Autocrine control of vitamin D metabolism in synovial cells from arthritic patients

Annals of the Rheumatic Diseases

Volumn 58, Issue 6, 1999, Pages 372-378

  Smith, Susan J ^a   Hayes, Michael E ^b   Selby, Peter L ^a   Barbara Mawer, E ^a  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^b MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIFEDIOL; CALCITRIOL; MESSENGER RNA; OXYGENASE; UNCLASSIFIED DRUG; VITAMIN D 24 HYDROXYLASE; VITAMIN D RECEPTOR;

ARTICLE; AUTOCRINE EFFECT; CATABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MACROPHAGE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; SYNOVIOCYTE; VITAMIN D METABOLISM;

EID: 0033038640     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.58.6.372     Document Type: Article

References (22)

1. 3 prevents the in vivo induction of murine experimental encephalomyelitis. J Clin Invest 1991;87:1103-7.
2. 3 prevents insulitis in NOD mice. Diabetes 1992;41:1491-5.
3. 3, KH1060. Endocrinol 1995;136: 866-72.
4. 4 Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. J Nutr 1998;128: 68-72.
5. 3: a pilot study. Arthritis Rheum 1990;33:1723-7.
6. 3 inhibits type II collagen-induced arthritis in rats. FEBS Lett 1994:337:248-50.
7. 7 Mawer EB, Hayes ME, Still PE, Davies M, Lumb GA, Palit J, et al. Evidence for nonrenal synthesis of 1,25-dihydroxyvitamin D in patients with inflammatory arthritis. J Bone Miner Res 1991;6:733-9.
8. 8 Mawer EB, Hayes ME, Berry JL, Davies M. Extra-renal synthesis of 1,25-dihydroxyvitamin D: Implications in inflammatory arthritis and cancer. In: Norman AW, Bouillon R, Thomasset M, eds. Vitamin D-A pluripotent steroid hormone: structural studies, molecular endocrinology and clinical applications. Proceedings of the Ninth Workshop on Vitamin D; 1994, May 28-June 2. Orlanda (FL). Berlin: Walter de Gruyter, 1994;485-93.
9. 3, by synovial fluid macrophages in arthritic diseases. Ann Rheum Dis 1989;48:723-9.
10. 3 synthesis in synovial fluid macrophages from patients with inflammatory arthritis. In: Norman AW, Bouillon R, Thomasset M, eds. Vitamin D-A pluripotent steroid hormone: structural studies, molecular endocrinology and clinical applications. Proceedings of the Ninth Workshop on Vitamin D; 1994, May 28-June 2; Orlando (FL). Berlin: Walter de Gruyter, 1994:145-6.
11. 3 synthesis by synovial fluid macrophages from arthritic joints. Ann Rheum Dis 1992;51: 632-7.
12. 3 synthesis in macrophages from inflammatory arthritic joints. Int J Immunotherapy 1994;10:1-9.
13. 3 by cultured synovial fluid macrophages and fibroblast-like cells from patients with arthritis. Ann Rheum Dis 1992;51: 220-6.
14. 3 synthesis in macrophages from arthritic joints by phorbol ester, dibutryl-cAMP and calcium ionophore (A23187). FEBS Lett 1992;311:71-4.
15. 15 Chen KS, DeLuca HF. Cloning of the human 1α,25-dihydroxvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D responsive elements. Biochim Biophys Acta 1995;1263:1-9.
16. 3 effective on intestine. J Biol Chem 1973;248:6691-6.
17. 17 Mee AP, Webber DM, May C, Bennett D, Sharpe PT, Anderson DC. Detection of canine distemper virus in bone cells in the metaphyses of distemper-infected dogs. J Bone Miner Res 1992;7:829-34.
18. 18 Mee AP, Denton J, Hoyland JA, Davies M, Mawer EB. Quantification of vitamin D receptor mRNA in tissue sections demonstrates the relative limitations of in situ-reverse transcriptase-ploymerase chain reaction. J Pathol 1997; 182:22-8.
19. 3). Clin Chim Acta 1990;190:199-210.
20. 20 Bromley M, Woolley DE. Histopathology of the rheumatoid lesion: Identification of cell types at sites of cartilage erosion. Arthritis Rheum 1984;27:857-63.
21. 21 Woolley DE, Tetlow LC. Observations on the microenvironmental nature of cartilage degradation in rheumatoid lesion. Ann Rheum Dis 1997;56:151-61.
22. 3 in immunosuppression: Lessons from autoimmunity and transplantation. In: Feldman D, Glorieux FH, Pike JW, eds. Vitamin D. San Diego: Academic Press, 1997:1167-81.