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Volumn 68, Issue 21, 2008, Pages 8852-8860

Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA SECRETASE INHIBITOR; NOTCH3 RECEPTOR; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR PBX1;

EID: 55349117772     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-0517     Document Type: Article
Times cited : (63)

References (44)
  • 1
    • 9244221172 scopus 로고    scopus 로고
    • Tissue repair and stem cell renewal in carcinogenesis
    • Beachy PA, Karhadkar SS, Berman DM. Tissue repair and stem cell renewal in carcinogenesis. Nature 2004;432:324-31.
    • (2004) Nature , vol.432 , pp. 324-331
    • Beachy, P.A.1    Karhadkar, S.S.2    Berman, D.M.3
  • 2
    • 5044225888 scopus 로고    scopus 로고
    • Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
    • Weng AP, Ferrando AA, Lee W, et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004;306:269-71.
    • (2004) Science , vol.306 , pp. 269-271
    • Weng, A.P.1    Ferrando, A.A.2    Lee, W.3
  • 3
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen LW, Bird J, West DC, et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991;66:649-61.
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3
  • 4
    • 0034674896 scopus 로고    scopus 로고
    • Chromosome 19 translocation, overexpression of Notch3, and human lung cancer
    • Dang TP, Gazdar AF, Virmani AK, et al. Chromosome 19 translocation, overexpression of Notch3, and human lung cancer. J Natl Cancer Inst 2000;92:1355-7.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1355-1357
    • Dang, T.P.1    Gazdar, A.F.2    Virmani, A.K.3
  • 5
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood LD, Parsons DW, Jones S, et al. The genomic landscapes of human breast and colorectal cancers. Science 2007;318:1108-13.
    • (2007) Science , vol.318 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3
  • 7
    • 20844455582 scopus 로고    scopus 로고
    • Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays
    • Matsuzaki H, Dong S, Loi H, et al. Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays. Nat Methods 2004;1:109-11.
    • (2004) Nat Methods , vol.1 , pp. 109-111
    • Matsuzaki, H.1    Dong, S.2    Loi, H.3
  • 8
    • 33745685874 scopus 로고    scopus 로고
    • Notch-3 gene amplification in ovarian cancer
    • Park JT, Li M, Nakayama N, et al. Notch-3 gene amplification in ovarian cancer. Cancer Res 2006;66:6312-8.
    • (2006) Cancer Res , vol.66 , pp. 6312-6318
    • Park, J.T.1    Li, M.2    Nakayama, N.3
  • 9
    • 33746546368 scopus 로고    scopus 로고
    • c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
    • Weng AP, Millholland JM, Yashiro-Ohtani Y, et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev 2006;20:2096-109.
    • (2006) Genes Dev , vol.20 , pp. 2096-2109
    • Weng, A.P.1    Millholland, J.M.2    Yashiro-Ohtani, Y.3
  • 10
    • 33645751939 scopus 로고    scopus 로고
    • Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis
    • Talora C, Cialfi S, Oliviero C, et al. Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis. Blood 2006;107:3313-20.
    • (2006) Blood , vol.107 , pp. 3313-3320
    • Talora, C.1    Cialfi, S.2    Oliviero, C.3
  • 12
    • 0034902568 scopus 로고    scopus 로고
    • Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic)
    • Ronchini C, Capobianco AJ. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). Mol Cell Biol 2001;21:5925-34.
    • (2001) Mol Cell Biol , vol.21 , pp. 5925-5934
    • Ronchini, C.1    Capobianco, A.J.2
  • 13
    • 0041672357 scopus 로고    scopus 로고
    • Identifying tumor origin using a gene expression-based classification map
    • Buckhaults P, Zhang Z, Chen YC, et al. Identifying tumor origin using a gene expression-based classification map. Cancer Res 2003;63:4144-9.
    • (2003) Cancer Res , vol.63 , pp. 4144-4149
    • Buckhaults, P.1    Zhang, Z.2    Chen, Y.C.3
  • 14
    • 33745839365 scopus 로고    scopus 로고
    • A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
    • Wysocka J, Swigut T, Xiao H, et al. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 2006;442:86-90.
    • (2006) Nature , vol.442 , pp. 86-90
    • Wysocka, J.1    Swigut, T.2    Xiao, H.3
  • 15
    • 0033036185 scopus 로고    scopus 로고
    • Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity
    • Jacobs Y, Schnabel CA, Cleary ML. Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity. Mol Cell Biol 1999;19:5134-42.
    • (1999) Mol Cell Biol , vol.19 , pp. 5134-5142
    • Jacobs, Y.1    Schnabel, C.A.2    Cleary, M.L.3
  • 17
    • 33846303880 scopus 로고    scopus 로고
    • Pre-B-cell leukemia transcription factor 1 is a major target of promyelocytic leukemia zinc-finger-mediated melanoma cell growth suppression
    • Shiraishi K, Yamasaki K, Nanba D, et al. Pre-B-cell leukemia transcription factor 1 is a major target of promyelocytic leukemia zinc-finger-mediated melanoma cell growth suppression. Oncogene 2007;26:339-48.
