Paradoxical allosteric effects of competitive inhibitors on neuronal α7 nicotinic receptor mutants

NeuroReport

Volumn 8, Issue 16, 1997, Pages 3591-3596

  Bertrand, Sonia ^a   Devillers Thiéry, Anne ^b   Palma, Eleonora ^a,c   Buisson, Bruno ^a   Edelstein, Stuart J ^a   Corringer, Pierre Jean ^b   Changeux, Jean Pierre ^b   Bertrand, Daniel ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b INSTITUT PASTEUR   (France)

^c REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Acetylcholine; Allosteric model; Competitive antagonists; Ligand gated channels; Nicotine

Indexed keywords

CHOLINERGIC RECEPTOR; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE;

ACETYLCHOLINE BRAIN LEVEL; ALLOSTERISM; ANIMAL CELL; ARTICLE; CHANNEL GATING; DESENSITIZATION; ISOMERISM; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0030710437     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-199711100-00034     Document Type: Article

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