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Volumn , Issue , 2008, Pages

PPARδ agonism for the treatment of obesity and associated disorders: Challenges and opportunities

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 3 CHLORO 4 [3 (7 PROPYL 3 TRIFLUOROMETHYLBENZISOXAZOL 6 YLOXY)PROPYLTHIO]PHENYLACETIC ACID; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; ADIPONECTIN; CARNITINE PALMITOYLTRANSFERASE; DIURETIC AGENT; FATTY ACID; FENOFIBRATE; FIBRIC ACID DERIVATIVE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; KETONE BODY; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; N OLEOYLETHANOLAMINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PIRINIXIC ACID; PLACEBO; RETINOID X RECEPTOR; ROSIGLITAZONE; SIBUTRAMINE; TETRAHYDROLIPSTATIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 55949136076     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2008/125387     Document Type: Review
Times cited : (7)

References (104)
  • 1
    • 33846422032 scopus 로고    scopus 로고
    • Obesity and diabetes in the developing world-a growing challenge
    • Hossain P., Kawar B., El Nahas M., Obesity and diabetes in the developing world-a growing challenge The New England Journal of Medicine 2007 356 3 213 215
    • (2007) The New England Journal of Medicine , vol.356 , Issue.3 , pp. 213-215
    • Hossain, P.1    Kawar, B.2    El Nahas, M.3
  • 3
    • 0022379345 scopus 로고
    • Overweight and cancer
    • Garfinkel L., Overweight and cancer Annals of Internal Medicine 1985 103 6, part 2 1034 1036
    • (1985) Annals of Internal Medicine , vol.103 , Issue.6 PART 2 , pp. 1034-1036
    • Garfinkel, L.1
  • 4
    • 0023113933 scopus 로고
    • The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes and cardiovascular risk factors in men and women aged 18-79 years
    • Gillum R. F., The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes and cardiovascular risk factors in men and women aged 18-79 years Journal of Chronic Diseases 1987 40 5 421 428
    • (1987) Journal of Chronic Diseases , vol.40 , Issue.5 , pp. 421-428
    • Gillum, R.F.1
  • 6
    • 42149092160 scopus 로고    scopus 로고
    • Overweight and obesity are associated with psychiatric disorders: Results from the national epidemiologic survey on alcohol and related conditions
    • Petry N. M., Barry D., Pietrzak R. H., Wagner J. A., Overweight and obesity are associated with psychiatric disorders: results from the national epidemiologic survey on alcohol and related conditions Psychosomatic Medicine 2008 70 3 288 297
    • (2008) Psychosomatic Medicine , vol.70 , Issue.3 , pp. 288-297
    • Petry, N.M.1    Barry, D.2    Pietrzak, R.H.3    Wagner, J.A.4
  • 7
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • Fontana L., Eagon J. C., Trujillo M. E., Scherer P. E., Klein S., Visceral fat adipokine secretion is associated with systemic inflammation in obese humans Diabetes 2007 56 4 1010 1013
    • (2007) Diabetes , vol.56 , Issue.4 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3    Scherer, P.E.4    Klein, S.5
  • 8
    • 0038577223 scopus 로고    scopus 로고
    • Minireview: Adiposity, inflammation, and atherogenesis
    • Lyon C. J., Law R. E., Hsueh W. A., Minireview: adiposity, inflammation, and atherogenesis Endocrinology 2003 144 6 2195 2200
    • (2003) Endocrinology , vol.144 , Issue.6 , pp. 2195-2200
    • Lyon, C.J.1    Law, R.E.2    Hsueh, W.A.3
  • 9
    • 0036179818 scopus 로고    scopus 로고
    • A pilot study of long-term effects of a novel obesity treatment: Omentectomy in connection with adjustable gastric banding
    • Thörne A., Lönnqvist F., Apelman J., Hellers G., Arner P., A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding International Journal of Obesity 2002 26 2 193 199
    • (2002) International Journal of Obesity , vol.26 , Issue.2 , pp. 193-199
    • Thörne, A.1    Lönnqvist, F.2    Apelman, J.3    Hellers, G.4    Arner, P.5
  • 10
    • 2942526828 scopus 로고    scopus 로고
    • Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
    • Klein S., Fontana L., Young L., Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease The New England Journal of Medicine 2004 350 25 2549 2557
    • (2004) The New England Journal of Medicine , vol.350 , Issue.25 , pp. 2549-2557
    • Klein, S.1    Fontana, L.2    Young, L.3
  • 11
    • 37249083878 scopus 로고    scopus 로고
    • Long term pharmacotherapy for obesity and overweight: Updated meta-analysis
    • Rucker D., Padwal R., Li S. K., Curioni C., Lau D. C. W., Long term pharmacotherapy for obesity and overweight: updated meta-analysis British Medical Journal 2007 335 7631 1194 1199
    • (2007) British Medical Journal , vol.335 , Issue.7631 , pp. 1194-1199
    • Rucker, D.1    Padwal, R.2    Li, S.K.3    Curioni, C.4    Lau, D.C.W.5
