Coxsackievirus experimental heart diseases

Frontiers in Bioscience

Volumn 8, Issue , 2003, Pages

  Gauntt, Charles ^a,c   Huber, Sally ^b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF VERMONT   (United States)

^c Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Animal Models; Autoimmunity; Coxsackieviruses; Cytokines; Myocarditis; Persistent Viral RNA; Polymerase Chain Reaction; Review

Indexed keywords

CYCLOSPORIN A; INTERFERON;

AUTOIMMUNITY; COXSACKIE VIRUS; COXSACKIE VIRUS B3; CYTOKINE RELEASE; HUMAN; IMMUNE RESPONSE; MORBIDITY; REVIEW; STRAIN DIFFERENCE; VIRUS MYOCARDITIS;

ANIMALIA; COXSACKIEVIRUS; MURINAE;

EID: 3142765526     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: None     Document Type: Review

References (81)

1. Christian, H.A.: Nearly ten decades of interest in idiopathic pericarditis. Am Heart J 42, 645-649 (1951)
2. Huber, S.A., C.J. Gauntt, and P. Sakkinen: Enteroviruses and myocarditis: Viral pathogenesis through replication, cytokine induction and immunopathogenicity. Adv Virus Res 51, 35-80 (1998)
3. Friman, G., and J. Fohlman: Infectious myocarditis and dilated cardiomyopathy. Curr Opin Infect Dis 10, 202-208 (1997)
4. Kawai, C.: From myocarditis to cardiomyopathy: mechanisms of inflammation and cell death: learning from the past for the future. Circulation 99, 1091-1100 (1999)
5. Towbin, J.A.: Myocarditis and pericarditis in adolescents. Adoles Med: state of the art reviews 12, 47-67 (2001)
6. Kim, K.-S., K. Hofling, S.D. Carson, N.M. Chapman, and S. Tracy: The Primary Viruses of Myocarditis. In Myocarditis Eds. Cooper, L.T. and Knowlton, K, Mayo Academic Press, Rochester, MN (In Press) (2002)
7. Bowles, N.E., and J.A. Towbin: Molecular aspects of myocarditis. Curr Inf Dis Reports 2, 308-314 (2000)
8. Hufnagel, G., S. Pankuweit, A. Richter, U. Schonian and B. Maisch: The European Study of Epidemiology and Treatment of Cardiac Inflammatory Diseases (ESETCID). First epidemiological results. Herz 25, 279-285 (2000)
9. Matsumori, A., N. Ohashi, K. Hasegawa, S. Sasayama, T. Eto, T. Imaizumi, T. Izumi: Hepatitis C virus infection and heart diseases: a multicenter study in Japan. Jpn Circ J 62, 389-391 (1998)
10. Wynn, J., and E. Branwald: The Cardiomyopathies and Mycarditides. In: Heart Disease: A Textbook of Cardiovascular Medicine. Ed. Branwald, E, W.B. Saunders, Philadelphia, PA. (1997)
11. Mason, J.W., J.B. O'Connell, A. Herskowitz, N.R. Rose, B.M. McManus, M.E. Billingham, T.E. Moon, and the Myocarditis Treatment Trial Investigators: A clinical trial of immunosuppressive therapy for myocarditis. N Eng J Med 333, 269-313 (1995)
12. Woodruff, J.F.: Viral myocarditis. A review. Am J Pathol 101, 425-483 (1980)
13. Leslie, K., R. Blay, C. Haisch, P. Lodge, A. Weller, and S. Huber: Clinical and experimental aspects of viral myocarditis. Clin Microbiol Rev 2, 191-203 (1989)
14. Modlin, J.F., and H.A. Rotbart: Group B coxsackie disease in children. Curr Top Microbiol Immunol 223, 53-80 (1997)
15. Gauntt, C.J., P. Sakkinen, N.R. Rose, and S.A. Huber: Picornaviruses: immunopathology and autoimmunity. In: Effects of Microbes on the Immune System, Eds. Cunningham, M.W., Fujinami, R.S., Lippincott-Raven Publishers, Philadelphia, PA. 313-329 (1999)
16. Kim, K.-S., G. Hufnagel, N.M. Chapman, and S. Tracy: The group B coxsackieviruses and myocarditis. Rev Med Virol (In Press) (2002)
17. Gauntt, C.J.: Roles of the humoral response in coxsackievirus B-induced disease. Curr Top Microbiol Immunol 223, 259-282 (1997)
18. Gauntt, C.J.: Introduction and historical perspective on experimental myocarditis. In: Myocarditis, Eds. Cooper, L.T., Knowlton, K., Mayo Academic Press, Rochester, MN, 1-22 (2002)
