-
1
-
-
0000197284
-
Pancreatic extracts in the treatment of diabetes mellitus: Preliminary report
-
Banting FG, Best CH, Collip JB et al. Pancreatic extracts in the treatment of diabetes mellitus: Preliminary report. Can Med Assoc J 1922: 12: 141-146.
-
(1922)
Can Med Assoc J
, vol.12
, pp. 141-146
-
-
Banting, F.G.1
Best, C.H.2
Collip, J.B.3
-
2
-
-
0348047628
-
Gene regulatory factors in pancreatic development
-
Jensen J. Gene regulatory factors in pancreatic development. Dev Dyn 2004: 229: 176-200.
-
(2004)
Dev Dyn
, vol.229
, pp. 176-200
-
-
Jensen, J.1
-
3
-
-
33847402673
-
Pancreas and beta-cell development: From the actual to the possible
-
Murtaugh LC. Pancreas and beta-cell development: From the actual to the possible. Development 2007: 134: 427-438.
-
(2007)
Development
, vol.134
, pp. 427-438
-
-
Murtaugh, L.C.1
-
5
-
-
0033853143
-
Development of the pancreas in Xenopus laevis
-
Kelly OG, Melton DA. Development of the pancreas in Xenopus laevis. Dev Dyn 2000: 218: 615-627.
-
(2000)
Dev Dyn
, vol.218
, pp. 615-627
-
-
Kelly, O.G.1
Melton, D.A.2
-
6
-
-
35349020015
-
An illustrated review of early pancreas development in the mouse
-
Jorgensen MC, Ahnfelt-Ronne J, Hald J et al. An illustrated review of early pancreas development in the mouse. Endocr Rev 2007: 28: 685-705.
-
(2007)
Endocr Rev
, vol.28
, pp. 685-705
-
-
Jorgensen, M.C.1
Ahnfelt-Ronne, J.2
Hald, J.3
-
7
-
-
0037213654
-
From endoderm formation to liver and pancreas development in zebrafish
-
Ober EA, Field HA, Stainier DY. From endoderm formation to liver and pancreas development in zebrafish. MechDev 2003: 120: 5-18.
-
(2003)
MechDev
, vol.120
, pp. 5-18
-
-
Ober, E.A.1
Field, H.A.2
Stainier, D.Y.3
-
8
-
-
16544378027
-
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas
-
Lin JW, Biankin AV, Horb ME et al. Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas. Dev Biol 2004: 274: 491-503.
-
(2004)
Dev Biol
, vol.274
, pp. 491-503
-
-
Lin, J.W.1
Biankin, A.V.2
Horb, M.E.3
-
9
-
-
34047181476
-
Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas
-
Jarikji ZH, Vanamala S, Beck CW et al. Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas. Dev Biol 2007: 304: 786-799.
-
(2007)
Dev Biol
, vol.304
, pp. 786-799
-
-
Jarikji, Z.H.1
Vanamala, S.2
Beck, C.W.3
-
10
-
-
0037458120
-
Experimental conversion of liver to pancreas
-
Horb ME, Shen CN, Tosh D et al. Experimental conversion of liver to pancreas. Curr Biol 2003: 13: 105-115.
-
(2003)
Curr Biol
, vol.13
, pp. 105-115
-
-
Horb, M.E.1
Shen, C.N.2
Tosh, D.3
-
11
-
-
0041508755
-
Formation of the digestive system in zebrafish. II. Pancreas morphogenesis
-
Field HA, Dong PD, Beis D et al. Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Dev Biol 2003: 261: 197-208.
-
(2003)
Dev Biol
, vol.261
, pp. 197-208
-
-
Field, H.A.1
Dong, P.D.2
Beis, D.3
-
12
-
-
33644746214
-
Germ layers to organs: Using Xenopus to study "later"development
-
Blitz IL, Andelfinger G, Horb ME. Germ layers to organs: Using Xenopus to study "later"development. SeminCell Dev Biol 2006: 17: 133-145.