  • 13
    • 33947156808 scopus 로고    scopus 로고
    • Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: An interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials
    • Buse J. B., Klonoff D. C., Nielsen L. L., Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials Clinical Therapeutics 2007 29 1 139 153
    • (2007) Clinical Therapeutics , vol.29 , Issue.1 , pp. 139-153
    • Buse, J.B.1    Klonoff, D.C.2    Nielsen, L.L.3
  • 14
    • 53749085064 scopus 로고    scopus 로고
    • Special features: Incretin-based therapies in type 2 diabetes mellitus
    • Chia C. W., Egan J. M., Special features: incretin-based therapies in type 2 diabetes mellitus The Journal of Clinical Endocrinology & Metabolism 2008 93 10 3703 3716
    • (2008) The Journal of Clinical Endocrinology & Metabolism , vol.93 , Issue.10 , pp. 3703-3716
    • Chia, C.W.1    Egan, J.M.2
  • 15
    • 38349163934 scopus 로고    scopus 로고
    • 2008, http://www.fda.gov/cder/drug/infopage/exenatide/default.htm
    • FDA, Information for Healthcare Professionals. 2008, http://www.fda.gov/ cder/drug/infopage/exenatide/default.htm
    • Information for Healthcare Professionals
    • Fda1
  • 16
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity
    • Wang Y.-X., Lee C.-H., Tiep S., Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity Cell 2003 113 2 159 170
    • (2003) Cell , vol.113 , Issue.2 , pp. 159-170
    • Wang, Y.-X.1    Lee, C.-H.2    Tiep, S.3
  • 17
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf D. J., Thummel C., Beato M., The nuclear receptor superfamily: the second decade Cell 1995 83 6 835 839
    • (1995) Cell , vol.83 , Issue.6 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 19
    • 17744413444 scopus 로고    scopus 로고
    • A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression
    • Heinzel T., Lavinsky R. M., Mullen T.-M., A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression Nature 1997 387 6628 43 48
    • (1997) Nature , vol.387 , Issue.6628 , pp. 43-48
    • Heinzel, T.1    Lavinsky, R.M.2    Mullen, T.-M.3
  • 20
    • 0029121358 scopus 로고
    • Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor
    • Cavailles V., Dauvois S., L'Horset F., Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor The EMBO Journal 1995 14 15 3741 3751
    • (1995) The EMBO Journal , vol.14 , Issue.15 , pp. 3741-3751
    • Cavailles, V.1    Dauvois, S.2    L'horset, F.3
  • 22
    • 0028846193 scopus 로고
    • Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
    • Onate S. A., Tsai S. Y., Tsai M.-J., O'Malley B. W., Sequence and characterization of a coactivator for the steroid hormone receptor superfamily Science 1995 270 5240 1354 1357
    • (1995) Science , vol.270 , Issue.5240 , pp. 1354-1357
    • Onate, S.A.1    Tsai, S.Y.2    Tsai, M.-J.3    O'Malley, B.W.4
  • 23
    • 0033583023 scopus 로고    scopus 로고
    • P300 interacts with the N- and C-terminal part of PPAR γ 2 in a ligand-independent and -dependent manner, respectively
    • Gelman L., Zhou G., Fajas L., Raspé E., Fruchart J.-C., Auwerx J., p300 interacts with the N- and C-terminal part of PPAR γ 2 in a ligand-independent and -dependent manner, respectively The Journal of Biological Chemistry 1999 274 12 7681 7688
    • (1999) The Journal of Biological Chemistry , vol.274 , Issue.12 , pp. 7681-7688
    • Gelman, L.1    Zhou, G.2    Fajas, L.3    Raspé, E.4    Fruchart, J.-C.5    Auwerx, J.6
  • 24
    • 0033523021 scopus 로고    scopus 로고
    • Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor γ
    • Heinlein C. A., Ting H.-J., Yeh S., Chang C., Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor γ The Journal of Biological Chemistry 1999 274 23 16147 16152
    • (1999) The Journal of Biological Chemistry , vol.274 , Issue.23 , pp. 16147-16152
    • Heinlein, C.A.1    Ting, H.-J.2    Yeh, S.3    Chang, C.4
  • 25
    • 33748547195 scopus 로고    scopus 로고
    • Thiazolidinediones, insulin resistance and obesity: Finding a balance
    • Wilding J., Thiazolidinediones, insulin resistance and obesity: finding a balance International Journal of Clinical Practice 2006 60 10 1272 1280
    • (2006) International Journal of Clinical Practice , vol.60 , Issue.10 , pp. 1272-1280
    • Wilding, J.1
  • 26
    • 0035430576 scopus 로고    scopus 로고
    • Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
    • de Souza C. J., Eckhardt M., Gagen K., Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance Diabetes 2001 50 8 1863 1871
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1863-1871
    • De Souza, C.J.1    Eckhardt, M.2    Gagen, K.3
  • 27
    • 0031898610 scopus 로고    scopus 로고
    • PPAR- γ: aaadipogenic regulator and thiazolidinedione receptor