19. Kogon, A., I. Spigland, T.E. Frothingham, L. Elveback, C. Williams, C.E. Hall, and J.P. Fox: The virus watch program: A continuing surveillance of viral infections in metropolitan New York families. VII. Observation on viral excretion, seroimmunity, intrafamilial spread and illness association in coxsackie and echovirus infections. Am J Epidem 89, 51-61 (1969)
20. Grist, N.R., E.J. Bell, and F. Assaad: Enteroviruses in human disease. Prog Med Virol 24, 114-157 (1978)
21. Lau, R.C.H.: Coxsackie B virus infection in New Zealand patients with cardiac and non-cardiac diseases. J Med Virol 11, 131-137 (183)
22. Roggendorf, M.: Experience with enzyme-linked immunosorbent assay for the detection of antibodies of the IgM class against coxsackie B viruses. In: Viral Heart Disease. Ed. Bolte, H., Springer, Berlin, 116-123 (1984)
23. Lerner, A.M., and M.P. Reyes: Coxsackievirus myocarditis-with special reference to acute and chronic effects. Prog Cardiovasc Dis 27, 373-394 (1985)
24. Martino, T., P. Liu, M. Petric, and M.J. Sole: Enteroviral myocarditis and dilated cardiomyopathy: a review of clinical and experimental studies. In: Human Enterovirus Infections. Ed. Rotbart, H.A., Amer. Soc. Microbiol., Washington, D.C., 291-351 (1995)
25. Rose, N.R., D.A. Neumann, and A. Herskowitz: Coxsackievirus myocarditis. Adv Internal Med 37, 411-429 (1992)
26. van Regenmortel, M.H.V., C.M. Fauquet, D.H.L. Bishop, E.B. Carstens, M.K. Estes, S.M. Lemon, J. Maniloff, M.A. Mayo, D.J. McGeoch, C.R. Pringle, and R.B. Wickner. Virus Taxonomy: The Classification and Nomenclature of Viruses. The Seventh Report of the International Committee on Taxonomy of Viruses. Virus Taxonomy, VIIth report of the ICTV. Academic Press, San Diego, p. 657-678. (2000)
27. Bergelson, J.M., J.F. Modlin, W. Wieland-Alter, J.A. Cunningham, R.L. Crowell, and R.W. Finberg: Clinical coxsackievirus B isolates differ from laboratory strains in their interaction with two cell surface receptors J Infect Dis 175, 697-700 (1997)
28. Melnick, J.L.: Picornavirus group Virology 19, 114-116 (163)
29. Crowell, R.L., and B.J. Landau: A short history and introductory background on the coxsackieviruses of group B. Curr Top Microbiol Immunol 223, 1-11 (1997)
30. Baboonian, C., and T. Treasure: Meta-analysis of the association of enteroviruses with human heart disease. Heart 78, 539-543 (1997)
31. Abelmann, W.H.: Virus and the heart. Circulation 44, 950-956 (1971)
32. Fairweather, D., Z. Kaya, G.R. Shellam, C.M. Lawson, and N.R. Rose: From infection to autoimmunity. J Autoimmun 16, 175-186 (2001)
33. Gauntt, C., A. Higdon, D. Bowers, E. Maull, J. Wood, and R. Crawley: What lessons can be learned from animal models studies in viral heart diseases? Scand J Infect Dis 88(Suppl), 49-65 (1993)
34. Gauntt, C.J., E.K. Godeny, and C.W. Lutton: Host factors regulating viral clearance. Pathol Immunopathol Res 7, 251-265 (1988)
35. Huber, S.: Coxsackievirus-induced myocarditis is dependent on distinct immunopathogenic responses in different strains of mice. Lab Invest 76, 691-701 (1997)
36. Huber, S.A., A. Weller, H. Herzum, P.A. Lodge, M. Estrin, K. Simpson, and M. Guthrie: Immunopathogenic mechanisms in experimental picornavirus-induced autoimmunity. Pathol Immunopathol Res 7, 279-291 (1988)
37. Gauntt, C.J., R. Montellano, and T.A. Skogg: Links between viral infections and heart disease. In: Proceedings of the International Congress on Cardiomyopathies and Heart Failure. Ed. Matsumori A., Kyoto, Japan, May 30-June 1, Kluwer Academic Publishers (In Press) (2002)
38. Liu, P.: The role of cytokines in the pathogenesis. In: The Role of Immune Mechanisms in Cardiovascular Disease. Eds. Schultheiss, H.-P., Schwimmbeck, P., 44-56 (1997)
39. Hiscott, J., H. Kwon, and P. Genin: Hostile takeovers: viral appropriation of the NFkappaB pathway. J Clin Invest 107, 143-151 (2001)
40. Lyden, D., J. Olszewski, and S. Huber: Variation in susceptibility of BALB/c mice to coxsackievirus group B type 3-induced myocarditis with age. Cell Immunol 105, 332-339 (1987)