    • (2007) Oncogene , vol.26 , pp. 339-348
    • Shiraishi, K.1    Yamasaki, K.2    Nanba, D.3
  • 18
    • 0036023971 scopus 로고    scopus 로고
    • A γ-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish
    • Geling A, Steiner H, Willem M, Bally-Cuif L, Haass C. A γ-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish. EMBO Rep 2002;3:688-94.
    • (2002) EMBO Rep , vol.3 , pp. 688-694
    • Geling, A.1    Steiner, H.2    Willem, M.3    Bally-Cuif, L.4    Haass, C.5
  • 19
    • 33947214529 scopus 로고    scopus 로고
    • Notch signaling, γ-secretase inhibitors, and cancer therapy
    • Shih IM, Wang TL. Notch signaling, γ-secretase inhibitors, and cancer therapy. Cancer Res 2007;67:1879-82.
    • (2007) Cancer Res , vol.67 , pp. 1879-1882
    • Shih, I.M.1    Wang, T.L.2
  • 20
    • 0025064238 scopus 로고
    • Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
    • Nourse J, Mellentin JD, Galili N, et al. Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 1990;60:535-45.
    • (1990) Cell , vol.60 , pp. 535-545
    • Nourse, J.1    Mellentin, J.D.2    Galili, N.3
  • 21
    • 0025137176 scopus 로고
    • A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL
    • Kamps MP, Murre C, Sun XH, Baltimore D. A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell 1990;60:547-55.
    • (1990) Cell , vol.60 , pp. 547-555
    • Kamps, M.P.1    Murre, C.2    Sun, X.H.3    Baltimore, D.4
  • 22
    • 22144492615 scopus 로고    scopus 로고
    • Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
    • Minter LM, Turley DM, Das P, et al. Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol 2005;6:680-8.
    • (2005) Nat Immunol , vol.6 , pp. 680-688
    • Minter, L.M.1    Turley, D.M.2    Das, P.3
  • 23
    • 34547780475 scopus 로고    scopus 로고
    • FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
    • O'Neil J, Grim J, Strack P, et al. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors. J Exp Med 2007;204:1813-24.
    • (2007) J Exp Med , vol.204 , pp. 1813-1824
    • O'Neil, J.1    Grim, J.2    Strack, P.3
  • 24
    • 33847083871 scopus 로고    scopus 로고
    • Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling
    • Lewis HD, Leveridge M, Strack PR, et al. Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling. Chem Biol 2007;14:209-19.
    • (2007) Chem Biol , vol.14 , pp. 209-219
    • Lewis, H.D.1    Leveridge, M.2    Strack, P.R.3
  • 25
    • 48649090161 scopus 로고    scopus 로고
    • Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion
    • Choi JH, Park JT, Davidson B, Morin PJ, Shih IM, Wang TL. Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. Cancer Res 2008;68:5716-23.
    • (2008) Cancer Res , vol.68 , pp. 5716-5723
    • Choi, J.H.1    Park, J.T.2    Davidson, B.3    Morin, P.J.4    Shih, I.M.5    Wang, T.L.6
  • 26
    • 0028641294 scopus 로고
    • Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision
    • Wilkinson HA, Fitzgerald K, Greenwald I. Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision. Cell 1994;79:1187-98.
    • (1994) Cell , vol.79 , pp. 1187-1198
    • Wilkinson, H.A.1    Fitzgerald, K.2    Greenwald, I.3
  • 27
    • 0037090983 scopus 로고    scopus 로고
    • Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm
    • Carmena A, Buff E, Halfon MS, et al. Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm. Dev Biol 2002;244:226-42.
    • (2002) Dev Biol , vol.244 , pp. 226-242
    • Carmena, A.1    Buff, E.2    Halfon, M.S.3
  • 28
    • 0030297895 scopus 로고    scopus 로고
    • An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
    • Robey E, Chang D, Itano A, et al. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 1996;87:483-92.
    • (1996) Cell , vol.87 , pp. 483-492
    • Robey, E.1    Chang, D.2    Itano, A.3
  • 29
    • 0029898760 scopus 로고    scopus 로고
    • Extra specificity from extra-denticle: The partnership between HOX and PBX/EXD homeodomain proteins
    • Mann RS, Chan S-K. Extra specificity from extra-denticle: the partnership between HOX and PBX/EXD homeodomain proteins. Trends Genet 1996;12:258.
    • (1996) Trends Genet , vol.12 , pp. 258
    • Mann, R.S.1    Chan, S.-K.2
  • 30
    • 2442575665 scopus 로고    scopus 로고
    • Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential
    • Berkes CA, Bergstrom DA, Penn BH, Seaver KJ, Knoepfler PS, Tapscott SJ. Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential. Mol Cell 2004;14:465.
