Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential

Genes and Development

Volumn 21, Issue 21, 2007, Pages 2762-2774

  Wong, Piu ^a   Iwasaki, Masayuki ^a   Somervaille, Tim C P ^a   So, Chai Wai Eric ^b   Cleary, Michael L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Leukemia stem cells; Meis1; MLL; Pbx; TALE homeodomain proteins

Indexed keywords

HISTONE METHYLTRANSFERASE; HOMEODOMAIN PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; TRANSCRIPTION FACTOR PBX; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL RENEWAL; CELL TRANSFORMATION; CONTROLLED STUDY; GENE; GENE INDUCTION; GENE MUTATION; HOX GENE; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; MALIGNANT TRANSFORMATION; MEIS1 GENE; MOUSE; NONHUMAN; PBX2 GENE; PBX3 GENE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, CDC; HOMEODOMAIN PROTEINS; HUMANS; K562 CELLS; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 35948964020     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1602107     Document Type: Article

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