A phosphatidylserine species inhibits a range of TLR- but not IL-1β-induced inflammatory responses by disruption of membrane microdomains

Journal of Immunology

Volumn 181, Issue 8, 2008, Pages 5606-5617

  Parker, Lisa C ^a   Prestwich, Elizabeth C ^a   Ward, Jon R ^a   Smythe, Elizabeth ^b   Berry, Anthony ^c   Triantafilou, Martha ^d   Triantafilou, Kathy ^d   Sabroe, Ian ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c Vaccine Technology Ltd   (United Kingdom)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GARDIQUIMOD; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PHOSPHATIDYLSERINE; POLYINOSINIC POLYCYTIDYLIC ACID; SYNTHETIC PEPTIDE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; PAM(3)CSK(4) PEPTIDE; PEPTIDE;

ARTICLE; CELL EXPANSION; CELL INTERACTION; CELL MEMBRANE; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; INCUBATION TIME; INFLAMMATION; INNATE IMMUNITY; LEUKOCYTE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; TISSUE CULTURE; BIOLOGICAL MODEL; CELL LINE; DRUG EFFECT; DRUG POTENTIATION; IMMUNOLOGY; MONONUCLEAR CELL;

CELL LINE; DOWN-REGULATION; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HUMANS; IMMUNITY, NATURAL; INFLAMMATION; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; MEMBRANE MICRODOMAINS; MODELS, IMMUNOLOGICAL; PEPTIDES; PHOSPHATIDYLSERINES; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; TOLL-LIKE RECEPTORS;

EID: 54049141666     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.8.5606     Document Type: Article

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