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Volumn 42, Issue 1, 2008, Pages 17-33

Adiponectin: An adipocytokine with multiple protective functions;Adiponectina: Una adipocitoquina con múltiples funciones protectoras

Author keywords

Adipocytokines; Adiponectin; Adipose tissue; Atherosclerosis; Insulin resistance; Obesity; Type 2 diabetes

Indexed keywords


EID: 51849164091     PISSN: 03252957     EISSN: 03252957     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (115)
  • 1
    • 0036257035 scopus 로고    scopus 로고
    • Adipose tissue: A storage and secretory organ
    • Moreno MJ, Martínez JA. Adipose tissue: a storage and secretory organ. An Sist Sanit Navar 2002; 25 Suppl 1: 29-39.
    • (2002) An Sist Sanit Navar , vol.25 , Issue.SUPPL. 1 , pp. 29-39
    • Moreno, M.J.1    Martínez, J.A.2
  • 3
    • 0029980285 scopus 로고    scopus 로고
    • cDNA cloning and expression of a novel adipose specific collagen-like factor,apM1 (AdiPose Most abundant Gene transcript 1)
    • Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor,apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 1996; 221: 286-9.
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 286-289
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3    Funahashi, T.4    Matsuzawa, Y.5    Matsubara, K.6
  • 4
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995; 270: 26746-9.
    • (1995) J Biol Chem , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 5
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adipose-specific gene dysregulated in obesity
    • Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996; 271: 10697-703.
    • (1996) J Biol Chem , vol.271 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 6
    • 0029836585 scopus 로고    scopus 로고
    • Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
    • Nakano Y, Tobe T, Choi-Miura NH, Mazda T, Tomita M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem 1996; 120: 803-12.
    • (1996) J Biochem , vol.120 , pp. 803-812
    • Nakano, Y.1    Tobe, T.2    Choi-Miura, N.H.3    Mazda, T.4    Tomita, M.5
  • 8
    • 0036750241 scopus 로고    scopus 로고
    • Adiponectin: Its role in metabolism and beyond
    • Stefan N, Stumvoll M. Adiponectin: Its role in metabolism and beyond. Horm Metab Res 2002; 43: 469-74.
    • (2002) Horm Metab Res , vol.43 , pp. 469-474
    • Stefan, N.1    Stumvoll, M.2
  • 9
    • 0033947551 scopus 로고    scopus 로고
    • C1q: Structure, function, and receptors
    • Kishore U, Reid KB. C1q: structure, function, and receptors. Immunopharmacology 2000; 49: 15-170.
    • (2000) Immunopharmacology , vol.49 , pp. 15-170
    • Kishore, U.1    Reid, K.B.2
  • 10
    • 4544241860 scopus 로고    scopus 로고
    • Adiponectin, the missing link in insulin resistance and obesity
    • Gil-Campos M, Cañete R, Gil A. Adiponectin, the missing link in insulin resistance and obesity. Clin Nutr 2004; 23: 963-74.
    • (2004) Clin Nutr , vol.23 , pp. 963-974
    • Gil-Campos, M.1    Cañete, R.2    Gil, A.3
  • 11
    • 0037205414 scopus 로고    scopus 로고
    • Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin: Potential role in the modulation of its insulin-sensitizing activity
    • Wang Y, Xu A, Knight C, Xu LY, Cooper GL. Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin: potential role in the modulation of its insulin-sensitizing activity. J Biol Chem 2002; 277: 19521-9.
    • (2002) J Biol Chem , vol.277 , pp. 19521-19529
    • Wang, Y.1    Xu, A.2    Knight, C.3    Xu, L.Y.4    Cooper, G.L.5
  • 12
    • 0035800745 scopus 로고    scopus 로고
    • Identification and adipocyte differentiation-dependent expression of the unique disialic acid residue in an adipose tissue-specific glycoprotein, adipo Q
    • Sato C, Yasukawa Z, Honda N, Matsuda T, Kitajima K. Identification and adipocyte differentiation-dependent expression of the unique disialic acid residue in an adipose tissue-specific glycoprotein, adipo Q. J Biol Chem 2001; 276: 28849-56.
    • (2001) J Biol Chem , vol.276 , pp. 28849-28856
    • Sato, C.1    Yasukawa, Z.2    Honda, N.3    Matsuda, T.4    Kitajima, K.5
  • 14
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocrine Reviews 2005; 26: 439-51.