    • (2004) Mol Cell , vol.14 , pp. 465
    • Berkes, C.A.1    Bergstrom, D.A.2    Penn, B.H.3    Seaver, K.J.4    Knoepfler, P.S.5    Tapscott, S.J.6
  • 31
    • 0034798317 scopus 로고    scopus 로고
    • Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation
    • Selleri L, Depew MJ, Jacobs Y, et al. Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. Development 2001;128:3543-57.
    • (2001) Development , vol.128 , pp. 3543-3557
    • Selleri, L.1    Depew, M.J.2    Jacobs, Y.3
  • 32
    • 0035437164 scopus 로고    scopus 로고
    • The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver
    • DiMartino JF, Selleri L, Traver D, et al. The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver. Blood 2001;98:618-26.
    • (2001) Blood , vol.98 , pp. 618-626
    • DiMartino, J.F.1    Selleri, L.2    Traver, D.3
  • 33
    • 0036544854 scopus 로고    scopus 로고
    • Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus
    • Kim SK, Selleri L, Lee JS, et al. Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus. Nat Genet 2002;30:430.
    • (2002) Nat Genet , vol.30 , pp. 430
    • Kim, S.K.1    Selleri, L.2    Lee, J.S.3
  • 34
    • 0037442838 scopus 로고    scopus 로고
    • Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney
    • Schnabel CA, Godin RE, Cleary ML. Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney. Dev Biol 2003;254:262.
    • (2003) Dev Biol , vol.254 , pp. 262
    • Schnabel, C.A.1    Godin, R.E.2    Cleary, M.L.3
  • 35
    • 34248362004 scopus 로고    scopus 로고
    • B-cell development fails in the absence of the Pbx1 protooncogene
    • Sanyal M, Tung JW, Karsunky H, et al. B-cell development fails in the absence of the Pbx1 protooncogene. Blood 2007;109:4191-9.
    • (2007) Blood , vol.109 , pp. 4191-4199
    • Sanyal, M.1    Tung, J.W.2    Karsunky, H.3
  • 36
    • 0026033596 scopus 로고
    • The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials
    • Kamps MP, Look AT, Baltimore D. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials. Genes Dev 1991;5:358-68.
    • (1991) Genes Dev , vol.5 , pp. 358-368
    • Kamps, M.P.1    Look, A.T.2    Baltimore, D.3
  • 37
    • 0042161874 scopus 로고    scopus 로고
    • Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior
    • LaRonde-LeBlanc NA, Wolberger C. Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior. Genes Dev 2003;17:2060-72.
    • (2003) Genes Dev , vol.17 , pp. 2060-2072
    • LaRonde-LeBlanc, N.A.1    Wolberger, C.2
  • 38
    • 0034598793 scopus 로고    scopus 로고
    • HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis
    • Schnabel CA, Jacobs Y, Cleary ML. HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis. Oncogene 2000;19:608-16.
    • (2000) Oncogene , vol.19 , pp. 608-616
    • Schnabel, C.A.1    Jacobs, Y.2    Cleary, M.L.3
  • 39
    • 36248937213 scopus 로고    scopus 로고
    • Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis
    • Argiropoulos B, Yung E, Humphries RK. Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis. Genes Dev 2007;21:2845-9.
    • (2007) Genes Dev , vol.21 , pp. 2845-2849
    • Argiropoulos, B.1    Yung, E.2    Humphries, R.K.3
  • 40
    • 35948964020 scopus 로고    scopus 로고
    • Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential
    • Wong P, Iwasaki M, Somervaille TC, So CW, Cleary ML. Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential. Genes Dev 2007;21:2762-74.
    • (2007) Genes Dev , vol.21 , pp. 2762-2774
    • Wong, P.1    Iwasaki, M.2    Somervaille, T.C.3    So, C.W.4    Cleary, M.L.5
  • 41
    • 0035909949 scopus 로고    scopus 로고
    • Aberrant expression of homeobox gene HOXA7 is associated with mullerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response
    • Naora H, Montz FJ, Chai CY, Roden RB. Aberrant expression of homeobox gene HOXA7 is associated with mullerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response. Proc Natl Acad Sci U S A 2001;98:15209-14.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 15209-15214
    • Naora, H.1    Montz, F.J.2    Chai, C.Y.3    Roden, R.B.4
  • 42
    • 18344373769 scopus 로고    scopus 로고
    • Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
    • Cheng W, Liu J, Yoshida H, Rosen D, Naora H. Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract. Nat Med 2005;11:531-7.
    • (2005) Nat Med , vol.11 , pp. 531-537
    • Cheng, W.1    Liu, J.2    Yoshida, H.3    Rosen, D.4    Naora, H.5
  • 43
  • 44
    • 20544460148 scopus 로고    scopus 로고
    • Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
    • van Es JH, van Gijn ME, Riccio O, et al. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 2005;435:959-63.
    • (2005) Nature , vol.435 , pp. 959-963
    • van Es, J.H.1    van Gijn, M.E.2    Riccio, O.3


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