-
1
-
-
0014941813
-
A theory of self-nonself discrimination
-
(New York)
-
Bretscher P Cohn M A theory of self-nonself discrimination Science (New York) 1970, 169:1042-1049.
-
(1970)
Science
, vol.169
, pp. 1042-1049
-
-
Bretscher, P.1
Cohn, M.2
-
2
-
-
0016336419
-
Allogeneic stimulation modulates the in vitro response of T cells to transplantation antigen
-
Lafferty KJ Misko IS Cooley MA Allogeneic stimulation modulates the in vitro response of T cells to transplantation antigen Nature 1974, 249:275-276.
-
(1974)
Nature
, vol.249
, pp. 275-276
-
-
Lafferty, K.J.1
Misko, I.S.2
Cooley, M.A.3
-
3
-
-
0023143676
-
Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
-
Jenkins MK Schwartz RH Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo J Exp Med 1987, 165:302-319.
-
(1987)
J Exp Med
, vol.165
, pp. 302-319
-
-
Jenkins, M.K.1
Schwartz, R.H.2
-
4
-
-
0028201732
-
Tolerance, danger, and the extended family
-
Matzinger P Tolerance, danger, and the extended family Annu Rev Immunol 1994, 12:991-1045.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 991-1045
-
-
Matzinger, P.1
-
7
-
-
0036484220
-
The B7-CD28 superfamily
-
Sharpe AH Freeman GJ The B7-CD28 superfamily Nat Rev 2002, 2:116-126.
-
(2002)
Nat Rev
, vol.2
, pp. 116-126
-
-
Sharpe, A.H.1
Freeman, G.J.2
-
8
-
-
33745291091
-
Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: A randomized trial
-
Kremer JM Genant HK Moreland LW Russell AS Emery P Abud-Mendoza C Szechinski J Li T Ge Z Becker JC Westhovens R Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: A randomized trial Ann Intern Med 2006, 144:865-876.
-
(2006)
Ann Intern Med
, vol.144
, pp. 865-876
-
-
Kremer, J.M.1
Genant, H.K.2
Moreland, L.W.3
Russell, A.S.4
Emery, P.5
Abud-Mendoza, C.6
Szechinski, J.7
Li, T.8
Ge, Z.9
Becker, J.C.10
Westhovens, R.11
-
9
-
-
38449089414
-
Costimulation blockade: Towards clinical application
-
Weaver TA Charafeddine AH Kirk AD Costimulation blockade: Towards clinical application Front Biosci 2008, 13:2120-2139.
-
(2008)
Front Biosci
, vol.13
, pp. 2120-2139
-
-
Weaver, T.A.1
Charafeddine, A.H.2
Kirk, A.D.3
-
10
-
-
2342452424
-
The regulation of lymphocyte activation by inhibitory receptors
-
Leibson PJ The regulation of lymphocyte activation by inhibitory receptors Curr Opin Immunol 2004, 16:328-336.
-
(2004)
Curr Opin Immunol
, vol.16
, pp. 328-336
-
-
Leibson, P.J.1
-
12
-
-
33748088535
-
Balancing co-stimulation and inhibition with BTLA and HVEM
-
Murphy KM Nelson CA Sedy JR Balancing co-stimulation and inhibition with BTLA and HVEM Nat Rev 2006, 6:671-681.
-
(2006)
Nat Rev
, vol.6
, pp. 671-681
-
-
Murphy, K.M.1
Nelson, C.A.2
Sedy, J.R.3
-
13
-
-
0029031023
-
Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response
-
Lucas PJ Negishi I Nakayama K Fields LE Loh DY Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response J Immunol 1995, 154:5757-5768.
-
(1995)
J Immunol
, vol.154
, pp. 5757-5768
-
-
Lucas, P.J.1
Negishi, I.2
Nakayama, K.3
Fields, L.E.4
Loh, D.Y.5
-
14
-
-
38449115303
-
Expression of CD80/86 on B cells is essential for autoreactive T cell activation and the development of arthritis
-
O'Neill SK Cao Y Hamel KM Doodes PD Hutas G Finnegan A Expression of CD80/86 on B cells is essential for autoreactive T cell activation and the development of arthritis J Immunol 2007, 179:5109-5116.