    • (2005) Endocrine Reviews , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 15
    • 0037119375 scopus 로고    scopus 로고
    • Oligomerization state-dependent activation of NF-kappa B signaling pathway byadipocyte complement-related protein of 30 kDa (Acrp30)
    • Tsao TS, Murrey HE, Hug C, Lee DH, Lodish HF. Oligomerization state-dependent activation of NF-kappa B signaling pathway byadipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem 2002; 277: 29359-62.
    • (2002) J Biol Chem , vol.277 , pp. 29359-29362
    • Tsao, T.S.1    Murrey, H.E.2    Hug, C.3    Lee, D.H.4    Lodish, H.F.5
  • 16
    • 0141924849 scopus 로고    scopus 로고
    • Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin
    • Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, et al. Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin. J Biol Chem 2003; 278: 40352-63.
    • (2003) J Biol Chem , vol.278 , pp. 40352-40363
    • Waki, H.1    Yamauchi, T.2    Kamon, J.3    Ito, Y.4    Uchida, S.5    Kita, S.6
  • 18
    • 0037984387 scopus 로고    scopus 로고
    • Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin.Implications for metabolic regulation and bioactivity
    • Pajvani UB, Du X, Combs TP, Berg AH, Rajala MW, Schulthess T, et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin.Implications for metabolic regulation and bioactivity. J Biol Chem 2003; 278: 9073-85.
    • (2003) J Biol Chem , vol.278 , pp. 9073-9085
    • Pajvani1    UB, D.X.2    Combs, T.P.3    Berg, A.H.4    Rajala, M.W.5    Schulthess, T.6
  • 19
    • 0036511213 scopus 로고    scopus 로고
    • ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism
    • Berg AH, Combs TP, Scherer PE. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002; 13: 84-9.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 20
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001; 7: 947-53.
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 21
    • 0037902035 scopus 로고    scopus 로고
    • Diurnal and ultradian dynamics of serum adiponectin in healthy men: Comparison with leptin, circulating soluble leptin receptor, and cortisol patterns
    • Gavrila A, Peng CK, Chan JL, Mietus JE, Goldberger AL, Mantzoros CS. Diurnal and ultradian dynamics of serum adiponectin in healthy men: comparison with leptin, circulating soluble leptin receptor, and cortisol patterns. J Clin Endocrinol Metab 2003; 88: 2838-43.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2838-2843
    • Gavrila, A.1    Peng, C.K.2    Chan, J.L.3    Mietus, J.E.4    Goldberger, A.L.5    Mantzoros, C.S.6
  • 22
    • 0036930844 scopus 로고    scopus 로고
    • Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: Effects of insulin and rosiglitazone
    • Motoshima H, Wu X, Sinha MK Hardy VE, Rosato EL, Barbot DJ, et al. Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone. J Clin Endocrinol Metab 2002; 87: 5662-7.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5662-5667
    • Motoshima, H.1    Wu, X.2    Sinha, M.K.3    Hardy, V.E.4    Rosato, E.L.5    Barbot, D.J.6
  • 23
    • 0037356826 scopus 로고    scopus 로고
    • The role of the novel adipocyte-derived adiponectin in human disease
    • Diez JJ, Iglesias P. The role of the novel adipocyte-derived adiponectin in human disease. Eur J Endocrinol 2003; 148: 293-300.
    • (2003) Eur J Endocrinol , vol.148 , pp. 293-300
    • Diez, J.J.1    Iglesias, P.2
  • 24
    • 0036845876 scopus 로고    scopus 로고
    • Pre- and post-translational negative effect of beta-adrenoceptor agonists on adiponectin secretion: In vitro and in vivo studies
    • Delporte ML, Funahashi T, Takahashi M, Matsuzawa Y, Brichard SM. Pre- and post-translational negative effect of beta-adrenoceptor agonists on adiponectin secretion: in vitro and in vivo studies. Biochem J 2002; 367: 677-85.
    • (2002) Biochem J , vol.367 , pp. 677-685
    • Delporte, M.L.1    Funahashi, T.2    Takahashi, M.3    Matsuzawa, Y.4    Brichard, S.M.5
  • 26
    • 0036724336 scopus 로고    scopus 로고
    • Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein
    • Nishizawa H, Shimomura I, Kishida K, Maeda N, Kuriyama H, Nageratani H, et al. Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein. Diabetes 2002; 51: 2734-41.
