • Weglarz, T.C.1    Sandgren, E.P.2
  • 62
    • 0009744830 scopus 로고    scopus 로고
    • Kupffer cells and andothelial cells
    • A., Strain, A., Diehl (Eds.). Champan and Hall, London
    • Winwood, P., Arthur, M., 1998. Kupffer cells and andothelial cells. In: A., Strain, A., Diehl (Eds.). Liver Growth and Repair. Champan and Hall, London, pp. 482-501.
    • (1998) Liver Growth and Repair , pp. 482-501
    • Winwood, P.1    Arthur, M.2
  • 64
    • 1642360726 scopus 로고    scopus 로고
    • Herbal modulation of P-glycoprotein
    • Zhou, S., Lim, L.Y., Chowbay, B., 2004. Herbal modulation of P-glycoprotein. Drug Met. Rev. 36, 57-104.
    • (2004) Drug Met. Rev. , vol.36 , pp. 57-104
    • Zhou, S.1    Lim, L.Y.2    Chowbay, B.3


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