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Volumn 780, Issue 2, 1998, Pages 294-303

Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease

Author keywords

Acetylcholine; Alzheimer's disease; Basal forebrain; Model; Neuroinflammation; Rat

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0032509740     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01215-8     Document Type: Article
Times cited : (303)

References (58)
  • 1
    • 0028103819 scopus 로고
    • Inflammatory mechanisms in Alzheimer's disease: Implications for therapy
    • Aisen P.S., Davis K.L. Inflammatory mechanisms in Alzheimer's disease: implications for therapy. Am. J. Psychiat. 151:1994;1105-1113.
    • (1994) Am. J. Psychiat. , vol.151 , pp. 1105-1113
    • Aisen, P.S.1    Davis, K.L.2
  • 3
    • 0023923989 scopus 로고
    • Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease
    • Allen S.J., Dawbarn D., Wilcock G.K. Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease. Brain Res. 454:1988;275-281.
    • (1988) Brain Res. , vol.454 , pp. 275-281
    • Allen, S.J.1    Dawbarn, D.2    Wilcock, G.K.3
  • 5
    • 0025763298 scopus 로고
    • Interleukin-6 and α2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices
    • Bauer J., Strauss S., Schreiter-Gasser U., Schlegel P., Witt I., Yolk B., Berger M. Interleukin-6 and α2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices. FEBS Lett. 285:1991;111-114.
    • (1991) FEBS Lett. , vol.285 , pp. 111-114
    • Bauer, J.1    Strauss, S.2    Schreiter-Gasser, U.3    Schlegel, P.4    Witt, I.5    Yolk, B.6    Berger, M.7
  • 6
    • 0028301626 scopus 로고
    • Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis
    • Berger-Sweeney J., Heckers S., Mesulam M.-M., Wiley R.G., Lapp D.A., Sharma M. Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis. J. Neurosci. 14:1994;4507-4519.
    • (1994) J. Neurosci. , vol.14 , pp. 4507-4519
    • Berger-Sweeney, J.1    Heckers, S.2    Mesulam, M.-M.3    Wiley, R.G.4    Lapp, D.A.5    Sharma, M.6
  • 9
    • 0026599095 scopus 로고
    • Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat
    • Bluthe R.-M., Dantzer R., Kelley K.W. Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat. Brain Res. 573:1992;318-320.
    • (1992) Brain Res. , vol.573 , pp. 318-320
    • Bluthe, R.-M.1    Dantzer, R.2    Kelley, K.W.3
  • 10
    • 0028289083 scopus 로고
    • Inverse association of anti-inflammatory treatments and Alzheimer's disease: Initial results of a co-twin control study
    • Breitner J.C., Gav B.A., Welsh K.A., Plassman B.L., McDonald W.M., Helms M.J. Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study. Neurology. 44:1994;227-232.
    • (1994) Neurology , vol.44 , pp. 227-232
    • Breitner, J.C.1    Gav, B.A.2    Welsh, K.A.3    Plassman, B.L.4    McDonald, W.M.5    Helms, M.J.6
  • 12
    • 0030580435 scopus 로고    scopus 로고
    • Delayed, selective neuronal death following experimental cortical impact injury in rats: Possible role in memory deficits
    • Colicos M.A., Dixon C.E., Dash P.K. Delayed, selective neuronal death following experimental cortical impact injury in rats: possible role in memory deficits. Brain Res. 739:1996;111-119.
    • (1996) Brain Res. , vol.739 , pp. 111-119
    • Colicos, M.A.1    Dixon, C.E.2    Dash, P.K.3
  • 13
    • 0027197191 scopus 로고
    • Detection of NGF-like activity in human brain tissue: Increased levels in Alzheimer's disease
    • Crutcher K.A., Scott S.A., Liang S., Everson W.V., Weingartner J. Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease. J. Neurosci. 13:1993;2540-2550.
    • (1993) J. Neurosci. , vol.13 , pp. 2540-2550
    • Crutcher, K.A.1    Scott, S.A.2    Liang, S.3    Everson, W.V.4    Weingartner, J.5
  • 14
    • 0027314268 scopus 로고
    • Molecular profile of reactive astrocytes - Implications for their role in neurologic disease
    • Eddleston M., Mucke L. Molecular profile of reactive astrocytes - implications for their role in neurologic disease. Neuroscience. 54:1993;15-36.
    • (1993) Neuroscience , vol.54 , pp. 15-36
    • Eddleston, M.1    Mucke, L.2
  • 16
    • 0027367360 scopus 로고
    • A novel approach to screen for cytokine effects on neuronal gene expression
    • Fann M.-J., Patterson P.H. A novel approach to screen for cytokine effects on neuronal gene expression. J. Neurochem. 61:1993;1349-1355.
