From UVs to metastases: Modeling melanoma initiation and progression in the mouse

Journal of Investigative Dermatology

Volumn 128, Issue 10, 2008, Pages 2381-2391

  Zaidi, M Raza ^a   Day, Chi Ping ^a   Merlino, Glenn ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

CANCER IMMUNOTHERAPY; CARCINOGENESIS; CELL INVASION; DISEASE COURSE; ENVIRONMENTAL FACTOR; IMMUNE RESPONSE; MELANOCYTE; MELANOMA; NONHUMAN; PRIORITY JOURNAL; REVIEW; ULTRAVIOLET IRRADIATION;

ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; MELANOMA; MICE; NEOPLASMS, RADIATION-INDUCED; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 51749094162     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2008.177     Document Type: Note

References (78)

1. Ackermann J, Frutschi M, Kaloulis K, McKee T, Trumpp A, Beermann F (2005) Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background. Cancer Res 65:4005-11
2. Bandyopadhyay D, Mishra A, Medrano EE (2004) Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway. Cancer Res 64:7706-10
3. Barcellos-Hoff MH, Brooks AL (2001) Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability. Radiat Res 156:618-27
4. Belinsky SA (2005) Silencing of genes by promoter hypermethylation: key event in rodent and human lung cancer. Carcinogenesis 26:1481-7
5. Bennett DC (2008) How to make a melanoma: what do we know of the primary clonal events? Pigment Cell Melanoma Res 21:27-38
6. Berking C, Takemoto R, Satyamoorthy K, Shirakawa T, Eskandarpour M, Hansson J et al. (2004) Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B. Cancer Res 64:807-11
7. Blackburn JS, Rhodes CH, Coon CI, Brinckerhoff CE (2007) RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis. Cancer Res 67:10849-58
8. Blumenberg M (2006) DNA microarrays in dermatology and skin biology. Omics 10:243-60
9. Brindle K (2008) New approaches for imaging tumour responses to treatment. Nat Rev Cancer 8:94-107
10. Broome Powell M, Gause PR, Hyman P, Gregus J, Lluria-Prevatt M, Nagle R et al. (1999) Induction of melanoma in TPras transgenic mice. Carcinogenesis 20:1747-53
11. Chin L, Garraway LA, Fisher DE (2006) Malignant melanoma: genetics and therapeutics in the genomic era. Genes Dev 20:2149-82
12. Chin L, Tam A, Pomerantz J, Wong M, Holash J, Bardeesy N et al. (1999) Essential role for oncogenic Ras in tumour maintenance. Nature 400:468-72
13. Chudnovsky Y, Adams AE, Robbins PB, Lin Q, Khavari PA (2005) Use of human tissue to assess the oncogenic activity of melanoma-associated mutations. Nat Genet 37:745-9
14. Cranmer LD, Trevor KT, Bandlamuri S, Hersh EM (2005) Rodent models of brain metastasis in melanoma. Melanoma Res 15:325-56
15. Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S et al. (2002) Mutations of the BRAF gene in human cancer. Nature 417:949-54
16. De Fabo EC (2006) Initial studies on an in vivo action spectrum for melanoma induction. Prog Biophys Mol Biol 92:97-104
17. De Fabo EC, Noonan FP, Fears T, Merlino G (2004) Ultraviolet B but not ultraviolet A radiation initiates melanoma. Cancer Res 64:6372-6
18. de Snoo FA, Hayward NK (2005) Cutaneous melanoma susceptibility and progression genes. Cancer Lett 230:153-86
19. Donawho CK, Luo Y, Luo Y, Penning TD, Bauch JL, Bouska JJ et al. (2007) ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models. Clin Cancer Res 13:2728-37
20. Donawho CK, Pride MW, Kripke ML (2001) Persistence of immunogenic pulmonary metastases in the presence of protective antimelanoma immunity. Cancer Res 61:215-21
21. Egger G, Liang G, Aparicio A, Jones PA (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457-63
22. Enk CD, Jacob-Hirsch J, Gal H, Verbovetski I, Amariglio N, Mevorach D et al. (2006) The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytes. Oncogene 25:2601-14
23. Espey DK, Wu XC, Swan J, Wiggins C, Jim MA, Ward E et al. (2007) Annual report to the nation on the status of cancer, 1975-2004, featuring cancer in American Indians and Alaska Natives. Cancer 110:2119-52
24. Esteller M (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8:286-98