41. 2 cell responses in male and female BALB/c mice infected with coxsackievirus group B type 3. J Virol 68, 5126-5132 (1994)
42. Martino, T.A., M. Petric, K. Aitken, C.J. Gauntt, L. Chow, and P. Liu: Cardiovirulent coxsackieviruses and the decay-accelerating factor (CD55) receptor. Virology 244, 302-314 (1998)
43. Martino, T.A., M. Petric, H. Weingartl, J.M. Bergelson, M.A. Opansky, C.D. Richardson, J.F. Modlin, R.W. Finberg, K. Kain, N. Willis, C.J. Gauntt, and P.P. Liu: The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B, and by swine vesicular disease virus. Virology 271, 99-108 (2000)
44. Tosello, A., F. Mary, M. Amiot, A. Bernard, and D. Mary: Activation of T cells via CD55: recruitment of early components of the CD3-TCR pathway is required for IL-2 secretion. J Inflamm 48, 13-27 (1998)
45. lck is essential in coxsackievirus B3-mediated heart disease. Nat Med 6, 429-434 (2000)
46. Lowenstein, C.J., S.L. Hill, A. Lafond-Walker, J. Wu, G. Allen, M. Landavere, and N.R. Rose: Nitric oxide inhibits viral replication in murine myocarditis. J Clin Invest 97, 1837-1843 (1996)
47. + T-cell responses in coxsackievirus B3-induced myocarditis in mice. J Virol 73, 4689-4695 (1999)
48. Huber, S.: T cells expressing the gamma/delta T cell receptor regulate susceptibility in myocarditis and atherosclerosis. Curr Med 2, 189-191 (1999)
49. + T cells promote susceptibility to coxsackievirus B3-induced myocarditis in mice. J Immunol 165, 4174-4181 (2000)
50. Beck, M.A., and O.A. Levander: Effects of nutritional antioxidants and other dietary constituents on coxsackievirus-induced myocarditis. Curr Top Microbiol Immunol 223, 81-96 (1997)
51. Huber, S.A., and P.A. Lodge: Coxsackievirus B3 myocarditis: identification of different mechanisms in DBA/2 and Balb/c mice. Am J Pathol 122, 284-291 (1986)
52. Liao, L.: Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity. J Exp Med 187, 1123-1130 (1995)
53. + cytolytic lymphocytes. Cell Immunol 88, 558-567 (1984)
54. Schwimmbeck, P.L., S.A. Huber, and H.-P. Schultheiss: Roles of T cells in coxsackievirus B-induced disease. Curr Top Microbiol Immunol 223, 283-303 (1997)
55. + T cell receptor. J Virol 70, 3039-3045 (1996)
56. + T cells regulate major histocompatibility complex class II (IA and IE)-dependent susceptibility to coxsackievirus Be-induced autoimmune myocarditis. J Virol 73, 5630-5636 (1999)
57. Neumann, D.A., J.R. Lane, G.S. Allen, A. Herskowitz, and N.R. Rose: Viral myocarditis leading to cardiomyopathy: Do cytokines contribute to pathogenesis? Clin Immunol Immunopathol 68, 181-190 (1993)
58. Seko, Y., N. Takahashi, H. Yagita, K. Okumura, and Y. Yazaki: Expression of cytokine mRNAs in murine hearts with acute myocarditis caused by coxsackievirus b3. J Pathol 183, 105-108 (1997)
59. Freeman, G., J. Colston, M. Zabalgoitia, and B. Chandrasekar: Contractile depression and expression of proinflammatory cytokines and iNOS in viral myocarditis. Am J Physiol 274, H249-H258 (1998)
60. Henke, A., C. Mohr, H. Sprenger, C. Graebner, A. Stelzner, M. Nain, and D. Gemsa: Coxsackievirus B3-induced production of tumor necrosis factor-alpha, IL-1beta, and IL-6 in human monocytes. J Immunol 148, 2270-2277 (1992)
61. Heim, A., S. Zeuke, S. Weiss, W. Ruschewski, and I.M. Grumbach: Transient induction of cytokine production in human myocardial fibroblasts by coxsackievirus B3. Circ Res 86, 753-759 (2000)
62. Matsumori, A., T. Yamada, H. Suzuki, Y. Matoba, and S. Sasayama: Increased circulating cytokines in patients with myocarditis and cardiomyopathy. Br Heart J 72, 561-566 (1994)
63. Satoh, M., G. Tamura, I. Segawa, A. Tashiro, K. Hiramori, and R. Satodate: Expression of cytokine genes and presence of enteroviral genomic RNA in endomyocardial biopsy tissues of myocarditis and dilated cardiomyopathy. Virchows Arch 427, 503-509 (1996)
