Inhibition of insulin-like growth factor I receptor tyrosine kinase by ethanol

Biochemical Pharmacology

Volumn 68, Issue 10, 2004, Pages 2009-2017

  Rubin, Raphael ^a   Harrison, Rob ^b   Chen, Xian Feng ^b   Corzitotto, Joseph ^a   Hoek, Jan B ^a   Hallak, Hazem ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Cerebellar granule neurons; Ethanol; Insulin receptor; Insulin like growth factor I receptor; Tyrosine kinase

Indexed keywords

ALCOHOL; INSULIN RECEPTOR; PEPTIDE; SOMATOMEDIN C RECEPTOR; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BACULOVIRUS; BINDING AFFINITY; COMPUTER MODEL; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STIMULATION;

ANIMALS; CELLS, CULTURED; ETHANOL; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RATS; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN;

EID: 5144234640     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.06.032     Document Type: Article

References (54)

1. J. Luo, and M.W. Miller Growth factor-mediated neural proliferation: target of ethanol toxicity Brain Res. Brain Res. Rev. 27 1998 157 167
2. J.H. Hannigan, and D.R. Armant Alcohol in pregnancy and neonatal outcome Semin. Neonatol. 5 2000 243 254
3. R. Rubin, and R. Baserga Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity Lab. Invest. 73 1995 311 331
4. D. LeRoith, H. Werner, D. Beitner-Johnson, and C.T. Roberts Jr. Molecular and cellular aspects of the insulin-like growth factor I receptor Endocr. Rev. 16 1995 143 163
5. M. Resnicoff, S. Cui, D. Coppola, J.B. Hoek, and R. Rubin Ethanol-induced inhibition of cell proliferation is modulated by insulin-like growth factor-I receptor levels Alcohol Clin. Exp. Res. 20 1996 961 966
6. K. Banerjee, L. Mohr, J.R. Wands, and S.M. de la Monte Ethanol inhibition of insulin signaling in hepatocellular carcinoma cells Alcohol Clin. Exp. Res. 22 1998 2093 2101
7. F.X. Zhang, R. Rubin, and T.A. Rooney Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-like growth factor 1 signaling J. Neurochem. 71 1998 196 204
8. S.V. Bhave, L. Ghoda, and P.L. Hoffman Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action J. Neurosci. 19 1999 3277 3286
9. S.M. de la Monte, N. Ganju, S. Tanaka, K. Banerjee, P.J. Karl, and N.V. Brown Differential effects of ethanol on insulin-signaling through the insulin receptor substrate-1 Alcohol Clin. Exp. Res. 23 1999 770 777
10. A.E. Seiler, B.N. Ross, J.S. Green, and R. Rubin Differential effects of ethanol on insulin-like growth factor-I receptor signaling Alcohol Clin. Exp. Res. 24 2000 140 148
11. A.E. Seiler, B.N. Ross, and R. Rubin Inhibition of insulin-like growth factor-1 receptor and IRS-2 signaling by ethanol in SH-SY5Y neuroblastoma cells J. Neurochem. 76 2001 573 581
12. H. Hallak, A.E. Seiler, J.S. Green, A. Henderson, B.N. Ross, and R. Rubin Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cells Alcohol Clin. Exp. Res. 25 2001 1058 1064
13. M. Resnicoff, C. Sell, D. Ambrose, R. Baserga, and R. Rubin Ethanol inhibits the autophosphorylation of the insulin-like growth factor 1 (IGF-1) receptor and IGF-1-mediated proliferation of 3T3 cells J. Biol. Chem. 268 1993 21777 21782
14. M. Resnicoff, M. Rubini, R. Baserga, and R. Rubin Ethanol inhibits insulin-like growth factor-1-mediated signalling and proliferation of C6 rat glioblastoma cells Lab. Invest. 71 1994 657 662
