-
1
-
-
0032575093
-
Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts
-
Bafico, A., A. Gazit, S. S. Wu-Morgan, A. Yaniv, and S. A. Aaronson. 1998. Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts. Oncogene 16:2819-2825.
-
(1998)
Oncogene
, vol.16
, pp. 2819-2825
-
-
Bafico, A.1
Gazit, A.2
Wu-Morgan, S.S.3
Yaniv, A.4
Aaronson, S.A.5
-
2
-
-
7944230668
-
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
-
Bafico, A., G. Liu, L. Goldin, V. Harris, and S. A. Aaronson. 2004. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 6:497-506.
-
(2004)
Cancer Cell
, vol.6
, pp. 497-506
-
-
Bafico, A.1
Liu, G.2
Goldin, L.3
Harris, V.4
Aaronson, S.A.5
-
3
-
-
0034933057
-
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
-
Bafico, A., G. Liu, A. Yaniv, A. Gazit, and S. A. Aaronson. 2001. Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat. Cell Biol. 3:683-686.
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 683-686
-
-
Bafico, A.1
Liu, G.2
Yaniv, A.3
Gazit, A.4
Aaronson, S.A.5
-
4
-
-
0027067001
-
Ligand-dependent down-regulation of stably transfected human glucocorticoid receptors is associated with the loss of functional glucocorticoid responsiveness
-
Bellingham, D. L., M. Sar, and J. A. Cidlowski. 1992. Ligand-dependent down-regulation of stably transfected human glucocorticoid receptors is associated with the loss of functional glucocorticoid responsiveness. Mol. Endocrinol. 6:2090-2102.
-
(1992)
Mol. Endocrinol
, vol.6
, pp. 2090-2102
-
-
Bellingham, D.L.1
Sar, M.2
Cidlowski, J.A.3
-
5
-
-
0029994517
-
A new member of the frizzled family from Drosophila functions as a Wingless receptor
-
Bhanot, P., M. Brink, C. H. Samos, J. C. Hsieh, Y. Wang, J. P. Macke, D. Andrew, J. Nathans, and R. Nusse. 1996. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382:225-230.
-
(1996)
Nature
, vol.382
, pp. 225-230
-
-
Bhanot, P.1
Brink, M.2
Samos, C.H.3
Hsieh, J.C.4
Wang, Y.5
Macke, J.P.6
Andrew, D.7
Nathans, J.8
Nusse, R.9
-
6
-
-
33746960721
-
A critical role for endocytosis in Wnt signaling
-
Blitzer, J. T., and R. Nusse. 2006. A critical role for endocytosis in Wnt signaling. BMC Cell Biol. 7:28.
-
(2006)
BMC Cell Biol
, vol.7
, pp. 28
-
-
Blitzer, J.T.1
Nusse, R.2
-
7
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
Cadigan, K. M., and R. Nusse. 1997. Wnt signaling: a common theme in animal development. Genes Dev. 11:3286-3305.
-
(1997)
Genes Dev
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
8
-
-
0041470133
-
Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
-
Chen, W., D. ten Berge, J. Brown, S. Ahn, L. A. Hu, W. E. Miller, M. G. Caron, L. S. Barak, R. Nusse, and R. J. Lefkowitz. 2003. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 301:1391-1394.
-
(2003)
Science
, vol.301
, pp. 1391-1394
-
-
Chen, W.1
ten Berge, D.2
Brown, J.3
Ahn, S.4
Hu, L.A.5
Miller, W.E.6
Caron, M.G.7
Barak, L.S.8
Nusse, R.9
Lefkowitz, R.J.10
-
9
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers, H. 2006. Wnt/beta-catenin signaling in development and disease. Cell 127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
10
-
-
8444223093
-
Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
-
Cong, F., L. Schweizer, and H. Varmus. 2004. Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131:5103-5115.