-
(2007)
J Immunol
, vol.179
, pp. 5109-5116
-
-
O'Neill, S.K.1
Cao, Y.2
Hamel, K.M.3
Doodes, P.D.4
Hutas, G.5
Finnegan, A.6
-
16
-
-
0028500255
-
Absence of B7-dependent responses in CD28-deficient mice
-
Green JM Noel PJ Sperling AI Walunas TL Gray GS Bluestone JA Thompson CB Absence of B7-dependent responses in CD28-deficient mice Immunity 1994, 1:501-508.
-
(1994)
Immunity
, vol.1
, pp. 501-508
-
-
Green, J.M.1
Noel, P.J.2
Sperling, A.I.3
Walunas, T.L.4
Gray, G.S.5
Bluestone, J.A.6
Thompson, C.B.7
-
17
-
-
0027281691
-
Differential T cell costimulatory requirements in CD28-deficient mice
-
Shahinian A Pfeffer K Lee KP Kundig TM Kishihara K Wakeham A Kawai K Ohashi PS Thompson CB Mak TW Differential T cell costimulatory requirements in CD28-deficient mice Science (New York) 1993, 261:609-612.
-
(1993)
Science (New York)
, vol.261
, pp. 609-612
-
-
Shahinian, A.1
Pfeffer, K.2
Lee, K.P.3
Kundig, T.M.4
Kishihara, K.5
Wakeham, A.6
Kawai, K.7
Ohashi, P.S.8
Thompson, C.B.9
Mak, T.W.10
-
18
-
-
20344379893
-
CD28 extinction in human T cells: Altered functions and the program of T-cell senescence
-
Vallejo AN CD28 extinction in human T cells: Altered functions and the program of T-cell senescence Immunol Rev 2005, 205:158-169.
-
(2005)
Immunol Rev
, vol.205
, pp. 158-169
-
-
Vallejo, A.N.1
-
22
-
-
0028790434
-
CD40 ligand-transduced co-stimulation of T cells in the development of helper function
-
van Essen D Kikutani H Gray D CD40 ligand-transduced co-stimulation of T cells in the development of helper function Nature 1995, 378:620-623.
-
(1995)
Nature
, vol.378
, pp. 620-623
-
-
van Essen, D.1
Kikutani, H.2
Gray, D.3
-
23
-
-
0347505003
-
CD28-mediated co-stimulation: A quantitative support for TCR signalling
-
Acuto O Michel F CD28-mediated co-stimulation: A quantitative support for TCR signalling Nat Rev 2003, 3:939-951.
-
(2003)
Nat Rev
, vol.3
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
24
-
-
0036679733
-
It's all Relative: NF-kappaB and CD28 costimulation of T-cell activation
-
Kane LP Lin J Weiss A It's all Relative: NF-kappaB and CD28 costimulation of T-cell activation Trends Immunol 2002, 23:413-420.
-
(2002)
Trends Immunol
, vol.23
, pp. 413-420
-
-
Kane, L.P.1
Lin, J.2
Weiss, A.3
-
25
-
-
0034292369
-
CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation
-
Michel F Mangino G Attal-Bonnefoy G Tuosto L Alcover A Roumier A Olive D Acuto O CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation J Immunol 2000, 165:3820-3829.
-
(2000)
J Immunol
, vol.165
, pp. 3820-3829
-
-
Michel, F.1
Mangino, G.2
Attal-Bonnefoy, G.3
Tuosto, L.4
Alcover, A.5
Roumier, A.6
Olive, D.7
Acuto, O.8
-
26
-
-
0027936441
-
AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes
-
Rincon M Flavell RA AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes EMBO J 1994, 13:4370-4381.
-
(1994)
EMBO J
, vol.13
, pp. 4370-4381
-
-
Rincon, M.1
Flavell, R.A.2
-
28
-
-
0030057218
-
T cell activation determined by T cell receptor number and tunable thresholds
-
Viola A Lanzavecchia A T cell activation determined by T cell receptor number and tunable thresholds Science (New York) 1996, 273:104-106.
