메뉴 건너뛰기




Volumn 22, Issue 10, 2008, Pages 2278-2292

Cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA ARRESTIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; L 779976; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 5; UNCLASSIFIED DRUG;

EID: 52949103344     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2007-0334     Document Type: Article
Times cited : (91)

References (64)
  • 1
    • 0032780823 scopus 로고    scopus 로고
    • Somatostatin and its receptor family
    • Patel YC 1999 Somatostatin and its receptor family. Front Neuroendocrinol 20:157-198
    • (1999) Front Neuroendocrinol , vol.20 , pp. 157-198
    • Patel, Y.C.1
  • 4
    • 29344468043 scopus 로고    scopus 로고
    • Treatment of pituitary tumors: Somatostatin
    • Tichomirowa MA, Daly AF, Beckers A 2005 Treatment of pituitary tumors: somatostatin. Endocrine 28:93-100
    • (2005) Endocrine , vol.28 , pp. 93-100
    • Tichomirowa, M.A.1    Daly, A.F.2    Beckers, A.3
  • 5
    • 15944427116 scopus 로고    scopus 로고
    • The antitumoral effects of somatostatin analog therapy in acromegaly
    • Bevan JS 2005 The antitumoral effects of somatostatin analog therapy in acromegaly. J Clin Endocrinol Metab 90:1856-1863
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1856-1863
    • Bevan, J.S.1
  • 10
    • 0037323565 scopus 로고    scopus 로고
    • The pathophysiological consequences of somatostatin receptor internalization and resistance
    • Hofland LJ, Lamberts SW 2003 The pathophysiological consequences of somatostatin receptor internalization and resistance. Endocr Rev 24:28-47
    • (2003) Endocr Rev , vol.24 , pp. 28-47
    • Hofland, L.J.1    Lamberts, S.W.2
  • 11
    • 17744378733 scopus 로고    scopus 로고
    • Human somatostatin receptor subtypes in acromegaly: Distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes
    • Jaquet P, Saveanu A, Gunz G, Fina F, Zamora AJ, Grino M, Culler MD, Moreau JP, Enjalbert A, Ouafik LH 2000 Human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes. J Clin Endocrinol Metab 85:781-792
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 781-792
    • Jaquet, P.1    Saveanu, A.2    Gunz, G.3    Fina, F.4    Zamora, A.J.5    Grino, M.6    Culler, M.D.7    Moreau, J.P.8    Enjalbert, A.9    Ouafik, L.H.10
  • 12
    • 20844461864 scopus 로고    scopus 로고
    • Somatostatin (SRIF) receptor subtype 2 and 5 gene expression in growth hormone-secreting pituitary adenomas: The relationship with endogenous SRIF activity and response to octreotide
    • Park C, Yang I, Woo J, Kim S, Kim J, Kim Y, Sohn S, Kim E, Lee M, Park H, Jung J, Park S 2004 Somatostatin (SRIF) receptor subtype 2 and 5 gene expression in growth hormone-secreting pituitary adenomas: the relationship with endogenous SRIF activity and response to octreotide. Endocr J 51:227-236
    • (2004) Endocr J , vol.51 , pp. 227-236
    • Park, C.1    Yang, I.2    Woo, J.3    Kim, S.4    Kim, J.5    Kim, Y.6    Sohn, S.7    Kim, E.8    Lee, M.9    Park, H.10    Jung, J.11    Park, S.12
  • 13
    • 34249792384 scopus 로고    scopus 로고
    • Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2
    • Sharif N, Gendron L, Wowchuk J, Sarret P, Mazella J, Beaudet A, Stroh T 2007 Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2. Endocrinology 148:2095-2105
    • (2007) Endocrinology , vol.148 , pp. 2095-2105
    • Sharif, N.1    Gendron, L.2    Wowchuk, J.3    Sarret, P.4    Mazella, J.5    Beaudet, A.6    Stroh, T.7
  • 14
    • 1242276192 scopus 로고    scopus 로고
    • Roles of G-protein-coupled receptor dimerization
    • Terrillon S, Bouvier M 2004 Roles of G-protein-coupled receptor dimerization. EMBO Rep 5:30-34
    • (2004) EMBO Rep , vol.5 , pp. 30-34
    • Terrillon, S.1    Bouvier, M.2
  • 15
    • 23944501304 scopus 로고    scopus 로고
    • Heterodimerization of G protein-coupled receptors: Specificity and functional significance
    • Prinster SC, Hague C, Hall RA 2005 Heterodimerization of G protein-coupled receptors: specificity and functional significance. Pharmacol Rev 57:289-298