    • (1993) J. Neurochem. , vol.61 , pp. 1349-1355
    • Fann, M.-J.1    Patterson, P.H.2
  • 17
    • 0027354292 scopus 로고
    • Microglia MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus
    • Finsen B.R., Jorgensen M.B., Zimmer J. Microglia MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus. Glia. 7:1993;41-49.
    • (1993) Glia , vol.7 , pp. 41-49
    • Finsen, B.R.1    Jorgensen, M.B.2    Zimmer, J.3
  • 18
    • 0027345355 scopus 로고
    • Characterization of microglia and macrophages in the central nervous system of rats: Definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction
    • Flaris N.A., Densmore T.L., Molleston M.C., Hickey W.F. Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction. Glia. 7:1993;34-40.
    • (1993) Glia , vol.7 , pp. 34-40
    • Flaris, N.A.1    Densmore, T.L.2    Molleston, M.C.3    Hickey, W.F.4
  • 19
    • 0014602871 scopus 로고
    • Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities
    • Fonnum F. Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities. Biochem. J. 115:1969;465-472.
    • (1969) Biochem. J. , vol.115 , pp. 465-472
    • Fonnum, F.1
  • 20
    • 0027978247 scopus 로고
    • New opportunities in AD research - Roles of immunoinflammatory responses and glia
    • Frederickson R.C.A., Brunden K.R. New opportunities in AD research - roles of immunoinflammatory responses and glia. Alz. Dis. Assoc. Dis. 8:1994;159-165.
    • (1994) Alz. Dis. Assoc. Dis. , vol.8 , pp. 159-165
    • Frederickson, R.C.A.1    Brunden, K.R.2
  • 23
    • 0027970725 scopus 로고
    • Lateral cortical impact injury in rats: Pathological effects of varying cortical compression and impact velocity
    • Goodman J.C., Cherian L., Bryan R.M. Jr., Robertson C.S. Lateral cortical impact injury in rats: pathological effects of varying cortical compression and impact velocity. J. Neurotrauma. 11:1994;587-597.
    • (1994) J. Neurotrauma , vol.11 , pp. 587-597
    • Goodman, J.C.1    Cherian, L.2    Bryan R.M., Jr.3    Robertson, C.S.4
  • 24
    • 0028167986 scopus 로고
    • Microglial interleukin-1 alpha expression in human head injury: Correlations with neuronal and neuritic beta-amyloid precursor protein expression
    • Griffin W.S.T., Sheng J.G., Gentleman S.M., Graham D.I., Mrak R.E., Roberts G.W. Microglial interleukin-1 alpha expression in human head injury: correlations with neuronal and neuritic beta-amyloid precursor protein expression. Neurosci. Lett. 176:1994;133-136.
    • (1994) Neurosci. Lett. , vol.176 , pp. 133-136
    • Griffin, W.S.T.1    Sheng, J.G.2    Gentleman, S.M.3    Graham, D.I.4    Mrak, R.E.5    Roberts, G.W.6
  • 27
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy J.A., Higgins G.A. Alzheimer's disease: the amyloid cascade hypothesis. Science. 256:1992;184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 28
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hoffman F.M., Hinton D.R., Johnson K., Merrill J.E. Tumor necrosis factor identified in multiple sclerosis brain. J. Exp. Med. 170:1989;607-612.
    • (1989) J. Exp. Med. , vol.170 , pp. 607-612
    • Hoffman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 29
    • 0021145680 scopus 로고
    • Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation
    • Hyman B.T., Van Hoesen G.W., Damasio A.R., Barnes C.L. Alzheimer's disease: cell-specific pathology isolates the hippocampal formation. Science. 225:1984;1168-1170.
    • (1984) Science , vol.225 , pp. 1168-1170
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3    Barnes, C.L.4
  • 30
    • 0027257348 scopus 로고
    • On the role of the hippocampus in learning and memory in the rat
    • Jarrard L.E. On the role of the hippocampus in learning and memory in the rat. Behav. Neural Biol. 60:1993;9-26.
    • (1993) Behav. Neural Biol. , vol.60 , pp. 9-26
    • Jarrard, L.E.1
  • 31
    • 15844414671 scopus 로고    scopus 로고
    • Nerve growth factor and cytokines mediate lymphoid tissue-induced neurite outgrowth from mouse superior cervical ganglia in vitro
    • Kannan Y., Bienenstock J., Ohta M., Stanisz A.M., Stead R.H. Nerve growth factor and cytokines mediate lymphoid tissue-induced neurite outgrowth from mouse superior cervical ganglia in vitro. J. Immunol. 156:1996;313-320.
