BIOASSAY;
CARCINOGENICITY;
CYTOGENETICS;
DRUG MARKETING;
DRUG STRUCTURE;
GENETIC TOXICOLOGY;
GENOTOXICITY;
LITERATURE;
LYMPHOMA;
MUTAGENESIS;
NONHUMAN;
PRIORITY JOURNAL;
REVIEW;
SISTER CHROMATID EXCHANGE;
ANIMALS;
CARCINOGENICITY TESTS;
CARCINOGENS;
DRUG APPROVAL;
DRUG TOXICITY;
HUMANS;
MARKETING OF HEALTH SERVICES;
MICE;
MUTAGENICITY TESTS;
MUTAGENS;
REFERENCE BOOKS, MEDICAL;
Cytotoxicity and chromosome aberrations in vitro: Experience in industry and the case for an upper limit on toxicity in the aberration assay
Galloway S. Cytotoxicity and chromosome aberrations in vitro: experience in industry and the case for an upper limit on toxicity in the aberration assay. Environ. Mol. Mutagen. 35:2000;191-201.
Human biological relevance and the use of threshold-arguments in regulatory genotoxicity assessment: Experience with pharmaceuticals
Muller L., Kasper P. Human biological relevance and the use of threshold-arguments in regulatory genotoxicity assessment: experience with pharmaceuticals. Mutat. Res. 464:2000;19-34.
Perspective on the usefulness of the mouse lymphoma assay as an indicator of a genotoxic carcinogen: Ten compounds which are positive in the mouse lymphoma assay but are not genotoxic carcinogens
Caldwell J. Perspective on the usefulness of the mouse lymphoma assay as an indicator of a genotoxic carcinogen: ten compounds which are positive in the mouse lymphoma assay but are not genotoxic carcinogens. Terat. Carcinogen. Mutagen. 13:1993;185-190.
Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the US NTP
Ashby J., Tennant R.W. Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the US NTP. Mutat. Res. 257:1991;229-306.
Predicting rodent carcinogenicity from four in vitro genetic toxicity assays: An evaluation of 114 chemicals studies by the national toxicology program
Haseman J.K., Zeiger E., Shelby M.D., Margolin B.H., Tennant R.W. Predicting rodent carcinogenicity from four in vitro genetic toxicity assays: an evaluation of 114 chemicals studies by the national toxicology program. J. Am. Statist. Assoc. 85:1990;964-971.
Screening for possible human carcinogens and mutagens false positives, false negatives: Statistical implications
Lovell D.P. Screening for possible human carcinogens and mutagens false positives, false negatives: statistical implications. Mutat. Res. 213:1989;43-60.
Prediction of rodent carcinogenicity utilizing a battery of in vitro and in vivo genotoxicity tests
Kim B.S., Margolin B.H. Prediction of rodent carcinogenicity utilizing a battery of in vitro and in vivo genotoxicity tests. Environ. Mol. Mutagen. 34:1999;297-304.
Carcinogenicity results for 114 laboratory animal studies used to assess the predictivity of four in vitro genetic toxicity assays for rodent carcinogenicity
Haseman J.L., Clark A.M. Carcinogenicity results for 114 laboratory animal studies used to assess the predictivity of four in vitro genetic toxicity assays for rodent carcinogenicity. Environ. Mol. Mutagen. 16(Suppl. 18):1990;15-31.