-
(2006)
SeminCell Dev Biol
, vol.17
, pp. 133-145
-
-
Blitz, I.L.1
Andelfinger, G.2
Horb, M.E.3
-
13
-
-
33744814639
-
Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue
-
Afelik S, Chen Y, Pieler T. Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. Genes Dev 2006: 20: 1441-1446.
-
(2006)
Genes Dev
, vol.20
, pp. 1441-1446
-
-
Afelik, S.1
Chen, Y.2
Pieler, T.3
-
14
-
-
0024471574
-
XlHbox 8: A novel Xenopus homeo protein restricted to a narrow band of endoderm
-
Wright CV, Schnegelsberg P, De Robertis EM. XlHbox 8: A novel Xenopus homeo protein restricted to a narrow band of endoderm. Development 1989: 105: 787-794.
-
(1989)
Development
, vol.105
, pp. 787-794
-
-
Wright, C.V.1
Schnegelsberg, P.2
De Robertis, E.M.3
-
15
-
-
0027373441
-
Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
-
Leonard J, Peers B, Johnson T et al. Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol 1993: 7: 1275-1283.
-
(1993)
Mol Endocrinol
, vol.7
, pp. 1275-1283
-
-
Leonard, J.1
Peers, B.2
Johnson, T.3
-
16
-
-
0027384997
-
IPF1, a homeodomain-containing transactivator of the insulin gene
-
Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 1993: 12: 4251-4259.
-
(1993)
EMBO J
, vol.12
, pp. 4251-4259
-
-
Ohlsson, H.1
Karlsson, K.2
Edlund, T.3
-
17
-
-
0028314969
-
IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
-
Miller CP, McGehee RE Jr, Habener JF. IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J 1994: 13: 1145-1156.
-
(1994)
EMBO J
, vol.13
, pp. 1145-1156
-
-
Miller, C.P.1
McGehee Jr., R.E.2
Habener, J.F.3
-
18
-
-
0028206319
-
XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor
-
Peshavaria M, Gamer L, Henderson E et al. XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol Endocrinol 1994: 8: 806-816.
-
(1994)
Mol Endocrinol
, vol.8
, pp. 806-816
-
-
Peshavaria, M.1
Gamer, L.2
Henderson, E.3
-
19
-
-
0033960256
-
Early pattern of differentiation in the human pancreas
-
Polak M, Bouchareb-Banaei L, Scharfmann R et al. Early pattern of differentiation in the human pancreas. Diabetes 2000: 49: 225-232.
-
(2000)
Diabetes
, vol.49
, pp. 225-232
-
-
Polak, M.1
Bouchareb-Banaei, L.2
Scharfmann, R.3
-
20
-
-
41649118494
-
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm
-
Spagnoli FM, Brivanlou AH. The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. Development 2008: 135: 451-461.
-
(2008)
Development
, vol.135
, pp. 451-461
-
-
Spagnoli, F.M.1
Brivanlou, A.H.2
-
21
-
-
34347341779
-
Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development
-
McLin VA, Rankin SA, Zorn AM. Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development 2007: 134: 2207-2217.
-
(2007)
Development
, vol.134
, pp. 2207-2217
-
-
McLin, V.A.1
Rankin, S.A.2
Zorn, A.M.3
-
22
-
-
5744240610
-
A conserved role for retinoid signaling in vertebrate pancreas development
-
Stafford D, Hornbruch A, Mueller PR et al. A conserved role for retinoid signaling in vertebrate pancreas development. Dev Genes Evol 2004: 214: 432-441.
-
(2004)
Dev Genes Evol
, vol.214
, pp. 432-441
-
-
Stafford, D.1
Hornbruch, A.2
Mueller, P.R.3
-
23
-
-
0034544776
-
In vitro pancreas formation from Xenopus ectoderm treated with activin and retinoic acid
-
Moriya N, Komazaki S, Takahashi S et al. In vitro pancreas formation from Xenopus ectoderm treated with activin and retinoic acid. Dev Growth Differ 2000: 42: 593-602.
