-
2
-
-
0032957595
-
Nitric oxide: discovery and impact on clinical medicine
-
Moncada S. Nitric oxide: discovery and impact on clinical medicine. J R Soc Med 92 (1999) 164-169
-
(1999)
J R Soc Med
, vol.92
, pp. 164-169
-
-
Moncada, S.1
-
3
-
-
0028026868
-
Nitric oxide synthase: aspects concerning structure and catalysis
-
Marletta M.A. Nitric oxide synthase: aspects concerning structure and catalysis. Cell 78 (1994) 927-930
-
(1994)
Cell
, vol.78
, pp. 927-930
-
-
Marletta, M.A.1
-
4
-
-
0035425503
-
Nitric oxide synthases: structure, function and inhibition
-
Alderton W.K., Cooper C.E., and Knowles R.G. Nitric oxide synthases: structure, function and inhibition. Biochem J 357 (2001) 593-615
-
(2001)
Biochem J
, vol.357
, pp. 593-615
-
-
Alderton, W.K.1
Cooper, C.E.2
Knowles, R.G.3
-
5
-
-
0041856376
-
alpha-Melanocyte-stimulating hormone inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production in leukocytes by modulating protein kinase A, p38 kinase, and nuclear factor kappa B signaling pathways
-
Yoon S.W., Goh S.H., Chun J.S., Cho E.W., Lee M.K., Kim K.L., et al. alpha-Melanocyte-stimulating hormone inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production in leukocytes by modulating protein kinase A, p38 kinase, and nuclear factor kappa B signaling pathways. J Biol Chem 278 (2003) 32914-32920
-
(2003)
J Biol Chem
, vol.278
, pp. 32914-32920
-
-
Yoon, S.W.1
Goh, S.H.2
Chun, J.S.3
Cho, E.W.4
Lee, M.K.5
Kim, K.L.6
-
6
-
-
0035104119
-
LPS induction of gene expression in human monocytes
-
Guha M., and Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 13 (2001) 85-94
-
(2001)
Cell Signal
, vol.13
, pp. 85-94
-
-
Guha, M.1
Mackman, N.2
-
7
-
-
0034984262
-
Innate immunity and inflammation: a transcriptional paradigm
-
Hawiger J. Innate immunity and inflammation: a transcriptional paradigm. Immunol Res 23 (2001) 99-109
-
(2001)
Immunol Res
, vol.23
, pp. 99-109
-
-
Hawiger, J.1
-
8
-
-
36048973170
-
Localization and activity of iNOS in normal human lung tissue and lung cancer tissue
-
Speranza L., De Lutiis M.A., Shaik Y.B., Felaco M., Patruno A., Tete A., et al. Localization and activity of iNOS in normal human lung tissue and lung cancer tissue. Int J Biol Markers 22 (2007) 226-231
-
(2007)
Int J Biol Markers
, vol.22
, pp. 226-231
-
-
Speranza, L.1
De Lutiis, M.A.2
Shaik, Y.B.3
Felaco, M.4
Patruno, A.5
Tete, A.6
-
9
-
-
39149132505
-
Inducible nitric oxide synthase: correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma
-
Brennan P.A., Dennis S., Poller D., Quintero M., Puxeddu R., and Thomas G.J. Inducible nitric oxide synthase: correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma. Head Neck 30 (2008) 208-214
-
(2008)
Head Neck
, vol.30
, pp. 208-214
-
-
Brennan, P.A.1
Dennis, S.2
Poller, D.3
Quintero, M.4
Puxeddu, R.5
Thomas, G.J.6
-
10
-
-
30744447725
-
A role of p44/42 mitogen-activated protein kinases in formyl-peptide receptor-mediated phospholipase D activity and oxidant production
-
Paruch S., El-Benna J., Djerdjouri B., Marullo S., and Perianin A. A role of p44/42 mitogen-activated protein kinases in formyl-peptide receptor-mediated phospholipase D activity and oxidant production. FASEB J 20 (2006) 142-144