    • Spiegelman B. M., PPAR- γ: adipogenic regulator and thiazolidinedione receptor Diabetes 1998 47 4 507 514
    • (1998) Diabetes , vol.47 , Issue.4 , pp. 507-514
    • Spiegelman, B.M.1
  • 28
    • 0035798713 scopus 로고    scopus 로고
    • The mechanisms by which both heterozygous peroxisome proliferator- activated receptor γ (PPAR γ) deficiency and PPAR γ agonist improve insulin resistance
    • Yamauchi T., Kamon J., Waki H., The mechanisms by which both heterozygous peroxisome proliferator-activated receptor γ (PPAR γ) deficiency and PPAR γ agonist improve insulin resistance The Journal of Biological Chemistry 2001 276 44 41245 41254
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.44 , pp. 41245-41254
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 29
    • 0032934104 scopus 로고    scopus 로고
    • Effects of a thiazolidinedione compound on body fat and fat distribution of patients with type 2 diabetes
    • Kelly I. E., Han T. S., Walsh K., Lean M. E. J., Effects of a thiazolidinedione compound on body fat and fat distribution of patients with type 2 diabetes Diabetes Care 1999 22 2 288 293
    • (1999) Diabetes Care , vol.22 , Issue.2 , pp. 288-293
    • Kelly, I.E.1    Han, T.S.2    Walsh, K.3    Lean, M.E.J.4
  • 30
    • 0036072223 scopus 로고    scopus 로고
    • Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients
    • Miyazaki Y., Mahankali A., Matsuda M., Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients The Journal of Clinical Endocrinology & Metabolism 2002 87 6 2784 2791
    • (2002) The Journal of Clinical Endocrinology & Metabolism , vol.87 , Issue.6 , pp. 2784-2791
    • Miyazaki, Y.1    Mahankali, A.2    Matsuda, M.3
  • 31
    • 34249907880 scopus 로고    scopus 로고
    • Macrophage PPAR γ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
    • Hevener A. L., Olefsky J. M., Reichart D., Macrophage PPAR γ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones Journal of Clinical Investigation 2007 117 6 1658 1669
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.6 , pp. 1658-1669
    • Hevener, A.L.1    Olefsky, J.M.2    Reichart, D.3
  • 32
    • 12944325312 scopus 로고    scopus 로고
    • Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects
    • Hammarstedt A., Sopasakis V. R., Gogg S., Jansson P.-A., Smith U., Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects Diabetologia 2005 48 1 96 104
    • (2005) Diabetologia , vol.48 , Issue.1 , pp. 96-104
    • Hammarstedt, A.1    Sopasakis, V.R.2    Gogg, S.3    Jansson, P.-A.4    Smith, U.5
  • 33
    • 0036326005 scopus 로고    scopus 로고
    • Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPAR γ agonists
    • Jiang G., Dallas-Yang Q., Li Z., Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPAR γ agonists Diabetes 2002 51 8 2412 2419
    • (2002) Diabetes , vol.51 , Issue.8 , pp. 2412-2419
    • Jiang, G.1    Dallas-Yang, Q.2    Li, Z.3
  • 34
    • 33646852805 scopus 로고    scopus 로고
    • Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways
    • Kubota N., Terauchi Y., Kubota T., Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways The Journal of Biological Chemistry 2006 281 13 8748 8755
    • (2006) The Journal of Biological Chemistry , vol.281 , Issue.13 , pp. 8748-8755
    • Kubota, N.1    Terauchi, Y.2    Kubota, T.3
  • 35
    • 36349013615 scopus 로고    scopus 로고
    • Novel peroxisome proliferator activated receptor- α agonists
    • Fruchart J.-C., Novel peroxisome proliferator activated receptor- α agonists American Journal of Cardiology 2007 100 11, supplement 1 S41 S46
    • (2007) American Journal of Cardiology , vol.100 , Issue.11 SUPPL. 1
    • Fruchart, J.-C.1
  • 36
    • 0034994989 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in atherosclerosis and inflammation-an update
    • Elangbam C. S., Tyler R. D., Lightfoot R. M., Peroxisome proliferator-activated receptors in atherosclerosis and inflammation-an update Toxicologic Pathology 2001 29 2 224 231
    • (2001) Toxicologic Pathology , vol.29 , Issue.2 , pp. 224-231
    • Elangbam, C.S.1    Tyler, R.D.2    Lightfoot, R.M.3
  • 38
    • 0041321275 scopus 로고    scopus 로고
    • Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR- α
    • Fu J., Gaetani S., Oveisi F., Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR- α Nature 2003 425 6953 90 93
    • (2003) Nature , vol.425 , Issue.6953 , pp. 90-93
    • Fu, J.1    Gaetani, S.2    Oveisi, F.3
  • 39
    • 21244464299 scopus 로고    scopus 로고
    • Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice
    • Carmona M. C., Louche K., Nibbelink M., Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice International Journal of Obesity 2005 29 7 864 871
    • (2005) International Journal of Obesity , vol.29 , Issue.7 , pp. 864-871
    • Carmona, M.C.1    Louche, K.2    Nibbelink, M.3