64. Huber, S.A., J. Polgar, P. Schultheiss, and P. Schwimmbeck: Augmentation of pathogenesis of coxsackievirus B3 infections in mice by exogenous administration of interleukin-1 and interleukin-2. J Virol 68, 195-206 (1994)
65. Lane, J.R., D.A. Neumann, A. Lafond-Walker, A. Kerskowitz, and N.R. Rose: Role of IL-1 and tumor necrosis factor in coxsackievirus-induced autoimmune myocarditis. J Immunol 151, 1682-1690 (1993)
66. Seko, Y., H. Matsuda, K. Kato, Y. Hashimoto, H. Yagita, K. Okumura, and Y. Yazaki: Expression of intercellular adhesion molecule-1 in murine hearts with acute myocarditis caused by coxsackievirus B3. J Clin Invest 91, 1327-1336 (1993)
67. +-Th-cell phenotype and susceptibility of BALB/c mice to coxsackievirus B3-induced myocarditis. J Virol 75, 5860-5869 (2001)
68. Maisch, B., L. Drude, C. Hengstenberg, M. Herzum, G. Hufnagel, K. Kochsiek, A. Schmaltz, U. Schonian, and M.D. Schwab: Are antisarcolemmal (ASAs) and antimyolemmal antibodies (AMLAs) "natural" antibodies. Basic Res Cardiol 86(Suppl 3), 101-114 (1991)
69. Pankuweit, S., I. Portig, F. Lottspeich, and B. Maisch: Autoantibodies in sera of patients with myocarditis: characterization of the corresponding antigens by isoelectric focusing and n-terminal sequence analysis. J Mol Cell Cardiol 29, 77-84 (1997)
70. Schultheiss, H.-P.: The significance of auto-antibodies against the ADP/ATP carrier for the pathogenesis of myocarditis and dilated cardiomyopathy: clinical and experimental data. Springer Sem Immunopathol 11, 15-30 (1989)
71. Maisch, B., E. Bauer, M. Cirsi, and K. Kocksiek: Cytolytic cross-reactive antibodies directed against the cardiac membrane and viral proteins in coxsackievirus B3 and B4 myocarditis. Circulation 87(Suppl IV), 49-65 (1993)
72. Schwimmbeck, P.L., N.K. Schwimmbeck, H.-P. Schultheiss, and B.E. Strauer: Mapping of antigenic determinants of the adenine-nucleotide translocator and coxsackie B3 virus with synthetic peptides: Use for the diagnosis of viral heart disease. Clin Immunol Immunopathol 68, 135-140 (1993)
73. Huber, S.A., and C.J. Gauntt: Antigenic mimicry between self and coxsackievirus proteins leads to both humoral and cellular autoimmunity to heart proteins. In: Molecular Mimicry, Microbes and Autoimmunity. Eds. Cunningham, M.W., Fujinami, R.S., ASM Press, East Norwalk, CT. 57-68. (1999)
74. Neumann, D.A., N.R. Rose, A.A. Ansari, and A. Herskowitz: Induction of multiple heart autoantibodies in mice with coxsackievirus B3- and cardiac myosin-induced autoimmune myocarditis. J Immunol 152, 43-350 (1994)
75. Neumann, D.A., C.L. Burek, K.L. Baughman, N.R. Rose, and A. Herskowitz: Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy. J Am Col Cardiol 16, 839-846 (1990)
76. Huber, S.: Animal models of human disease - autoimmunity in myocarditis: relevance of animal models. Clin Immunol Immunopathol 83, 93-102 (1997)
77. Cunningham, M.W., S.M. Antone, J.M. Gulizia, B.M. McManus, V.A. Fishetti, and C.J. Gauntt: Cytotoxic and viral neutralizing antibodies crossreact with streptococcal M protein, enteroviruses and human cardiac myosin. Proc Natl Acad Sci USA 89, 1320-1324 (1992)
78. Kandolf, R.: The impact of recombinant DNA technology on the study of enterovirus heart disease. In: Coxsackieviruses. A General Update. Eds. Bendinelli, M., Friedman, H., Plenum Press, New York. 293-318 (1988)
79. Tracy, S., V. Wiegand, B. McManus, C. Gauntt, M. Pallansch, M. Beck, and N. Chapman: Molecular approaches to enteroviral diagnosis in idiopathic cardiomyopathy and myocarditis. J Am Coll Cardiol 15, 1688-1694 (1990)
80. Klingel, K., and R. Kandolf: The role of enterovirus replication in the development of acute and chronic heart muscle disease in different immunocompetent mouse strains. Scand J Infect Dis 88(Suppl), 79-85 (1993)
81. Herzum, M., and S.A. Huber: Treatment of experimental murine Coxsackie B3 myocarditis. Eur Heart J 12 Suppl D, 200-203 (1991)