A novel ELISA system for selective measurement of human adiponectin multimers by using proteases

Clinica Chimica Acta

Volumn 372, Issue 1-2, 2006, Pages 47-53

  Ebinuma, Hiroyuki ^a   Miyazaki, Osamu ^a   Yago, Hirokazu ^a   Hara, Kazuo ^b   Yamauchi, Toshimasa ^b   Kadowaki, Takashi ^b  

^a DAIICHI PURE CHEMICALS CO LTD   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Adiponectin; ELISA; Monoclonal antibody; Multimers; Protease

Indexed keywords

ADIPONECTIN; MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; PROTEINASE;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; WESTERN BLOTTING;

ADIPONECTIN; ANTIBODIES, MONOCLONAL; BIOPOLYMERS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS;

EID: 33745813610     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2006.03.014     Document Type: Article

References (18)

1. Scherer P.E., Williams S., Fogliano M., Baldini G., and Lodish H.F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 270 (1995) 26746-26749
2. Hu E., Liang P., and Spiegelman B.M. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271 (1996) 10697-10703
3. Maeda K., Okubo K., Shimomura I., Funahashi T., Matsuzawa Y., and Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 221 (1996) 286-296
4. Nakano Y., Tobe T., Choi-Miura N.H., Mazda T., and Tomita M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem (Tokyo) 120 (1996) 803-812
5. Weyer C., Funahashi T., Tanaka S., et al. Hyperadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86 (2001) 1930-1935
6. Spranger J., Kroke A., Möhlig M., et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 361 (2002) 226-228
7. Daimon M., Yamaguchi H., Oizumi T., et al. Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese population: the Funagata study. Diabetes Care 26 (2003) 2015-2020
8. Arita Y., Kihara S., Ouchi N., et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257 (1999) 79-83
9. Ouchi N., Kihara S., Arita Y., et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 103 (2001) 1057-1063
10. Matsuda M., Shimomura I., Sata M., et al. Role of adiponectin in preventing vascular stenosis-the missing link of adipo-vascular axis. J Biol Chem 277 (2002) 37487-37491
11. Pajvani U.B., Du X., Combs T.P., et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity. J Biol Chem 278 (2003) 9073-9085
12. Tsao T.S., Murrey H.E., Hug C., Lee D.H., and Lodish H.F. Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem 277 (2002) 29359-29362
13. Tsao T.S., Tomas E., Murrey H.E., et al. Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways. J Biol Chem 278 (2003) 50810-50817
14. Waki H., Yamauchi T., Kamon J., et al. Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin. J Biol Chem 278 (2003) 40352-40363
15. Kobayashi H., Ouchi N., Kihara S., et al. Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin. Circ Res 94 (2004) e27-e31
16. Pajvani U.B., Hawkins M., Combs T.P., et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem 279 (2004) 12152-12162
17. Tonelli J., Li W., Kishore P., et al. Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes. Diabetes 53 (2004) 1621-1629
18. Davis B.J. Disc electrophoresis. II. Method and application to human serum proteins. Ann NY Acad Sci 121 (1964) 404-427