-
(1996)
Science (New York)
, vol.273
, pp. 104-106
-
-
Viola, A.1
Lanzavecchia, A.2
-
29
-
-
0037015055
-
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
-
Riley JL Mao M Kobayashi S Biery M Burchard J Cavet G Gregson BP June CH Linsley PS Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors Proc Natl Acad Sci USA 2002, 99:11790-11795.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11790-11795
-
-
Riley, J.L.1
Mao, M.2
Kobayashi, S.3
Biery, M.4
Burchard, J.5
Cavet, G.6
Gregson, B.P.7
June, C.H.8
Linsley, P.S.9
-
30
-
-
0042505740
-
Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists
-
Lühder F Huang Y Dennehy KM Guntermann C Müller I Winkler E Kerkau T Ikemizu S Davis SJ Hanke T Hünig T Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists J Exp Med 2003, 197:955-966.
-
(2003)
J Exp Med
, vol.197
, pp. 955-966
-
-
Lühder, F.1
Huang, Y.2
Dennehy, K.M.3
Guntermann, C.4
Müller, I.5
Winkler, E.6
Kerkau, T.7
Ikemizu, S.8
Davis, S.J.9
Hanke, T.10
Hünig, T.11
-
31
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
Suntharalingam G Perry MR Ward S Brett SJ Castello-Cortes A Brunner MD Panoskaltsis N Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412 N Engl J Med 2006, 355:1018-1028.
-
(2006)
N Engl J Med
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
Brunner, M.D.6
Panoskaltsis, N.7
-
32
-
-
0038578823
-
The PI-3 kinase/Akt pathway and T cell activation: Pleiotropic pathways downstream of PIP3
-
Kane LP Weiss A The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3 Immunol Rev 2003, 192:7-20.
-
(2003)
Immunol Rev
, vol.192
, pp. 7-20
-
-
Kane, L.P.1
Weiss, A.2
-
33
-
-
33947527297
-
Signalling to suit function: Tailoring phosphoinositide 3-kinase during T-cell activation
-
Parry RV Riley JL Ward SG Signalling to suit function: Tailoring phosphoinositide 3-kinase during T-cell activation Trends Immunol 2007, 28:161-168.
-
(2007)
Trends Immunol
, vol.28
, pp. 161-168
-
-
Parry, R.V.1
Riley, J.L.2
Ward, S.G.3
-
35
-
-
0033976064
-
CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression
-
Appleman LJ Berezovskaya A Grass I Boussiotis VA CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression J Immunol 2000, 164:144-151.
-
(2000)
J Immunol
, vol.164
, pp. 144-151
-
-
Appleman, L.J.1
Berezovskaya, A.2
Grass, I.3
Boussiotis, V.A.4
-
36
-
-
0029163387
-
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
-
Boise LH Minn AJ Noel PJ June CH Accavitti MA Lindsten T Thompson CB CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL Immunity 1995, 3:87-98.
-
(1995)
Immunity
, vol.3
, pp. 87-98
-
-
Boise, L.H.1
Minn, A.J.2
Noel, P.J.3
June, C.H.4
Accavitti, M.A.5
Lindsten, T.6
Thompson, C.B.7
-
37
-
-
38449119281
-
+ T cells require CD28 costimulation
-
+ T cells require CD28 costimulation J Immunol 2007, 179:6494-6503.
-
(2007)
J Immunol
, vol.179
, pp. 6494-6503
-
-
Borowski, A.B.1
Boesteanu, A.C.2
Mueller, Y.M.3
Carafides, C.4
Topham, D.J.5
Altman, J.D.6
Jennings, S.R.7
Katsikis, P.D.8
-
38
-
-
40449102228
-
+T cell differentiation by CD80/ CD86-CD28 costimulation and restoration by IL-2 during the recall response
-
+T cell differentiation by CD80/CD86-CD28 costimulation and restoration by IL-2 during the recall response J Immunol 2008, 180:1148-1157.
-
(2008)
J Immunol
, vol.180
, pp. 1148-1157
-
-
Fuse, S.1
Zhang, W.2
Usherwood, E.J.3
-
39
-
-
34247860881
-
Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: A randomized, open-label, parallel group study in healthy subjects
-
Tay L Leon F Vratsanos G Raymond R Corbo M Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: A randomized, open-label, parallel group study in healthy subjects Arthritis Res Ther 2007, 9:R38.
-
(2007)
Arthritis Res Ther
, vol.9
-
-
Tay, L.1
Leon, F.2
Vratsanos, G.3
Raymond, R.4
Corbo, M.5
-
41
-
-
0036481263
-
Epitope spreading in immune-mediated diseases: Implications for immunotherapy
-
Vanderlugt CL Miller SD Epitope spreading in immune-mediated diseases: implications for immunotherapy Nat Rev 2002, 2:85-95.