  • 40
    • 0035829625 scopus 로고    scopus 로고
    • An anorexic lipid mediator regulated by feeding
    • Rodríguez de Fonseca F., Navarro M., Gómez R., An anorexic lipid mediator regulated by feeding Nature 2001 414 6860 209 212
    • (2001) Nature , vol.414 , Issue.6860 , pp. 209-212
    • Rodríguez De Fonseca, F.1    Navarro, M.2    Gómez, R.3
  • 41
    • 34249686631 scopus 로고    scopus 로고
    • Endocrine regulation of the fasting response by PPAR α -mediated induction of fibroblast growth factor 21
    • Inagaki T., Dutchak P., Zhao G., Endocrine regulation of the fasting response by PPAR α -mediated induction of fibroblast growth factor 21 Cell Metabolism 2007 5 6 415 425
    • (2007) Cell Metabolism , vol.5 , Issue.6 , pp. 415-425
    • Inagaki, T.1    Dutchak, P.2    Zhao, G.3
  • 42
    • 34249711964 scopus 로고    scopus 로고
    • Hepatic fibroblast growth factor 21 is regulated by PPAR α and is a key mediator of hepatic lipid metabolism in ketotic states
    • Badman M. K., Pissios P., Kennedy A. R., Koukos G., Flier J. S., Maratos-Flier E., Hepatic fibroblast growth factor 21 is regulated by PPAR α and is a key mediator of hepatic lipid metabolism in ketotic states Cell Metabolism 2007 5 6 426 437
    • (2007) Cell Metabolism , vol.5 , Issue.6 , pp. 426-437
    • Badman, M.K.1    Pissios, P.2    Kennedy, A.R.3    Koukos, G.4    Flier, J.S.5    Maratos-Flier, E.6
  • 43
    • 33846418834 scopus 로고    scopus 로고
    • The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21
    • Kharitonenkov A., Wroblewski V. J., Koester A., The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21 Endocrinology 2007 148 2 774 781
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 774-781
    • Kharitonenkov, A.1    Wroblewski, V.J.2    Koester, A.3
  • 44
    • 0032821484 scopus 로고    scopus 로고
    • Control of food intake by fatty acid oxidation and ketogenesis
    • Scharrer E., Control of food intake by fatty acid oxidation and ketogenesis Nutrition 1999 15 9 704 714
    • (1999) Nutrition , vol.15 , Issue.9 , pp. 704-714
    • Scharrer, E.1
  • 45
    • 0030993519 scopus 로고    scopus 로고
    • ICV β -hydroxybutyrate: Effects on food intake, body composition, and body weight in rats
    • Sun M., Martin R. J., Edwards G. L., ICV β -hydroxybutyrate: effects on food intake, body composition, and body weight in rats Physiology and Behavior 1997 61 3 433 436
    • (1997) Physiology and Behavior , vol.61 , Issue.3 , pp. 433-436
    • Sun, M.1    Martin, R.J.2    Edwards, G.L.3
  • 47
    • 33644540539 scopus 로고    scopus 로고
    • Increased infarct size and lack of hyperphagic response after focal cerebral ischemia in peroxisome proliferator-activated receptor β -deficient mice
    • Arsenijevic D., De Bilbao F., Plamondon J., Increased infarct size and lack of hyperphagic response after focal cerebral ischemia in peroxisome proliferator-activated receptor β -deficient mice Journal of Cerebral Blood Flow and Metabolism 2006 26 3 433 445
    • (2006) Journal of Cerebral Blood Flow and Metabolism , vol.26 , Issue.3 , pp. 433-445
    • Arsenijevic, D.1    De Bilbao, F.2    Plamondon, J.3
  • 48
    • 9144271149 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor δ induces fatty acid β -oxidation in skeletal muscle and attenuates metabolic syndrome
    • Tanaka T., Yamamoto J., Iwasaki S., Activation of peroxisome proliferator-activated receptor δ induces fatty acid β -oxidation in skeletal muscle and attenuates metabolic syndrome Proceedings of the National Academy of Sciences of the United States of America 2003 100 26 15924 15929
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.26 , pp. 15924-15929
    • Tanaka, T.1    Yamamoto, J.2    Iwasaki, S.3
  • 49
    • 33845940226 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor- δ, a regulator of oxidative capacity, fuel switching and cholesterol transport
    • Fürnsinn C., Willson T. M., Brunmair B., Peroxisome proliferator-activated receptor- δ, a regulator of oxidative capacity, fuel switching and cholesterol transport Diabetologia 2007 50 1 8 17
    • (2007) Diabetologia , vol.50 , Issue.1 , pp. 8-17
    • Fürnsinn, C.1    Willson, T.M.2    Brunmair, B.3
  • 50
    • 33846443997 scopus 로고    scopus 로고
    • Triglyceride: High-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor δ agonist
    • Sprecher D. L., Massien C., Pearce G., Triglyceride: high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor δ agonist Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 2 359 365
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , Issue.2 , pp. 359-365
    • Sprecher, D.L.1    Massien, C.2    Pearce, G.3
  • 51
    • 33644878086 scopus 로고    scopus 로고