15. J. Luo, and M.W. Miller Platelet-derived growth factor-mediated signal transduction underlying astrocyte proliferation: site of ethanol action J. Neurosci. 19 1999 10014 10025
16. G. Ghiselli, J. Chen, M. Kaou, H. Hallak, and R. Rubin Ethanol inhibits fibroblast growth factor-induced proliferation of aortic smooth muscle cells Arterioscler. Thromb. Vasc. Biol. 23 2003 1808 1813
17. A. Ullrich, A. Gray, A.W. Tam, T. Yang-Feng, M. Tsubokawa, and C. Collins Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity EMBO J. 5 1986 2503 2512
18. H. Werner, M. Adamo, C.T. Roberts Jr., and D. LeRoith Molecular and cellular aspects of insulin-like growth factor action Vitam. Horm. 48 1994 1 58
19. A.E. Seiler, A. Henderson, and R. Rubin Ethanol inhibits insulin receptor tyrosine kinase Alcohol Clin. Exp. Res. 24 2000 1869 1872
20. S.R. Hubbard, L. Wei, L. Ellis, and W.A. Hendrickson Crystal structure of the tyrosine kinase domain of the human insulin receptor Nature 372 1994 746 754
21. S. Favelyukis, J.H. Till, S.R. Hubbard, and W.T. Miller Structure and autoregulation of the insulin-like growth factor 1 receptor kinase Nat. Struct. Biol. 8 2001 1058 1063
22. S. Munshi, M. Kornienko, D.L. Hall, J.C. Reid, L. Waxman, and S.M. Stirdivant Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificity J. Biol. Chem. 277 2002 38797 38802
23. L. Wei, S.R. Hubbard, W.A. Hendrickson, and L. Ellis Expression, characterization, and crystallization of the catalytic core of the human insulin receptor protein-tyrosine kinase domain J. Biol. Chem. 270 1995 8122 8130
24. A. Pautsch, A. Zoephel, H. Ahorn, W. Spevak, R. Hauptmann, and H. Nar Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation Structure 9 2001 955 965
25. S.R. Hubbard, and J.H. Till Protein tyrosine kinase structure and function Annu. Rev. Biochem. 69 2000 373 398
26. W. Lopaczynski, C. Terry, and P. Nissley Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain Biochem. Biophys. Res. Commun. 279 2000 955 960
27. F.X. Zhang, R. Rubin, and T.A. Rooney N-methyl-d-aspartate inhibits apoptosis through activation of phosphatidylinositol 3-kinase in cerebellar granule neurons. A role for insulin receptor substrate-1 in the neurotrophic action of N-methyl-d-aspartate and its inhibition by ethanol J. Biol. Chem. 273 1998 26596 26602
28. R.W. Harrison, and I.T. Weber Molecular dynamics simulations of HIV-1 protease with peptide substrate Protein Eng. 7 1994 1353 1363
29. R.W. Harrison, I.V. Kourinov, and L.C. Andrews The Fourier-Green's function and the rapid evaluation of molecular potentials Protein Eng. 7 1994 359 369
30. R.W. Harrison, C.C. Reed, and I.T. Weber Analysis of comparative modeling predictions for CASP2 targets 1, 3, 9, and 17 Proteins 1 Suppl 1997 68 73
31. I.T. Weber Molecular mechanics calculations on protein-ligand complexes 1998 Kluwer Academic Publishers Dordrecht, The Netherlands
32. D.S. Dwyer, and R.J. Bradley Chemical properties of alcohols and their protein binding sites Cell Mol. Life Sci. 57 2000 265 275
33. B. Xu, V.G. Bird, and W.T. Miller Substrate specificities of the insulin and insulin-like growth factor 1 receptor tyrosine kinase catalytic domains J. Biol. Chem. 270 1995 29825 29830