    • (1996) J. Immunol. , vol.156 , pp. 313-320
    • Kannan, Y.1    Bienenstock, J.2    Ohta, M.3    Stanisz, A.M.4    Stead, R.H.5
  • 32
    • 0028618486 scopus 로고
    • Cytokines as regulators of sleep
    • Krueger J.M., Toth L.A. Cytokines as regulators of sleep. Ann. NY Acad. Sci. 739:1994;299-310.
    • (1994) Ann. NY Acad. Sci. , vol.739 , pp. 299-310
    • Krueger, J.M.1    Toth, L.A.2
  • 34
    • 0028338306 scopus 로고
    • Pathological correlates of dementia in Alzheimer's disease
    • Mann D.M.A. Pathological correlates of dementia in Alzheimer's disease. Neurobiol. Aging. 15:1994;357-360.
    • (1994) Neurobiol. Aging , vol.15 , pp. 357-360
    • Mann, D.M.A.1
  • 35
    • 0030961544 scopus 로고    scopus 로고
    • Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia
    • McDonald D., Brunden K., Landreth G. Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia. J. Neurosci. 17:1997;2284-2294.
    • (1997) J. Neurosci. , vol.17 , pp. 2284-2294
    • McDonald, D.1    Brunden, K.2    Landreth, G.3
  • 37
    • 0021246085 scopus 로고
    • Aging, Alzheimer's disease and the cholinergic system of the basal forebrain
    • McGeer P.L., McGeer E.G., Suzuki J., Dolman C.E., Nagai T. Aging, Alzheimer's disease and the cholinergic system of the basal forebrain. Neurology. 34:1984;741-745.
    • (1984) Neurology , vol.34 , pp. 741-745
    • McGeer, P.L.1    McGeer, E.G.2    Suzuki, J.3    Dolman, C.E.4    Nagai, T.5
  • 38
    • 0029161781 scopus 로고
    • Glial cytokines in Alzheimer's disease: Review and pathogenic implications
    • Mrak R.E., Sheng J.G., Griffin W.S.T. Glial cytokines in Alzheimer's disease: review and pathogenic implications. Human Pathol. 26:1995;816-823.
    • (1995) Human Pathol. , vol.26 , pp. 816-823
    • Mrak, R.E.1    Sheng, J.G.2    Griffin, W.S.T.3
  • 39
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • Morris R.G.M., Garrud P., Rawlins P., O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature. 297:1982;681-683.
    • (1982) Nature , vol.297 , pp. 681-683
    • Morris, R.G.M.1    Garrud, P.2    Rawlins, P.3    O'Keefe, J.4
  • 41
    • 0002083998 scopus 로고
    • Dementia: animal models of the cognitive impairments produced by degeneration of the basal forebrain cholinergic system
    • in: H.Y. Meltzer (Ed.), Raven Press, New York
    • D.S. Olton, G.L. Wenk, Dementia: animal models of the cognitive impairments produced by degeneration of the basal forebrain cholinergic system, in: H.Y. Meltzer (Ed.), Psychopharmacology: The Third Generation of Progress, Raven Press, New York, 1987, pp. 941-953.
    • (1987) Psychopharmacology: The Third Generation of Progress , pp. 941-953
    • Olton, D.S.1    Wenk, G.L.2
  • 42
    • 0027352040 scopus 로고
    • Altered antigen expression of microglia in the aged rodent CNS
    • Perry V.H., Matyszak M.K., Fearn S. Altered antigen expression of microglia in the aged rodent CNS. Glia. 7:1993;60-67.
    • (1993) Glia , vol.7 , pp. 60-67
    • Perry, V.H.1    Matyszak, M.K.2    Fearn, S.3
  • 43
    • 0027447286 scopus 로고
    • Neurodegeneration induced by beta-amyloid peptides in vitro: The role of peptide assembly state
    • Pike C.J., Burdick D., Walencewicz A.J., Glabe C.G., Cotman C.W. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13:1993;1676-1687.
    • (1993) J. Neurosci. , vol.13 , pp. 1676-1687
    • Pike, C.J.1    Burdick, D.2    Walencewicz, A.J.3    Glabe, C.G.4    Cotman, C.W.5
  • 44
    • 0028639536 scopus 로고
    • Tangles and plaques in healthy aging and Alzheimer's disease: Independence or interaction?