    • (2002) Diabetes , vol.51 , pp. 2734-2741
    • Nishizawa, H.1    Shimomura, I.2    Kishida, K.3    Maeda, N.4    Kuriyama, H.5    Nageratani, H.6
  • 27
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A, Wang Y, Keshaw H, Yi Xu L, Lam K, Cooper GJS. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003; 112: 91-100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Yi Xu, L.4    Lam, K.5    Cooper, G.J.S.6
  • 28
    • 51849133771 scopus 로고    scopus 로고
    • Human Adiponectin RIA
    • Available in:, accessed June, 2007
    • Millipore. Human Adiponectin RIA. Specifications. 2007. Available in: http://www.millipore.com/catalogue/item/hadp-61hk (accessed June, 2007).
    • (2007) Specifications
  • 29
    • 1642533456 scopus 로고    scopus 로고
    • Evaluation of an enzyme immunometric assay to measure serum adiponectin concentrations
    • Suominen P. Evaluation of an enzyme immunometric assay to measure serum adiponectin concentrations. Clin Chem 2004; 50: 219-21.
    • (2004) Clin Chem , vol.50 , pp. 219-221
    • Suominen, P.1
  • 30
    • 33745813610 scopus 로고    scopus 로고
    • A novel ELISA system for selective measurement of human adiponectin multimers by using proteases
    • Ebinuma H, Miyazaki O, Yago H, Hara K, Yamauchi T, Kadowaki T. A novel ELISA system for selective measurement of human adiponectin multimers by using proteases. Clin Chim Acta 2006; 372: 47-53.
    • (2006) Clin Chim Acta , vol.372 , pp. 47-53
    • Ebinuma, H.1    Miyazaki, O.2    Yago, H.3    Hara, K.4    Yamauchi, T.5    Kadowaki, T.6
  • 31
    • 51849157532 scopus 로고    scopus 로고
    • ALPCO Diagnostics TM, Multimeric, Available in:, accessed June 10, 2007
    • ALPCO Diagnostics TM. Adiponectin (Multimeric. EIA. 2007. Available in: http://www.alpco.com/pdfs/47/47-ADPH-9755.pdf (accessed June 10, 2007).
    • (2007) Adiponectin
  • 32
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003; 423: 762-9.
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3    Tsuchida, A.4    Yokomizo, T.5    Kita, S.6
  • 33
    • 3142701401 scopus 로고    scopus 로고
    • Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity
    • Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, et al. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem 2004; 279: 30817-22.
    • (2004) J Biol Chem , vol.279 , pp. 30817-30822
    • Tsuchida, A.1    Yamauchi, T.2    Ito, Y.3    Hada, Y.4    Maki, T.5    Takekawa, S.6
  • 34
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001; 7: 941-6.
    • (2001) Nat Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 35
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by adipose-derived protein Acrp30
    • Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L. Endogenous glucose production is inhibited by adipose-derived protein Acrp30. J Clin Invest 2001; 108: 1875-81.
    • (2001) J Clin Invest , vol.108 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3    Scherer, P.E.4    Rossetti, L.5
  • 36
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta K, Funashashi T, Bodkin NL, Ortmeyer HK, Arita Y, Hansen BC, et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 2001; 50: 1126-31.
    • (2001) Diabetes , vol.50 , pp. 1126-1131
    • Hotta, K.1    Funashashi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6
  • 37
    • 0037135523 scopus 로고    scopus 로고
    • Disruption of adiponectin causes insulin resistance and neointimal formation
    • Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem 2002; 277: 25863-6.
    • (2002) J Biol Chem , vol.277 , pp. 25863-25866
    • Kubota, N.1    Terauchi, Y.2    Yamauchi, T.3    Kubota, T.4    Moroi, M.5    Matsui, J.6
  • 41
    • 13244284806 scopus 로고    scopus 로고
    • Adiponectin: Journey from an adipocyte secretory protein to biomarker of the metabolic syndrome
    • Trujillo ME, Scherer PE. Adiponectin: journey from an adipocyte secretory protein to biomarker of the metabolic syndrome. J Intern Med 2005; 257: 167-75.
