Hyperpolarization-activated cyclic nucleotide-gated channels in pancreatic β-cell

Molecular Endocrinology

Volumn 21, Issue 3, 2007, Pages 753-764

  El Kholy, Wasim ^a   MacDonald, Patrick E ^b   Fox, Jocelyn Manning ^a   Bhattacharjee, Alpana ^a   Xue, Tian ^c   Gao, Xiaodong ^a   Zhang, Yi ^a   Stieber, Juliane ^d   Li, Ronald A ^c,f,g   Tsushima, Robert G ^a,e   Wheeler, Michael B ^a,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; CYCLIC NUCLEOTIDE; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; SMALL INTERFERING RNA;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; HEART MUSCLE CELL; HYPERPOLARIZATION; INSULIN RELEASE; INSULINOMA; MEMBRANE POTENTIAL; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE;

RATTUS;

EID: 33847227276     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2006-0258     Document Type: Article

References (47)

1. Ashcroft FM, Rorsman P 1989 Electrophysiology of the pancreatic β-cell. Prog Biophys Mol Biol 54:87-143
2. + channels in pancreatic β-cells: role, regulation and potential as therapeutic targets. Diabetologia 46:1046-1062
3. Yanagihara K, Irisawa H 1980 Inward current activated during hyperpolarization in the rabbit sinoatrial node cell. Pflugers Arch 385:11-19
4. Noma A, Yanagihara K, Irisawa H 1977 Inward current of the rabbit sinoatrial node cell. Pflugers Arch 372:43-51
5. Ludwig A, Zong X, Jeglitsch M, Hofmann F, Biel M 1998 A family of hyperpolarization-activated mammalian cation channels. Nature 393:587-591
6. Santoro B, Liu DT, Yao H, Bartsch D, Kandel ER, Siegelbaum SA, Tibbs GR 1998 Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell 93:717-729
7. Robinson RB, Siegelbaum SA 2003 Hyperpolarization-activated cation currents: from molecules to physiological function. Annu Rev Physiol 65:453-480
8. Ludwig A, Zong X, Hofmann F, Biel M 1999 Structure and function of cardiac pacemaker channels. Cell Physiol Biochem 9:179-186
9. Seifert R, Scholten A, Gauss R, Mincheva A, Lichter P, Kaupp UB 1999 Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis. Proc Natl Acad Sci USA 96:9391-9396
10. Xue T, Marban E, Li RA 2002 Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization. Circ Res 90:1267-1273
11. f and undermines spontaneous beating of neonatal cardiomyocytes. Circulation 107:485-489
12. Biel M, Schneider A, Wahl C 2002 Cardiac HCN channels: structure, function, and modulation. Trends Cardiovasc Med 12:206-212
13. Accili EA, Proenza C, Baruscotti M, DiFrancesco D 2002 From funny current to HCN channels: 20 years of excitation. News Physiol Sci 17:32-37
14. Beaumont V, Zucker RS 2000 Enhancement of synaptic transmission by cyclic AMP modulation of presynaptic Ih channels. Nat Neurosci 3:133-141
15. Nolan MF, Malleret G, Dudman JT, Buhl DL, Santoro B, Gibbs E, Vronskaya S, Buzsaki G, Siegelbaum SA, Kandel ER, Morozov A 2004 A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons. Cell 119:719-732
16. Nolan MF, Malleret G, Lee KH, Gibbs E, Dudman JT, Santoro B, Yin D, Thompson RF, Siegelbaum SA, Kandel ER, Morozov A 2003 The hyperpolarization- activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells. Cell 115:551-564
17. Muller F, Scholten A, Ivanova E, Haverkamp S, Kremmer E, Kaupp UB 2003 HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals. Eur J Neurosci 17:2084-2096
18. Stevens DR, Seifert R, Bufe B, Muller F, Kremmer E, Gauss R, Meyerhof W, Kaupp UB, Lindemann B 2001 Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli. Nature 413:631-635
19. Wainger BJ, DeGennaro M, Santoro B, Siegelbaum SA, Tibbs GR 2001 Molecular mechanism of cAMP modulation of HCN pacemaker channels. Nature 411:805-810
20. f in cells isolated from the rabbit sino-atrial node. J Physiol 377:61-88
21. f) in guinea-pig dissociated sinoatrial node cells. Br J Pharmacol 110:343-349
22. f) by cilobradine and zatebradine. Eur J Pharmacol 478:161-171
