Protein-protein docking and analysis reveal that two homologous bacterial adenylyl cyclase toxins interact with calmodulin differently

Journal of Biological Chemistry

Volumn 283, Issue 35, 2008, Pages 23836-23845

  Guo, Qing ^a   Jureller, Justin E ^b   Warren, Julia T ^a,d   Solomaha, Elena ^a   Florián, Jan ^c   Tang, Wei Jen ^a,e  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; ANTIGENS; BACTERIOLOGY; BINDING ENERGY; CALCIUM; CALCIUM ALLOYS; CHEMICAL ACTIVATION; ENERGY TRANSFER; ENZYME ACTIVITY; FETAL MONITORING; FLOW INTERACTIONS; FLUORESCENCE; METABOLITES; MOLECULAR DYNAMICS; ORGANIC ACIDS; PORT TERMINALS;

ADENYLYL CYCLASE; BINDING AFFINITIES; BINDING SURFACES; BIOLOGICAL ACTIVITIES; CALCIUM BINDING MOTIFS; CALCIUM SENSORS; CATALYTIC ACTIVATIONS; DIRECTED MUTATIONS; DISULFIDE BONDS; DO-MAINS; EDEMA FACTORS; ETIOLOGIC AGENTS; EUKARYOTIC CELLS; FLUORESCENCE RESONANCE ENERGY TRANSFERS; GLOBULAR DOMAINS; HELICAL DOMAINS; MOLECULAR DYNAMIC SIMULATIONS; POINT MUTATIONS; PROTEIN DOCKING; SIGNALING PROTEINS; WHOOPING COUGHS; WORKING MODELS;

CAMS;

ADENYLATE CYCLASE; BACTERIAL TOXIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALMODULIN; CYCLIC AMP; ADENYLATE CYCLASE TOXIN; ANTHRAX TOXIN; BACTERIAL ANTIGEN; ENZYME ACTIVATOR;

ARTICLE; BINDING AFFINITY; BORDETELLA PERTUSSIS; CALCIUM BINDING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN MOTIF; SITE DIRECTED MUTAGENESIS; BACILLUS ANTHRACIS; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MISSENSE MUTATION; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SPECIES DIFFERENCE;

BACTERIA (MICROORGANISMS); BORDETELLA PERTUSSIS; EUKARYOTA;

ADENYLATE CYCLASE TOXIN; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; BORDETELLA PERTUSSIS; CALMODULIN; ENZYME ACTIVATORS; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SPECIES SPECIFICITY;

EID: 53049087303     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802168200     Document Type: Article

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