-
(2002)
Nat Rev
, vol.2
, pp. 85-95
-
-
Vanderlugt, C.L.1
Miller, S.D.2
-
43
-
-
17644389199
-
TNF/TNFR family members in costimulation of T cell responses
-
Watts TH TNF/TNFR family members in costimulation of T cell responses Annu Rev Immunol 2005, 23:23-68.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 23-68
-
-
Watts, T.H.1
-
44
-
-
0242611000
-
CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool
-
Hendriks J Xiao Y Borst J CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool J Exp Med 2003, 198:1369-1380.
-
(2003)
J Exp Med
, vol.198
, pp. 1369-1380
-
-
Hendriks, J.1
Xiao, Y.2
Borst, J.3
-
46
-
-
18244366653
-
Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion
-
Arens R Tesselaar K Baars PA van Schijndel GM Hendriks J Pals ST Krimpenfort P Borst J van Oers MH van Lier RA Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion Immunity 2001, 15:801-812.
-
(2001)
Immunity
, vol.15
, pp. 801-812
-
-
Arens, R.1
Tesselaar, K.2
Baars, P.A.3
van Schijndel, G.M.4
Hendriks, J.5
Pals, S.T.6
Krimpenfort, P.7
Borst, J.8
van Oers, M.H.9
van Lier, R.A.10
-
47
-
-
0034703189
-
Involvement of CD70-CD27 interactions in the induction of experimental autoimmune encephalomyelitis
-
Nakajima A Oshima H Nohara C Morimoto S Yoshino S Kobata T Yagita H Okumura K Involvement of CD70-CD27 interactions in the induction of experimental autoimmune encephalomyelitis J Neuroimmunol 2000, 109:188-196.
-
(2000)
J Neuroimmunol
, vol.109
, pp. 188-196
-
-
Nakajima, A.1
Oshima, H.2
Nohara, C.3
Morimoto, S.4
Yoshino, S.5
Kobata, T.6
Yagita, H.7
Okumura, K.8
-
48
-
-
0037232212
-
Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions
-
Tesselaar K Arens R van Schijndel GM Baars PA Valk van der MA Borst J van Oers MH van Lier RA Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions Nat Immunol 2003, 4:49-54.
-
(2003)
Nat Immunol
, vol.4
, pp. 49-54
-
-
Tesselaar, K.1
Arens, R.2
van Schijndel, G.M.3
Baars, P.A.4
Valk, M.A.5
Borst, J.6
van Oers, M.H.7
van Lier, R.A.8
-
49
-
-
18644376210
-
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs
-
Lu Q Wu A Richardson BC Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs J Immunol 2005, 174:6212-6219.
-
(2005)
J Immunol
, vol.174
, pp. 6212-6219
-
-
Lu, Q.1
Wu, A.2
Richardson, B.C.3
-
50
-
-
34848927650
-
Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis
-
Lee WW Yang ZZ Li G Weyand CM Goronzy JJ Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis J Immunol 2007, 179:2609-2615.
-
(2007)
J Immunol
, vol.179
, pp. 2609-2615
-
-
Lee, W.W.1
Yang, Z.Z.2
Li, G.3
Weyand, C.M.4
Goronzy, J.J.5
-
51
-
-
0031944607
-
CD40 and CD154 in cell-mediated immunity
-
Grewal IS Flavell RA CD40 and CD154 in cell-mediated immunity Annu Rev Immunol 1998, 16:111-135.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 111-135
-
-
Grewal, I.S.1
Flavell, R.A.2
-
52
-
-
0037140551
-
CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis
-
Kang YM Zhang X Wagner UG Yang H Beckenbaugh RD Kurtin PJ Goronzy JJ Weyand CM CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis J Exp Med 2002, 195:1325-1336.
-
(2002)
J Exp Med
, vol.195
, pp. 1325-1336
-
-
Kang, Y.M.1
Zhang, X.2
Wagner, U.G.3
Yang, H.4
Beckenbaugh, R.D.5
Kurtin, P.J.6
Goronzy, J.J.7
Weyand, C.M.8
-
55
-
-
2942718786
-
The role of CD40 ligand in systemic lupus erythematosus
-
Yazdany J Davis J The role of CD40 ligand in systemic lupus erythematosus Lupus 2004, 13:377-380.