    • Differential expression of peroxisomal proliferator activated receptors α and δ in skeletal muscle in response to changes in diet and exercise
    • Kannisto K., Chibalin A., Glinghammar B., Zierath J. R., Hamsten A., Ehrenborg E., Differential expression of peroxisomal proliferator activated receptors α and δ in skeletal muscle in response to changes in diet and exercise International Journal of Molecular Medicine 2006 17 1 45 52
    • (2006) International Journal of Molecular Medicine , vol.17 , Issue.1 , pp. 45-52
    • Kannisto, K.1    Chibalin, A.2    Glinghammar, B.3    Zierath, J.R.4    Hamsten, A.5    Ehrenborg, E.6
  • 52
    • 0642303113 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor δ controls muscle development and oxidative capability
    • Luquet S., Lopez-Soriano J., Holst D., Peroxisome proliferator-activated receptor δ controls muscle development and oxidative capability The FASEB Journal 2003 17 15 2299 2301
    • (2003) The FASEB Journal , vol.17 , Issue.15 , pp. 2299-2301
    • Luquet, S.1    Lopez-Soriano, J.2    Holst, D.3
  • 53
    • 24644478044 scopus 로고    scopus 로고
    • Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise
    • Mahoney D. J., Parise G., Melov S., Safdar A., Tarnopolsky M. A., Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise The FASEB Journal 2005 19 11 1498 1500
    • (2005) The FASEB Journal , vol.19 , Issue.11 , pp. 1498-1500
    • Mahoney, D.J.1    Parise, G.2    Melov, S.3    Safdar, A.4    Tarnopolsky, M.A.5
  • 54
    • 7244238303 scopus 로고    scopus 로고
    • Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) α and δ and PPAR coactivator 1 α in human skeletal muscle, but not lipid regulatory genes
    • Watt M. J., Southgate R. J., Holmes A. G., Febbraio M. A., Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) α and δ and PPAR coactivator 1 α in human skeletal muscle, but not lipid regulatory genes Journal of Molecular Endocrinology 2004 33 2 533 544
    • (2004) Journal of Molecular Endocrinology , vol.33 , Issue.2 , pp. 533-544
    • Watt, M.J.1    Southgate, R.J.2    Holmes, A.G.3    Febbraio, M.A.4
  • 55
    • 8844276054 scopus 로고    scopus 로고
    • Regulation of muscle fiber type and running endurance by PPAR δ
    • Wang Y.-X., Zhang C.-L., Yu R. T., Regulation of muscle fiber type and running endurance by PPAR δ PLoS Biology 2004 2 10 e294
    • (2004) PLoS Biology , vol.2 , Issue.10 , pp. 294
    • Wang, Y.-X.1    Zhang, C.-L.2    Yu, R.T.3
  • 57
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPAR δ regulate macrophage polarization and insulin sensitivity
    • Kang K., Reilly S. M., Karabacak V., Adipocyte-derived Th2 cytokines and myeloid PPAR δ regulate macrophage polarization and insulin sensitivity Cell Metabolism 2008 7 6 485 495
    • (2008) Cell Metabolism , vol.7 , Issue.6 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3
  • 58
    • 44349161098 scopus 로고    scopus 로고
    • Alternative M2 activation of Kupffer cells by PPAR δ ameliorates obesity-induced insulin resistance
    • Odegaard J. I., Ricardo-Gonzalez R. R., Eagle A. R., Alternative M2 activation of Kupffer cells by PPAR δ ameliorates obesity-induced insulin resistance Cell Metabolism 2008 7 6 496 507
    • (2008) Cell Metabolism , vol.7 , Issue.6 , pp. 496-507
    • Odegaard, J.I.1    Ricardo-Gonzalez, R.R.2    Eagle, A.R.3
  • 59
    • 0031915653 scopus 로고    scopus 로고
    • A peroxisome proliferator-activated receptor-alpha (PPAR α) cDNA cloned from guinea-pig liver encodes a protein wit h similar properties to the mouse PPAR α: iiimplications for species differences in responses to peroxisome proliferators
    • Tugwood J. D., Holden P. R., James N. H., Prince R. A., Roberts R. A., A peroxisome proliferator-activated receptor-alpha (PPAR α) cDNA cloned from guinea-pig liver encodes a protein wit h similar properties to the mouse PPAR α: implications for species differences in responses to peroxisome proliferators Archives of Toxicology 1998 72 3 169 177
    • (1998) Archives of Toxicology , vol.72 , Issue.3 , pp. 169-177
    • Tugwood, J.D.1    Holden, P.R.2    James, N.H.3    Prince, R.A.4    Roberts, R.A.5
  • 61
    • 85047693466 scopus 로고    scopus 로고
    • Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPAR α, β / δ, and γ
    • Li A. C., Binder C. J., Gutierrez A., Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPAR α, β / δ, and γ Journal of Clinical Investigation 2004 114 11 1564 1576
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.11 , pp. 1564-1576
    • Li, A.C.1    Binder, C.J.2    Gutierrez, A.3
  • 64
    • 0032475854 scopus 로고    scopus 로고
    • The nuclear receptors peroxisome proliferator-activated receptor α and Rev-erb α mediate the species-specific regulation of apolipoprotein A-I expression by fibrates
