Regulation by glucose of oscillatory electrical activity and 5-HT/insulin release from single mouse pancreatic islets in absence of functional K ATP channels

Endocrine Journal

Volumn 55, Issue 4, 2008, Pages 639-650

  Rosário, Luís M ^a,b   Barbosa, Rui M ^a,c   Antunes, Célia M ^a,d   Baldeiras, Inês E ^e   Silva, Amélia M ^f   Tomé, Ângelo R ^a,b   Santos, Rosa M ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF ÉVORA   (Portugal)

^e CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^f UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

ATP sensitive K + channels; Bursting electrical activity; Pancreatic cells; Pulsatile insulin release

Indexed keywords

2 OXOISOCAPROIC ACID; ADENOSINE TRIPHOSPHATE; CALCIUM ION; GLIBENCLAMIDE; GLUCOSE; INSULIN; PROTEIN SERINE THREONINE KINASE; SEROTONIN; STAUROSPORINE; SULFONYLUREA; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRIC ACTIVITY; EXTRACELLULAR CALCIUM; INSULIN RELEASE; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OSCILLATION; PANCREAS ISLET; PANCREAS ISLET BETA CELL; POTASSIUM CURRENT; PROTEIN FUNCTION; PROTEIN INTERACTION; SEROTONIN RELEASE; VOLTAGE CLAMP;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CELLS, CULTURED; GLUCOSE; GLYBURIDE; INSULIN; INSULIN-SECRETING CELLS; KETO ACIDS; MEMBRANE POTENTIALS; MICE; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; SEROTONIN; TOLBUTAMIDE;

EID: 51449090932     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K07E-131     Document Type: Article

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