Targeting ribosomal S-6 kinase for the prevention and treatment of liver injury and liver fibrosis

Drug News and Perspectives

Volumn 21, Issue 6, 2008, Pages 301-306

  Buck, Martina ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Department of Medicine ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CCAAT ENHANCER BINDING PROTEIN BETA; DEATH RECEPTOR; DEATH RECEPTOR COMPLEX II PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RIBOSOMAL S6 PROTEIN KINASE INHIBITOR; S6 KINASE; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; APOPTOSIS; CELL ACTIVATION; CELL CYCLE REGULATION; CELL PROLIFERATION; DRUG EFFICACY; DRUG RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FIBROGENESIS; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; HUMAN; LIVER FIBROSIS; LIVER INJURY; LIVER TOXICITY; NONHUMAN; REVIEW; SIGNAL TRANSDUCTION; STELLATE CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CASPASE 8; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEPATIC STELLATE CELLS; HEPATITIS, TOXIC; HUMANS; LIVER; LIVER CIRRHOSIS; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECEPTORS, DEATH DOMAIN; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION;

EID: 56249131483     PISSN: 02140934     EISSN: None     Source Type: Journal    
DOI: 10.1358/dnp.2008.21.6.1246796     Document Type: Review

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