-
(2004)
Development
, vol.131
, pp. 5103-5115
-
-
Cong, F.1
Schweizer, L.2
Varmus, H.3
-
11
-
-
28644444440
-
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
-
Davidson, G., W. Wu, J. Shen, J. Bilic, U. Fenger, P. Stannek, A. Glinka, and C. Niehrs. 2005. Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438:867-872.
-
(2005)
Nature
, vol.438
, pp. 867-872
-
-
Davidson, G.1
Wu, W.2
Shen, J.3
Bilic, J.4
Fenger, U.5
Stannek, P.6
Glinka, A.7
Niehrs, C.8
-
12
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover
-
Di Guglielmo, G. M., C. Le Roy, A. F. Goodfellow, and J. L. Wrana. 2003. Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. Nat. Cell Biol. 5:410-421.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, J.L.4
-
13
-
-
33747339465
-
Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
-
Gordon, M. D., and R. Nusse. 2006. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J. Biol. Chem. 281: 22429-22433.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 22429-22433
-
-
Gordon, M.D.1
Nusse, R.2
-
14
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: Arrows point the way
-
He, X., M. Semenov, K. Tamai, and X. Zeng. 2004. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 131:1663-1677.
-
(2004)
Development
, vol.131
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
16
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
Kawano, Y., and R. Kypta. 2003. Secreted antagonists of the Wnt signalling pathway. J. Cell Sci. 116:2627-2634.
-
(2003)
J. Cell Sci
, vol.116
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
17
-
-
33847019563
-
Multiplicity of the interactions of Wnt proteins and their receptors
-
Kikuchi, A., H. Yamamoto, and S. Kishida. 2007. Multiplicity of the interactions of Wnt proteins and their receptors. Cell. Signal. 19:659-671.
-
(2007)
Cell. Signal
, vol.19
, pp. 659-671
-
-
Kikuchi, A.1
Yamamoto, H.2
Kishida, S.3
-
18
-
-
13444263549
-
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
-
Le Roy, C., and J. L. Wrana. 2005. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat. Rev. Mol. Cell. Biol. 6:112-126.
-
(2005)
Nat. Rev. Mol. Cell. Biol
, vol.6
, pp. 112-126
-
-
Le Roy, C.1
Wrana, J.L.2
-
19
-
-
17644424645
-
The mechanism of endogenous receptor activation functionally distinguishes prototype canonical and non-canonical Wnts
-
Liu, G., A. Banco, and S. A., Aaronson. 2005. The mechanism of endogenous receptor activation functionally distinguishes prototype canonical and non-canonical Wnts. Mol. Cell. Biol. 25:3475-3482.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 3475-3482
-
-
Liu, G.1
Banco, A.2
Aaronson, S.A.3
-
20
-
-
0042131956
-
A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor
-
Liu, G., A. Banco, V. K. Harris, and S. A. Aaronson. 2003. A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Mol. Cell. Biol. 23:5825-5835.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5825-5835
-
-
Liu, G.1
Banco, A.2
Harris, V.K.3
Aaronson, S.A.4
-
21
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao, B., W. Wu, Y. Li, D. Hoppe, P. Stannek, A. Glinka, and C. Niehrs. 2001. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411:321-325.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
Hoppe, D.4
Stannek, P.5
Glinka, A.6
Niehrs, C.7
-
22
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical Wnt signaling pathway
-
Mao, J., J. Wang, B. Liu, W. Pan, G. H. Farr III, C. Flynn, H. Yuan, S. Takada, D. Kimelman, L. Li, and D. Wu. 2001. Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical Wnt signaling pathway. Mol. Cell 7:801-809.
-
(2001)
Mol. Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
Pan, W.4
Farr III, G.H.5
Flynn, C.6
Yuan, H.7
Takada, S.8
Kimelman, D.9
Li, L.10
Wu, D.11
-
23
-
-
33845352082
-
Wnts as ligands: Processing, secretion and reception
-
Mikels, A. J., and R. Nusse. 2006. Wnts as ligands: processing, secretion and reception. Oncogene 25:7461-7468.
