Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 3, 2003, Pages 1221-1225

  Kannan, Karuppiah ^a   Sharpless, Norman E ^a,c   Xu, Jin ^a   O'Hagan, Ronan C ^a   Bosenberg, Marcus ^a,d   Chin, Lynda ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF VERMONT   (United States)

Author keywords

cdk6; P16INK4a; P19ARF; UVB

Indexed keywords

CYCLIN DEPENDENT KINASE 7; PROTEIN P16; PROTEIN P19;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RISK; CARCINOGENESIS; CONTROLLED STUDY; MELANOMA; MOUSE; MUTAGENESIS; NONHUMAN; ONCOGENE H RAS; PHOTOTHERAPY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ANIMALS; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; ENZYME ACTIVATION; MELANOMA; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MUTATION; POLYMERASE CHAIN REACTION; RAS PROTEINS; RETINOBLASTOMA PROTEIN; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P14ARF; ULTRAVIOLET RAYS;

ANIMALIA; MURINAE;

EID: 0037418002     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0336397100     Document Type: Article

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