Electrophysiological and immunocytochemical evidence for P2X purinergic receptors in pancreatic β cells

Pancreas

Volumn 36, Issue 3, 2008, Pages 279-283

  Silva, Amélia M ^a,b   Rodrigues, Ricardo J ^c   Tomé, Ângelo R ^c,d   Cunha, Rodrigo A ^c,e   Misler, Stanley ^f   Rosário, Luís M ^c,d   Santos, Rosa M ^c,d  

^a UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e UNIVERSITY OF COIMBRA   (Portugal)

^f WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

, methylene ATP; ATP; ATP gated ion channels; Immunocytochemistry; P2X receptors; Pancreatic cell

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; GLUCOSE; INSULIN; NYSTATIN; PURINERGIC P2X RECEPTOR; PURINERGIC P2X1 RECEPTOR; PURINERGIC P2X3 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INSULIN RELEASE; ION CURRENT; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PATCH CLAMP; PRIORITY JOURNAL; VOLTAGE CLAMP; WHOLE CELL;

ADENOSINE TRIPHOSPHATE; ANIMALS; ELECTROPHYSIOLOGY; FEMALE; GLUCOSE; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; ION CHANNEL GATING; MICE; PATCH-CLAMP TECHNIQUES; RECEPTORS, PURINERGIC P2; SWINE;

EID: 41149170881     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e31815a8473     Document Type: Article

References (42)