25. Feinberg AP (2004) The epigenetics of cancer etiology. Semin Cancer Biol 14:427-32
26. Fidler IJ, Kripke ML (1977) Metastasis results from preexisting variant cells within a malignant tumor. Science 197:893-5
27. Gallagher WM, Bergin OE, Rafferty M, Kelly ZD, Nolan IM, Fox EJ et al. (2005) Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. Carcinogenesis 26:1856-67
28. Gray-Schopfer VC, Cheong SC, Chong H, Chow J, Moss T, Abdel-Malek ZA et al. (2006) Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br J Cancer 95:496-505
29. Gupta GP, Minn AJ, Kang Y, Siegel PM, Serganova I, Cordon-Cardo C et al. (2005) Identifying site-specific metastasis genes and functions. Cold Spring Harb Symp Quant Biol 70:149-58
30. Hachiya A, Kobayashi A, Yoshida Y, Kitahara T, Takema Y, Imokawa G (2004) Biphasic expression of two paracrine melanogenic cytokines, stem cell factor and endothelin-1, in ultraviolet B-induced human melanogenesis. Am J Pathol 165:2099-109
31. Hart IR, Fidler IJ (1980) Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. Cancer Res 40:2281-7
32. Hocker T, Tsao H (2007) Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants. Hum Mutat 28:578-88
33. Hoon DS, Spugnardi M, Kuo C, Huang SK, Morton DL, Taback B (2004) Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients. Oncogene 23:4014-22
34. Hussein MR, Haemel AK, Wood GS (2003) Apoptosis and melanoma: molecular mechanisms. J Pathol 199:275-88
35. Jansen B, Schlagbauer-Wadl H, Kahr H, Heere-Ress E, Mayer BX, Eichler H et al. (1999) Novel Ras antagonist blocks human melanoma growth. Proc Natl Acad Sci USA 96:14019-24
36. Kannan K, Sharpless NE, Xu J, O'Hagan RC, Bosenberg M, Chin L (2003) Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model. Proc Natl Acad Sci USA 100:1221-5
37. Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C et al. (2005) VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438:820-7
38. Kim M, Gans JD, Nogueira C, Wang A, Paik JH, Feng B et al. (2006) Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 125:1269-81
39. Klein-Szanto AJ, Silvers WK, Mintz B (1994) Ultraviolet radiation-induced malignant skin melanoma in melanoma-susceptible transgenic mice. Cancer Res 54:4569-72
40. Kochenderfer JN, Gress RE (2007) A comparison and critical analysis of preclinical anticancer vaccination strategies. Exp Biol Med 232:1130-41
41. Kunisada T, Lu SZ, Yoshida H, Nishikawa S, Nishikawa S, Mizoguchi M et al. (1998) Murine cutaneous mastocytosis and epidermal melanocytosis induced by keratinocyte expression of transgenic stem cell factor. J Exp Med 187:1565-73
42. Langley RR, Fidler IJ (2007) Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis. Endocr Rev 28:297-321
43. Larue L, Beermann F (2007) Cutaneous melanoma in genetically modified animals. Pigment Cell Res 20:485-97
44. Latonen L, Laiho M (2005) Cellular UV damage responses - functions of tumor suppressor p53. Biochim Biophys Acta 1755:71-89
45. Lin JY, Fisher DE (2007) Melanocyte biology and skin pigmentation. Nature 445:843-50
46. Lobo NA, Shimono Y, Qian D, Clarke MF (2007) The biology of cancer stem cells. Annu Rev Cell Dev Biol 23:675-99
47. Lund LP, Timmins GS (2007) Melanoma, long wavelength ultraviolet and sunscreens: controversies and potential resolutions. Pharmacol Ther 114:198-207
48. Maddodi N, Setaluri V (2008) Role of UV in cutaneous melanoma. Photochem Photobiol 84:528-36
49. Matsumura Y, Ananthaswamy HN (2002) Molecular mechanisms of photocarcinogenesis. Front Biosci 7:d765-83
50. Meier F, Nesbit M, Hsu MY, Martin B, Van Belle P, Elder DE et al. (2000) Human melanoma progression in skin reconstructs: biological significance of bFGF. Am J Pathol 156:193-200
51. Melnikova VO, Ananthaswamy HN (2005) Cellular and molecular events leading to the development of skin cancer. Mutat Res 571:91-106
52. Miller AJ, Mihm MC Jr (2006) Melanoma. N Engl J Med 355:51-65
53. Mooi WJ, Peeper DS (2006) Oncogene-induced cell senescence - halting on the road to cancer. N Engl J Med 355:1037-46
