In vivo mammary tumourigenesis in the Sprague-Dawley rat and microdosimetric correlates

Physics in Medicine and Biology

Volumn 49, Issue 16, 2004, Pages 3817-3830

  Dicello, J F ^a   Christian, A ^b   Cucinotta, F A ^c   Gridley, D S ^d   Kathirithamby, R ^a   Mann, J ^a   Markham, A R ^a   Moyers, M F ^d   Novak, G R ^a   Piantadosi, S ^a   Ricart Arbona, R ^b   Simonson, D M ^a   Strandberg, J D ^b   Vazquez, M ^e   Williams, J R ^a   Zhang, Y ^a   Zhou, H ^a   Huso, D ^b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NASA JOHNSON SPACE CENTER   (United States)

^d LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DATA REDUCTION; ENERGY TRANSFER; IRON; PHOTONS; PROTON IRRADIATION; RISK ASSESSMENT; TUMORS;

LINEAR ENERGY TRANSFER (LET); MAMMARY TUMORS; RADIATION FIELDS;

DOSIMETRY;

ION; IRON; PROTON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC PARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER RISK; CONTROLLED STUDY; CORRELATION ANALYSIS; COSMIC RADIATION; FEMALE; IN VIVO STUDY; LINEAR ENERGY TRANSFER; NONHUMAN; NUCLEON; PARTICLE SIZE; PHOTON; PRIORITY JOURNAL; PROTON RADIATION; RADIATION DOSE; RADIATION ENERGY; RADIATION EXPOSURE; RADIATION FIELD; RAT; RISK ASSESSMENT;

NASA CENTER JSC; NASA DISCIPLINE RADIATION HEALTH; NON-NASA CENTER;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HARDERIAN GLAND; IONS; LINEAR ENERGY TRANSFER; MAMMARY NEOPLASMS, ANIMAL; MODELS, STATISTICAL; NEOPLASMS, RADIATION-INDUCED; PHOTONS; PROTONS; RADIOMETRY; RATS; RATS, SPRAGUE-DAWLEY; RISK; TIME FACTORS;

EID: 4444286001     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/49/16/024     Document Type: Article

References (43)