    • (2005) Pharmacol Rev , vol.57 , pp. 289-298
    • Prinster, S.C.1    Hague, C.2    Hall, R.A.3
  • 16
    • 0034785580 scopus 로고    scopus 로고
    • Increased AT1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness
    • AbdAlla S, Lother H, el Massiery A, Quitterer U 2001 Increased AT1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness. Nat Med 7:1003-1009
    • (2001) Nat Med , vol.7 , pp. 1003-1009
    • AbdAlla, S.1    Lother, H.2    el Massiery, A.3    Quitterer, U.4
  • 17
    • 7044274535 scopus 로고    scopus 로고
    • Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosis
    • AbdAlla S, Lother H, Langer A, el Faramawy Y, Quitterer U 2004 Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosis. Cell 119:343-354
    • (2004) Cell , vol.119 , pp. 343-354
    • AbdAlla, S.1    Lother, H.2    Langer, A.3    el Faramawy, Y.4    Quitterer, U.5
  • 18
    • 0034677745 scopus 로고    scopus 로고
    • Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers
    • Rocheville M, Lange DC, Kumar U, Sasi R, Patel RC, Patel YC 2000 Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers. J Biol Chem 275:7862-7869
    • (2000) J Biol Chem , vol.275 , pp. 7862-7869
    • Rocheville, M.1    Lange, D.C.2    Kumar, U.3    Sasi, R.4    Patel, R.C.5    Patel, Y.C.6
  • 20
    • 4644253963 scopus 로고    scopus 로고
    • The role of subtype-specific ligand binding and the C-tail domain in dimer formation of human somatostatin receptors
    • Grant M, Patel RC, Kumar U 2004 The role of subtype-specific ligand binding and the C-tail domain in dimer formation of human somatostatin receptors. J Biol Chem 279:38636-38643
    • (2004) J Biol Chem , vol.279 , pp. 38636-38643
    • Grant, M.1    Patel, R.C.2    Kumar, U.3
  • 21
    • 4344571483 scopus 로고    scopus 로고
    • Agonist-dependent dissociation of human somatostatin receptor 2 dimers: A role in receptor trafficking
    • Grant M, Collier B, Kumar U 2004 Agonist-dependent dissociation of human somatostatin receptor 2 dimers: a role in receptor trafficking. J Biol Chem 279:36179-36183
    • (2004) J Biol Chem , vol.279 , pp. 36179-36183
    • Grant, M.1    Collier, B.2    Kumar, U.3
  • 22
    • 0036385623 scopus 로고    scopus 로고
    • Photobleaching fluorescence resonance energy transfer reveals ligand-induced oligomer formation of human somatostatin receptor subtypes
    • Patel RC, Lange DC, Patel YC 2002 Photobleaching fluorescence resonance energy transfer reveals ligand-induced oligomer formation of human somatostatin receptor subtypes. Methods 27:340-348
    • (2002) Methods , vol.27 , pp. 340-348
    • Patel, R.C.1    Lange, D.C.2    Patel, Y.C.3
  • 23
    • 0035252096 scopus 로고    scopus 로고
    • Role of endocytosis in mediating downregulation of G-protein-coupled receptors
    • Tsao P, Cao T, von Zastrow M 2001 Role of endocytosis in mediating downregulation of G-protein-coupled receptors. Trends Pharmacol Sci 22:91-96
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 91-96
    • Tsao, P.1    Cao, T.2    von Zastrow, M.3
  • 24
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by β-arrestins
    • Lefkowitz RJ, Shenoy SK 2005 Transduction of receptor signals by β-arrestins. Science 308:512-517
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 25
    • 2442705543 scopus 로고    scopus 로고
    • Differential β-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes
    • Tulipano G, Stumm R, Pfeiffer M, Kreienkamp HJ, Hollt V, Schulz S 2004 Differential β-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes. J Biol Chem 279:21374-21382
    • (2004) J Biol Chem , vol.279 , pp. 21374-21382
    • Tulipano, G.1    Stumm, R.2    Pfeiffer, M.3    Kreienkamp, H.J.4    Hollt, V.5    Schulz, S.6
  • 27
    • 33646386694 scopus 로고    scopus 로고
    • Airway smooth muscle prostaglandin-EP1 receptors directly modulate β2-adrenergic receptors within a unique heterodimeric complex