-
(2000)
Dev Growth Differ
, vol.42
, pp. 593-602
-
-
Moriya, N.1
Komazaki, S.2
Takahashi, S.3
-
24
-
-
16244406880
-
Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development
-
Molotkov A, Molotkova N, Duester G. Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development. Dev Dyn 2005: 232: 950-957.
-
(2005)
Dev Dyn
, vol.232
, pp. 950-957
-
-
Molotkov, A.1
Molotkova, N.2
Duester, G.3
-
25
-
-
23944453381
-
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice
-
Martin M, Gallego-Llamas J, Ribes V et al. Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Dev Biol 2005: 284: 399-411.
-
(2005)
Dev Biol
, vol.284
, pp. 399-411
-
-
Martin, M.1
Gallego-Llamas, J.2
Ribes, V.3
-
26
-
-
35648977027
-
Hedgehog signaling in development and homeostasis of the gastrointestinal tract
-
van den Brink GR. Hedgehog signaling in development and homeostasis of the gastrointestinal tract. Physiol Rev 2007: 87: 1343-1375.
-
(2007)
Physiol Rev
, vol.87
, pp. 1343-1375
-
-
van den Brink, G.R.1
-
27
-
-
0037212983
-
Hedgehog signaling in pancreas development
-
Hebrok M. Hedgehog signaling in pancreas development. Mech Dev 2003: 120: 45-57.
-
(2003)
Mech Dev
, vol.120
, pp. 45-57
-
-
Hebrok, M.1
-
28
-
-
34547326050
-
Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms
-
Pan FC, Chen Y, Bayha E et al. Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms. Mech Dev 2007: 124: 518-531.
-
(2007)
Mech Dev
, vol.124
, pp. 518-531
-
-
Pan, F.C.1
Chen, Y.2
Bayha, E.3
-
29
-
-
2942542776
-
Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus
-
Chen Y, Pan FC, Brandes N et al. Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus. Dev Biol 2004: 271: 144-160.
-
(2004)
Dev Biol
, vol.271
, pp. 144-160
-
-
Chen, Y.1
Pan, F.C.2
Brandes, N.3
-
30
-
-
0035174595
-
Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus
-
Zhang J, Rosenthal A, de Sauvage FJ et al. Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus. Dev Biol 2001: 229: 188-202.
-
(2001)
Dev Biol
, vol.229
, pp. 188-202
-
-
Zhang, J.1
Rosenthal, A.2
de Sauvage, F.J.3
-
31
-
-
2642589990
-
Notochord repression of endodermal Sonic hedgehog permits pancreas development
-
Hebrok M, Kim SK, Melton DA. Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev 1998: 12: 1705-1713.
-
(1998)
Genes Dev
, vol.12
, pp. 1705-1713
-
-
Hebrok, M.1
Kim, S.K.2
Melton, D.A.3
-
32
-
-
0035806957
-
Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo
-
Roy S, Qiao T, Wolff C et al. Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo. Curr Biol 2001: 11: 1358-1363.
-
(2001)
Curr Biol
, vol.11
, pp. 1358-1363
-
-
Roy, S.1
Qiao, T.2
Wolff, C.3
-
33
-
-
0036534809
-
Sonic hedgehog is required early in pancreatic islet development
-
diIorio PJ, Moss JB, Sbrogna JL et al. Sonic hedgehog is required early in pancreatic islet development. Dev Biol 2002: 244: 75-84.
-
(2002)
Dev Biol
, vol.244
, pp. 75-84
-
-
diIorio, P.J.1
Moss, J.B.2
Sbrogna, J.L.3
-
34
-
-
41849093727
-
Intra-endodermal interactions are required for pancreatic beta cell induction
-
Chung WS, Stainier DY. Intra-endodermal interactions are required for pancreatic beta cell induction. Dev Cell 2008: 14: 582-593.
-
(2008)
Dev Cell
, vol.14
, pp. 582-593
-
-
Chung, W.S.1
Stainier, D.Y.2
-
35
-
-
0038360823
-
The onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade
-
Jacquemin P, Lemaigre FP, Rousseau GG. The onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade. Dev Biol 2003: 258: 105-116.