-
(2006)
FASEB J
, vol.20
, pp. 142-144
-
-
Paruch, S.1
El-Benna, J.2
Djerdjouri, B.3
Marullo, S.4
Perianin, A.5
-
11
-
-
0036040714
-
Downregulation of angiotensin converting enzyme by TNF-alpha in differentiating human macrophages
-
Viinikainen A., Nyman T., Fyhrquist F., and Saijonmaa O. Downregulation of angiotensin converting enzyme by TNF-alpha in differentiating human macrophages. Cytokine 18 (2002) 304-310
-
(2002)
Cytokine
, vol.18
, pp. 304-310
-
-
Viinikainen, A.1
Nyman, T.2
Fyhrquist, F.3
Saijonmaa, O.4
-
12
-
-
0037090187
-
Suppression of IL-12 production by soluble CD40 ligand: evidence for involvement of the p44/42 mitogen-activated protein kinase pathway
-
Wittmann M., Kienlin P., Mommert S., Kapp A., and Werfel T. Suppression of IL-12 production by soluble CD40 ligand: evidence for involvement of the p44/42 mitogen-activated protein kinase pathway. J Immunol 168 (2002) 3793-3800
-
(2002)
J Immunol
, vol.168
, pp. 3793-3800
-
-
Wittmann, M.1
Kienlin, P.2
Mommert, S.3
Kapp, A.4
Werfel, T.5
-
13
-
-
34047122615
-
STAT1 and STAT3 phosphorylation by porins are independent of JAKs but are dependent on MAPK pathway and plays a role in U937 cells production of interleukin-6
-
Galdiero M., Vitiello M., D'Isanto M., Raieta K., and Galdiero E. STAT1 and STAT3 phosphorylation by porins are independent of JAKs but are dependent on MAPK pathway and plays a role in U937 cells production of interleukin-6. Cytokine 36 (2006) 218-228
-
(2006)
Cytokine
, vol.36
, pp. 218-228
-
-
Galdiero, M.1
Vitiello, M.2
D'Isanto, M.3
Raieta, K.4
Galdiero, E.5
-
14
-
-
34548396883
-
Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription1/3 pathway
-
Xuan Y.T., Guo Y., Zhu Y., Wang O.L., Rokosh G., and Bolli R. Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription1/3 pathway. Circulation 116 (2007) 535-544
-
(2007)
Circulation
, vol.116
, pp. 535-544
-
-
Xuan, Y.T.1
Guo, Y.2
Zhu, Y.3
Wang, O.L.4
Rokosh, G.5
Bolli, R.6
-
15
-
-
0032999830
-
Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation
-
Dennis P.B., Fumagalli S., and Thomas G. Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation. Curr Opin Genet Dev 9 (1999) 49-54
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 49-54
-
-
Dennis, P.B.1
Fumagalli, S.2
Thomas, G.3
-
16
-
-
2342545519
-
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
-
Fingar D.C., and Blenis J. Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23 (2004) 3151-3171
-
(2004)
Oncogene
, vol.23
, pp. 3151-3171
-
-
Fingar, D.C.1
Blenis, J.2
-
17
-
-
36949017486
-
Regulation of catalytic activity of S6 kinase 2 during cell cycle
-
Boyer D., Quintanilla R., and Lee-Fruman K.K. Regulation of catalytic activity of S6 kinase 2 during cell cycle. Mol Cell Biochem 307 (2008) 59-64
-
(2008)
Mol Cell Biochem
, vol.307
, pp. 59-64
-
-
Boyer, D.1
Quintanilla, R.2
Lee-Fruman, K.K.3
-
18
-
-
0029103330
-
Control of p70 s6 kinase by kinase activity of FRAP in vivo
-
Brown E.J., Beal P.A., Keith C.T., Chen J., Shin T.B., and Schreiber S.L. Control of p70 s6 kinase by kinase activity of FRAP in vivo. Nature 377 (1995) 441-446
-
(1995)
Nature
, vol.377
, pp. 441-446
-
-
Brown, E.J.1
Beal, P.A.2
Keith, C.T.3
Chen, J.4
