Multiphasic action of glucose and α-ketoisocaproic acid on the cytosolic pH of pancreatic β-cells: Evidence for an acidification pathway linked to the stimulation of Ca2+ influx

Journal of Biological Chemistry

Volumn 271, Issue 15, 1996, Pages 8738-8746

  Salgado, Antonio P ^a   Silva, Amélia M ^a   Santos, Rosa M ^a,b   Rosário, Luis M ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOISOCAPROIC ACID; CALCIUM; TOLBUTAMIDE;

ACIDIFICATION; ARTICLE; CALCIUM TRANSPORT; CELL PH; DEPOLARIZATION; ELECTRIC ACTIVITY; INTRACELLULAR TRANSPORT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMALS; CALCIUM; CELLS, CULTURED; CYTOSOL; FEMALE; GLUCOSE; HYDROGEN-ION CONCENTRATION; ISLETS OF LANGERHANS; KETO ACIDS; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA;

EID: 0029945645     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.15.8738     Document Type: Article

References (70)

1. Wollheim, C B., and Sharp, G. W. G (1981) Physiol Rev. 61, 914-973
2. Prentki, M., and Matschinsky, F. M. (1987) Physiol. Rev 67, 1185-1248
3. Ashcroft, F. M., and Rorsman, P (1989) Prog Biophys Mol Biol. 54, 87 143
4. Smith, J. S., and Pace, C S. (1983) Diabetes 32, 61-66
5. Henquin, J.-C., and Lambert, A. E. (1975) Biochim. Biophys. Acta 381, 437-442
6. Lindstrom, P., and Sehlin, J. (1986) Biochem. J. 239, 199-204
7. Lebrun, P., Ganse, E., Juvent, M., Deleers, M., and Herchuelz, A. (1986) Biochim Biophys. Acta 886, 448-456
8. Best, L., Bone, E. A., Meats, J. E., and Tomlinson, S. (1988) J. Mol. Endocrinol. 1, 33-38
9. Juntti-Berggren, L., Arkhammar, P., Nilsson, T., Rorsman, P., and Berggren, P.-O. (1991) J. Biol Ckem. 266, 23537-23541
10. Juntti-Berggren, L, Rorsman, P., Siffert, W., and Berggren. P.-O. (1992) Biochem. J. 287, 59-66
11. Pace, C. S., Tarvin, J. T., and Smith, J. S. (1983) Am. J Physiol 244, E3-E18
12. Lynch, A. and Best, L. (19901 Biochem. Pharmacol. 40, 411-416
13. Juntti-Berggren. L., Civelek, V. N., Berggren, P.-O., Schultz, V., Corkey, B. E., and Tornheim, K. (1994) J Biol. Chem 269, 14391-14395
14. Rusa, W. B. (1986) Annu. Reu. Physiol. 48, 389-402
15. Misler, S., Gillis, K , and Tabcharani, J. (1989) J. Membr Biol. 109, 135-143
16. Proks, P., Takano, M., and Ashcroft, F M (1994) J. Physiol (Lond.) 475, 33-44
17. Pace, C. S., and Tarvin, J. T. (1983) J. Membr. Biol. 73, 39-49
18. Pace, C. S. (1984) Fed. Proc. 43, 2379-2384
19. Rosário, L. M , and Rojas. E. (1986) FEBS Lett. 200, 203-209
20. Barbosa, R. M., Salgado, A. P., Santos, R. M , and Rosário, L. M. (1993) FEBS Lett. 332, 9-13
21. Santos, R. M., Barbosa, R. M., Antunes, C. M., Silva, A. M., Salgado, A. P., Abrunhosa, A. J., Pereira, F. C., Seiça, R M , and Rosário, L. M. (1996) in Physiology and Pathophysiology of the Islets of Langerhans (Soria, B., ed) Plenum Press. New York, in press
22. Klockner, U , and Isenberg, G. (1994) J. Gen. Physiol 103, 647-663
23. Yamakage, M . Lindeman, K S., Hirshman, C. A., and Croxton, T. L. (1995) Am. J. Physiol 268, L642-L646
24. Deleers, M., Lebrun, P., and Malaisse, W. J. (1983) FEBS Lett 154, 97-100
25. Deleers, M , Lebrun, P., and Malaisse, W. J. (1985) Horm. Metab. Res 17, 391-395
26. Lindstrom, P , and Sehlin, J. (1984) Biochem. J 218, 887-892
27. Rink, T. J., Tsien, R. Y., and Pozzan, T. (1982) J. Cell Biol. 95, 189-196
28. Lynch, A , Meats, J. E., Best, L., and Tomlinson. S. (1989) Biochim Biophys. Acta 1012, 166-170
29. Shepherd, R. M, and Henquin, J.-C. (1995) J. Biol Chem. 270, 7915-7921
30. Juntti-Berggren, L, Kohler, M., Corkey, B. E , Tornheim, K., and Berggren, P.-O. (1994) in Insulin Secretion and Pancreatic B-Cell Research (Flatt, P. R., and Lenzen, S., eds) pp. 145-151, Smith-Gordon, London, UK