-
(2004)
Lupus
, vol.13
, pp. 377-380
-
-
Yazdany, J.1
Davis, J.2
-
56
-
-
0032484987
-
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
-
Henn V Slupsky JR Grafe M Anagnostopoulos I Forster R Muller-Berghaus G Kroczek RA CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells Nature 1998, 391:591-594.
-
(1998)
Nature
, vol.391
, pp. 591-594
-
-
Henn, V.1
Slupsky, J.R.2
Grafe, M.3
Anagnostopoulos, I.4
Forster, R.5
Muller-Berghaus, G.6
Kroczek, R.A.7
-
57
-
-
0036130828
-
CD40L stabilizes arterial thrombi by a beta3 integrin-dependent mechanism
-
Andre P Prasad KS Denis CV He M Papalia JM Hynes RO Phillips DR Wagner DD CD40L stabilizes arterial thrombi by a beta3 integrin-dependent mechanism Nat Med 2002, 8:247-252.
-
(2002)
Nat Med
, vol.8
, pp. 247-252
-
-
Andre, P.1
Prasad, K.S.2
Denis, C.V.3
He, M.4
Papalia, J.M.5
Hynes, R.O.6
Phillips, D.R.7
Wagner, D.D.8
-
59
-
-
2442592797
-
The inducible costimulator plays the major costimulatory role in humoral immune responses in the absence of CD28
-
Suh WK Tafuri A Berg-Brown NN Shahinian A Plyte S Duncan GS Okada H Wakeham A Odermatt B Ohashi PS Mak TW The inducible costimulator plays the major costimulatory role in humoral immune responses in the absence of CD28 J Immunol 2004, 172:5917-5923.
-
(2004)
J Immunol
, vol.172
, pp. 5917-5923
-
-
Suh, W.K.1
Tafuri, A.2
Berg-Brown, N.N.3
Shahinian, A.4
Plyte, S.5
Duncan, G.S.6
Okada, H.7
Wakeham, A.8
Odermatt, B.9
Ohashi, P.S.10
Mak, T.W.11
-
60
-
-
0033696961
-
The CD28-related molecule ICOS is required for effective T cell-dependent immune responses
-
Coyle AJ Lehar S Lloyd C Tian J Delaney T Manning S Nguyen T Burwell T Schneider H Gonzalo JA Gosselin M Owen LR Rudd CE Gutierrez-Ramos JC The CD28-related molecule ICOS is required for effective T cell-dependent immune responses Immunity 2000, 13:95-105.
-
(2000)
Immunity
, vol.13
, pp. 95-105
-
-
Coyle, A.J.1
Lehar, S.2
Lloyd, C.3
Tian, J.4
Delaney, T.5
Manning, S.6
Nguyen, T.7
Burwell, T.8
Schneider, H.9
Gonzalo, J.A.10
Gosselin, M.11
Owen, L.R.12
Rudd, C.E.13
Gutierrez-Ramos, J.C.14
-
61
-
-
12344286127
-
Emerging mechanisms of immune regulation: The extended B7 family and regulatory T cells
-
Loke P Allison JP Emerging mechanisms of immune regulation: The extended B7 family and regulatory T cells Arthritis Res Ther 2004, 6:208-214.
-
(2004)
Arthritis Res Ther
, vol.6
, pp. 208-214
-
-
Loke, P.1
Allison, J.P.2
-
63
-
-
0034922160
-
The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
-
Rottman JB Smith T Tonra JR Ganley K Bloom T Silva R Pierce B Gutierrez-Ramos JC Ozkaynak E Coyle AJ The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE Nat Immunol 2001, 2:605-611.
-
(2001)
Nat Immunol
, vol.2
, pp. 605-611
-
-
Rottman, J.B.1
Smith, T.2
Tonra, J.R.3
Ganley, K.4
Bloom, T.5
Silva, R.6
Pierce, B.7
Gutierrez-Ramos, J.C.8
Ozkaynak, E.9
Coyle, A.J.10
-
64
-
-
5844252552
-
B7-H3: A costimulatory molecule for T cell activation and IFN-gamma production
-
Chapoval AI Ni J Lau JS Wilcox RA Flies DB Liu D Dong H Sica GL Zhu G Tamada K Chen L B7-H3: A costimulatory molecule for T cell activation and IFN-gamma production Nat Immunol 2001, 2:269-274.
