The binding of myristoylated N-terminal nonapeptide from neuron-specific protein CAP-23/NAP-22 to calmodulin does not induce the globular structure observed for the calmodulin-nonmyristoylated peptide complex

Protein Science

Volumn 9, Issue 10, 2000, Pages 1905-1913

  Hayashi, Nobuhiro ^a   Izumi, Yoshinobu ^b   Titani, Koiti ^a   Matsushima, Norio ^c  

^a FUJITA HEALTH UNIVERSITY   (Japan)

^b YAMAGATA UNIVERSITY   (Japan)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

Calmodulin; CAP 23 NAP 22; Myristoylation; Protein protein interaction; Small angle X ray scattering

Indexed keywords

CALCIUM ION; CALMODULIN; NONAPEPTIDE; PROTEIN KINASE C;

AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; ENZYME SUBSTRATE; MYRISTYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RADIATION SCATTERING;

EID: 0033769516     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.9.10.1905     Document Type: Article

References (67)

1. Molecular mechanics of calcium-myristoyl switches
2. Amino-terminal myristoylation induces cooperative calcium binding to recoverin
3. Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: The central helix is flexible
4. The MARCKS family of cellular protein kinase C substrates
5. Characteristics of the F52 protein, a MARCKS homologue
6. Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase
7. A role for N-myristoylation in protein targeting: NADH-cytochrome b5 reductase requires myristic acid for association with outer mitochondrial but not ER membranes
8. Intrinsic neuronal determinants locally regulate extrasynaptic and synaptic growth at the adult neuromuscular junction
9. 2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle
10. Myristylation of picornavirus capsid protein VP4 and its structural significance
11. Drug binding by calmodulin: Crystal structure of a calmodulin-trifluoperazine complex
12. Molecular and structural basis of target recognition by calmodulin
13. NMR solution structure of a complex of calmodulin with a binding peptide of the Ca(2+) pump
14. Recognition and characterization of calmodulin-binding sequences in peptides and proteins
15. Drosophila neurocalcin, a fatty acylated, Ca2+-binding protein that associates with membranes and inhibits in vitro phosphorylation of bovine rhodopsin
16. Modulation of the endothelial nitric-oxide synthase-caveolin interaction in cardiac myocytes
17. Calcium-induced structural changes and domain autonomy in calmodulin
18. Small angle X-ray scattering
19. N-myristoylation of p60src. Identification of a myristoyl-CoA:glycylpeptide N-myristoyltransferase in rat tissues
20. Flagellar protein localization mediated by a calcium-myristoyl/palmitoyl switch mechanism
21. 2O in protein NMR. Application to sensitivity enhancement and NOE measurements
22. La diffraction des rayons X aux tres petits angles; application a l'etude de phenomenes ultramicroscopique
23. HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product
24. The human myristoylated alanine-rich C kinase substrate (MARCKS) gene (MACS)
25. Effect of myristoylation on GTP-dependent binding of ADP-ribosylation factor to Golgi
26. An efficient expression system of rat calmodulin using T7 phage promoter in Escherichia coli
27. Changes in the structure of calmodulin induced by a peptide based on the calmodulin-binding domain of myosin light chain kinase
28. Solution structure of a calmodulin-target peptide complex by multidimensional NMR
29. 15N spectra of larger proteins: Heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin
30. Inhibition of rhodopsin phosphorylation by non-myristoylated recombinant recoverin
31. Phosphorylation reverses the membrane association of peptides that correspond to the basic domains of MARCKS and neuromodulin
32. Regulation of the calmodulin-stimulated protein phosphatase, calcineurin
33. Myristoylation of hippocalcin is linked to its calcium-dependent membrane association properties
34. Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif
35. Crystal structure of calmodulin
36. Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase
37. Purification and molecular cloning of a novel acidic calmodulin binding protein from rat brain
38. Binding of both Ca2+ and mastoparan to calmodulin induces a large change in the tertiary structure
39. The myristoyl-electrostatic switch: A modulator of reversible protein-membrane interactions
40. Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex
41. Modulation of calmodulin plasticity in molecular recognition on the basis of X-ray structures
42. G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells
43. Acetylcholine receptor-associated 43K protein contains covalently bound myristate
44. Calcium binding, but not a calcium-myristoyl switch, controls the ability of guanylyl cyclase-activating protein GCAP-2 to regulate photoreceptor guanylyl cyclase
45. How calmodulin binds its targets: Sequence independent recognition of amphiphilic alpha-helices
46. Evidence for calmodulin inter-domain compaction in solution induced by W-7 binding
47. The central helix of calmodulin functions as a flexible tether
48. Myristylation and palmitylation of Src family members: The fats of the matter
49. Regulation of cellular signaling by fatty acid acylation and prenylation of signal transduction proteins
50. Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae
51. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors
52. Enzymatic characteristics of recombinant medium isozyme of 2'-5' oligoadenylate synthetase
53. Calcium-induced increase in the radius of gyration and maximum dimension of calmodulin measured by small-angle X-ray scattering
54. N-myristoylation of recoverin enhances its efficiency as an inhibitor of rhodopsin kinase
55. Antimyristoylation of gag proteins in human T-cell leukemia and human immunodeficiency viruses with N-myristoyl glycinal diethylacetal
56. Calcium- and myristoyl-dependent subcellular localization of the neuronal calcium-binding protein VILIP in transfected PC12 cells
57. Bending of the calmodulin central helix: A theoretical study
58. Identification of the calmodulin-binding domain of neuron-specific protein kinase C substrate protein CAP-23/NAP-22
59. Interaction of myristoylated alanine-rich protein kinase C substrate (MARCKS) with membrane phospholipids
60. The biology and enzymology of eukaryotic protein acylation
61. Aggregation of bovine serum albumin upon cleavage of its disulfide bonds, studied by the time-resolved small-angle X-ray scattering technique with synchrotron radiation
62. Dual fatty acylation of p59(Fyn) is required for association with the T cell receptor zeta chain through phosphotyrosine-Src homology domain-2 interactions
63. A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: Characterization of a novel gut-specific N-myristoylated annexin
64. Identification, localization, and primary structure of CAP-23, a particle-bound cytosolic protein of early development
65. Ncalcium-calmoduin-induced dimerization of the carboxyl-terminal domain from petunia glutamate decarboxylase
66. Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae
67. Retargeting of cytosolic proteins to the plasma membrane by the Lck protein tyrosine kinase dual acylation motif