    • Vu-Dac N., Chopin-Delannoy S., Gervois P., The nuclear receptors peroxisome proliferator-activated receptor α and Rev-erb α mediate the species-specific regulation of apolipoprotein A-I expression by fibrates The Journal of Biological Chemistry 1998 273 40 25713 25720
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.40 , pp. 25713-25720
    • Vu-Dac, N.1    Chopin-Delannoy, S.2    Gervois, P.3
  • 65
    • 0031748864 scopus 로고    scopus 로고
    • Regulation of apo A-I gene expression by fibrates
    • supplement 1
    • Staels B., Auwerx J., Regulation of apo A-I gene expression by fibrates Atherosclerosis 1998 137 supplement 1 S19 S23
    • (1998) Atherosclerosis , vol.137
    • Staels, B.1    Auwerx, J.2
  • 66
    • 33847787711 scopus 로고    scopus 로고
    • Indanylacetic acid derivatives carrying 4-thiazolyl-phenoxy tail groups, a new class of potent PPAR α / γ / δ pan agonists: Synthesis, structure-activity relationship, and in vivo efficacy
    • Rudolph J., Libing C., Majumdar D., Indanylacetic acid derivatives carrying 4-thiazolyl-phenoxy tail groups, a new class of potent PPAR α / γ / δ pan agonists: synthesis, structure-activity relationship, and in vivo efficacy Journal of Medicinal Chemistry 2007 50 5 984 1000
    • (2007) Journal of Medicinal Chemistry , vol.50 , Issue.5 , pp. 984-1000
    • Rudolph, J.1    Libing, C.2    Majumdar, D.3
  • 67
    • 0033525535 scopus 로고    scopus 로고
    • Novel peroxisome proliferator-activated receptor (PPAR) γ and PPAR δ ligands produce distinct biological effects
    • Berger J., Leibowitz M. D., Doebber T. W., Novel peroxisome proliferator-activated receptor (PPAR) γ and PPAR δ ligands produce distinct biological effects The Journal of Biological Chemistry 1999 274 10 6718 6725
    • (1999) The Journal of Biological Chemistry , vol.274 , Issue.10 , pp. 6718-6725
    • Berger, J.1    Leibowitz, M.D.2    Doebber, T.W.3
  • 68
    • 0030062325 scopus 로고    scopus 로고
    • The structure-activity relationship between peroxisome proliferator-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones
    • Willson T. M., Cobb J. E., Cowan D. J., The structure-activity relationship between peroxisome proliferator-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones Journal of Medicinal Chemistry 1996 39 3 665 668
    • (1996) Journal of Medicinal Chemistry , vol.39 , Issue.3 , pp. 665-668
    • Willson, T.M.1    Cobb, J.E.2    Cowan, D.J.3
  • 69
    • 55949088646 scopus 로고    scopus 로고
    • PPAR pan agonists: Novel approaches to treating type 2 diabetes and metabolic syndrome
    • supplement
    • Perreault M., PPAR pan agonists: novel approaches to treating type 2 diabetes and metabolic syndrome Obesity 2006 14 supplement A62
    • (2006) Obesity , vol.14 , pp. 62
    • Perreault, M.1
  • 70
    • 55949088646 scopus 로고    scopus 로고
    • PPAR pan agonists induce body weight loss in DIO mice
    • supplement
    • Perreault M., PPAR pan agonists induce body weight loss in DIO mice Obesity 2006 14 supplement A62
    • (2006) Obesity , vol.14 , pp. 62
    • Perreault, M.1
  • 71
    • 36749052873 scopus 로고    scopus 로고
    • Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity
    • Cheol S. C., Savage D. B., Abu-Elheiga L., Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity Proceedings of the National Academy of Sciences of the United States of America 2007 104 42 16480 16485
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.42 , pp. 16480-16485
    • Cheol, S.C.1    Savage, D.B.2    Abu-Elheiga, L.3
  • 72
    • 0035970805 scopus 로고    scopus 로고
    • Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-COA carboxylase 2
    • Abu-Elheiga L., Matzuk M. M., Abo-Hashema K. A. H., Wakil S. J., Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-COA carboxylase 2 Science 2001 291 5513 2613 2616
    • (2001) Science , vol.291 , Issue.5513 , pp. 2613-2616
    • Abu-Elheiga, L.1    Matzuk, M.M.2    Abo-Hashema, K.A.H.3    Wakil, S.J.4
  • 73
    • 22544462381 scopus 로고    scopus 로고
    • A potential link between muscle peroxisome proliferator-activated receptor- α signaling and obesity-related diabetes
    • Finck B. N., Bernal-Mizrachi C., Han D. H., A potential link between muscle peroxisome proliferator-activated receptor- α signaling and obesity-related diabetes Cell Metabolism 2005 1 2 133 144
    • (2005) Cell Metabolism , vol.1 , Issue.2 , pp. 133-144
    • Finck, B.N.1    Bernal-Mizrachi, C.2    Han, D.H.3
  • 74
    • 15944376229 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor δ (PPAR δ) agonist but not PPAR α corrects carnitine palmitoyl transferase 2 deficiency in human muscle cells
    • Djouadi F., Aubey F., Schlemmer D., Bastin J., Peroxisome proliferator activated receptor δ (PPAR δ) agonist but not PPAR α corrects carnitine palmitoyl transferase 2 deficiency in human muscle cells The Journal of Clinical Endocrinology & Metabolism 2005 90 3 1791 1797