    • (2005) J Intern Med , vol.257 , pp. 167-175
    • Trujillo, M.E.1    Scherer, P.E.2
  • 42
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001; 86: 1930-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3    Hotta, K.4    Matsuzawa, Y.5    Pratley, R.E.6
  • 43
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 2001; 98: 2005-10.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2005-2010
    • Fruebis, J.1    Tsao, T.S.2    Javorschi, S.3    Ebbets-Reed, D.4    Erickson, M.R.5    Yen, F.T.6
  • 46
    • 23844551198 scopus 로고    scopus 로고
    • Adiponectin predicts insulin resistance but not endothelial functions in young, healthy adolescents
    • Singhal A, Jamieson N, Fewtrell M, Deanfield J, Lucas A, Sattar N. Adiponectin predicts insulin resistance but not endothelial functions in young, healthy adolescents. J Clin Endocrinol Metab 2005; 90: 4615-21.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4615-4621
    • Singhal, A.1    Jamieson, N.2    Fewtrell, M.3    Deanfield, J.4    Lucas, A.5    Sattar, N.6
  • 47
    • 1642467862 scopus 로고    scopus 로고
    • Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese Population: The Funagata study
    • Daimon M, Oizumi T, Saitoh T, Kameda W, Hirata A, Yamaguchi H, et al. Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese Population: the Funagata study. Diabetes Care 2003; 26: 2015-20.
    • (2003) Diabetes Care , vol.26 , pp. 2015-2020
    • Daimon, M.1    Oizumi, T.2    Saitoh, T.3    Kameda, W.4    Hirata, A.5    Yamaguchi, H.6
  • 48
    • 0842269790 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived protein, predicts future insulin resistance: Two-year follow-up study in Japanese population
    • Yamamoto Y, Hirose H, Saito I, Nishikai K, Saruta T. Adiponectin, an adipocyte-derived protein, predicts future insulin resistance: two-year follow-up study in Japanese population. J. Clin Endocrinol Metab 2004; 89: 87-90.
    • (2004) J. Clin Endocrinol Metab , vol.89 , pp. 87-90
    • Yamamoto, Y.1    Hirose, H.2    Saito, I.3    Nishikai, K.4    Saruta, T.5
  • 50
    • 33745854236 scopus 로고    scopus 로고
    • Measurement of the high-molecular weight form of adiponectin in plasma is a useful for the prediction of insulin resistance and metabolic syndrome
    • Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, et al. Measurement of the high-molecular weight form of adiponectin in plasma is a useful for the prediction of insulin resistance and metabolic syndrome. Diabetes Care 2006; 29: 1357-62.
    • (2006) Diabetes Care , vol.29 , pp. 1357-1362
    • Hara, K.1    Horikoshi, M.2    Yamauchi, T.3    Yago, H.4    Miyazaki, O.5    Ebinuma, H.6
  • 51
    • 0141539501 scopus 로고    scopus 로고
    • Plasma adiponectin in overweight, nondiabetic individuals with or without insulin resistance
    • Shand BI, Scott RS, Elder PA, George PM. Plasma adiponectin in overweight, nondiabetic individuals with or without insulin resistance. Diabetes Obes Metab 2003; 5: 349-53.
    • (2003) Diabetes Obes Metab , vol.5 , pp. 349-353
    • Shand, B.I.1    Scott, R.S.2    Elder, P.A.3    George, P.M.4
  • 53
    • 17844385849 scopus 로고    scopus 로고
    • Usefulness of serum adiponectin levels as a diagnostic marker of metabolic syndrome in obese Japanese children
    • Ogawa Y, Kikuchi T, Nagasaki K, Hiura M, Tanaka Y, Uchivama M. Usefulness of serum adiponectin levels as a diagnostic marker of metabolic syndrome in obese Japanese children. Hypertens Res 2005; 28: 51-7.
    • (2005) Hypertens Res , vol.28 , pp. 51-57
    • Ogawa, Y.1    Kikuchi, T.2    Nagasaki, K.3    Hiura, M.4    Tanaka, Y.5    Uchivama, M.6
  • 54
    • 33846688711 scopus 로고    scopus 로고
    • Adponectin, insulin resistance an clinical expression of the metabolic syndrome in patients with type 2 diabetes
    • Mojiminiyi OA, Abdella NA, Al Arouj M, Ben Nakhi A. Adponectin, insulin resistance an clinical expression of the metabolic syndrome in patients with type 2 diabetes. Int J Obes 2007; 31: 213-20.
    • (2007) Int J Obes , vol.31 , pp. 213-220
    • Mojiminiyi, O.A.1    Abdella, N.A.2    Al Arouj, M.3    Ben Nakhi, A.4
  • 56
    • 0842263981 scopus 로고    scopus 로고
    • The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
    • Ferré P. The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 2004; 53: S43-S50.
    • (2004) Diabetes , vol.53
    • Ferré, P.1
  • 58
    • 0035462629 scopus 로고    scopus 로고
    • PPARg ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
    • Maeda N, Takahashi M, Funahashi T, Kihara S, Nishizawa H, Kishio K, et al. PPARg ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 2001; 50: 2094-9.
    • (2001) Diabetes , vol.50 , pp. 2094-2099
    • Maeda, N.1    Takahashi, M.2    Funahashi, T.3    Kihara, S.4    Nishizawa, H.5    Kishio, K.6
  • 59
    • 0034810231 scopus 로고    scopus 로고
    • Chromosomal localization, expression pattern and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30
    • Das K, Lin Y, Widen E, Zhang Y, Scherer PE. Chromosomal localization, expression pattern and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochem Biophys Res Commun 2001; 280: 1120-9.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 1120-1129
    • Das, K.1    Lin, Y.2    Widen, E.3    Zhang, Y.4    Scherer, P.E.5
  • 60
    • 4243645912 scopus 로고    scopus 로고
    • Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: A potential mechanism of insulin sensitization
    • Combs TP, Wagner JA, Berger J, Doebber T, Wang WJ, Zhang BB, et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. Endocrinology 2002; 143: 998-1007.
    • (2002) Endocrinology , vol.143 , pp. 998-1007
    • Combs, T.P.1    Wagner, J.A.2    Berger, J.3    Doebber, T.4    Wang, W.J.5    Zhang, B.B.6
  • 61
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 2002; 51: 2968-74.
    • (2002) Diabetes , vol.51 , pp. 2968-2974
    • Yu, J.G.1    Javorschi, S.2    Hevener, A.L.3    Kruszynska, Y.T.4    Norman, R.A.5    Sinha, M.6
  • 62
    • 0036481709 scopus 로고    scopus 로고
    • Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients
    • Yang WS, Jeng CY, Wu TJ, Tanaka S, Funahashi T, Matsuzawa Y, et al. Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care 2002; 25: 376-80.
    • (2002) Diabetes Care , vol.25 , pp. 376-380
    • Yang, W.S.1    Jeng, C.Y.2    Wu, T.J.3    Tanaka, S.4    Funahashi, T.5    Matsuzawa, Y.6
  • 63
    • 0036125944 scopus 로고    scopus 로고
    • Hirose H, Kawai T, Yamamoto Y, Taniyama M, Tomita M, Matsubara K, et al. Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes. Metabolism 2002; 51: 314-7.
    • Hirose H, Kawai T, Yamamoto Y, Taniyama M, Tomita M, Matsubara K, et al. Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes. Metabolism 2002; 51: 314-7.
  • 64
  • 65
    • 0038697822 scopus 로고    scopus 로고
    • Circulating concentration of adiponectin and its expression in subcutaneous adipose tissue in patients with highly active antiretroviral therapy-associated lipodystrophy
    • Sutinen J, Korsheninnikova E, Funahashi T, Matsuzawa Y, Nyman T, Yki-Jarvinen H. Circulating concentration of adiponectin and its expression in subcutaneous adipose tissue in patients with highly active antiretroviral therapy-associated lipodystrophy. J Clin Endocrinol Metab 2003; 88: 1907-10.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1907-1910
    • Sutinen, J.1    Korsheninnikova, E.2    Funahashi, T.3    Matsuzawa, Y.4    Nyman, T.5    Yki-Jarvinen, H.6
  • 66
    • 14544271907 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Balancing the scales
    • Carling D. AMP-activated protein kinase: balancing the scales. Biochimie 2005; 87: 87-91.
    • (2005) Biochimie , vol.87 , pp. 87-91
    • Carling, D.1
  • 67
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002; 8: 1288-95.
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3    Ito, Y.4    Waki, H.5    Uchida, S.6
  • 68
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
    • Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999; 100: 2473-6.
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 69
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
    • Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 2000; 102: 1296-301.
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Okamoto, Y.4    Maeda, K.5    Kuriyama, H.6
  • 70
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi N, Kihara S, Arita Y, Nishida M, Matsuyama A, Okamoto Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001; 103: 1057-63.
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Nishida, M.4    Matsuyama, A.5    Okamoto, Y.6
  • 71
    • 0034284038 scopus 로고    scopus 로고
    • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
    • Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama A, Ouchi N, et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000; 96: 1723-32.
    • (2000) Blood , vol.96 , pp. 1723-1732
    • Yokota, T.1    Oritani, K.2    Takahashi, I.3    Ishikawa, J.4    Matsuyama, A.5    Ouchi, N.6
  • 72
    • 0037129861 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell
    • Arita Y, Kihara S, Ouchi N, Maeda K, Kuriyama H, Okamoto Y, et al. Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation 2002; 105: 2893-8.
    • (2002) Circulation , vol.105 , pp. 2893-2898
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 73
    • 0037020170 scopus 로고    scopus 로고
    • Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis
    • Matsuda M, Shimomura I, Sata M, Arita Y, Nishida M, Maeda N, et al. Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 2002; 277: 37487-91.
    • (2002) J Biol Chem , vol.277 , pp. 37487-37491
    • Matsuda, M.1    Shimomura, I.2    Sata, M.3    Arita, Y.4    Nishida, M.5    Maeda, N.6
  • 74
    • 0242581695 scopus 로고    scopus 로고
    • Adiponectin stimulates production of nitric oxide in vascular endothelial cells
    • Chen H, Montagnani M, Funashashi T, Shimomura I, Quon MJ. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 2003; 278: 45021-6.
    • (2003) J Biol Chem , vol.278 , pp. 45021-45026
    • Chen, H.1    Montagnani, M.2    Funashashi, T.3    Shimomura, I.4    Quon, M.J.5
  • 75
  • 76
    • 0037462684 scopus 로고    scopus 로고
    • Globular adiponectin protected ob/ob mice from diabetes and apoE-deficient mice from atherosclerosis
    • Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, et al. Globular adiponectin protected ob/ob mice from diabetes and apoE-deficient mice from atherosclerosis. J Biol Chem 2003; 278: 2461-8.
    • (2003) J Biol Chem , vol.278 , pp. 2461-2468
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Imai, Y.4    Shimozawa, N.5    Hioki, K.6
  • 77
    • 0037180472 scopus 로고    scopus 로고
    • Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
    • Okamoto Y, Kihara S, Ouchi N, Nishida M, Arita Y, Kumada M, et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 2002; 106: 2767-70.
    • (2002) Circulation , vol.106 , pp. 2767-2770
    • Okamoto, Y.1    Kihara, S.2    Ouchi, N.3    Nishida, M.4    Arita, Y.5    Kumada, M.6
  • 78
    • 0042209622 scopus 로고    scopus 로고
    • A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin
    • Jansson PA, Pellme F, Hammarstedt A, Sandqvist M, Brekke H, Caidahl K, et al. A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin. FASEB J 2003; 17: 1434-40.
    • (2003) FASEB J , vol.17 , pp. 1434-1440
    • Jansson, P.A.1    Pellme, F.2    Hammarstedt, A.3    Sandqvist, M.4    Brekke, H.5    Caidahl, K.6
  • 79
    • 0037432152 scopus 로고    scopus 로고
    • Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue
    • Ouchi N, Kihara S, Funashashi T, Nakamura T, Nishida M, Kumada M, et al. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation 2003; 107: 671-4.
    • (2003) Circulation , vol.107 , pp. 671-674
    • Ouchi, N.1    Kihara, S.2    Funashashi, T.3    Nakamura, T.4    Nishida, M.5    Kumada, M.6
  • 80
    • 0038486152 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, is associated with smoking status in patients with coronary artery disease
    • Miyazaki T, Shimada K, Mokuno H, Daida H. Adipocyte-derived plasma protein, adiponectin, is associated with smoking status in patients with coronary artery disease. Heart 2003; 89: 663-4.
    • (2003) Heart , vol.89 , pp. 663-664
    • Miyazaki, T.1    Shimada, K.2    Mokuno, H.3    Daida, H.4
  • 81
    • 0036139677 scopus 로고    scopus 로고
    • Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease
    • Zoccali C, Mallamaci F, Tripepi G, Benedetto FA, Cutrupi S, Parlongo S, et al. Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. J Am Soc Nephrol 2002; 13: 134-41.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 134-141
    • Zoccali, C.1    Mallamaci, F.2    Tripepi, G.3    Benedetto, F.A.4    Cutrupi, S.5    Parlongo, S.6
  • 84
    • 17044375852 scopus 로고    scopus 로고
    • Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease
    • Matsuzawa Y. Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease. Atheroscler Suppl 2005; 6: 7-14.
    • (2005) Atheroscler Suppl , vol.6 , pp. 7-14
    • Matsuzawa, Y.1
  • 85
    • 23944482982 scopus 로고    scopus 로고
    • Central actions of adipocyte hormones
    • Ahima R. Central actions of adipocyte hormones. Trends Endocrinol Metab 2005; 16: 307-13.
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 307-313
    • Ahima, R.1
  • 86
    • 27144558382 scopus 로고    scopus 로고
    • Fat, keeping the heart healthy?
    • Yuhki K, Kawabe J, Ushikubi F. Fat, keeping the heart healthy? Nat Med 2005; 11: 1048-9.
    • (2005) Nat Med , vol.11 , pp. 1048-1049
    • Yuhki, K.1    Kawabe, J.2    Ushikubi, F.3
  • 88
    • 78149279712 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
    • Russell RR 3rd, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, et al. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest 2004; 114: 495-503.
    • (2004) J Clin Invest , vol.114 , pp. 495-503
    • Russell 3rd, R.R.1    Li, J.2    Coven, D.L.3    Pypaert, M.4    Zechner, C.5    Palmeri, M.6    Giordano, F.J.7
  • 89
    • 27144457438 scopus 로고    scopus 로고
    • Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK and COX-2 dependent mechanisms
    • Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, et al. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK and COX-2 dependent mechanisms. Nat Med 2005; 11: 1096-103.
    • (2005) Nat Med , vol.11 , pp. 1096-1103
    • Shibata, R.1    Sato, K.2    Pimentel, D.R.3    Takemura, Y.4    Kihara, S.5    Ohashi, K.6
  • 90
    • 2542501367 scopus 로고    scopus 로고
    • Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4
    • Xiao CY, Yuhki K, Hara A, Fujino T, Kuriyama S, Yamada T, et al. Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4. Circulation 2004; 109: 2462-8.
    • (2004) Circulation , vol.109 , pp. 2462-2468
    • Xiao, C.Y.1    Yuhki, K.2    Hara, A.3    Fujino, T.4    Kuriyama, S.5    Yamada, T.6
  • 92
    • 19544378172 scopus 로고    scopus 로고
    • The roles of leptin and adiponectin: A novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology
    • Ding X, Saxena NK, Lin S, Xu A, Srinivasan S, Anania FA. The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology. Am J Pathol 2005; 166: 1655-69.
    • (2005) Am J Pathol , vol.166 , pp. 1655-1669
    • Ding, X.1    Saxena, N.K.2    Lin, S.3    Xu, A.4    Srinivasan, S.5    Anania, F.A.6
  • 94
    • 27944477734 scopus 로고    scopus 로고
    • Is Adiponectin level a predictor of nonalcoholic fatty liver disease in nondiabetic male patients?
    • Sargin H, Sargin M, Gozu H, Orcun A, Baloglu G, Ozisik M, et al. Is Adiponectin level a predictor of nonalcoholic fatty liver disease in nondiabetic male patients? World J Gastroenterol 2005; 11: 5874-7.
    • (2005) World J Gastroenterol , vol.11 , pp. 5874-5877
    • Sargin, H.1    Sargin, M.2    Gozu, H.3    Orcun, A.4    Baloglu, G.5    Ozisik, M.6
  • 96
  • 97
    • 1442354888 scopus 로고    scopus 로고
    • Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis
    • Brakenhielm E, Veitonmaki N, Cao R, Kihara S, Matsuzawa Y, Zhivotovsky B, et al. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci USA 2004; 101: 2476-81.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2476-2481
    • Brakenhielm, E.1    Veitonmaki, N.2    Cao, R.3    Kihara, S.4    Matsuzawa, Y.5    Zhivotovsky, B.6
  • 101
    • 33646497663 scopus 로고    scopus 로고
    • Serum adiponectin and leptin levels in Taiwanese breast cancer patients
    • Chen DC, Chung YF, Yeh YT, Chaung HC, Kuo FC, Fu OY, et al. Serum adiponectin and leptin levels in Taiwanese breast cancer patients. Cancer Lett 2006; 237: 109-14.
    • (2006) Cancer Lett , vol.237 , pp. 109-114
    • Chen, D.C.1    Chung, Y.F.2    Yeh, Y.T.3    Chaung, H.C.4    Kuo, F.C.5    Fu, O.Y.6
  • 104
    • 33646190053 scopus 로고    scopus 로고
    • Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells
    • Ogunwobi OO, Beales IL. Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regul Pept 2006; 134: 105-13.
    • (2006) Regul Pept , vol.134 , pp. 105-113
    • Ogunwobi, O.O.1    Beales, I.L.2
  • 105
    • 0036230486 scopus 로고    scopus 로고
    • Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p
    • Mori Y, Otabe S, Dina C, Yasuda K, Populaire C, Lecoeur C, et al. Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p. Diabetes 2002; 51: 1247-55.