-
(2001)
Nat Immunol
, vol.2
, pp. 269-274
-
-
Chapoval, A.I.1
Ni, J.2
Lau, J.S.3
Wilcox, R.A.4
Flies, D.B.5
Liu, D.6
Dong, H.7
Sica, G.L.8
Zhu, G.9
Tamada, K.10
Chen, L.11
-
65
-
-
0032955192
-
Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: Amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein
-
Higgins LM McDonald SA Whittle N Crockett N Shields JG MacDonald TT Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: Amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein J Immunol 1999, 162:486-493.
-
(1999)
J Immunol
, vol.162
, pp. 486-493
-
-
Higgins, L.M.1
McDonald, S.A.2
Whittle, N.3
Crockett, N.4
Shields, J.G.5
MacDonald, T.T.6
-
66
-
-
0035337241
-
CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice
-
Malmstrom V Shipton D Singh B Al-Shamkhani A Puklavec MJ Barclay AN Powrie F CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice J Immunol 2001, 166:6972-6981.
-
(2001)
J Immunol
, vol.166
, pp. 6972-6981
-
-
Malmstrom, V.1
Shipton, D.2
Singh, B.3
Al-Shamkhani, A.4
Puklavec, M.J.5
Barclay, A.N.6
Powrie, F.7
-
67
-
-
0035451519
-
Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis
-
Ndhlovu LC Ishii N Murata K Sato T Sugamura K Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis J Immunol 2001, 167:2991-2999.
-
(2001)
J Immunol
, vol.167
, pp. 2991-2999
-
-
Ndhlovu, L.C.1
Ishii, N.2
Murata, K.3
Sato, T.4
Sugamura, K.5
-
68
-
-
0033083303
-
Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis
-
Weinberg AD Wegmann KW Funatake C Whitham RH Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis J Immunol 1999, 162:1818-1826.
-
(1999)
J Immunol
, vol.162
, pp. 1818-1826
-
-
Weinberg, A.D.1
Wegmann, K.W.2
Funatake, C.3
Whitham, R.H.4
-
69
-
-
0033785481
-
Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis
-
Yoshioka T Nakajima A Akiba H Ishiwata T Asano G Yoshino S Yagita H Okumura K Contribution of OX40/OX40 ligand interaction to the pathogenesis of rheumatoid arthritis Eur J Immunol 2000, 30:2815-20823.
-
(2000)
Eur J Immunol
, vol.30
, pp. 2815-2823
-
-
Yoshioka, T.1
Nakajima, A.2
Akiba, H.3
Ishiwata, T.4
Asano, G.5
Yoshino, S.6
Yagita, H.7
Okumura, K.8
-
70
-
-
3042658705
-
Anti-CD137 antibodies in the treatment of autoimmune disease and cancer
-
Mittler RS Foell J McCausland M Strahotin S Niu L Bapat A Hewes LB Anti-CD137 antibodies in the treatment of autoimmune disease and cancer Immunol Res 2004, 29:197-208.
-
(2004)
Immunol Res
, vol.29
, pp. 197-208
-
-
Mittler, R.S.1
Foell, J.2
McCausland, M.3
Strahotin, S.4
Niu, L.5
Bapat, A.6
Hewes, L.B.7
-
71
-
-
22444432047
-
Interfacing T-cell effector and regulatory function through CD137 (4-1BB) co-stimulation
-
Myers LM Vella AT Interfacing T-cell effector and regulatory function through CD137 (4-1BB) co-stimulation Trends Immunol 2005, 26:440-446.
-
(2005)
Trends Immunol
, vol.26
, pp. 440-446
-
-
Myers, L.M.1
Vella, A.T.2
-
72
-
-
0033711184
-
The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137
-
Lyons PA Hancock WW Denny P Lord CJ Hill NJ Armitage N Siegmund T Todd JA Phillips MS Hess JF Chen SL Fischer PA Peterson LB Wicker LS The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137 Immunity 2000, 13:107-115.