    • Price J.L. Tangles and plaques in healthy aging and Alzheimer's disease: independence or interaction? Sem. Neurosci. 6:1994;395-402.
    • (1994) Sem. Neurosci. , vol.6 , pp. 395-402
    • Price, J.L.1
  • 45
    • 0028314343 scopus 로고
    • Induction of interleukin-1 in various brain regions after peripheral and central injections of lipopolysaccharide
    • Quan N., Sundar S.K., Weiss J. Induction of interleukin-1 in various brain regions after peripheral and central injections of lipopolysaccharide. J. Neuroimmunol. 49:1994;125-134.
    • (1994) J. Neuroimmunol. , vol.49 , pp. 125-134
    • Quan, N.1    Sundar, S.K.2    Weiss, J.3
  • 47
    • 0023176143 scopus 로고
    • Neuronal size and density in the nucleus basalis of Meynert in Alzheimer's disease
    • Rinne J.O., Paljarvi L., Rinne K. Neuronal size and density in the nucleus basalis of Meynert in Alzheimer's disease. J. Neuronal Sci. 79:1987;67-76.
    • (1987) J. Neuronal Sci. , vol.79 , pp. 67-76
    • Rinne, J.O.1    Paljarvi, L.2    Rinne, K.3
  • 50
    • 0025753852 scopus 로고
    • The molecular pathology of Alzheimer's disease
    • Selkoe D.J. The molecular pathology of Alzheimer's disease. Neuron. 6:1991;487-498.
    • (1991) Neuron , vol.6 , pp. 487-498
    • Selkoe, D.J.1
  • 51
    • 0007692414 scopus 로고    scopus 로고
    • In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis
    • Sheng J.G., Ito K., Skinner R.D., Mrak R.E., Rovnaghi C.R., Van Eldik L.J., Griffin S.T. In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis. Neurobiol. Aging. 17:1996;761-766.
    • (1996) Neurobiol. Aging , vol.17 , pp. 761-766
    • Sheng, J.G.1    Ito, K.2    Skinner, R.D.3    Mrak, R.E.4    Rovnaghi, C.R.5    Van Eldik, L.J.6    Griffin, S.T.7
  • 53
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry R.D., Masliah E., Salmon D.P., Butters N., DeTeresa R., Hill R., Hansen L.A., Katzman R. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann. Neurol. 30:1991;572-580.
    • (1991) Ann. Neurol. , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    Deteresa, R.5    Hill, R.6    Hansen, L.A.7    Katzman, R.8
  • 55
    • 0027087240 scopus 로고
    • Basal forebrain neurons and memory: A biochemical, histological and behavioral study of differential vulnerability to ibotenate and quisqualate
    • Wenk G.L., Harrington C.A., Walker L.C., Tucker D.A., Rance N.E. Basal forebrain neurons and memory: a biochemical, histological and behavioral study of differential vulnerability to ibotenate and quisqualate. Behav. Neurosci. 106:1992;909-923.
    • (1992) Behav. Neurosci. , vol.106 , pp. 909-923
    • Wenk, G.L.1    Harrington, C.A.2    Walker, L.C.3    Tucker, D.A.4    Rance, N.E.5
  • 57
    • 0028000993 scopus 로고
    • Behavioral, biochemical, histological and electrophysiological effects of 192 IgG-saporin injections into the basal forebrain of rats
    • Wenk G.L., Stoehr J.D., Quintana G., Mobley S.L., Wiley R.G. Behavioral, biochemical, histological and electrophysiological effects of 192 IgG-saporin injections into the basal forebrain of rats. J. Neurosci. 14:1994;5986-5995.
    • (1994) J. Neurosci. , vol.14 , pp. 5986-5995
    • Wenk, G.L.1    Stoehr, J.D.2    Quintana, G.3    Mobley, S.L.4    Wiley, R.G.5
  • 58
    • 0021803045 scopus 로고
    • Alzheimer's disease and related dementias: Selective involvement of specific neuronal systems
    • in: J.C. Blass (Ed.), CRC Press, New York
    • P.J. Whitehouse, R.G. Struble, J.C. Hedreen, A.W. Clark, D.L. Price, Alzheimer's disease and related dementias: Selective involvement of specific neuronal systems, in: J.C. Blass (Ed.), Critical Reviews in Clinical Neurobiology, CRC Press, New York, 1985, pp. 319-339.
    • (1985) Critical Reviews in Clinical Neurobiology , pp. 319-339
    • Whitehouse, P.J.1    Struble, R.G.2    Hedreen, J.C.3    Clark, A.W.4    Price, D.L.5


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