54. Muthusamy V, Duraisamy S, Bradbury CM, Hobbs C, Curley DP, Nelson B et al. (2006) Epigenetic silencing of novel tumor suppressors in malignant melanoma. Cancer Res 66:11187-93
55. Nash KT, Welch DR (2006) The KISS1 metastasis suppressor: mechanistic insights and clinical utility. Front Biosci 11:647-59
56. Noonan FP, Recio JA, Takayama H, Duray P, Anver MR, Rush WL et al. (2001) Neonatal sunburn and melanoma in mice. Nature 413:271-2
57. Otsuka T, Takayama H, Sharp R, Celli G, LaRochelle WJ, Bottaro DP et al. (1998) c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype. Cancer Res 58:5157-67
58. Pfeifer GP, You YH, Besaratinia A (2005) Mutations induced by ultraviolet light. Mutat Res 571:19-31
59. Rabinovsky R, Uhr JW, Vitetta ES, Yefenof E (2007) Cancer dormancy: lessons from a B cell lymphoma and adenocarcinoma of the prostate. Adv Cancer Res 97:189-202
60. Ramirez-Montagut T, Chow A, Hirschhorn-Cymerman D, Terwey TH, Kochman AA, Lu S et al. (2006) Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity. J Immunol 176:6434-42
61. Recio JA, Noonan FP, Takayama H, Anver MR, Duray P, Rush WL et al. (2002) Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis. Cancer Res 62:6724-30
62. Rothhammer T, Bosserhoff AK (2007) Epigenetic events in malignant melanoma. Pigment Cell Res 20:92-111
63. Rubbi CP, Milner J (2003) p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage. EMBO J 22:975-86
64. Ruthenburg AJ, Li H, Patel DJ, Allis CD (2007) Multivalent engagement of chromatin modifications by linked binding modules. Nat Rev Mol Cell Biol 8:983-94
65. Sabzevari H, Reisfeld RA (1993) Human cytotoxic T-cells suppress the growth of spontaneous melanoma metastases in SCID/hu mice. Cancer Res 53:4933-7
66. Satyamoorthy K, Meier F, Hsu MY, Berking C, Herlyn M (1999) Human xenografts, human skin and skin reconstructs for studies in melanoma development and progression. Cancer Metastasis Rev 18:401-5
67. Schatton T, Murphy GF, Frank NY, Yamaura K, Waaga-Gasser AM, Gasser M et al. (2008) Identification of cells initiating human melanomas. Nature 451:345-9
68. Shibata S, Okano S, Yonemitsu Y, Onimaru M, Sata S, Nagata-Takeshita H et al. (2006) Induction of efficient antitumor immunity using dendritic cells activated by recombinant Sendai virus and its modulation by exogenous IFN-beta gene. J Immunol 177:3564-76
69. Sotillo R, Garcia JF, Ortega S, Martin J, Dubus P, Barbacid M et al. (2001) Invasive melanoma in Cdk4-targeted mice. Proc Natl Acad Sci USA 98:13312-7
70. Sulem P, Gudbjartsson DF, Stacey SN, Helgason A, Rafnar T, Magnusson KP et al. (2007) Genetic determinants of hair, eye and skin pigmentation in Europeans. Nat Genet 39:1443-52
71. Talmadge JE, Singh RK, Fidler IJ, Raz A (2007) Murine models to evaluate novel and conventional therapeutic strategies for cancer. Am J Pathol 170:793-804
72. Tsutsumida A, Hamada J, Tada M, Aoyama T, Furuuchi K, Kawai Y et al. (2004) Epigenetic silencing of E- and P-cadherin gene expression in human melanoma cell lines. Int J Oncol 25:1415-21
73. van Doorn R, Gruis NA, Willemze R, van der Velden PA, Tensen CP (2005) Aberrant DNA methylation in cutaneous malignancies. Semin Oncol 32:479-87
74. Wang C, Wang MW, Tashiro S, Onodera S, Ikejima T (2005) Roles of SIRT1 and phosphoinositide 3-OH kinase/protein kinase C pathways in evodiamine-induced human melanoma A375-S2 cell death. J Pharmacol Sci 97:494-500
75. Yamashita S, Nomoto T, Abe M, Tatematsu M, Sugimura T, Ushijima T (2004) Persistence of gene expression changes in stomach mucosae induced by short-term N-methyl-N′-nitro-N-nitrosoguanidine treatment and their presence in stomach cancers. Mutat Res 549:185-93
76. Young AR, Chadwick CA, Harrison GI, Hawk JL, Nikaido O, Potten CS (1996) The in situ repair kinetics of epidermal thymine dimers and 6-4 photoproducts in human skin types I and II. J Invest Dermatol 106:1307-13
77. Yu Y, Merlino G (2002) Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model. Cancer Res 62:2951-6
78. Zhang YJ, Chen Y, Ahsan H, Lunn RM, Lee PH, Chen CJ et al. (2003) Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinoma. Int J Cancer 103:440-4