-
(2003)
Dev Biol
, vol.258
, pp. 105-116
-
-
Jacquemin, P.1
Lemaigre, F.P.2
Rousseau, G.G.3
-
36
-
-
19244372001
-
Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3
-
Jacquemin P, Durviaux SM, Jensen J et al. Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3. Mol Cell Biol 2000: 20: 4445-4454.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4445-4454
-
-
Jacquemin, P.1
Durviaux, S.M.2
Jensen, J.3
-
37
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
Offield MF, Jetton TL, Labosky PA et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996: 122: 983-995.
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
-
38
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J, Carlsson L, Edlund T et al. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994: 371: 606-609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
-
39
-
-
0029950724
-
The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
-
Ahlgren U, Jonsson J, Edlund H. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/ PDX1-deficient mice. Development 1996: 122: 1409-1416.
-
(1996)
Development
, vol.122
, pp. 1409-1416
-
-
Ahlgren, U.1
Jonsson, J.2
Edlund, H.3
-
40
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
Stoffers DA, Zinkin NT, Stanojevic V et al. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet 1997: 15: 106-110.
-
(1997)
Nat Genet
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
-
41
-
-
0141787919
-
Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1
-
Schwitzgebel VM, Mamin A, Brun T et al. Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1. J Clin Endocrinol Metab 2003: 88: 4398-4406.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4398-4406
-
-
Schwitzgebel, V.M.1
Mamin, A.2
Brun, T.3
-
42
-
-
0034903133
-
Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality, and potentially identifies a multipotent pancreas progenitor cell
-
Yee NS, Yusuff S, Pack M. Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality, and potentially identifies a multipotent pancreas progenitor cell. Genesis 2001: 30: 137-140.
-
(2001)
Genesis
, vol.30
, pp. 137-140
-
-
Yee, N.S.1
Yusuff, S.2
Pack, M.3
-
43
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
Kawaguchi Y, Cooper B, Gannon M et al. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet 2002: 32: 128-134.
-
(2002)
Nat Genet
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
-
44
-
-
0032417268
-
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
-
Krapp A, Knofler M, Ledermann B et al. The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev 1998: 12: 3752-3763.
-
(1998)
Genes Dev
, vol.12
, pp. 3752-3763
-
-
Krapp, A.1
Knofler, M.2
Ledermann, B.3
-
45
-
-
34347345036
-
Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression
-
Wiebe PO, Kormish JD, Roper VT et al. Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Molecular and cellular biology 2007: 27: 4093-4104.
-
(2007)
Molecular and Cellular Biology
, vol.27
, pp. 4093-4104
-
-
Wiebe, P.O.1
Kormish, J.D.2
Roper, V.T.3
-
46
-
-
40949099880
-
Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells
-
Burlison JS, Long Q, Fujitani Y et al. Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev Biol 2008: 316: 74-86.
-
(2008)
Dev Biol
, vol.316
, pp. 74-86
-
-
Burlison, J.S.1
Long, Q.2
Fujitani, Y.3
-
47
-
-
35348985382
-
Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex
-
Masui T, Long Q, Beres TM et al. Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev 2007: 21: 2629-2643.
-
(2007)
Genes Dev
, vol.21
, pp. 2629-2643
-
-
Masui, T.1
Long, Q.2
Beres, T.M.3
-
48
-
-
1642287386
-
Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates
-
Zecchin E, Mavropoulos A, Devos N et al. Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates. Dev Biol 2004: 268: 174-184.
-
(2004)
Dev Biol
, vol.268
, pp. 174-184
-
-
Zecchin, E.1
Mavropoulos, A.2
Devos, N.3
-
49
-
-
9644255692
-
Mutations in PTF1A cause pancreatic and cerebellar agenesis
-
Sellick GS, Barker KT, Stolte-Dijkstra I et al. Mutations in PTF1A cause pancreatic and cerebellar agenesis. Nat Genet 2004: 36: 1301-1305.