    • McGraw DW, Mihlbachler KA, Schwarb MR, Rahman FF, Small KM, Almoosa KF, Liggett SB 2006 Airway smooth muscle prostaglandin-EP1 receptors directly modulate β2-adrenergic receptors within a unique heterodimeric complex. J Clin Invest 116:1400-1409
    • (2006) J Clin Invest , vol.116 , pp. 1400-1409
    • McGraw, D.W.1    Mihlbachler, K.A.2    Schwarb, M.R.3    Rahman, F.F.4    Small, K.M.5    Almoosa, K.F.6    Liggett, S.B.7
  • 30
    • 0141925804 scopus 로고    scopus 로고
    • sst2 somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation
    • Lahlou H, Saint-Laurent N, Esteve JP, Eychene A, Pradayrol L, Pyronnet S, Susini C 2003 sst2 somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation. J Biol Chem 278:39356-39371
    • (2003) J Biol Chem , vol.278 , pp. 39356-39371
    • Lahlou, H.1    Saint-Laurent, N.2    Esteve, J.P.3    Eychene, A.4    Pradayrol, L.5    Pyronnet, S.6    Susini, C.7
  • 34
    • 0141676019 scopus 로고    scopus 로고
    • Functional association of somatostatin receptor subtypes 2 and 5 in inhibiting human growth hormone secretion
    • Ren SG, Taylor J, Dong J, Yu R, Culler MD, Melmed S 2003 Functional association of somatostatin receptor subtypes 2 and 5 in inhibiting human growth hormone secretion. J Clin Endocrinol Metab 88:4239-4245
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4239-4245
    • Ren, S.G.1    Taylor, J.2    Dong, J.3    Yu, R.4    Culler, M.D.5    Melmed, S.6
  • 39
    • 0037125187 scopus 로고    scopus 로고
    • Agonist-promoted heteromeric oligomerization between adenosine A1 and P2Y1 receptors in living cells
    • Yoshioka K, Saitoh O, Nakata H 2002 Agonist-promoted heteromeric oligomerization between adenosine A1 and P2Y1 receptors in living cells. FEBS Lett 523:147-151
    • (2002) FEBS Lett , vol.523 , pp. 147-151
    • Yoshioka, K.1    Saitoh, O.2    Nakata, H.3
  • 41
    • 17844410926 scopus 로고    scopus 로고
    • Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: A mechanism for receptor cross-talk?
    • Kearn CS, Blake-Palmer K, Daniel E, Mackie K, Glass M 2005 Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? Mol Pharmacol 67:1697-1704
    • (2005) Mol Pharmacol , vol.67 , pp. 1697-1704
    • Kearn, C.S.1    Blake-Palmer, K.2    Daniel, E.3    Mackie, K.4    Glass, M.5
  • 42
    • 33746583963 scopus 로고    scopus 로고
    • Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers
    • Jiang H, Betancourt L, Smith RG 2006 Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers. Mol Endocrinol 20:1772-1785
    • (2006) Mol Endocrinol , vol.20 , pp. 1772-1785
    • Jiang, H.1    Betancourt, L.2    Smith, R.G.3
  • 43
    • 0032516914 scopus 로고    scopus 로고
    • The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization
    • Hukovic N, Panetta R, Kumar U, Rocheville M, Patel YC 1998 The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization. J Biol Chem 273:21416-21422
    • (1998) J Biol Chem , vol.273 , pp. 21416-21422
    • Hukovic, N.1    Panetta, R.2    Kumar, U.3    Rocheville, M.4    Patel, Y.C.5
  • 44
    • 0033609946 scopus 로고    scopus 로고
    • Agonist-dependent up-regulation of human somatostatin receptor type 1 requires molecular signals in the cytoplasmic C-tail
    • Hukovic N, Rocheville M, Kumar U, Sasi R, Khare S, Patel YC 1999 Agonist-dependent up-regulation of human somatostatin receptor type 1 requires molecular signals in the cytoplasmic C-tail. J Biol Chem 274:24550-24558
    • (1999) J Biol Chem , vol.274 , pp. 24550-24558
    • Hukovic, N.1    Rocheville, M.2    Kumar, U.3    Sasi, R.4    Khare, S.5    Patel, Y.C.6
  • 45
    • 85047685740 scopus 로고    scopus 로고
    • Intracellular dynamics of sst5 receptors in transfected COS-7 cells: Maintenance of cell surface receptors during ligand-induced endocytosis
    • Stroh T, Jackson AC, Sarret P, Dal Farra C, Vincent JP, Kreienkamp HJ, Mazella J, Beaudet A 2000 Intracellular dynamics of sst5 receptors in transfected COS-7 cells: maintenance of cell surface receptors during ligand-induced endocytosis. Endocrinology 141:354-365
    • (2000) Endocrinology , vol.141 , pp. 354-365