    • (2005) The Journal of Clinical Endocrinology & Metabolism , vol.90 , Issue.3 , pp. 1791-1797
    • Djouadi, F.1    Aubey, F.2    Schlemmer, D.3    Bastin, J.4
  • 75
    • 33748809545 scopus 로고    scopus 로고
    • A critical role for peroxisomal proliferator-activated receptor- α nuclear receptors in the development of cardiomyocyte degeneration and necrosis
    • Pruimboom-Brees I., Haghpassand M., Royer L., A critical role for peroxisomal proliferator-activated receptor- α nuclear receptors in the development of cardiomyocyte degeneration and necrosis American Journal of Pathology 2006 169 3 750 760
    • (2006) American Journal of Pathology , vol.169 , Issue.3 , pp. 750-760
    • Pruimboom-Brees, I.1    Haghpassand, M.2    Royer, L.3
  • 76
    • 0037417725 scopus 로고    scopus 로고
    • A critical role for PPAR α -mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
    • Finck B. N., Han X., Courtois M., A critical role for PPAR α -mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content Proceedings of the National Academy of Sciences of the United States of America 2003 100 3 1226 1231
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.3 , pp. 1226-1231
    • Finck, B.N.1    Han, X.2    Courtois, M.3
  • 77
    • 36849068108 scopus 로고    scopus 로고
    • Nuclear receptors PPAR β / δ and PPAR α direct distinct metabolic regulatory programs in the mouse heart
    • Burkart E. M., Sambandam N., Han X., Nuclear receptors PPAR β / δ and PPAR α direct distinct metabolic regulatory programs in the mouse heart Journal of Clinical Investigation 2007 117 12 3930 3939
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.12 , pp. 3930-3939
    • Burkart, E.M.1    Sambandam, N.2    Han, X.3
  • 78
    • 30744460411 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor δ (PPAR δ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis
    • Pesant M., Sueur S., Dutartre P., Peroxisome proliferator-activated receptor δ (PPAR δ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis Cardiovascular Research 2006 69 2 440 449
    • (2006) Cardiovascular Research , vol.69 , Issue.2 , pp. 440-449
    • Pesant, M.1    Sueur, S.2    Dutartre, P.3
  • 79
    • 37449020075 scopus 로고    scopus 로고
    • Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
    • Koves T. R., Ussher J. R., Noland R. C., Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance Cell Metabolism 2008 7 1 45 56
    • (2008) Cell Metabolism , vol.7 , Issue.1 , pp. 45-56
    • Koves, T.R.1    Ussher, J.R.2    Noland, R.C.3
  • 81
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen S. E., Wolski K., Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes The New England Journal of Medicine 2007 356 24 2457 2471
    • (2007) The New England Journal of Medicine , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 83
    • 35848930559 scopus 로고    scopus 로고
    • Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death
    • Diamond G. A., Bax L., Kaul S., Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death Annals of Internal Medicine 2007 147 8 578 581
    • (2007) Annals of Internal Medicine , vol.147 , Issue.8 , pp. 578-581
    • Diamond, G.A.1    Bax, L.2    Kaul, S.3
  • 85
    • 34548590934 scopus 로고    scopus 로고
    • Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials
    • Lincoff A. M., Wolski K., Nicholls S. J., Nissen S. E., Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials Journal of the American Medical Association 2007 298 10 1180 1188
    • (2007) Journal of the American Medical Association , vol.298 , Issue.10 , pp. 1180-1188
    • Lincoff, A.M.1    Wolski, K.2    Nicholls, S.J.3    Nissen, S.E.4
  • 86
    • 21544466158 scopus 로고    scopus 로고
    • A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia
    • Goldberg R. B., Kendall D. M., Deeg M. A., A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia Diabetes Care 2005 28 7 1547 1554
    • (2005) Diabetes Care , vol.28 , Issue.7 , pp. 1547-1554
    • Goldberg, R.B.1    Kendall, D.M.2    Deeg, M.A.3
  • 87
    • 36048957806 scopus 로고    scopus 로고
    • Pioglitazone stimulates apolipoprotein A-I production without affecting HDL removal in HepG2 cells: Involvement of PPAR- α
    • Qin S., Liu T., Kamanna V. S., Kashyap M. L., Pioglitazone stimulates apolipoprotein A-I production without affecting HDL removal in HepG2 cells: involvement of PPAR- α Arteriosclerosis, Thrombosis, and Vascular Biology 2007 27 11 2428 2434
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , Issue.11 , pp. 2428-2434
    • Qin, S.1    Liu, T.2    Kamanna, V.S.3    Kashyap, M.L.4
  • 88
    • 0034735992 scopus 로고    scopus 로고
    • Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone
    • Sakamoto J., Kimura H., Moriyama S., Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone Biochemical and Biophysical Research Communications 2000 278 3 704 711
    • (2000) Biochemical and Biophysical Research Communications , vol.278 , Issue.3 , pp. 704-711
    • Sakamoto, J.1    Kimura, H.2    Moriyama, S.3
  • 89
  • 91
    • 34250826679 scopus 로고    scopus 로고
    • Rosiglitazone and cardiotoxicity-weighing the evidence
    • Nathan D. M., Rosiglitazone and cardiotoxicity-weighing the evidence The New England Journal of Medicine 2007 357 1 64 66
    • (2007) The New England Journal of Medicine , vol.357 , Issue.1 , pp. 64-66
    • Nathan, D.M.1
  • 92
    • 34250828630 scopus 로고    scopus 로고
    • The record on rosiglitazone and the risk of myocardial infarction
    • Psaty B. M., Furberg C. D., The record on rosiglitazone and the risk of myocardial infarction The New England Journal of Medicine 2007 357 1 67 69
    • (2007) The New England Journal of Medicine , vol.357 , Issue.1 , pp. 67-69
    • Psaty, B.M.1    Furberg, C.D.2
  • 94
    • 38349114738 scopus 로고    scopus 로고
    • Current status of carcinogenicity assessment of peroxisome proliferator-activated receptor agonists by the US FDA and a mode-of-action approach to the carcinogenic potential
    • Aoki T., Current status of carcinogenicity assessment of peroxisome proliferator-activated receptor agonists by the US FDA and a mode-of-action approach to the carcinogenic potential Journal of Toxicologic Pathology 2008 20 4 197 202
    • (2008) Journal of Toxicologic Pathology , vol.20 , Issue.4 , pp. 197-202
    • Aoki, T.1
  • 96
    • 48649095960 scopus 로고    scopus 로고
    • Rosiglitazone-associated fractures in type 2 diabetes: An analysis from a Diabetes Outcome Progression Trial (ADOPT)
    • Kahn S. E., Zinman B., Lachin J. M., Rosiglitazone-associated fractures in type 2 diabetes: an analysis from A Diabetes Outcome Progression Trial (ADOPT) Diabetes Care 2008 31 5 845 851
    • (2008) Diabetes Care , vol.31 , Issue.5 , pp. 845-851
    • Kahn, S.E.1    Zinman, B.2    Lachin, J.M.3
  • 98
    • 34250847265 scopus 로고    scopus 로고
    • Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone
    • Lazarenko O. P., Rzonca S. O., Hogue W. R., Swain F. L., Suva L. J., Lecka-Czernik B., Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone Endocrinology 2007 148 6 2669 2680
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 2669-2680
    • Lazarenko, O.P.1    Rzonca, S.O.2    Hogue, W.R.3    Swain, F.L.4    Suva, L.J.5    Lecka-Czernik, B.6
  • 99
    • 14244250617 scopus 로고    scopus 로고
    • Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation
    • Ali A. A., Weinstein R. S., Stewart S. A., Parfitt A. M., Manolagas S. C., Jilka R. L., Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation Endocrinology 2005 146 3 1226 1235
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1226-1235
    • Ali, A.A.1    Weinstein, R.S.2    Stewart, S.A.3    Parfitt, A.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 100
    • 36849034568 scopus 로고    scopus 로고
    • PPAR- γ regulates osteoclastogenesis in mice
    • Wan Y., Chong L.-W., Evans R. M., PPAR- γ regulates osteoclastogenesis in mice Nature Medicine 2007 13 12 1496 1503
    • (2007) Nature Medicine , vol.13 , Issue.12 , pp. 1496-1503
    • Wan, Y.1    Chong, L.-W.2    Evans, R.M.3
  • 102
    • 0034616069 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts
    • Jackson S. M., Demer L. L., Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts FEBS Letters 2000 471 1 119 124
    • (2000) FEBS Letters , vol.471 , Issue.1 , pp. 119-124
    • Jackson, S.M.1    Demer, L.L.2
  • 103
    • 0034678061 scopus 로고    scopus 로고
    • Cloning and function of rabbit peroxisome proliferator-activated receptor δ / β in mature osteoclasts
    • Mano H., Kimura C., Fujisawa Y., Cloning and function of rabbit peroxisome proliferator-activated receptor δ / β in mature osteoclasts The Journal of Biological Chemistry 2000 275 11 8126 8132
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.11 , pp. 8126-8132
    • Mano, H.1    Kimura, C.2    Fujisawa, Y.3
  • 104
    • 23944469952 scopus 로고    scopus 로고
    • Expression of PPAR γ and β / δ in human primary osteoblastic cells: Influence of polyunsaturated fatty acids
    • Maurin A. C., Chavassieux P. M., Meunier P. J., Expression of PPAR γ and β / δ in human primary osteoblastic cells: influence of polyunsaturated fatty acids Calcified Tissue International 2005 76 5 385 392
    • (2005) Calcified Tissue International , vol.76 , Issue.5 , pp. 385-392
    • Maurin, A.C.1    Chavassieux, P.M.2    Meunier, P.J.3


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