23. h channels in synaptic transmission and mossy fiber LTP. Proc Natl Acad Sci USA 99:9538-9543
24. Gonzalez-Iglesias AE, Kretschmannova K, Tomic M, Stojilkovic SS 2006 ZD7288 inhibits exocytosis in an HCN-independent manner and downstream of voltage-gated calcium influx in pituitary lactotrophs. Biochem Biophys Res Commun 346:845-850
25. MacDonald PE, Obermuller S, Vikman J, Galvanovskis J, Rorsman P, Eliasson L 2005 Regulated exocytosis and kiss-and-run of synaptic-like microvesicles in INS-1 and primary rat β-cells. Diabetes 54:736-743
26. + channels in pancreatic β-cells enhances glucose-dependent insulin secretion. J Biol Chem 277:44938-44945
27. Satoh TO, Yamada M 2002 Multiple inhibitory effects of zatebradine (UL-FS 49) on the electrophysiological properties of retinal rod photoreceptors. Pflugers Arch 443:532-540
28. h in rat trigeminal ganglion neurons by an organic blocker. J Membr Biol 160:101-109
29. + channel families regulate insulin secretion. Mol Endocrinol 15:1423-1435
30. Ludwig A, Zong X, Stieber J, Hullin R, Hofmann F, Biel M 1999 Two pacemaker channels from human heart with profoundly different activation kinetics. EMBO J 18:2323-2329
31. ATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) in diabetes mellitus and hyperinsulinism. Hum Mutat 27:220-231
32. ATP channels and insulin secretion: a key role in health and disease. Biochem Soc Trans 34:243-246
33. Furman B, Pyne N, Flatt P, O'Harte F 2004 Targeting β-cell cyclic 3′5′ adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review. J Pharm Pharmacol 56:1477-1492
34. Paolisso G, Nenquin M, Meissner HP, Henquin JC 1985 The effects of cesium chloride on insulin release, ionic fluxes and membrane potential in pancreatic B-cells. Biochim Biophys Acta 844:200-208
35. Macdonald PE, Joseph JW, Rorsman P 2005 Glucose-sensing mechanisms in pancreatic β-cells. Philos Trans R Soc Lond B Biol Sci 360:2211-2225
36. Philipson LH, Kusnetsov A, Larson T, Zeng Y, Westermark G 1993 Human, rodent, and canine pancreatic β-cells express a sodium channel α1-subunit related to a fetal brain isoform. Diabetes 42:1372-1377
37. Leung YM, Ahmed I, Sheu L, Tsushima RG, Diamant NE, Hara M, Gaisano HY 2005 Electrophysiological characterization of pancreatic islet cells in the mouse insulin promoter-green fluorescent protein mouse. Endocrinology 146:4766-4775
38. Kozak JA, Logothetis DE 1997 A calcium-dependent chloride current in insulin-secreting βTC-3 cells. Pflugers Arch 433:679-690
39. 2+ channel. J Biol Chem 281:9361-9372
40. ATP-channel opener preserves β-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose. J Clin Endocrinol Metab 89:795-805
41. ATP channel opener. Diabetes 53:1089-1095
42. Kullin M, Li Z, Bondo Hansen J, Welsh N, Karlsson FA, Sandler S 2003 Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1β mediated suppression-possible involvement of the mitochondrial membrane potential. Diabetologia 46:80-88
43. Wang X, Li H, De Leo D, Guo W, Koshkin V, Fantus IG, Giacca A, Chan CB, Der S, Wheeler MB 2004 Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic β-cell line MIN6. Diabetes 53:129-140
44. Gopel S, Kanno T, Barg S, Galvanovskis J, Rorsman P 1999 Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets. J Physiol 521:717-728
45. Manning Fox JE, Gyulkhandanyan AV, Satin LS, Wheeler MB 2006 Oscillatory membrane potential response to glucose in islet β-cells: a comparison of islet-cell electrical activity in mouse and rat. Endocrinology 147:4655-4663
46. Ishii TM, Takano M, Ohmori H 2001 Determinants of activation kinetics in mammalian hyperpolarization-activated cation channels. J Physiol 537:93-100
47. Li RA, Velez P, Chiamvimonvat N, Tomaselli GF, Marban E 2000 Charged residues between the selectivity filter and S6 segments contribute to the permeation phenotype of the sodium channel. J Gen Physiol 115:81-92