1. Rojas E, Santos RM, Stutzin A, et al. Optical detection of ATP release from stimulated endocrine cells. A universal marker of exocytotic secretion of hormones. In: Latorre E, ed. Ionic Channels in Cells and Model Systems. New York: Plenum Press; 1986:163-178.
2. Hazama A, Hayashi S, Okada Y. Cell surface measurements of ATP release from single pancreatic beta cells using a novel biosensor technique. Pflugers Arch. 1998;437:31-35.
3. Kuromi H, Mizuno N, Seino S. A monitor of secretion from single pancreatic beta-cells. Diabetes. 1995;44:1213-1217.
4. Miller RE. Pancreatic neuroendocrinology: peripheral neural mechanisms in the regulation of the Islets of Langerhans. Endocr Rev. 1981;2:471-494.
5. Detimary P, Jonas JC, Henquin JC. Stable and diffusible pools of nucleotides in pancreatic islet cells. Endocrinology. 1996;137:4671-4676.
6. Tahani HM. The purinergic nerve hypothesis and insulin secretion. Z Ernahrungswiss. 1979;18:128-138.
7. Burnstock G. Purinergic signalling-an overview. Novartis Found Symp. 2006;276:26-48.
8. Costanzi S, Mamedova L, Gao ZG, et al. Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling. J Med Chem. 2004;47:5393-5404.
9. Khakh BS, North RA. P2X receptors as cell-surface ATP sensors in health and disease. Nature. 2006;442:527-532.
10. North RA. Molecular physiology of P2X receptors. Physiol Rev. 2002;82:1013-1067.
11. Roberts JA, Vial C, Digby HR, et al. Molecular properties of P2X receptors. Pflugers Arch. 2006;452:486-500.
12. North RA, Surprenant A. Pharmacology of cloned P2X receptors. Annu Rev Pharmacol Toxicol. 2000;40:563-580.
13. Burnstock G. Historical review: ATP as a neurotransmitter. Trends Pharmacol Sci. 2006;27:166-176.
14. Fernandez-Alvarez J, Hillaire-Buys D, Loubatieres-Mariani MM, et al. P2 receptor agonists stimulate insulin release from human pancreatic islets. Pancreas. 2001;22:69-71.
15. Petit P, Hillaire-Buys D, Manteghetti M, et al. Evidence for two different types of P2 receptors stimulating insulin secretion from pancreatic B cell. Br J Pharmacol. 1998;125:1368-1374.
16. Bertrand G, Gross R, Chapal J, et al. Difference in the potentiating effect of adenosine triphosphate and alpha, beta-methylene ATP on the biphasic insulin response to glucose. Br J Pharmacol. 1989;98:998-1004.
17. Coutinho-Silva R, Parsons M, Robson T, et al. Changes in expression of P2 receptors in rat and mouse pancreas during development and ageing. Cell Tissue Res. 2001;306:373-383.
18. Arkhammar P, Hallberg A, Kindmark H, et al. Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate - sensitive Ca2+ pool. Biochem J. 1990;265:203-211.
19. Poulsen CR, Bokvist K, Olsen HL, et al. Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells. Diabetes. 1999;48:2171-2181.
20. Li GD, Milani D, Dunne MJ, et al. Extracellular ATP causes Ca2(+)-dependent and -independent insulin secretion in RINm5F cells. Phospholipase C mediates Ca2+ mobilization but not Ca2+ influx and membrane depolarization. J Biol Chem. 1991;266:3449-3457.
21. Silva AM, Rosario LM, Santos RM. Background Ca2+ influx mediated by a dihydropyridine- and voltage-insensitive channel in pancreatic beta-cells. Modulation by Ni2+, diphenylamine-2-carboxylate, and glucose metabolism. J Biol Chem. 1994;269:17095-17103.
22. Ricordi C, Lacy PE, Finke EH, et al. Automated method for isolation of human pancreatic islets. Diabetes. 1988;37:413-420.
23. Salgado A, Silva AM, Santos RM, et al. Multiphasic action of glucose and alpha-ketoisocaproic acid on the cytosolic pH of pancreatic beta-cells. Evidence for an acidification pathway linked to the stimulation of Ca2+ influx. J Biol Chem. 1996;271:8738-8746.
24. Gopel S, Kanno T, Barg S, et al. Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets. J Physiol. 1999;521:717-728.
25. Pipeleers DG, Van de Winkel M. Separation of pancreatic islet cells according to functional characteristics. Cell Separation: Methods and Selected Applications. Academic Press; 1987:119-140.
26. Silva AM, Liu-Gentry J, Dickey AS, et al. Alpha-latrotoxin increases spontaneous and depolarization-evoked exocytosis from pancreatic islet beta-cells. J Physiol. 2005;565:783-799.
27. Rodrigues RJ, Almeida T, Richardson PJ, et al. Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J Neurosci. 2005;25:6286-6295.
28. Torres GE, Egan TM, Voigt MM. Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners. J Biol Chem. 1999;274:6653-6659.
29. Geschwind JF, Hiriart M, Glennon MC, et al. Selective activation of Ca2+ influx by extracellular ATP in a pancreatic beta-cell line (HIT). Biochim Biophys Acta. 1989;1012:107-115.
30. Wang CZ, Namba N, Gonoi T, et al. Cloning and pharmacological characterization of a fourth P2X receptor subtype widely expressed in brain and peripheral tissues including various endocrine tissues. Biochem Biophys Res Commun. 1996;220:196-202.
31. Petit P, Bertrand G, Schmeer W, et al. Effects of extracellular adenine nucleotides on the electrical, ionic and secretory events in mouse pancreatic beta-cells. Br J Pharmacol. 1989;98:875-882.
32. Léon C, Freund M, Latchoumanin O, et al. The P2Y1 receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice. Purinergic Signalling. 2005;1:145-151.
33. Chen XK, Wang LC, Zhou Y, et al. Activation of GPCRs modulates quantal size in chromaffin cells through G(betagamma) and PKC. Nat Neurosci. 2005;8:1160-1168.
34. Gong Q, Kakei M, Koriyama N, et al. P2Y-purinoceptor mediated inhibition of L-type Ca2+ channels in rat pancreatic beta-cells. Cell Struct Funct. 2000;25:279-289.
35. Tome AR, Castro E, Santos RM, et al. Functional distribution of Ca2+-coupled P2 purinergic receptors among adrenergic and noradrenergic bovine adrenal chromaffin cells. BMC Neurosci. 2007;8:39.
36. Hillaire-Buys D, Chapal J, Bertrand G, et al. Purinergic receptors on insulin-secreting cells. Fundam Clin Pharmacol. 1994;8:117-127.
37. Hellman B, Gylfe E, Wesslen N, et al. Plasma membrane associated ATP as a regulator of the secretory activity of the pancreatic beta-cell. Exp Clin Endocrinol. 1989;93:125-135.
38. Terasawa E, Keen KL, Grendell RL, et al. Possible role of 5′;-adenosine triphosphate in synchronization of Ca2+ oscillations in primate luteinizing hormone-releasing hormone neurons. Mol Endocrinol. 2005;19:2736-2747.
39. Hellman B, Dansk H, Grapengiesser E. Pancreatic beta-cells communicate via intermittent release of ATP. Am J Physiol Endocrinol Metab. 2004;286:E759-E765.
40. Rosario LM, Atwater I, Scott AM. Pulsatile insulin release and electrical activity from single ob/ob mouse islets of Langerhans. In: Atwater I, Rojas E, Soria B, eds. Biophysics of the Pancreatic B-Cells. New York: Plenum Publishing Corporation; 1986:413-425.
41. Santos RM, Rosario LM, Nadal A, et al. Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets. Pflugers Arch. 1991;418:417-422.
42. Barbosa RM, Silva AM, Tome AR, et al. Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics. J Physiol. 1998;510:135-143.