HSP70 Enhances Macrophage Phagocytosis by Interaction With Lipid Raft-Associated TLR-7 and Upregulating p38 MAPK and PI3K Pathways

Journal of Surgical Research

Volumn 136, Issue 1, 2006, Pages 58-69

  Wang, Ruibo ^a   Town, Terrence ^b   Gokarn, Varun ^a   Flavell, Richard A ^b,c   Chandawarkar, Rajiv Y ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

heat shock proteins; lipid raft; macrophage activation; p38 MAPk; phagocytosis; PI3K; TLR7

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; HEAT SHOCK PROTEIN 70; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 7; WORTMANNIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LIPID RAFT; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; HSP70 HEAT-SHOCK PROTEINS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHAGOCYTOSIS; RNA; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7; UP-REGULATION;

EID: 33750303979     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2006.06.003     Document Type: Article

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