-
(2006)
Oncogene
, vol.25
, pp. 7461-7468
-
-
Mikels, A.J.1
Nusse, R.2
-
24
-
-
4344584730
-
WNT and beta-catenin signalling: Diseases and therapies
-
Moon, R. T., A. D. Kohn, G. V. De Ferrari, and A. Kaykas. 2004. WNT and beta-catenin signalling: diseases and therapies. Nat. Rev. Genet. 5:691-701.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
De Ferrari, G.V.3
Kaykas, A.4
-
25
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Morin, P. J., A. B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein, and K. W. Kinzler. 1997. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 275:1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
26
-
-
27144487749
-
Chemokine receptor internalization and intracellular trafficking
-
Neel, N. F., E. Schutyser, J. Sai, G. H. Fan, and A. Richmond. 2005. Chemokine receptor internalization and intracellular trafficking. Cytokine Growth Factor Rev. 16:637-658.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 637-658
-
-
Neel, N.F.1
Schutyser, E.2
Sai, J.3
Fan, G.H.4
Richmond, A.5
-
27
-
-
0034727078
-
An LDL-receptor-related protein mediates Wnt signalling in mice
-
Pinson, K. I., J. Brennan, S. Monkley, B. J. Avery, and W. C. Skarnes. 2000. An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407:535-538.
-
(2000)
Nature
, vol.407
, pp. 535-538
-
-
Pinson, K.I.1
Brennan, J.2
Monkley, S.3
Avery, B.J.4
Skarnes, W.C.5
-
28
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis, P. 2000. Wnt signaling and cancer. Genes Dev. 14:1837-1851.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
29
-
-
0023831574
-
Mechanism of glucocorticoid receptor down-regulation by glucocorticoids
-
Rosewicz, S., A. R. McDonald, B. A. Maddux, I. D. Goldfine, R. L. Miesfeld, and C. D. Logsdon. 1988. Mechanism of glucocorticoid receptor down-regulation by glucocorticoids. J. Biol. Chem. 263:2581-2584.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 2581-2584
-
-
Rosewicz, S.1
McDonald, A.R.2
Maddux, B.A.3
Goldfine, I.D.4
Miesfeld, R.L.5
Logsdon, C.D.6
-
30
-
-
0021042609
-
cDNA cloning of the bovine low density lipoprotein receptor: Feedback regulation of a receptor mRNA
-
Russell, D. W., T. Yamamoto, W. J. Schneider, C. J. Slaughter, M. S. Brown, and J. L. Goldstein. 1983. cDNA cloning of the bovine low density lipoprotein receptor: feedback regulation of a receptor mRNA. Proc. Natl. Acad. Sci. USA 80:7501-7505.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 7501-7505
-
-
Russell, D.W.1
Yamamoto, T.2
Schneider, W.J.3
Slaughter, C.J.4
Brown, M.S.5
Goldstein, J.L.6
-
31
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger, J. 2000. Cell signaling by receptor tyrosine kinases. Cell 103: 211-225.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
32
-
-
0035954281
-
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
-
Semenov, M. V., K. Tamai, B. K. Brott, M. Kuhl, S. Sokol, and X. He. 2001. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr. Biol. 11:951-961.
-
(2001)
Curr. Biol
, vol.11
, pp. 951-961
-
-
Semenov, M.V.1
Tamai, K.2
Brott, B.K.3
Kuhl, M.4
Sokol, S.5
He, X.6
-
33
-
-
0034727104
-
LDL-receptor-related proteins in Wnt signal transduction
-
Tamai, K., M. Semenov, Y. Kato, R. Spokony, C. Liu, Y. Katsuyama, F. Hess, J. P. Saint-Jeannet, and X. He. 2000. LDL-receptor-related proteins in Wnt signal transduction. Nature 407:530-535.
