Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo

Current Biology

Volumn 11, Issue 17, 2001, Pages 1358-1363

  Roy, Sudipto ^a   Qiao, Tong ^b   Wolff, Christian ^a   Ingham, Philip W ^a,b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035806957     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00402-X     Document Type: Article

References (36)

1. Pancreas: How to get there from the gut?
2. Intercellular signals regulating pancreas development and function
3. Hedgehog signaling regulation of homeodomain protein islet duodenum homeobox-1 expression in pancreatic beta-cells
4. Hedgehog signaling regulation of insulin production by pancreatic beta-cells
5. Developmental biology of the pancreas
6. Notochord repression of endodermal Sonic hedgehog permits pancreas development
7. Activin receptor patterning of foregut organogenesis
8. Notochord to endoderm signaling is required for pancreas development
9. Sonic hedgehog directs specialized mesoderm differentiation in the intestine and pancreas
10. Regulation of pancreas development by hedgehog signaling
11. Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor
12. Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
13. Insulin-promoter-factor I is required for pancreas development in mice
14. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
15. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
16. Pancreas development in the chick embryo
17. IPF1, a homeodomain-containing transactivator of the insulin gene
18. Pancreas development in zebrafish: Early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet
19. Analysis of pancreatic development in living transgenic zebrafish embryos
20. Early appearance of pancreatic hormone-expressing cells in the zebrafish embryo
21. Conservation of PDX-1 structure, function, and expression in zebrafish
22. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
23. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
24. Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut
25. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
26. The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity
27. Analysis of the zebrafish smoothened mutant reveals conserved and divergent function of hedgehog activity
28. Zebrafish smoothened functions in ventral neural tube specification and axon tract formation
29. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
30. Comparative synteny cloning of zebrafish you-too: Mutations in the Hedgehog target gli2 affect ventral forebrain patterning
31. Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish
32. Restricted expression of the homeobox gene prox1 in developing zebrafish
33. Prox1, a prospero-related homeobox gene expressed during mouse development
34. A bipotential precursor population for pancreas and liver within the embryonic endoderm
35. Developmental analysis of ceruloplasmin gene and liver formation in zebrafish
36. Hedgehog signals regulate multiple aspects of gastrointestinal development