Coordinating early kidney development: Lessons from gene targeting

Nature Reviews Genetics

Volumn 3, Issue 7, 2002, Pages 533-543

  Vainio, Seppo ^a   Lin, Yanfeng ^b  

^a UNIVERSITY OF OULU   (Finland)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN;

CELL DIFFERENTIATION; GENE EXPRESSION; GENE INTERACTION; GENE TARGETING; KIDNEY DEVELOPMENT; MESENCHYME CELL; MORPHOGENESIS; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; URETER;

ALLANTOIS; ANIMALS; CHORION; EMBRYONIC AND FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; GENETIC MARKERS; HUMANS; KIDNEY;

EID: 0036303782     PISSN: 14710056     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrg842     Document Type: Review

References (85)

1. Nephron induction revisited: From caps to condensates
2. Origin of glomerular capillaries: Is the verdict in?
3. Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation
4. Multiple roles for the Wilms' tumor suppressor, WT1
5. Mammalian sex determination: From gonads to brain
6. Gene interactions in gonadal development
7. WT1 is required for early kidney development
8. The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin
9. Repression of Pax-2 by WT1 during normal kidney development
10. Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud
11. Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene
12. Renal and neuronal abnormalities in mice lacking GDNF
13. Renal agenesis and the absence of enteric neurons in mice lacking GDNF
14. Defects in erteric innervation and kidney development in mice lacking GDNF
15. GDNF induces branching and increased cell proliferation In the ureter of the mouse
16. Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium
17. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia
18. A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family
19. Murine homolog of SALL 1 is essential for ureteric bud invasion in kidney development
20. Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract
21. The GDNF family: Signalling, biological functions and therapeutic value
22. Expression of the cret proto-oncogene during mouse embryogenesis
23. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
24. GDNF signalling through the Ret receptor tyrosine kinase
25. Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis
26. GFR α1-deficient mice have deficits in the enteric nervous system and kidneys
27. Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis
28. The RET-glial cell-derived neurotrophic factor (GDNF) pathway stimulates migration and chemoattraction of epithelial cells
29. Ureteric bud outgrowth in response to RET activation is mediated by phosphatidylinositol 3-kinase
30. Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis
31. Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter
32. BMP-4 affects the differentiation of metanephric mesenchyme and reveals an early anterior-posterior axis of the embryonic kidney
33. Cellular functions of preteoglycans - An overview
34. Proteoglycans and pattern formation: Sugar biochemistry meets developmental genetics
35. Sulphated proteoglycan is required for collecting duct growth and branching but not nephron formation during kidney development
36. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
37. Molecular cloning and expression of Chinese hamster ovary cell heparan-sulfate 2-sulfotransferase
38. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips
39. -/- mutant mouse
40. Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome
41. Glypicans and the biology of renal malformations
42. Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis
43. Functions of cell surface heparan sulfate proteoglycans
44. Cell surface glypicans are low-affinity endostatin receptors
45. Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
46. Induced repatterning of type XVIII collagen expression in ureter bud from kidney to lung type: Association with sonic hedgehog and ectopic surfactant protein C
47. Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud
48. Molecular regulation of nephron endowment
49. Defects of urogenital development in mice lacking Emx 2
50. New aspects of Wnt signaling pathways in higher vertebrates
51. Heads or tails: Wnts and anterior-posterior patterning
52. Induction of kidney epithelial morphogenesis by cells expressing Wnt-1
53. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
54. A road to kidney tubules via the Wnt pathway
55. Where Notch and Wnt signaling meet. The presenilin hub
56. Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch 2 mutation
57. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
58. Wnt-6 is expressed in the ureter bud and induces kidney tubule development in vitro
59. Frizzled-4 expression during chick kidney development
60. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
61. sFRP-2 is a target of the Wnt-4 signaling pathway in the developing metanephric kidney
62. Secreted Frizzled-related proteins can regulate metanephric development
63. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
64. A genetic hierarchy establishes mitogenic signalling and mitotic competence in the renal tubules of Drosophila
65. Coordinating cell fate and morphogenesis in Drosophila renal tubules
66. Bone morphogenetic proteins in development
67. Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos
68. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
69. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning
70. Bone morphogenetic proteins and skeletal development: The kidney-bone connection
71. Stem cells in the kidney
72. Interaction between FGF and BMP signaling pathways regulates development of metanephric mesenchyme
73. Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2
74. Stromal cells mediate retinoid-dependent functions essential for renal development
75. Vitamin A controls epithelial/mesenchymal interactions through Ret expression
76. FGF-7 modulates ureteric bud growth and nephron number in the developing kidney
77. WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo
78. Induction of ureter branching as a response to Wnt-2b signaling during early kidney organogenesis
79. Pre-pattern in the pronephric kidney field of zebrafish
80. Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
81. Induction of pancreatic differentiation by signals from blood vessels
82. Liver organogenesis promoted by endothelial cells prior to vascular function
83. Changes in global gene expression patterns during development and maturation of the rat kidney
84. Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation