High linear energy transfer carbon radiation effectively kills cultured glioma cells with either mutant or wild-type p53

International Journal of Radiation Oncology Biology Physics

Volumn 50, Issue 3, 2001, Pages 803-808

  Iwadate, Yasuo ^a   Mizoe, Jun Etsu ^b   Osaka, Yasuhiro ^b   Yamaura, Akira ^a   Tsujii, Hirohiko ^b  

^a CHIBA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Carbon beams; Glioma; Heavy charged particles; p21; p53

Indexed keywords

BIOASSAY; CARBON; CYTOLOGY; GENES; IRRADIATION; MUTAGENESIS; PROTEINS; RADIOTHERAPY; TUMORS; X RAYS;

CYTOTOXIC EFFECTS; RADIORESISTANCE;

ONCOLOGY;

CARBON; PROTEIN BAX; PROTEIN P21; PROTEIN P53;

ARTICLE; BEAM THERAPY; CELL CULTURE; CELL CYCLE; CELL DEATH; CELL LINE; CONTROLLED STUDY; DNA DAMAGE; FLOW CYTOMETRY; GENE MUTATION; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LINEAR ACCELERATOR; LINEAR ENERGY TRANSFER; PARTICLE RADIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; SURVIVAL RATE; TECHNIQUE; WESTERN BLOTTING; X IRRADIATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN NEOPLASMS; CARBON; CELL CYCLE; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA DAMAGE; GLIOMA; HEAVY IONS; HUMANS; LINEAR ENERGY TRANSFER; MUTATION; PARTICLE ACCELERATORS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIOTHERAPY, HIGH-ENERGY; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; X-RAYS;

EID: 0035400225     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(01)01514-0     Document Type: Article

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