-
(2004)
Nat Genet
, vol.36
, pp. 1301-1305
-
-
Sellick, G.S.1
Barker, K.T.2
Stolte-Dijkstra, I.3
-
50
-
-
33845957180
-
Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: An ex vivo gene therapy approach
-
Fodor A, Harel C, Fodor L et al. Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: An ex vivo gene therapy approach. Diabetologia 2007: 50: 121-130.
-
(2007)
Diabetologia
, vol.50
, pp. 121-130
-
-
Fodor, A.1
Harel, C.2
Fodor, L.3
-
51
-
-
34548782660
-
Pancreatic and duodenal homeobox gene 1 induces hepatic dedifferentiation by suppressing the expression of CCAAT/ enhancer-binding protein beta
-
Meivar-Levy I, Sapir T, Gefen-Halevi S et al. Pancreatic and duodenal homeobox gene 1 induces hepatic dedifferentiation by suppressing the expression of CCAAT/enhancer-binding protein beta. Hepatology 2007: 46: 898-905.
-
(2007)
Hepatology
, vol.46
, pp. 898-905
-
-
Meivar-Levy, I.1
Sapir, T.2
Gefen-Halevi, S.3
-
52
-
-
34247597744
-
Ectopic PDX-1 expression in liver ameliorates type 1 diabetes
-
Shternhall-Ron K, Quintana FJ, Perl S et al. Ectopic PDX-1 expression in liver ameliorates type 1 diabetes. J Autoimmun 2007: 28: 134-142.
-
(2007)
J Autoimmun
, vol.28
, pp. 134-142
-
-
Shternhall-Ron, K.1
Quintana, F.J.2
Perl, S.3
-
53
-
-
33744813002
-
Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation
-
Miyatsuka T, Kaneto H, Shiraiwa T et al. Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation. Genes Dev 2006: 20: 1435-1440.
-
(2006)
Genes Dev
, vol.20
, pp. 1435-1440
-
-
Miyatsuka, T.1
Kaneto, H.2
Shiraiwa, T.3
-
54
-
-
33745214464
-
Ectopic pancreas formation in Hes1-knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas
-
Fukuda A, Kawaguchi Y, Furuyama K et al. Ectopic pancreas formation in Hes1-knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas. J Clin Invest 2006: 116: 1484-1493.
-
(2006)
J Clin Invest
, vol.116
, pp. 1484-1493
-
-
Fukuda, A.1
Kawaguchi, Y.2
Furuyama, K.3
-
55
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002: 129: 2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
56
-
-
4444277786
-
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas
-
Esni F, Ghosh B, Biankin AV et al. Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas. Development 2004: 131: 4213-4224.
-
(2004)
Development
, vol.131
, pp. 4213-4224
-
-
Esni, F.1
Ghosh, B.2
Biankin, A.V.3
-
57
-
-
33846910410
-
SOX9 is required for maintenance of the pancreatic progenitor cell pool
-
Seymour PA, Freude KK, Tran MN et al. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A 2007: 104: 1865-1870.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1865-1870
-
-
Seymour, P.A.1
Freude, K.K.2
Tran, M.N.3
-
58
-
-
34547525676
-
Sox9 coordinates a transcriptional network in pancreatic progenitor cells
-
Lynn FC, Smith SB, Wilson ME et al. Sox9 coordinates a transcriptional network in pancreatic progenitor cells. Proc Natl Acad Sci U S A 2007: 104: 10500-10505.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10500-10505
-
-
Lynn, F.C.1
Smith, S.B.2
Wilson, M.E.3
-
59
-
-
0033825383
-
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
-
Schwitzgebel VM, Scheel DW, Conners JR et al. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 2000: 127: 3533-3542.
-
(2000)
Development
, vol.127
, pp. 3533-3542
-
-
Schwitzgebel, V.M.1
Scheel, D.W.2
Conners, J.R.3
-
60
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl G, Dierich A, LeMeur M et al. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 2000: 97: 1607-1611.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
-
61
-
-
33645281942
-
IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas
-
Mellitzer G, Bonne S, Luco RF et al. IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas. EMBO J 2006: 25: 1344-1352.