31. Wollheim, C. B., Meda, P., and Halban, P. A. (1990) Methods Enzymol. 192, 188-223
32. Silva, A M., Rosário, L. M., and Santos, R. M. (1994) J Biol Chem. 269, 17095-17103
33. Castro, E , Tome, A. R, Miras-Portugal, M. T , and Rosário, L. M. (1994) Pfluegers Arch. Eur. J. Physiol. 426, 524-533
34. Castro, E., Mateo, J., Tomé, A. R., Barbosa, R M., Miras-Portugal, M. T , and Rosário, L. M. (1995) J. Biol. Chem. 270, 5098-5106
35. Grynkiewicz, G., Poenie, M , and Tsien, R Y. (1985) J. Biol. Chem. 260, 3440-3450
36. Wesslen, N., Pipeleers, D. G., Van de Winkel, M., Rorsman, P., and Hellman, B (1987) Acta Physiol. Scand. 131, 230-234
37. Herchuelz, A, Pochet. R., Pastiels, C., and Van Praet, A. (1991) Cell Calcium 12, 577-586
38. Hellman, B., Gylfe, E , Grapengiesser, E., Lund, P.-E., and Berts, A. (1992) Biochim. Biophys. Acta 1113, 295-305
39. Vague, P., Ramahandridona, G., DiCampo. C., and Mahuoud, F. (1977) Harm. Metab. Res. 9, 453-456
40. Lenzen, S. (1978) Diabetes 27, 27-34
41. Gylfe, E (1988) J. Biol. Chem 263, 5044-5048
42. Malaisse Lagae, F , Mathias, P C., and Malaisse, W. J. (1984) Biochem. Biophys. Res. Commun. 123, 1062-1068
43. Arkhammar, P , Nilsson, T , Rorsman, P., and Berggren, P.-O. (1987) J. Biol Chem. 262, 5448-5454
44. Henquin, J -C. (1988) Biochem. Biophys. Res. Commun. 156, 769-775
45. Panten, U., Christians, J., Kriegstein, E., Poser, W., and Hasselbiatt, A. (1974) Diabetologia 10, 149-154
46. Hutton, J. C, Sener, A., and Malaisse, W. J (1980) J. Biol. Chem 255, 7340-7346
47. Ashcroft, F. M., Ashcroft, S. J. H , and Harrison, D. E. (1987) J. Physiol. (Land ) 385, 517-529
48. Busa, W. B., and Nuccitelli, R. (1984) Am. J. Physiol. 246, R409-R438
49. Sener, A., and Malaisse, W. J (1987) Biochem. J. 246, 89-95
50. Sener, A., and Malaisse, W J. (1992) J Biol. Chem 267, 13251-13256
51. Malaisse, W J. (1994) in Nutrient Regulation of Insulin Secretion (Flatt, P. R., ed) pp. 83-100, Portland Press, London
52. Sekme, N., Cirulli, V., Regazzi, R., Brown, L. J., Gine, E., Tamarit-Rodriguez, J , Girotti. M , Marie, S., MacDonald, M. J., Wollheim, C. B., and Rutter, G. A. (1994) J. Biol Chem. 269, 4895-4902
53. Ashcroft, S. J H. (1994) Diabetologia 37, Suppl. 2, S21-S29
54. Moolenar, W. H., Tertoolen, L. G J., and de Laat, S. W. (1984) Nature 312, 371-373
55. Grinstein, S., Cohen, S., Goetz, J. D., Rothstein, A., and Gelfand, E. W. (1985) Proc. Natl Acad. Sci. U. S. A. 82, 1429-1433
56. Swann, K., and Whitaker, M. (1985) Nature 314, 274-277
57. Ganz, M. B., Boyarski, G., Sterzel, R. B , and Boron, W. F. (1989) Nature 337, 648-651
58. Shepherd, R. M., Williams, G. H , and Quinn, S. J (1992) Am J. Physiol. 262, C182-C190
59. Grodsky, G. M. (1970) Vitam. Harm. 28, 37-101
60. Grill, V., Adamson, U., and Cerasi, E. (1978) J. Clin. Invest. 61, 1034-1043
61. Sener, A , Rasschaert, J., and Malaisse, W J. (1990) Biochim Biophys Acta 1019, 42-50
62. Santos, R. M , Rosário, L. M., Nadal, A., Garcia-Sancho, J., Soria, B., and Valdeolmillos, M. (1991) Pfluegers Arch. 418, 417-422
63. Rasschaert, J , and Malaisse, W. J. (1991) Biochem. J. 278, 335-340
64. Hellman, B., and Gylfe, E (1984) Q. J. Exp. Physiol. 69, 867-874
65. Gylfe, E. (1988) J Biol. Chem. 263, 13750-13754
66. Valdeolmillos, M., Santos, R. M, Contreras, D , Soria, B., and Rosário, L. M. (1989) FEBS Lett. 259, 19-23
67. Deleers, M., Lebrun, P., and Malaisse, W. J. (1984) Res. Commun Chem. Pathol. Pharmacol. 44, 83-92
68. Berk, B C , Brock, T. A., Gimbrone, M A., Jr., and Alexander, R W. (1987) J Biol. Chem 262, 5065-5072
69. Ives, H. E , and Daniel, T. O (1987) Proc. Natl. Acad. Sci. U S A. 84, 1950-1954
70. Rosário, L M., Stutzin, A, Cragoe, E J . Jr., and Pollard, H. B (1991) Neuroscience 41, 269-276