-
(2000)
Immunity
, vol.13
, pp. 107-115
-
-
Lyons, P.A.1
Hancock, W.W.2
Denny, P.3
Lord, C.J.4
Hill, N.J.5
Armitage, N.6
Siegmund, T.7
Todd, J.A.8
Phillips, M.S.9
Hess, J.F.10
Chen, S.L.11
Fischer, P.A.12
Peterson, L.B.13
Wicker, L.S.14
-
73
-
-
1542615649
-
Inhibitory NK-cell receptors on T cells: Witness of the past, actors of the future
-
Vivier E Anfossi N Inhibitory NK-cell receptors on T cells: Witness of the past, actors of the future Nat Rev 2004, 4:190-198.
-
(2004)
Nat Rev
, vol.4
, pp. 190-198
-
-
Vivier, E.1
Anfossi, N.2
-
74
-
-
0035869455
-
Differential expression of leukocyte receptor complex-encoded Ig-like receptors correlates with the transition from effector to memory CTL
-
Young NT Uhrberg M Phillips JH Lanier LL Parham P Differential expression of leukocyte receptor complex-encoded Ig-like receptors correlates with the transition from effector to memory CTL J Immunol 2001, 166:3933-3941.
-
(2001)
J Immunol
, vol.166
, pp. 3933-3941
-
-
Young, N.T.1
Uhrberg, M.2
Phillips, J.H.3
Lanier, L.L.4
Parham, P.5
-
75
-
-
40849145398
-
T cell subset-specific susceptibility to aging
-
Czesnikiewicz-Guzik M Lee WW Cui D Hiruma Y Lamar DL Yang ZZ Ouslander JG Weyand CM Goronzy JJ T cell subset-specific susceptibility to aging Clin Immunol (Orlando, FL) 2008, 127:107-118.
-
(2008)
Clin Immunol (Orlando, FL)
, vol.127
, pp. 107-118
-
-
Czesnikiewicz-Guzik, M.1
Lee, W.W.2
Cui, D.3
Hiruma, Y.4
Lamar, D.L.5
Yang, Z.Z.6
Ouslander, J.G.7
Weyand, C.M.8
Goronzy, J.J.9
-
76
-
-
33744484987
-
Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors
-
Henel G Singh K Cui D Pryshchep S Lee WW Weyand CM Goronzy JJ Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors Blood 2006, 107:4449-4457.
-
(2006)
Blood
, vol.107
, pp. 4449-4457
-
-
Henel, G.1
Singh, K.2
Cui, D.3
Pryshchep, S.4
Lee, W.W.5
Weyand, C.M.6
Goronzy, J.J.7
-
77
-
-
0345772230
-
The double life of NK receptors: Stimulation or co-stimulation?
-
Snyder MR Weyand CM Goronzy JJ The double life of NK receptors: stimulation or co-stimulation? Trends Immunol 2004, 25:25-32.
-
(2004)
Trends Immunol
, vol.25
, pp. 25-32
-
-
Snyder, M.R.1
Weyand, C.M.2
Goronzy, J.J.3
-
78
-
-
28544438330
-
Role of ITAM-containing adapter proteins and their receptors in the immune system and bone
-
Humphrey MB Lanier LL Nakamura MC Role of ITAM-containing adapter proteins and their receptors in the immune system and bone Immunol Rev 2005, 208:50-65.
-
(2005)
Immunol Rev
, vol.208
, pp. 50-65
-
-
Humphrey, M.B.1
Lanier, L.L.2
Nakamura, M.C.3
-
79
-
-
4644239414
-
Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms
-
Snyder MR Nakajima T Leibson PJ Weyand CM Goronzy JJ Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms J Immunol 2004, 173:3725-3731.
-
(2004)
J Immunol
, vol.173
, pp. 3725-3731
-
-
Snyder, M.R.1
Nakajima, T.2
Leibson, P.J.3
Weyand, C.M.4
Goronzy, J.J.5
-
80
-
-
0037450682
-
Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4+ T cells
-
Snyder MR Lucas M Vivier E Weyand CM Goronzy JJ Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4+ T cells J Exp Med 2003, 197:437-449.
-
(2003)
J Exp Med
, vol.197
, pp. 437-449
-
-
Snyder, M.R.1
Lucas, M.2
Vivier, E.3
Weyand, C.M.4
Goronzy, J.J.5
-
81
-
-
17144363242
-
Understanding how combinations of HLA and KIR genes influence disease
-
Rajagopalan S Long EO Understanding how combinations of HLA and KIR genes influence disease J Exp Med 2005, 201:1025-1029.
