Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic β-cells enhances glucose-dependent insulin secretion

Journal of Biological Chemistry

Volumn 277, Issue 47, 2002, Pages 44938-44945

  MacDonald, Patrick E ^a   Sewing, Sabine ^c   Wang, Jianli ^a   Joseph, Jamie W ^a   Smukler, Simon R ^a   Sakellaropoulos, George ^a   Wang, Jing ^a   Saleh, Monique C ^d   Chan, Catherine B ^d   Tsushima, Robert G ^a,b   Salapatek, Anne Marie F ^a   Wheeler, Michael B ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Lilly Research Laboratories   (Germany)

^d UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GLUCOSE; POTASSIUM;

DEPOLARIZATION;

INSULIN;

ANTIDIABETIC AGENT; CALCIUM ION; GLUCOSE; INSULIN; POTASSIUM ION; PROTEIN SUBUNIT; VOLTAGE GATED POTASSIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVITY; CELL STIMULATION; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRIC ACTIVITY; FEMALE; IMMUNOHISTOCHEMISTRY; INSULIN LIKE ACTIVITY; INSULIN RELEASE; INSULINOMA; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; REPOLARIZATION; TUMOR CELL;

ANIMALIA;

EID: 0347785490     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205532200     Document Type: Article

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