-
(2000)
Nature
, vol.407
, pp. 530-535
-
-
Tamai, K.1
Semenov, M.2
Kato, Y.3
Spokony, R.4
Liu, C.5
Katsuyama, Y.6
Hess, F.7
Saint-Jeannet, J.P.8
He, X.9
-
34
-
-
1642564513
-
A mechanism for Wnt coreceptor activation
-
Tamai, K., X. Zeng, C. Liu, X. Zhang, Y. Harada, Z. Chang, and X. He. 2004. A mechanism for Wnt coreceptor activation. Mol. Cell 13:149-156.
-
(2004)
Mol. Cell
, vol.13
, pp. 149-156
-
-
Tamai, K.1
Zeng, X.2
Liu, C.3
Zhang, X.4
Harada, Y.5
Chang, Z.6
He, X.7
-
35
-
-
0034727099
-
arrow encodes an LDL-receptor-related protein essential for Wingless signalling
-
Wehrli, M., S. T. Dougan, K. Caldwell, L. O'Keefe, S. Schwartz, D. Vaizel-Ohayon, E. Schejter, A. Tomlinson, and S. DiNardo. 2000. arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature 407: 527-530.
-
(2000)
Nature
, vol.407
, pp. 527-530
-
-
Wehrli, M.1
Dougan, S.T.2
Caldwell, K.3
O'Keefe, L.4
Schwartz, S.5
Vaizel-Ohayon, D.6
Schejter, E.7
Tomlinson, A.8
DiNardo, S.9
-
36
-
-
34447526784
-
R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling
-
Wei, Q., C. Yokota, M. V. Semenov, B. Doble, J. Woodgett, and X. He. 2007. R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling. J. Biol. Chem. 282:15903- 15911.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 15903-15911
-
-
Wei, Q.1
Yokota, C.2
Semenov, M.V.3
Doble, B.4
Woodgett, J.5
He, X.6
-
37
-
-
5044228112
-
Wnt signaling in osteoblasts and bone diseases
-
Westendorf, J. J., R. A. Kahler, and T. M. Schroeder. 2004. Wnt signaling in osteoblasts and bone diseases. Gene 341:19-39.
-
(2004)
Gene
, vol.341
, pp. 19-39
-
-
Westendorf, J.J.1
Kahler, R.A.2
Schroeder, T.M.3
-
38
-
-
0037429692
-
Trafficking of the ErbB receptors and its influence on signaling
-
Wiley, H. S. 2003. Trafficking of the ErbB receptors and its influence on signaling. Exp. Cell Res. 284:78-88.
-
(2003)
Exp. Cell Res
, vol.284
, pp. 78-88
-
-
Wiley, H.S.1
-
39
-
-
33746482870
-
Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin
-
Yamamoto, H., H. Komekado, and A. Kikuchi. 2006. Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev. Cell 11:213-223.
-
(2006)
Dev. Cell
, vol.11
, pp. 213-223
-
-
Yamamoto, H.1
Komekado, H.2
Kikuchi, A.3
-
40
-
-
28644439005
-
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
-
Zeng, X., K. Tamai, B. Doble, S. Li, H. Huang, R. Habas, H. Okamura, J. Woodgett, and X. He. 2005. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 438:873-877.
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
Li, S.4
Huang, H.5
Habas, R.6
Okamura, H.7
Woodgett, J.8
He, X.9
-
41
-
-
6344228681
-
N-glycosylation is required for efficient secretion of a novel human secreted glycoprotein, hPAP21
-
Zhou, Y. B., F. Liu, Z. D. Zhu, H. Zhu, X. Zhang, Z. Q. Wang, J. H. Liu, and Z. G. Han. 2004. N-glycosylation is required for efficient secretion of a novel human secreted glycoprotein, hPAP21. FEBS Lett. 576:401-407.
-
(2004)
FEBS Lett
, vol.576
, pp. 401-407
-
-
Zhou, Y.B.1
Liu, F.2
Zhu, Z.D.3
Zhu, H.4
Zhang, X.5
Wang, Z.Q.6
Liu, J.H.7
Han, Z.G.8
|