Shin, T.B.5
Schreiber, S.L.6
-
19
-
-
0034234924
-
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells
-
Sekulic A., Hudson C.C., Homme J.L., Yin P., Otterness D.M., Karnitz L.M., et al. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells. Cancer Res 60 (2000) 3504-3513
-
(2000)
Cancer Res
, vol.60
, pp. 3504-3513
-
-
Sekulic, A.1
Hudson, C.C.2
Homme, J.L.3
Yin, P.4
Otterness, D.M.5
Karnitz, L.M.6
-
20
-
-
0041320828
-
Novel regulatory mechanisms of mTOR signaling
-
Chen J. Novel regulatory mechanisms of mTOR signaling. Curr Top Microbiol Immunol 279 (2004) 245-257
-
(2004)
Curr Top Microbiol Immunol
, vol.279
, pp. 245-257
-
-
Chen, J.1
-
21
-
-
0242496906
-
Phosphatidic acid regulates systemic inflammatory responses by modulating the Akt-mammalian target of rapamycin-p70 S6 kinase 1 pathway
-
Lim H.K., Choi Y.A., Park W., Lee T., Ryu S.H., Kim S.Y., et al. Phosphatidic acid regulates systemic inflammatory responses by modulating the Akt-mammalian target of rapamycin-p70 S6 kinase 1 pathway. J Biol Chem 278 (2003) 45117-45127
-
(2003)
J Biol Chem
, vol.278
, pp. 45117-45127
-
-
Lim, H.K.1
Choi, Y.A.2
Park, W.3
Lee, T.4
Ryu, S.H.5
Kim, S.Y.6
-
22
-
-
33748713337
-
Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-kappaB phosphorylation and nuclear factor-kappaB transcriptional activity through nicotinic acetylcholine receptor alpha7
-
Yoshikawa H., Kurokawa M., Ozaki N., Nara K., Atou K., Takada E., et al. Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-kappaB phosphorylation and nuclear factor-kappaB transcriptional activity through nicotinic acetylcholine receptor alpha7. Clin Exp Immunol 146 (2006) 116-123
-
(2006)
Clin Exp Immunol
, vol.146
, pp. 116-123
-
-
Yoshikawa, H.1
Kurokawa, M.2
Ozaki, N.3
Nara, K.4
Atou, K.5
Takada, E.6
-
23
-
-
36849073794
-
Nicotine inhibits cytokine production by placenta cells via NFkappaB: potential role in pregnancy-induced hypertension
-
Dowling O., Rochelson B., Way K., Al-Abed Y., and Metz C.N. Nicotine inhibits cytokine production by placenta cells via NFkappaB: potential role in pregnancy-induced hypertension. Mol Med 13 (2007) 576-583
-
(2007)
Mol Med
, vol.13
, pp. 576-583
-
-
Dowling, O.1
Rochelson, B.2
Way, K.3
Al-Abed, Y.4
Metz, C.N.5
-
24
-
-
11144355227
-
Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors
-
Shytle R.D., Mori T., Townsend K., Vendrame M., Sun N., Zeng J., et al. Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors. J Neurochem 89 (2004) 337-343
-
(2004)
J Neurochem
, vol.89
, pp. 337-343
-
-
Shytle, R.D.1
Mori, T.2
Townsend, K.3
Vendrame, M.4
Sun, N.5
Zeng, J.6
-
25
-
-
0032501163
-
Nicotine inhibits the production of inflammatory mediators in U937 cells through modulation of nuclear factor-kappaB activation
-
Sugano N., Shimada K., Ito K., and Murai S. Nicotine inhibits the production of inflammatory mediators in U937 cells through modulation of nuclear factor-kappaB activation. Biochem Biophys Res Commun 252 (1998) 25-28
-
(1998)
Biochem Biophys Res Commun
, vol.252
, pp. 25-28
-
-
Sugano, N.1
Shimada, K.2
Ito, K.3
Murai, S.4
-
26
-
-
0021920815
-
Effects of nicotine on the functions of human polymorphonuclear leukocytes in vitro
-