34. H. Meyer On the theory of alcohol narcosis. What property of anesthetics produces their anesthetic action? Arch Exper. Path U (Naunyn-Schmiedeberg) 42 1899 109 118
35. N.P. Franks, A. Jenkins, E. Conti, W.R. Lieb, and P. Brick Structural basis for the inhibition of firefly luciferase by a general anesthetic Biophys. J. 75 1998 2205 2211
36. N.P. Franks, and W.R. Lieb Molecular and cellular mechanisms of general anaesthesia Nature 367 1994 607 614
37. C.D. Stubbs, and S.J. Slater Ethanol and protein kinase C Alcohol Clin. Exp. Res. 23 1999 1552 1560
38. C.D. Stubbs, and R. Rubin Effect of ethanol on platelet phospholipase A2 Lipids 27 1992 255 260
39. M.D. Krasowski, and N.L. Harrison General anaesthetic actions on ligand-gated ion channels Cell Mol. Life Sci. 55 1999 1278 1303
40. I. Diamond, and A.S. Gordon Cellular and molecular neuroscience of alcoholism Physiol. Rev. 77 1997 1 20
41. M.H. Abraham, W.R. Lieb, and N.P. Franks Role of hydrogen bonding in general anesthesia J. Pharm. Sci. 80 1991 719 724
42. R.G. Eckenhoff, and J.S. Johansson Molecular interactions between inhaled anesthetics and proteins Pharmacol. Rev. 49 1997 343 367
43. S.C. Wood, P.H. Tonner, A.J. de Armendi, B. Bugge, and K.W. Miller Channel inhibition by alkanols occurs at a binding site on the nicotinic acetylcholine receptor Mol. Pharmacol. 47 1995 121 130
44. M.J. Wick, S.J. Mihic, S. Ueno, M.P. Mascia, J.R. Trudell, and S.J. Brozowski Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proc. Natl. Acad. Sci. USA 95 1998 6504 6509
45. M. Scheller, and S.A. Forman Butanol effects on gamma-amino butyric acid concentration-responses in human alpha1beta2gamma2L gamma-amino butyric acid type A receptors with a mutation at alpha1S270 Neurosci. Lett. 297 2001 179 182
46. S.A. Forman, and Q. Zhou Nicotinic receptor pore mutations create a sensitive inhibitory site for ethanol Alcohol Clin. Exp. Res. 24 2000 1363 1368
47. T. Harris, M. Shahidullah, J.S. Ellingson, and M. Covarrubias General anesthetic action at an internal protein site involving the S4-S5 cytoplasmic loop of a neuronal K(+) channel J. Biol. Chem. 275 2000 4928 4936
48. Q. Ye, V.V. Koltchine, S.J. Mihic, M.P. Mascia, M.J. Wick, and S.E. Finn Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267 J. Biol. Chem. 273 1998 3314 3319
49. M.F. Wilkemeyer, and M.E. Charness Characterization of ethanol-sensitive and insensitive fibroblast cell lines expressing human L1 J. Neurochem. 71 1998 2382 2391
50. M. Mohammadi, G. McMahon, L. Sun, C. Tang, P. Hirth, and B.K. Yeh Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors Science 276 1997 955 960
51. N. Gotoh, A. Tojo, M. Hino, Y. Yazaki, and M. Shibuya A highly conserved tyrosine residue at codon 845 within the kinase domain is not required for the transforming activity of human epidermal growth factor receptor Biochem. Biophys. Res. Comm. 186 1992 768 774
52. J. Xu, J.E. Yeon, H. Chang, G. Tison, G.J. Chen, and J. Wands Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase J. Biol. Chem. 278 2003 26929 26937
53. Weber IT. Molecular mechanics calculations on Rous sarcoma virus protease with peptide substrates. In: Harrison RW, editor. Protein Sci. 1997;6:2365-74.
54. B. Mahalingam, A. Cuesta-Munoz, E.A. Davis, F.M. Matschinsky, R.W. Harrison, and I.T. Weber Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia Diabetes 48 1999 1698 1705