1. ICRP 1991 1990 Recommendations of the International Commission on Radiological Protection (Oxford: Pergamon)
2. Alpen E L, Powers-Risius P, Curtis S B and DeGuzman R 1993a Tumorigenic potential of high-Z, high-LET charged-particle radiations Radiat. Res. 136 382-91
3. Alpen E L, Powers-Risius P, Curtis S B and DeGuzman R 1993b Tumorigenic potential of high-Z, high-LET charged-particle radiations Radiat. Res. 136 382-91
4. Alpen E L, Powers-Risius P, Curtis S B, DeGuzman R and Fry R J 1994 Fluence-based relative biological effectiveness, for charged particle carcinogenesis in mouse Harderian gland Adv. Space Res. 14 573-81
5. Archambeau J O, Slater J M, Coutrakon G B, Miller D W, Preston W, Slater J D, Dicello J F, Robertson J B and Slater J W 1994 Proton-bearn irradiation for the cancer patient: an approach to optimal therapy and normal-tissue sparing Adv. Radiat. Biol. 18 53-89
6. Bond V P, Cronkite E P, Lippincott S W and Shellabarger C J 1960 Studies on radiation-induced mammary gland neoplasia in the rat Radiat. Res. 2 276-85
7. Brenner D J, Zaider M, Dicello J F and Bichsel H 1991 Theoretical Approaches to Energy Deposition in Small Sites ed Booz J and Ebert H G (Luxembourg: Harwood Academic) pp. 677-88
8. Burns F, Jin Y, Koenig K and Hosselet S 1993 The low carcinogenicity of electron radiation relative to argon ions in rat skin Radiat. Res. 135 178-88
9. Cucinotta F A, Schimmerling W, Wilson J W, Peterson L E, Badhwar G D, Saganti P B and Dicello J F 2001 Space radiation cancer risks and uncertainties for mars missions Radiat. Res. 156 682-88
10. Curtis S B 1996 Possible effects of protracted exposure on the additivity of risks from space radiations Adv. Space Res. 18 41-4
11. Dicello J F 1992a HZE cosmic rays in space: is it possible that they are not the major radiation hazard? Radiat. Prot. Dosim. 44 253-8
12. Dicello J F 1992b HZE cosmic rays in space: is it possible that they are not the major radiation hazard? Radiat. Prot. Dosim. 44 253-8
13. Dicello J F 2002a How do we get from cell and animal data to risks for humans from space radiations? J. Radiat. Res. (Tokyo) (Suppl) 43 S1-S6
14. Dicello J F 2002b How do we get from cell and animal data to risks for humans from space radiations? J. Radiat. Res. (Suppl) 43 S1-S6
15. Dicello J F 2003 The impact of the new biology on radiation risks in space Health Phys. 85 94-102
16. Dicello J F, Schillaci M E and Liu L 1990 Cross sections for pion, neutron, proton and heavy-ion production from 800-meV protons incident upon aluminum and silicon Nucl. Instrum. Methods B 45 135-8
17. Dicello J F, Wasiolek M and Zaider M 1991 Measured microdosimetric spectra of energetic ion beams of Fe, Ar, Ne and C: limitations of LET distributions and quality factor in radiation effects and space research IEEE Trans. Nucl. Sci. 38 1203-9
18. Dicello J F, Zaider M and Varma M N 1994 An inductive assessment of radiation risks in space Adv. Space Res. 14 899-910
19. Fry R J, Powers-Risius P, Alpen E L and Ainsworth E J 1985 High-LET radiation carcinogenesis Radiat. Res. Suppl. 8 S188-S195
20. Johnson J R, Gragtmans N J, Myers D K and Jones A R 1989 Dose-rate effects of mammary tumor development in female Sprague-Dawley rats exposed to x- and gamma-radiation Radiat. Res. 118 545-58
21. National Council on Radiation Protection and Measurements 2001 Fluence-based and microdosimetric event-based methods for radiation protection in space National Council on Radiation Protection and Measurements, Bethesda, MD, NCRP Report 137
22. National Research Council and Committee on the Biological Effects of Ionizing Radiation 1988 Health Risks of Radon and other Internally Deposited Alpha-Emitters: BEIR IV (Washington, DC: National Academy)
23. National Research Council and Committee on the Biological Effects of Ionizing Radiation 1990 Health Eftects of Exposure to Low Levels of Ionizing Radiation: BEIR V (Bethesda, MD: National Academy)
24. National Research Council and Committee on the Biological Effects of Ionizing Radiation 1998 Health Effects of Exposure to Radon: BEIR VI (Bethesda, MD: National Academy)
25. Rodgers R C, Dicello J F and Gross W 1973 The biophysical properties of 3.9-GeV nitrogen ions: II. Microdosimetry Radiat. Res. 54 12-23
26. Russo J, Gusterson B A, Rogers A E, Russo I H, Wellings S R and van Zwieten M J 1990 Comparative study of human and rat mammary tumorigenesis Lab. Invest. 62 244-78
27. Russo I H and Russo J 1978 Developmental stage of the rat mammary gland as determinant of its susceptibility to 7,12-dimethylbenz[a]anthracene J. Natl. Cancer Inst. 61 1439-49
28. Russo J and Russo I H 1980 Influence of differentiation and cell kinetics on the susceptibility of the rat mammary gland to carcinogenesis Cancer Res. 40 2677-87
29. Russo J and Russo I H 2000 Atlas and histologic classification of tumors of the rat mammary gland J. Mammary Gland Biol. Neoplasia 5 5187-200
30. Russo J, Tay L K, Ciocca D R and Russo I H 1983 Molecular and cellular basis of the mammary gland susceptibility to carcinogenesis Environ. Health Perspect. 49 185-99
31. Shellabarger C J, Bond V P, Aponte G E and Cronkite E P 1966 Results of fractionation and protraction of total-body radiation on rat mammary neoplasia Cancer Res. 26 509-13
32. Shellabarger C J, Chmelevsky D and Kellerer A M 1980 Induction of mammary neoplasms in the Sprague-Dawley rat by 430 keV neutrons and x-rays J. Natl. Cancer Inst. 64 821-33
33. Shellabarger C J, Stone J P and Holtzman S 1978a Rat differences in mammary tumor induction with estrogen and neutron radiation J. Natl. Cancer Inst. 61 1505-8
34. Shellabarger C J, Stone J P and Holtzman S 1978b Rat differences in mammary tumor induction with estrogen and neutron radiation J. Natl. Cancer Inst. 61 1505-8
35. Silberberg R, Tsao C H, Adams J H Jr and Letaw J R 1987 Radiation hazards in space Aerosp. Am. 25 38-41
36. Space Studies Board 1996 Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies (Washington, DC: National Academy)
37. U.S. Department of Energy 2002 Low-dose Radiation Research program http://www.er.doe.gov/production/ober/lowdose.html
38. van Zwieten M J, Shellabarger C J, Hollander C F, Cramer D V, Stone J P, Holtzman S and Broerse J J 1984 Differences in DMBA-induced mammary neoplastic responses in two lines of Sprague-Dawley rats Eur. J. Cancer Clin. Oncol. 20 1199-204
39. Vogel H H Jr and Zaldivar R 1972 Neutron-induced mammary neoplasms in the rat Cancer Res. 32 933-8
40. Williams J R, Zhang Y, Zhou H, Osman M, Cha D, Kavet R, Cuccinotta F, Dicello J F and Dillchay L E 1999 Predicting cancer rates in astronauts from animal carcinogenesis studies and cellular markers Mutat. Res. 430 255-69
41. Zaider M 1996 Microdosimetric-based risk factors for radiation received in space activities during a trip to Mars Health Phys. 70 845-51
42. Zeitlin C, Heilbronn L and Miller J 1998 Detailed characterization of the 1087 MeV/nucleon iron-56 beam used for radiobiology at the alternating gradient synchrotron Radiat. Res. 149 560-9
43. Ziegler J F 2004 SRIM-2003 Nucl. Instrum. Methods Phys. Res. B 219-220 1027-36