Sasagawa S., Suzuki K., Sakatani T., and Fujikura T. Effects of nicotine on the functions of human polymorphonuclear leukocytes in vitro. J Leukoc Biol 37 (1985) 493-502
-
(1985)
J Leukoc Biol
, vol.37
, pp. 493-502
-
-
Sasagawa, S.1
Suzuki, K.2
Sakatani, T.3
Fujikura, T.4
-
27
-
-
0029440545
-
Inhibition of neutrophil and monocyte defensive functions by nicotine
-
Pabst M.J., Pabst K.M., Collier J.A., Coleman T.C., Lemons-Prince M.L., Godat M.S., et al. Inhibition of neutrophil and monocyte defensive functions by nicotine. J Periodontol 66 (1995) 1047-1055
-
(1995)
J Periodontol
, vol.66
, pp. 1047-1055
-
-
Pabst, M.J.1
Pabst, K.M.2
Collier, J.A.3
Coleman, T.C.4
Lemons-Prince, M.L.5
Godat, M.S.6
-
28
-
-
0030273769
-
Nicotine inhibits the in vitro production of interleukin 2 and tumour necrosis factor-alpha by human mononuclear cells
-
Madretsma G.S., Donze G.J., van Dijk A.P., Tak C.J., Wilson J.H., and Zijlstra F.J. Nicotine inhibits the in vitro production of interleukin 2 and tumour necrosis factor-alpha by human mononuclear cells. Immunopharmacology 35 (1996) 47-51
-
(1996)
Immunopharmacology
, vol.35
, pp. 47-51
-
-
Madretsma, G.S.1
Donze, G.J.2
van Dijk, A.P.3
Tak, C.J.4
Wilson, J.H.5
Zijlstra, F.J.6
-
29
-
-
0029563438
-
Involvement of tyrosine kinases in the induction of cyclo-oxygenase-2 in human endothelial cells
-
Blanco A., Habib A., Levy-Toledano S., and Maclouf J. Involvement of tyrosine kinases in the induction of cyclo-oxygenase-2 in human endothelial cells. Biochem J 312 Pt. 2 (1995) 419-423
-
(1995)
Biochem J
, vol.312
, Issue.PART 2
, pp. 419-423
-
-
Blanco, A.1
Habib, A.2
Levy-Toledano, S.3
Maclouf, J.4
-
30
-
-
0032403566
-
Antisense oligonucleotides targeting protein kinase C-alpha, -beta I, or -delta but not -eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism
-
Chen C.C., Wang J.K., and Lin S.B. Antisense oligonucleotides targeting protein kinase C-alpha, -beta I, or -delta but not -eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism. J Immunol 161 (1998) 6206-6214
-
(1998)
J Immunol
, vol.161
, pp. 6206-6214
-
-
Chen, C.C.1
Wang, J.K.2
Lin, S.B.3
-
31
-
-
0033105530
-
A phosphatidylcholine-specific phospholipase C regulates activation of p42/44 mitogen-activated protein kinases in lipopolysaccharide-stimulated human alveolar macrophages
-
Monick M.M., Carter A.B., Gudmundsson G., Mallampalli R., Powers L.S., and Hunninghake G.W. A phosphatidylcholine-specific phospholipase C regulates activation of p42/44 mitogen-activated protein kinases in lipopolysaccharide-stimulated human alveolar macrophages. J Immunol 162 (1999) 3005-3012
-
(1999)
J Immunol
, vol.162
, pp. 3005-3012
-
-
Monick, M.M.1
Carter, A.B.2
Gudmundsson, G.3
Mallampalli, R.4
Powers, L.S.5
Hunninghake, G.W.6
-
32
-
-
0035013283
-
Phosphatidylcholine-specific phospholipase C and D in stimulation of RAW264.7 mouse macrophage-like cells by lipopolysaccharide
-
Zhang F., Zhao G., and Dong Z. Phosphatidylcholine-specific phospholipase C and D in stimulation of RAW264.7 mouse macrophage-like cells by lipopolysaccharide. Int Immunopharmacol 1 (2001) 1375-1384
-
(2001)
Int Immunopharmacol
, vol.1
, pp. 1375-1384
-
-
Zhang, F.1
Zhao, G.2
Dong, Z.3
-
33
-
-
0034713266
-
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
-
Borovikova L.V., Ivanova S., Zhang M., Yang H., Botchkina G.I., Watkins L.R., et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405 (2000) 458-462
-
(2000)
Nature
, vol.405
, pp. 458-462
-
-
Borovikova, L.V.1
Ivanova, S.2
Zhang, M.3
Yang, H.4
Botchkina, G.I.5
Watkins, L.R.6
-
34
-
-
33847156887
-
Nicotine inhibits bFGF-induced neurite outgrowth through suppression of NO synthesis in H19-7 cells
-
Shin-young P., Koh Y.J., Cho J.H., Oh D.Y., Shin S.A., Lee K.S., et al. Nicotine inhibits bFGF-induced neurite outgrowth through suppression of NO synthesis in H19-7 cells. Neurochem Res 32 (2007) 481-488
-
(2007)
Neurochem Res
, vol.32
, pp. 481-488
-
-
Shin-young, P.1
Koh, Y.J.2
Cho, J.H.3
Oh, D.Y.4
Shin, S.A.5
Lee, K.S.6
-
35
-
-
18144395496
-
Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures
-
De Simone R., Ajmone-Cat M.A., Carnevale D., and Minghetti L. Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures. J Neuroinflammation 2 (2005) 4
-
(2005)
J Neuroinflammation
, vol.2
, pp. 4
-
-
De Simone, R.1
Ajmone-Cat, M.A.2
Carnevale, D.3
Minghetti, L.4
-
36
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L., and Karin M. Mammalian MAP kinase signalling cascades. Nature 410 (2001) 37-40
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
37
-
-
38149083478
-
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway
-
Kim J.H., Kim J.E., Liu H.Y., Cao W., and Chen J. Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway. J Biol Chem 283 (2008) 708-715
-
(2008)
J Biol Chem
, vol.283
, pp. 708-715
-
-
Kim, J.H.1
Kim, J.E.2
Liu, H.Y.3
Cao, W.4
Chen, J.5
-
38
-
-
0036843575
-
Jaks, STATs, cytokines, and sepsis
-
Scott M.J., Godshall C.J., and Cheadle W.G. Jaks, STATs, cytokines, and sepsis. Clin Diagn Lab Immunol 9 (2002) 1153-1159
-
(2002)
Clin Diagn Lab Immunol
, vol.9
, pp. 1153-1159
-
-
Scott, M.J.1
Godshall, C.J.2
Cheadle, W.G.3
-
39
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen Z., Zhong Z., and Darnell Jr. J.E. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82 (1995) 241-250
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr., J.E.3
-
40
-
-
0033968596
-
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR
-
Yokogami K., Wakisaka S., Avruch J., and Reeves S.A. Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR. Curr Biol 10 (2000) 47-50
-
(2000)
Curr Biol
, vol.10
, pp. 47-50
-
-
Yokogami, K.1
Wakisaka, S.2
Avruch, J.3
Reeves, S.A.4
-
41
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer J.S., Silver J.S., Laurence A., Porrett P.M., Harris T.H., Turka L.A., et al. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol 8 (2007) 1363-1371
-
(2007)
Nat Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Harris, T.H.5
Turka, L.A.6
-
42
-
-
23844454674
-
Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway
-
de Jonge W.J., van der Zanden E.P., The F.O., Bijlsma M.F., van Westerloo D.J., Bennink R.J., et al. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nat Immunol 6 (2005) 844-851
-
(2005)
Nat Immunol
, vol.6
, pp. 844-851
-
-
de Jonge, W.J.1
van der Zanden, E.P.2
The, F.O.3
Bijlsma, M.F.4
van Westerloo, D.J.5
Bennink, R.J.6
|