    • Stroh, T.1    Jackson, A.C.2    Sarret, P.3    Dal Farra, C.4    Vincent, J.P.5    Kreienkamp, H.J.6    Mazella, J.7    Beaudet, A.8
  • 46
    • 1242274647 scopus 로고    scopus 로고
    • Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with β-arrestin and their trafficking patterns
    • Terrillon S, Barberis C, Bouvier M 2004 Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with β-arrestin and their trafficking patterns. Proc Natl Acad Sci USA 101:1548-1553
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1548-1553
    • Terrillon, S.1    Barberis, C.2    Bouvier, M.3
  • 47
    • 33846031539 scopus 로고    scopus 로고
    • NTS2 modulates the intracellular distribution and trafficking of NTS1 via heterodimerization
    • Perron A, Sharif N, Sarret P, Stroh T, Beaudet A 2007 NTS2 modulates the intracellular distribution and trafficking of NTS1 via heterodimerization. Biochem Biophys Res Commun 353:582-590
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 582-590
    • Perron, A.1    Sharif, N.2    Sarret, P.3    Stroh, T.4    Beaudet, A.5
  • 49
    • 0029894515 scopus 로고    scopus 로고
    • Transforming growth factor-β and p27 expression in pituitary cells
    • Qian X, Jin L, Grande JP, Lloyd RV 1996 Transforming growth factor-β and p27 expression in pituitary cells. Endocrinology 137:3051-3060
    • (1996) Endocrinology , vol.137 , pp. 3051-3060
    • Qian, X.1    Jin, L.2    Grande, J.P.3    Lloyd, R.V.4
  • 50
    • 0031737719 scopus 로고    scopus 로고
    • DNA methylation regulates p27kip1 expression in rodent pituitary cell lines
    • Qian X, Jin L, Kulig E, Lloyd RV 1998 DNA methylation regulates p27kip1 expression in rodent pituitary cell lines. Am J Pathol 153:1475-1482
    • (1998) Am J Pathol , vol.153 , pp. 1475-1482
    • Qian, X.1    Jin, L.2    Kulig, E.3    Lloyd, R.V.4
  • 51
    • 0031809905 scopus 로고    scopus 로고
    • Mutation and expression analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in pituitary tumors
    • Takeuchi S, Koeffler HP, Hinton DR, Miyoshi I, Melmed S, Shimon I 1998 Mutation and expression analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in pituitary tumors. J Endocrinol 157:337-341
    • (1998) J Endocrinol , vol.157 , pp. 337-341
    • Takeuchi, S.1    Koeffler, H.P.2    Hinton, D.R.3    Miyoshi, I.4    Melmed, S.5    Shimon, I.6
  • 55
    • 0034616021 scopus 로고    scopus 로고
    • Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
    • Rocheville M, Lange DC, Kumar U, Patel SC, Patel RC, Patel YC 2000 Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science 288:154-157
    • (2000) Science , vol.288 , pp. 154-157
    • Rocheville, M.1    Lange, D.C.2    Kumar, U.3    Patel, S.C.4    Patel, R.C.5    Patel, Y.C.6
  • 56
    • 0034618268 scopus 로고    scopus 로고
    • AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration
    • AbdAlla S, Lother H, Quitterer U 2000 AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. Nature 407:94-98
    • (2000) Nature , vol.407 , pp. 94-98
    • AbdAlla, S.1    Lother, H.2    Quitterer, U.3
  • 58
    • 0035912846 scopus 로고    scopus 로고
    • Heteromeric association creates a P2Y-like adenosine receptor
    • Yoshioka K, Saitoh O, Nakata H 2001 Heteromeric association creates a P2Y-like adenosine receptor. Proc Natl Acad Sci USA 98:7617-7622
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7617-7622
    • Yoshioka, K.1    Saitoh, O.2    Nakata, H.3
  • 63
    • 15744401602 scopus 로고    scopus 로고
    • Heterodimerization of μ-and δ-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions
    • Law PY, Erickson-Herbrandson LJ, Zha QQ, Solberg J, Chu J, Sarre A, Loh HH 2005 Heterodimerization of μ-and δ-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions. J Biol Chem 280:11152-11164
    • (2005) J Biol Chem , vol.280 , pp. 11152-11164
    • Law, P.Y.1    Erickson-Herbrandson, L.J.2    Zha, Q.Q.3    Solberg, J.4    Chu, J.5    Sarre, A.6    Loh, H.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.