    • (2002) Diabetes , vol.51 , pp. 1247-1255
    • Mori, Y.1    Otabe, S.2    Dina, C.3    Yasuda, K.4    Populaire, C.5    Lecoeur, C.6
  • 106
    • 0033652271 scopus 로고    scopus 로고
    • Genomewide search for type 2 diabetes-susceptibility genes in French whites: Evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24
    • Vionnet N, Hani EH, Dupont S, Gallina S, Francke S, Dotte S, et al. Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. Am J Hum Genet 2000; 67: 1470-80.
    • (2000) Am J Hum Genet , vol.67 , pp. 1470-1480
    • Vionnet, N.1    Hani, E.H.2    Dupont, S.3    Gallina, S.4    Francke, S.5    Dotte, S.6
  • 108
    • 0036061598 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in Japanese population
    • Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in Japanese population. Diabetes 2002; 51: 536-40.
    • (2002) Diabetes , vol.51 , pp. 536-540
    • Hara, K.1    Boutin, P.2    Mori, Y.3    Tobe, K.4    Dina, C.5    Yasuda, K.6
  • 109
    • 18644369745 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the Apm1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians
    • Vasseur F, Helbecque N, Dina C, Lobbens S, Delannoy V, Gaget S, et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the Apm1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet 2002; 11: 2607-14.
    • (2002) Hum Mol Genet , vol.11 , pp. 2607-2614
    • Vasseur, F.1    Helbecque, N.2    Dina, C.3    Lobbens, S.4    Delannoy, V.5    Gaget, S.6
  • 110
    • 27744492082 scopus 로고    scopus 로고
    • Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat
    • Stefan N, Machicao F, Staiger H, Machann J, Schick F, Tschritter O, et al. Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. Diabetologia 2005; 48: 2282-91.
    • (2005) Diabetologia , vol.48 , pp. 2282-2291
    • Stefan, N.1    Machicao, F.2    Staiger, H.3    Machann, J.4    Schick, F.5    Tschritter, O.6
  • 111
    • 21344471889 scopus 로고    scopus 로고
    • Damcott CM, Ott SH, Pollin TI, Reinhart LJ, Wang J, O Connell JR, et al. Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish. Diabetes 2005; 54: 2245-50.
    • Damcott CM, Ott SH, Pollin TI, Reinhart LJ, Wang J, O Connell JR, et al. Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish. Diabetes 2005; 54: 2245-50.
  • 112
    • 33644784937 scopus 로고    scopus 로고
    • Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population
    • Vaxillaire M, Dechaume A, Vasseur DV, Lahmidi S, Vatin V, Leprete F, et al. Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population. Diabetes 2006; 55: 856-61.
    • (2006) Diabetes , vol.55 , pp. 856-861
    • Vaxillaire, M.1    Dechaume, A.2    Vasseur, D.V.3    Lahmidi, S.4    Vatin, V.5    Leprete, F.6
  • 113
    • 23944519102 scopus 로고    scopus 로고
    • Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes
    • Hara K, Horikshi M, Kitazato H, Yamauchi T, Ito C, Noda M, et al. Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes. Diabetologia 2005; 48: 1307-14.
    • (2005) Diabetologia , vol.48 , pp. 1307-1314
    • Hara, K.1    Horikshi, M.2    Kitazato, H.3    Yamauchi, T.4    Ito, C.5    Noda, M.6
  • 114
    • 33746414252 scopus 로고    scopus 로고
    • Park JH, Lee M, Kim SW. Non-viral adiponectin gene therapy into obese type 2 diabetic mice ameliorates insulin resistance. J Control Release 2006; 114: 118-25
    • Park JH, Lee M, Kim SW. Non-viral adiponectin gene therapy into obese type 2 diabetic mice ameliorates insulin resistance. J Control Release 2006; 114: 118-25.
  • 115
    • 19944430433 scopus 로고    scopus 로고
    • Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog mammalian adiponectin receptor
    • Narasimhan ML, Coca MA, Jin J, Yamauchi T, Ito Y, Kadowaki T, et al. Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog mammalian adiponectin receptor. Mol Cell 2005; 17: 171-80.
    • (2005) Mol Cell , vol.17 , pp. 171-180
    • Narasimhan, M.L.1    Coca, M.A.2    Jin, J.3    Yamauchi, T.4    Ito, Y.5    Kadowaki, T.6


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