Mitochondrial uncoupling as a potential therapeutic target in acute central nervous system injury

Journal of Neurochemistry

Volumn 91, Issue 2, 2004, Pages 257-262

  Maragos, William F ^a,b,c   Korde, Amit S ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Calcium; Dinitrophenol; Excitotoxicity; Mitochondrial membrane potential; Reactive oxygen species

Indexed keywords

2,4 DINITROPHENOL; ADENOSINE TRIPHOSPHATE; BRAIN MITOCHONDRIAL CARRIER PROTEIN 1; CALCIUM; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; EXCITATORY AMINO ACID; KAINIC ACID; MITOCHONDRIAL PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATASE; PILOCARPINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 4; UNCOUPLING PROTEIN 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; BRAIN MITOCHONDRION; CALCIUM HOMEOSTASIS; CELL SURVIVAL; CONTROLLED STUDY; ELECTRON TRANSPORT; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL UNCOUPLING; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATIVE STRESS; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SEIZURE; SHORT SURVEY; STROKE;

ACUTE DISEASE; ANIMALS; BRAIN INJURIES; CELL SURVIVAL; CEREBROVASCULAR ACCIDENT; HUMANS; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; SPINAL CORD INJURIES; UNCOUPLING AGENTS;

ANIMALIA;

EID: 5444229139     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02736.x     Document Type: Short Survey

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