-
(2006)
EMBO J
, vol.25
, pp. 1344-1352
-
-
Mellitzer, G.1
Bonne, S.2
Luco, R.F.3
-
62
-
-
33748251457
-
The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells
-
Gierl MS, Karoulias N, Wende H et al. The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Genes Dev 2006: 20: 2465-2478.
-
(2006)
Genes Dev
, vol.20
, pp. 2465-2478
-
-
Gierl, M.S.1
Karoulias, N.2
Wende, H.3
-
63
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist A, Li H, Sommer L et al. Notch signalling controls pancreatic cell differentiation. Nature 1999: 400: 877-881.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
-
64
-
-
33847217554
-
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
-
Johansson KA, Dursun U, Jordan N et al. Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev Cell 2007: 12: 457-465.
-
(2007)
Dev Cell
, vol.12
, pp. 457-465
-
-
Johansson, K.A.1
Dursun, U.2
Jordan, N.3
-
65
-
-
0142091542
-
Opposing actions of Arx and Pax4 in endocrine pancreas development
-
Collombat P, Mansouri A, Hecksher-Sorensen J et al. Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes Dev 2003: 17: 2591-2603.
-
(2003)
Genes Dev
, vol.17
, pp. 2591-2603
-
-
Collombat, P.1
Mansouri, A.2
Hecksher-Sorensen, J.3
-
66
-
-
34147092649
-
Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression
-
Collombat P, Hecksher-Sorensen J, Krull J et al. Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression. J Clin Invest 2007: 117: 961-970.
-
(2007)
J Clin Invest
, vol.117
, pp. 961-970
-
-
Collombat, P.1
Hecksher-Sorensen, J.2
Krull, J.3
-
67
-
-
0030897629
-
The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas
-
Sosa-Pineda B, Chowdhury K, Torres M et al. The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 1997: 386: 399-402.
-
(1997)
Nature
, vol.386
, pp. 399-402
-
-
Sosa-Pineda, B.1
Chowdhury, K.2
Torres, M.3
-
68
-
-
23144432613
-
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas
-
Collombat P, Hecksher-Sorensen J, Broccoli V et al. The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas. Development 2005: 132: 2969-2980.
-
(2005)
Development
, vol.132
, pp. 2969-2980
-
-
Collombat, P.1
Hecksher-Sorensen, J.2
Broccoli, V.3
-
69
-
-
34047187934
-
Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas
-
Ait-Lounis A, Baas D, Barras E et al. Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas. Diabetes 2007: 56: 950-959.
-
(2007)
Diabetes
, vol.56
, pp. 950-959
-
-
Ait-Lounis, A.1
Baas, D.2
Barras, E.3
-
70
-
-
0037098974
-
The ghrelin cell: A novel developmentally regulated islet cell in the human pancreas
-
Wierup N, Svensson H, Mulder H et al. The ghrelin cell: A novel developmentally regulated islet cell in the human pancreas. Regul Pept 2002: 107: 63-69.
-
(2002)
Regul Pept
, vol.107
, pp. 63-69
-
-
Wierup, N.1
Svensson, H.2
Mulder, H.3
-
71
-
-
1542267814
-
Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development
-
Prado CL, Pugh-Bernard AE, Elghazi L et al. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc Natl Acad Sci U S A 2004: 101: 2924-2929.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2924-2929
-
-
Prado, C.L.1
Pugh-Bernard, A.E.2
Elghazi, L.3
-
72
-
-
38149057252
-
Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum
-
Wang Q, Elghazi L, Martin S et al. Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum. Dev Dyn 2008: 237: 51-61.
-
(2008)
Dev Dyn
, vol.237
, pp. 51-61
-
-
Wang, Q.1
Elghazi, L.2
Martin, S.3
-
73
-
-
25844456544
-
Genetic determinants of pancreatic epsilon-cell development
-
Heller RS, Jenny M, Collombat P et al. Genetic determinants of pancreatic epsilon-cell development. Dev Biol 2005: 286: 217-224.
