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Volumn 20, Issue 3, 2001, Pages 315-325

Low doses and thresholds in genotoxicity: From theories to experiments

Author keywords

DNA adducts; Genotoxic carcinogens; Low doses

Indexed keywords

CARCINOGEN; ENZYME; SCAVENGER; TUBULIN;

EID: 0034769275     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (19)

References (54)
  • 3
    • 0019306621 scopus 로고
    • Mitochondrial DNA is a major cellular target for a dihydrodiolepoxide derivative of benzo(a)pyrene
    • (1980) Science , vol.209 , pp. 297-299
    • Weinstein, B.1
  • 6
    • 0020514637 scopus 로고
    • 1 to the transcriptionally active regions of rat liver nuclear chromatm in vivo and in vitro
    • (1983) Carcinog. , vol.4 , pp. 889-893
    • Yu, F.L.1
  • 8
    • 0002059397 scopus 로고    scopus 로고
    • Repair of ionizing radiation induced DNA double-strand breaks at the c-myc locus in comparison with the overall genome
    • (1998) Int. J. Rad. Biol. , vol.73 , pp. 35-43
    • Sak, A.1    Stuschke, M.2
  • 13
    • 0021705932 scopus 로고
    • Nitrosoamine carcinogenesis in 5120 rodents
    • "N-nitrosocompounds: occurence, biological effects and relevance to human cancer". Lyon, France
    • (1984) IARC Sci. Publ. , vol.57 , pp. 627-665
    • Peto, R.1    Gray, R.2    Brantom, P.3
  • 14
    • 0025617201 scopus 로고
    • Tumors of the urinary bladder
    • "Pathology of Tumors in Laboratory Animals" Vol.1 Tumors of the Rat. (Turusov V., Mohr U. Eds). Lyon, France
    • (1990) IARC Sci. Publ. , vol.99 , pp. 345-397
    • Kunze, E.1    Chowianec, J.2
  • 16
    • 0026511077 scopus 로고
    • 12-O-tetradecanoylphorbol- 13-acetate induces selective desquamation of superficial cells in rat urinary bladder epithelium
    • (1992) Cell Tissue Res. , vol.268 , pp. 239-245
    • Watanabe, S.1    Sasaki, J.2
  • 18
    • 0020631593 scopus 로고
    • Wide range linear dose-response curve for DNA binding of orally administered benzo(a)pyrene in mice
    • (1983) Cancer Res. , vol.43 , pp. 2654-2658
    • Dunn, B.P.1
  • 26
    • 0027463574 scopus 로고
    • 1 and its implications to quantitative risk assessment
    • (1993) Mutat. Res. , vol.296 , pp. 181-198
    • Choay, W.N.1
  • 33
    • 0033257463 scopus 로고    scopus 로고
    • Formation and repair of DNA adducts in vinyl chloride and vinyl fluoride induced carcinogenesis
    • "Exocyclic DNA adducts in mutagenesis and carcinogenesis" B. Singer, H Bartsch eds., Lyon (France)
    • (1999) Iarc Sci. Publ. , vol.150 , pp. 29-43
    • Swenberg, J.A.1    Bogdanffy, M.S.2    Ham, A.3
  • 35
    • 0031408862 scopus 로고    scopus 로고
    • Near linearity adducts/tumor response was shown for lung adenomas in mice by four different carcinogenic polycyclic aromatic hydrocarbons
    • (1997) Carcinog. , vol.18 , pp. 1955-1963
    • Prahalad, A.K.1    Ross, J.A.2    Nelson, G.B.3
  • 38
    • 0024587563 scopus 로고
    • 1 carcinogen dose, indole-3-carbinol anticarcinogen dose, target organ DNA adduction and final tumor response
    • (1989) Carcinog. , vol.10 , pp. 175-181
    • Dashwood, R.H.1
  • 41
    • 0000247342 scopus 로고    scopus 로고
    • Microbeam mediated cellular effects: Single α-particle induced chromosomal damage, cell cycle delay, mutation and oncogenic transformation
    • (Goodhead D.T., O'Neill P., Menzel H.G. Eds). Special Publication, Royal Society of Chemistry, Cambridge, UK
    • (1997) Microdosimetry , vol.204 , pp. 327-330
    • Geard, C.R.1    Randers Pehrson, G.2    Hei, T.K.3
  • 43
    • 0023203726 scopus 로고
    • Lack of DNA damage or lipid peroxidation measured in vivo in the rat liver following treatment with peroxisomal proliferators
    • (1987) Carcinog. , vol.8 , pp. 1213-1218
    • Elliott, B.M.1    Elcombe, C.R.2
  • 46
  • 49
    • 2642536354 scopus 로고    scopus 로고
    • Dose-response and threshold-mediated mechanisms in mutagenesis
    • Proceedings of an International Symposium, Salzburg, Austria 7/9/98
    • (2000) Mutat. Res. , vol.464 , Issue.SPEC. ISSUE NO 1
    • Parry, J.M.1    Sarrif, A.M.2
  • 51
    • 0033985869 scopus 로고    scopus 로고
    • Threshold-mediated mechanisms in mutagenesis: Implications in the classification and regulation of chemical mutagens
    • (2000) Mutat. Res. , vol.464 , pp. 129-135
    • Crebelli, R.1
  • 53
    • 0033985347 scopus 로고    scopus 로고
    • US Environmental Protection Agency's revised guidelines for carcinogen risk assessment: Evaluating a postulated mode of carcinogenic action in guiding dose-response extrapolation
    • (2000) Mutat. Res. , vol.464 , pp. 105-115
    • Wiltse, J.A.1    Dellarco, V.L.2
  • 54
    • 0021858865 scopus 로고
    • Lack of miscoding properties of 7(2-oxoethyl) guanine the major vinyl chloride-DNA adduct
    • (1985) Cancer Res. , vol.45 , pp. 2440-2444
    • Barbin, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.