-
(2005)
J Exp Med
, vol.201
, pp. 1025-1029
-
-
Rajagopalan, S.1
Long, E.O.2
-
82
-
-
0035927054
-
Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis
-
Yen JH Moore BE Nakajima T Scholl D Schaid DJ Weyand CM Goronzy JJ Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis J Exp Med 2001, 193:1159-1167.
-
(2001)
J Exp Med
, vol.193
, pp. 1159-1167
-
-
Yen, J.H.1
Moore, B.E.2
Nakajima, T.3
Scholl, D.4
Schaid, D.J.5
Weyand, C.M.6
Goronzy, J.J.7
-
83
-
-
0031026454
-
Costimulation of T cell activation by integrin-associated protein (CD47) is an adhesion-dependent, CD28-independent signaling pathway
-
Reinhold MI Lindberg FP Kersh GJ Allen PM Brown EJ Costimulation of T cell activation by integrin-associated protein (CD47) is an adhesion-dependent, CD28-independent signaling pathway J Exp Med 1997, 185:1-11.
-
(1997)
J Exp Med
, vol.185
, pp. 1-11
-
-
Reinhold, M.I.1
Lindberg, F.P.2
Kersh, G.J.3
Allen, P.M.4
Brown, E.J.5
-
84
-
-
9644264253
-
Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis
-
Park YW Kang YM Butterfield J Detmar M Goronzy JJ Weyand CM Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis Am J Pathol 2004, 165:2087-2098.
-
(2004)
Am J Pathol
, vol.165
, pp. 2087-2098
-
-
Park, Y.W.1
Kang, Y.M.2
Butterfield, J.3
Detmar, M.4
Goronzy, J.J.5
Weyand, C.M.6
-
85
-
-
0343484319
-
Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells
-
Vallejo AN Mugge LO Klimiuk PA Weyand CM Goronzy JJ Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells J Immunol 2000, 164:2947-2954.
-
(2000)
J Immunol
, vol.164
, pp. 2947-2954
-
-
Vallejo, A.N.1
Mugge, L.O.2
Klimiuk, P.A.3
Weyand, C.M.4
Goronzy, J.J.5
-
86
-
-
0042591425
-
Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction
-
Vallejo AN Yang H Klimiuk PA Weyand CM Goronzy JJ Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction J Immunol 2003, 171:1732-1740.
-
(2003)
J Immunol
, vol.171
, pp. 1732-1740
-
-
Vallejo, A.N.1
Yang, H.2
Klimiuk, P.A.3
Weyand, C.M.4
Goronzy, J.J.5
-
88
-
-
33745491185
-
Costimulatory pathways in rheumatoid synovitis and T-cell senescence
-
Goronzy JJ Henel G Sawai H Singh K Lee EB Pryshchep S Weyand CM Costimulatory pathways in rheumatoid synovitis and T-cell senescence Ann N Y Acad Sci 2005, 1062:182-194.
-
(2005)
Ann N Y Acad Sci
, vol.1062
, pp. 182-194
-
-
Goronzy, J.J.1
Henel, G.2
Sawai, H.3
Singh, K.4
Lee, E.B.5
Pryshchep, S.6
Weyand, C.M.7
-
89
-
-
0041422233
-
Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis
-
Groh V Bruhl A El-Gabalawy H Nelson JL Spies T Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis Proc Natl Acad Sci USA 2003, 100:9452-9457.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9452-9457
-
-
Groh, V.1
Bruhl, A.2
El-Gabalawy, H.3
Nelson, J.L.4
Spies, T.5
-
90
-
-
33744545472
-
NKG2D-mediated activation of cytotoxic lymphocytes: Unique signaling pathways and distinct functional outcomes
-
Upshaw JL Leibson PJ NKG2D-mediated activation of cytotoxic lymphocytes: unique signaling pathways and distinct functional outcomes Semin Immunol 2006, 18:167-175.
-
(2006)
Semin Immunol
, vol.18
, pp. 167-175
-
-
Upshaw, J.L.1
Leibson, P.J.2
-
92
-
-
35348822056
-
Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis
-
Sawai H Park YW He X Goronzy JJ Weyand CM Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis Arthritis Rheum 2007, 56:3215-3225.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3215-3225
-
-
Sawai, H.1
Park, Y.W.2
He, X.3
Goronzy, J.J.4
Weyand, C.M.5
|