-
(2005)
Dev Biol
, vol.286
, pp. 217-224
-
-
Heller, R.S.1
Jenny, M.2
Collombat, P.3
-
75
-
-
0037213587
-
Gene expression cascades in pancreatic development
-
Wilson ME, Scheel D, German MS. Gene expression cascades in pancreatic development. Mech Dev 2003: 120: 65-80.
-
(2003)
Mech Dev
, vol.120
, pp. 65-80
-
-
Wilson, M.E.1
Scheel, D.2
German, M.S.3
-
76
-
-
52049084555
-
Regeneration of pancreatic beta cells
-
Jun HS. Regeneration of pancreatic beta cells. Front Biosci 2008: 13: 6170-6182.
-
(2008)
Front Biosci
, vol.13
, pp. 6170-6182
-
-
Jun, H.S.1
-
77
-
-
34548507937
-
Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage
-
Phillips BW, Hentze H, Rust WL et al. Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage. Stem Cells Dev 2007: 16: 561-578.
-
(2007)
Stem Cells Dev
, vol.16
, pp. 561-578
-
-
Phillips, B.W.1
Hentze, H.2
Rust, W.L.3
-
78
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour KA, Bang AG, Eliazer S et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006: 24: 1392-1401.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
-
79
-
-
33645468639
-
Stem cells and diabetes treatment
-
Madsen OD. Stem cells and diabetes treatment. APMIS 2005: 113: 858-875.
-
(2005)
APMIS
, vol.113
, pp. 858-875
-
-
Madsen, O.D.1
-
80
-
-
33845696388
-
Towards cell therapy for diabetes
-
Madsen OD, Serup P. Towards cell therapy for diabetes. Nat Biotechnol 2006: 24: 1481-1483.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1481-1483
-
-
Madsen, O.D.1
Serup, P.2
-
81
-
-
34548321746
-
Stem cells therapy for type 1 diabetes
-
Lu P, Liu F, Yan L et al. Stem cells therapy for type 1 diabetes. Diabetes Res Clin Pract 2007: 78: 1-7.
-
(2007)
Diabetes Res Clin Pract
, vol.78
, pp. 1-7
-
-
Lu, P.1
Liu, F.2
Yan, L.3
-
82
-
-
36248934727
-
Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation
-
Karnieli O, Izhar-Prato Y, Bulvik S et al. Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation. Stem Cells 2007: 25: 2837-2844.
-
(2007)
Stem Cells
, vol.25
, pp. 2837-2844
-
-
Karnieli, O.1
Izhar-Prato, Y.2
Bulvik, S.3
-
83
-
-
0037820427
-
Bone marrow-derived stem cells initiate pancreatic regeneration
-
Hess D, Li L, Martin M et al. Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol 2003: 21: 763-770.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 763-770
-
-
Hess, D.1
Li, L.2
Martin, M.3
-
84
-
-
43049173752
-
Transplantation of bone marrow derived cells promotes pancreatic islet repair in diabetic mice
-
Gao X, Song L, Shen K et al. Transplantation of bone marrow derived cells promotes pancreatic islet repair in diabetic mice. Biochem Biophys Res Commun 2008: 371: 132-137.
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 132-137
-
-
Gao, X.1
Song, L.2
Shen, K.3
-
85
-
-
36248983813
-
Human marrow-derived mesodermal progenitor cells generate insulin-secreting islet-like clusters in vivo
-
Ai C, Todorov I, Slovak ML et al. Human marrow-derived mesodermal progenitor cells generate insulin-secreting islet-like clusters in vivo. Stem Cells Dev 2007: 16: 757-770.
-
(2007)
Stem Cells Dev
, vol.16
, pp. 757-770
-
-
Ai, C.1
Todorov, I.2
Slovak, M.L.3
-
86
-
-
33751232671
-
Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice
-
Lee RH, Seo MJ, Reger RL et al. Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice. Proc Natl Acad Sci U S A 2006: 103: 17438-17443.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17438-17443
-
-
Lee, R.H.1
Seo, M.J.2
Reger, R.L.3
-
88
-
-
50949121532
-
In vitro cultivation of islet-like cell clusters from human umbilical cord blood-derived mesenchymal stem cells
-
Gao F, Wu DQ, Hu YH et al. In vitro cultivation of islet-like cell clusters from human umbilical cord blood-derived mesenchymal stem cells. Transl Res 2008: 151: 293-302.
-
(2008)
Transl Res
, vol.151
, pp. 293-302
-
-
Gao, F.1
Wu, D.Q.2
Hu, Y.H.3
-
89
-
-
38949203785
-
The spleen -a potential source of new islets for transplantation?
-
Robertson SA, Rowan-Hull AM, Johnson PR. The spleen -a potential source of new islets for transplantation? J Pediatr Surg 2008: 43: 274-278.
-
(2008)
J Pediatr Surg
, vol.43
, pp. 274-278
-
-
Robertson, S.A.1
Rowan-Hull, A.M.2
Johnson, P.R.3
-
90
-
-
52449134233
-
Updates on stem cells and their applications in regenerative medicine
-
Bajada S, Mazakova I, Richardson JB et al. Updates on stem cells and their applications in regenerative medicine. J Tissue Eng Regen Med 2008: 2: 169-183.
-
(2008)
J Tissue Eng Regen Med
, vol.2
, pp. 169-183
-
-
Bajada, S.1
Mazakova, I.2
Richardson, J.B.3
-
92
-
-
39549110217
-
Beta-cell replacement and regeneration: Strategies of cell-based therapy for type 1 diabetes mellitus
-
Limbert C, Path G, Jakob F et al. Beta-cell replacement and regeneration: Strategies of cell-based therapy for type 1 diabetes mellitus. Diabetes Res Clin Pract 2008: 79: 389-399.
-
(2008)
Diabetes Res Clin Pract
, vol.79
, pp. 389-399
-
-
Limbert, C.1
Path, G.2
Jakob, F.3
-
93
-
-
0035479834
-
Transdifferentiation and metaplasia -switching cell types
-
Slack JM, Tosh D. Transdifferentiation and metaplasia -switching cell types. Curr Opin Genet Dev 2001: 11: 581-586.
-
(2001)
Curr Opin Genet Dev
, vol.11
, pp. 581-586
-
-
Slack, J.M.1
Tosh, D.2
-
95
-
-
33746218331
-
Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation
-
Tang DQ, Cao LZ, Chou W et al. Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation. Lab Invest 2006: 86: 829-841.
-
(2006)
Lab Invest
, vol.86
, pp. 829-841
-
-
Tang, D.Q.1
Cao, L.Z.2
Chou, W.3
-
96
-
-
32844462637
-
Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors
-
Tang DQ, Lu S, Sun YP et al. Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors. Lab Invest 2006: 86: 83-93.
-
(2006)
Lab Invest
, vol.86
, pp. 83-93
-
-
Tang, D.Q.1
Lu, S.2
Sun, Y.P.3
-
97
-
-
45249102494
-
Transdifferentiation of pancreatic ductal cells to endocrine beta-cells
-
Bonner-Weir S, Inada A, Yatoh S et al. Transdifferentiation of pancreatic ductal cells to endocrine beta-cells. Biochem Soc Trans 2008: 36: 353-356.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 353-356
-
-
Bonner-Weir, S.1
Inada, A.2
Yatoh, S.3
-
98
-
-
52049107060
-
Pancreatic acinar-to-beta cell transdifferentiation in vitro
-
Minami K, Seino S. Pancreatic acinar-to-beta cell transdifferentiation in vitro. Front Biosci 2008: 13: 5824-5837.
-
(2008)
Front Biosci
, vol.13
, pp. 5824-5837
-
-
Minami, K.1
Seino, S.2
|